Articles tagged with Daughter Cells
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A genome-wide analysis of genes that drive cell division in a multicellular organism has been conducted, revealing over 300 genes differentially expressed during the G1 and G2 phases. The study provides a searchable resource for scientists and citizens to explore gene expression in wing discs and cultured cells.
A team of researchers has discovered a cellular factor called Rif1 that regulates the timing of DNA replication, ensuring proper cell division and preventing tumor formation. The study suggests that Rif1 prevents 'DNA replication stress', a process causing genome instability.
Researchers at Karolinska Institutet found that a subtle epigenetic change facilitates structural changes of the centromere prior to cell division, ensuring proper chromosome distribution. This mechanism is highly similar in human cells and yeast cells, suggesting its key role in preventing incorrect chromosome numbers.
A protein called Lis1 regulates asymmetric division of hematopoietic stem cells, ensuring proper blood cell generation. Deleting Lis1 from mouse stem cells accelerates differentiation, leading to a bloodless mouse. The finding has implications for cancer treatment, as cancer stem cells also rely on Lis1.
A team led by Yixian Zheng identified a protein that regulates interactions between kinetochores and microtubules, improving our understanding of chromosome alignment. The study suggests expanding the scope of research to include other cellular components for a deeper understanding of mitosis.
Researchers found that genetic identical bacteria can behave differently after cell division due to unequal distribution of cellular organelles. This diversity is crucial for bacterial survival, allowing populations to adapt to new opportunities and threats.
Researchers used high-resolution 3D imaging to study the disassembly process of the Golgi apparatus during cell division. The results show that the Golgi apparatus is tightly linked to the endoplasmic reticulum (ER) and redistributes into the ER during mitosis, resolving a basic cellular question.
Researchers at IDIBELL describe the key role of separase protein in regulating mitosis and ensuring correct genetic inheritance. The study identifies two new substrates that contribute to the Hippo tumor suppressor pathway, advancing knowledge of this process.
Researchers have discovered that tumour cells adopt the 'break-induced replication' (BIR) pathway to repair damaged replication forks, allowing for genome duplication. This pathway is common in cancer cells but rare in healthy cells, revealing a significant difference between these two types of cells.
ETH Zurich researchers discovered a mechanism that enables yeast cells to memorise 'bad experiences' during reproduction by forming protein aggregates. These aggregates make future mating attempts more difficult, conserving energy and preventing unproductive reproduction. The system appears to be universal and relatively old in evolution.
A study from the University of Pennsylvania has uncovered a mechanism that allows blood stem cells to divide in perpetuity, using the motor protein myosin II. The researchers found that asymmetric division is enabled by myosin IIB, which helps to partition key factors and keep one side as a stem cell.
Scientists at VIB and Ghent University identified a new protein, ERF115 transcription factor, which regulates quiescent center cells. This discovery explains why plants can live for hundreds of years while animals typically do not.
Researchers discovered two variants of Pds5 proteins that modulate cohesins' behavior, essential for proper cell division. Understanding this regulation can improve diagnosis and treatment for cancer patients and Cornelia de Lange Syndrome sufferers.
A team of scientists has identified a potential mechanism for cellular memory, which allows cells to recall the order of transcription factor binding. This discovery sheds light on how cells maintain gene regulation and may have implications for understanding diseases such as cancer.
Researchers have discovered a protein in bacteria that delays cell division when food is abundant, enabling cells to grow to the right size. This understanding may be used to design drugs that stop division entirely and kill bacteria.
A Penn State-led research team found that histone protein changes can control whether a gene functions, with the potential to maintain genetic expression and prevent disease. The study's findings have significant implications for the study of diseases like cancer and understanding cellular behavior.
A team of scientists has discovered a crucial mechanism controlling centriole separation during cell division, shedding light on the process and its potential links to cancer. The study's findings suggest that the dense mass surrounding centrioles, called PCM, plays a key role in regulating their separation.
Researchers Tomomi Kiyomitsu and Iain Cheeseman discovered that human cells use the dynein motor to align their mitotic spindle structure, which is then corrected by cell membrane elongation. This process allows for symmetric cell division in about 95% of cells, resulting in identical daughter cells.
A team of scientists at the Salk Institute found that disrupted micronuclei, which can trigger massive DNA damage on chromosomes, might play an active role in carcinogenesis. They also identified biomarkers to detect these structures, suggesting a new tool for cancer diagnosis.
Stem cells use a process called nonrandom chromosome segregation to divide into different cell types, suggesting that distinct genetic information on the chromosome copies may underlie this diversification. The study used fruit fly stem cells to demonstrate this ability and sheds light on how cells develop into complex organisms.
