Articles tagged with Osteoblasts
The overproduction of noggin during aging may result in impaired bone building and function, leading to net bone loss. Researchers suggest that recombinant BMP2 may prove useful in reversing age-related bone loss.
IGFBP-5 promotes osteoblast function and bone formation in a manner distinct from IGF-I. The protein interacts with a receptor on osteoblasts to regulate cell growth and activity.
Researchers found that alcohol feeding impaired osteoblast function and led to increased bone turnover, contributing to bone fragility. In contrast, mice lacking the interleukin-6 (IL-6) gene had better maintained bone mass and reduced fractures.