Deubiquitination | Topics

Articles tagged with Deubiquitination

Study uncovers the mechanisms behind tumour suppressor BAP1 protein, highlighting new treatment strategies for aggressive cancers

Researchers have uncovered how BAP1 functions at the molecular level and present a novel therapeutic strategy to slow cancer progression. BAP1's role in DNA repair pathways and its potential as a biomarker for personalized treatment are also explored.

Promising Parkinson's drug decoded

A new study reveals how a promising Parkinson's drug works by inhibiting the enzyme USP30, which prevents damaged mitochondria from being degraded. This breakthrough could lead to targeted therapies for Parkinson's disease and chronic kidney disease.

Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Molecular gardening: New enzymes discovered for protein modification pruning

Researchers have identified two new deubiquitinases, USP53 and USP54, which play a crucial role in removing polyubiquitin tags from proteins. This study suggests that mutations in the USP53 gene are associated with paediatric cholestasis, highlighting the potential for targeted treatment.