Researchers at Mount Sinai identified new targets for abnormal cell division, finding that blocking CDK7 can inhibit the activity of other critical enzymes CDK4 and CDK6. This discovery suggests turning off these enzymes may be an effective therapeutic target for preventing cancer cell proliferation.
A UCLA study identified a small molecule that destroys 'problem' pluripotent stem cells, which can develop into unintended cell types. MitoBloCK-6 causes these cells to die by triggering apoptosis, leaving only differentiated cells behind.
Researchers Arshad Desai and Christopher Campbell found that Aurora B kinase congregates on microtubules instead of the centromere, ensuring required tension is achieved on chromosomes. This discovery challenges prevailing model for how dividing cells monitor chromosome distribution.
Researchers at Stanford University School of Medicine have devised a way to mimic the spatially oriented signaling that cells normally experience. They found that the location of a "divide now" signal on the membrane of a human embryonic stem cell governs where in that cell the plane of division occurs.
Researchers at Stanford have developed a light-emitting probe that can be injected into individual cells without harm. The device uses photonic cavities to amplify light and detect specific biomolecules, paving the way for real-time sensing and monitoring of cellular biology.
Researchers have identified how two genes, Ipl1 and Mps1, work together to correct mistakes in chromosome distribution during cell division. This understanding could lead to targeted cancer treatments by controlling these master regulator genes.
Researchers used advanced microscopy to track telomere movement in real-time throughout the cell cycle, finding they move to the outer edge of the nucleus after duplication. This reorganization may help maintain correct gene expression profiles and influence aging and cancer development.
Researchers have discovered a new type of cell division called klerokinesis, which appears to be an evolutionary failsafe mechanism that could rescue cell functions during embryonic development. By analyzing human retinal pigment epithelial cells, the team found that klerokinesis can help maintain genomic integrity and potentially prev...
Researchers at University of Wisconsin-Madison discovered a new form of cell division called klerokinesis, which helps prevent faulty cell division leading to cancer. In experiments with human cells, they observed that cells with extra chromosomes could recover normal sets through klerokinesis, potentially lowering cancer incidence.
The American Society for Cell Biology's Celldance awards recognized top videos showcasing cellular mechanisms in development, health, and disease. Winners included a time-lapse of fruitfly embryonic development and a cancer cell movement video.
Researchers at UGA have found that an algal structure allows parasites like malaria and toxoplasmosis to replicate and spread inside hosts. Altering this fiber may lead to new anti-parasitic treatments.
Researchers found that an ancient algal structure is used by deadly parasites like malaria and toxoplasmosis to replicate inside hosts. Altering this fiber-like structure can prevent parasite replication, potentially leading to new treatments.
Researchers clarify how cells line up at the right time to receive signals about the next phase of their life by visualizing single-cell activity in living zebrafish embryos. The findings increase understanding of cyclical behaviors in all types of cells and could lead to new ways to treat certain human conditions.
Scientists have developed a new video protocol to isolate brain tumor initiating stem cells from primary brain tumors, allowing for quick and efficient analysis of target cells. This approach has been effectively used to identify similar stem cells in leukemia patients.
A new study reveals that clathrin protein moonlights as a key player in cell division, shedding light on the process and potential links to cancer. By deleting clathrin from cells, researchers found that it stabilizes centrosomes, which are essential for proper chromosome segregation.
Scientists at Cold Spring Harbor Laboratory link gene mutations in Orc1 protein to extreme dwarfism and small brain size in Meier-Gorlin syndrome. The study reveals that centrosome reduplication and dysregulation of DNA replication contribute to severe manifestations of the rare condition.
An international team of scientists found that asymmetric division of antibody-producing B cells speeds up the body's immune defenses by creating optimized antibodies. This process, called the 'recycling hypothesis,' allows the immune system to produce highly effective antibodies against specific pathogens.
Researchers from IDIBELL have discovered a new mechanism in cell division regulation through protein Zds1. This finding has significant implications for developing targeted and direct therapies against cancer by understanding the molecular mechanisms of mitosis.
A DNA replication protein called Cdt1 is involved in both DNA replication and mitosis, a later step of the cell cycle. This discovery provides a possible explanation for why many cancers have genomic instability and an abnormal number of chromosomes.
Researchers at the University of Warwick discovered the precise mechanism by which spindle checkpoint proteins bind chromosomes. This breakthrough understanding could lead to the development of more selective and effective cancer drugs, potentially reducing debilitating side effects.
