IGF-binding protein-5 as a growth factor in its own right
IGFBP-5 promotes osteoblast function and bone formation in a manner distinct from IGF-I. The protein interacts with a receptor on osteoblasts to regulate cell growth and activity.
Osteoblasts
Articles tagged with Osteoblasts
Alcohol and bone fragility
Researchers found that alcohol feeding impaired osteoblast function and led to increased bone turnover, contributing to bone fragility. In contrast, mice lacking the interleukin-6 (IL-6) gene had better maintained bone mass and reduced fractures.