Articles tagged with Liposomes
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Researchers have developed synthetic biomaterials that mimic cellular membranes, showing promise in targeted delivery of cancer drugs and gene therapy. The new materials, called dendrimersomes, offer stability, mechanical strength, and tunable properties.
Researchers at NIST and University of Maryland have developed a microfluidic method called COMMAND to produce uniform liposomes with controlled sizes. The technique uses a microscopic fluidic device to mix phospholipid molecules, resulting in nanoscale vesicles that can deliver drugs directly to cancer cells.
Researchers at University of Illinois create a new cancer drug delivery system using aptamers, achieving high cell killing efficiency while sparing healthy cells. The approach integrates small molecules and antibodies, offering a general toolbox for treating various cancers.
Scientists have created a microcontainer that can hold thousands of individual 'carrier units' - a 'capsosome'. These are polymer capsules with embedded liposomes, combining the advantages of both systems. The capsosomes were produced by several steps and demonstrated successful transport of an enzyme model cargo.
Researchers used contrast agents in liposomes to determine if they could breach breast tumors. Tumors with better images of the contrast agents showed better therapeutic results when treated with a cancer drug called liposomal doxorubicin.
Researchers at Duke University have made a major advance in understanding how bacteria divide, paving the way for new antibiotic treatments. They created an artificial system that demonstrates the importance of FtsZ protein in bacterial cell division.
Purdue University has been awarded $7 million to study the use of a nanomotor, a microscopic biological machine, for diagnosing and treating diseases like cancer and AIDS. The team will adapt a viral motor to package therapeutic DNA or RNA for disease-causing cells.
A team of researchers has successfully produced large, porous, hollow platinum spheres by using liposomes as blueprints. The spheres are made of continuous, branched platinum sheets and have potential applications in biomedical, catalytic, and optical fields.
Researchers at the University of Texas M. D. Anderson Cancer Center have developed a nanoparticle delivery system that targets ovarian cancer cells, reducing tumor size and incidence by up to 98%. The fatty spheres loaded with siRNA also attack the tumor's blood supply, inducing cell suicide and increasing cell death among cancer cells.
Researchers developed RGD peptide liposomes to deliver dexamethasone phosphate directly to VECs at sites of inflammation, reducing arthritis severity and disease progression. The study demonstrates the potential of targeted liposomal therapy for treating rheumatoid arthritis.
Researchers at Penn State have developed a new ceramide-based therapy that targets and destroys breast cancer cells while sparing healthy tissue. The treatment uses liposomes to deliver ceramide to the tumor, where it disrupts mitochondria and causes cell death.
Researchers at Arizona State University found that liposomes form microtubules under low electric fields, which may have significant implications for cellular biology and nanotechnology. The discovery could lead to new methods for fabricating bionanotubes.
Researchers used transferrin protein to attach medicines to iron-containing proteins, allowing them to pass through the blood-brain barrier. This technique enables larger molecules to reach the brain, opening up new possibilities for treating brain diseases.
Researchers at NIST have developed a new method for producing uniform, self-assembled nanocells using micrometer-size channels. These nanocells can be controlled to specific sizes and are ideal for encapsulating medicine, leading to more accurate drug delivery.
Researchers developed ultrasound-guided liposomes to boost imaging and target drug/gene therapy. The technique directs liposomes to specific targets, such as atherosclerotic plaques or blood clots, and releases drugs with ultrasonic pulses, improving visualization and diagnosis of arterial conditions.
Scientists at NIST have developed an improved method for using liposomes as tiny test tubes for ultrasmall volume chemistry. This approach may be useful for studying cellular-level processes and identifying new pharmaceuticals more efficiently.
Researchers have developed a three-way drug delivery system using vesicles, allowing for the simultaneous release of different materials in a single vehicle. This innovation could minimize toxic side effects and enhance the effectiveness of medications.
Researchers at Case Western Reserve University are developing an innovative drug delivery device using liposomes to target damaged areas of arteries in cardiovascular disease. The device aims to improve treatment outcomes and reduce mortality rates associated with cardiovascular disease.
A heat-sensitive liposome has been shown to triple the amount of an anti-cancer drug delivered to tumors in mice compared to other liposome-based methods. The liposome releases its cargo rapidly and effectively, increasing the functional concentration of the drug in the tumor.
Researchers at Duke University developed heat-triggered liposomes that can deliver anti-cancer drugs to tumors, delaying growth and eradicating human tumors in mice. The new technology uses specially engineered liposomes that release their cargo rapidly when heated to temperatures just above normal body temperature.
Researchers have developed a technique using liposomes that can detect metal ions in solution, leading to practical sensors for heavy metals, viruses, and environmental cleanup. The technique involves entrapping liposomes in sol-gels, which increases their sensitivity, making them suitable for use in various applications.