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Alpha-synuclein effects on dopaminergic neurons: Protection or damage?

A recent study published in Neural Regeneration Research reveals that alpha-synuclein can have neuroprotective effects on dopaminergic neurons at very low concentrations. The findings suggest that extracellular alpha-synuclein may enhance neuronal survival via the Akt pathway, challenging previous views of its role in Parkinson's disease.

SourceNeural Regeneration Research·JournalNeural Regeneration Research·DateMar 12, 2014