Studies on Drosophila melanogaster have provided insights into human stem cell development, particularly in the formation of specialized cells. The research also explores the role of membrane lipids in establishing polarity in sperm cells, which may contribute to cancer progression.
Researchers at UCLA have discovered that two-way signaling between niche cells, the progenitor cells themselves, and their daughter blood cells is necessary for maintaining a balanced population of blood cells. This balance ensures the creation and maintenance of the blood supply in Drosophila fruit flies.
Researchers at Penn Medicine discovered that B cells can produce unequal daughter cells through a process involving helper T cells and specific proteins. This finding may explain how lifelong antibodies are generated after vaccination, and could also shed light on the development of cancerous blood cells like leukemia.
Researchers discovered that mycobacterial cell growth patterns determine their susceptibility to antibiotics, providing new avenues for targeted treatment. The findings could lead to more effective treatments for the deadly disease, which kills over 1.5 million people annually.
Researchers at the Instituto Gulbenkian de Ciencia have uncovered a molecular mechanism that enables cells to accurately inherit non-genetic information, such as protein structures. This epigenetic memory is crucial for maintaining genome organization and preventing errors in cell division, which can lead to cancer.
Researchers identified STARD9, a kinesin-like protein involved in cell division, as a potential target for cancer therapy. Depleting STARD9 stops cancer cells from dividing and causes them to die quickly, showing promise in treating certain types of melanoma and non-small cell lung cancers.
Researchers at Stowers Institute for Medical Research discovered that aging yeast cells retain protein aggregates in mother cells during cell division, preventing them from passing on to daughters. This process is facilitated by the limited mobility of protein aggregates and the narrow opening of the bud neck.
Scientists at University of Warwick discover mechanism for cell division ensuring correct chromosome number, a key factor in cancer development. The study found that the 'spindle checkpoint' is conserved from yeast to human cells and can be targeted by drugs to prevent cancer.
A study by University of California, San Diego biologists reveals that bacteria age and use asymmetric division to improve population fitness. By giving more cellular damage to one daughter cell and less to the other, bacteria allow for rejuvenation and diversity in their reproductive investment.
Researchers at Washington University in St. Louis have identified seven genes encoding mechanosensitive channels in Arabidopsis thaliana, a small flowering plant related to mustard and cabbage. These channels are believed to play a crucial role in plant movement and response to physical stimuli.
A recent study published in Nature Cell Biology has discovered that bookmarking genes before cell division accelerates their reactivation afterwards. By analyzing the kinetics of gene activation, researchers found that a histone molecule undergoes chemical modification and is preserved during mitosis, allowing for rapid reactivation.
Scientists have developed a novel technique to measure and document tumor-inducing changes in DNA, revealing the earliest stages of cancer formation. The study provides insight into chromosomal rearrangements known as translocations, which can lead to tumors in leukemias, lymphomas, and sarcomas.
Scientists at Norwich BioScience Institutes discovered that plant pores, essential for life and carbon cycles, are evenly spaced due to a specific protein called SPEECHLESS. This protein's activity helps create an even spatial pattern during plant growth, allowing plants to breathe efficiently in different environments.
Researchers at Caltech used powerful imaging technique to study Acetonema longum, a bacterium with two membranes that responds to extreme situations by forming protective spores. The study found that the outer membrane may have originated from an inner membrane during sporulation, providing insights into its evolution and function.
Researchers have discovered a key mechanism controlling the segregation of genetic material from parent to daughter cells. The study found that degradation of CenH3 protein is essential for limiting its presence at centromeres and that this degradation is mediated by protein partner Ppa.
Scientists have discovered a mechanism for epigenetic memory in plants, which affects the timing of flowering based on environmental conditions. The study reveals that histone modifications can be passed on to offspring, providing a new understanding of how organisms 'remember' their environment.
Researchers have discovered new functions of Aurora enzymes in fission yeast, which could lead to improved cancer treatments. The study used phosphoproteomics to identify dozens of new substrates for the enzymes, revealing roles in chromatin regulation and DNA protection.
A team of researchers has made a breakthrough in understanding the assembly of centromeres in human cells, revealing an essential division of labor among specific proteins. By visualizing these proteins in living cells, they discovered that certain proteins like CENP-A play a crucial role in carrying genetic information to the centromere.
Scientists use new technique to demonstrate that cell membrane and cytoplasm structure can guide asymmetric cell division. Model cells show that simple chemical interactions can result in complex behaviors like asymmetric division even without genetic signals.
Researchers found that zebrafish fin regeneration relies on multiple cell types, each retaining its original identity, rather than a single pluripotent stem cell. This discovery has implications for regenerative medicine in humans.