Articles tagged with Neurites
Researchers developed an advanced organoid model for human spinal cord injury and tested a promising regenerative therapy. The treatment triggered neurite growth and reduced scarring in injured organoids, offering validation for its potential to work in humans.
Aging is harsh on the hippocampus, a region responsible for learning and memory. Researchers at UCSF identified protein FTL1, which slows cognitive decline in mice by increasing metabolism. Treating with a compound that stimulates metabolism prevents these effects. The study offers hope for therapies to block FTL1's impact.
Scientists found that parts of human chromosomes have evolved rapidly to enable complex brain development in humans. However, this acceleration may also lead to neurodevelopmental disorders like autism. The study used artificial neurons derived from human and chimpanzee cell lines.
Researchers discovered a process called neuritosis, where damaged mitochondria lead to neuronal disconnection and death in neurodegenerative diseases. This discovery opens new targets for therapy, as preserving mitochondrial health may prevent disease progression.
A team of researchers has identified a mechanism regulating the regeneration of neural pathway insulation. The discovery highlights the significance of the Vav3 exchange factor in controlling molecular switches that activate and deactivate signaling processes.
A new device has been developed to perform high-throughput 3D chemotactic assays, revealing diversity and complexity in the chemotactic regulation of neuronal development by various guidance molecules. The platform uses a hydrogel-based microfluidic system to test hundreds of suspended microscale hydrogel cylinders with distinct gradie...
A new study finds that bipolar patients' blood is toxic to brain cells and affects neuron connectivity. The more episodes a patient has, the more cellular components are produced that impair the brain's ability to deal with environmental changes.
Researchers found that Rho kinase regulates rat hippocampal neurite growth and microtubule formation by redistributing vinculin. The study used the ROCK inhibitor Y-27632 to reverse inhibitory effects of lysophosphatidic acid on neurite outgrowth.
Researchers are exploring new approaches to cure stroke by unlocking the brain's regenerative potential. The goal is to develop a novel stroke therapy for humans using newly identified treatments.
Researchers identified ADF and cofilin as crucial proteins in the shape change of young brain cells, enabling them to develop connections with other cells. The study found that these proteins facilitate neurite formation, which is essential for brain development and regeneration.
Researchers developed a biodegradable polymer containing acetylcholine-mimicking groups to stimulate neurite growth and guide nerve regeneration. The biomaterial promotes neuronal activity, enhancing recovery of sensory, motor, cognitive, or autonomic functions after central nervous system injury.
Researchers at UC San Diego discovered that iron oxide nanoparticles can be toxic to nerve cells and interfere with their signal-transmitting extensions. The nanoparticles were initially investigated as a possible way to manipulate nerve cells remotely with magnetic force.
Scientists at Emory University Health Sciences Center have identified the protein HAP1 as crucial for neuronal function and trafficking. The discovery may lead to new treatments for Huntington's disease by understanding how mutant huntingtin affects cellular transport. Research has implications for other neurodegenerative disorders.