Add BrightSurf on Google Email

Scientists identify possible cause of endometriosis

Researchers at the University of Liverpool discovered that an enzyme called telomerase is released by cells in the inner lining of the womb during the menstrual cycle, contributing to endometriosis. The abnormal length of telomeres and expression of telomerase in endometrial cells may lead to severe pain and infertility.

SourceUniversity of Liverpool·JournalHuman Reproduction·DateAug 5, 2008

Mutant testis cells behind genetic disorder have survival advantage

A new study found that mutant testis cells carrying the Apert's syndrome mutation have a selective advantage over non-mutant cells, leading to an exponential increase in sperm from older men containing the mutation. This explains why children born from sperm of older fathers are more likely to inherit genetic disorders.

SourceUniversity of Southern California·JournalProceedings of the National Academy of Sciences·DateJul 14, 2008

Couples with fertility problems where the man is over 35 have increased difficulty in conceiving

A recent study by Dr. Stéphanie Belloc found that men over 35 have a negative impact on pregnancy rates and increase miscarriage risks in women undergoing intrauterine inseminations (IUIs). This marks the first time a strong paternal effect has been shown, contradicting previous assumptions about the role of the father in fertility.

Overweight does not decrease sperm production

A new study by The Endocrine Society found that overweight men are not more likely to be infertile, contradicting previous research on obese women. Greater body weight was linked to lower testosterone levels in some participants, but impaired sperm production remains the primary cause of infertility in men.

SourceThe Endocrine Society·JournalThe Journal of Clinical Endocrinology & Metabolism·DateJun 15, 2008

Male painters exposed to fertility damaging chemicals

A study published in Occupational Environmental Medicine found that men working as painters and decorators who are exposed to glycol ethers have poor semen quality. The researchers discovered that these workers have a 2.5-fold increased risk of having a low motile sperm count compared to those with low exposure.

SourceUniversity of Sheffield·JournalOccupational and Environmental Medicine·DateMay 23, 2008

Pinpointing when you become a man

A study in rats reveals that the 'male' hormone-driven decision to become male occurs before genitalia development. Measuring AGD in neonates could predict reproductive disorders like cryptorchidism and low sperm count.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateMar 13, 2008

Why your fertility cells must have 'radio silence'

Scientists have uncovered a previously unknown mechanism that causes embryonic germ cells to go through a period of transcriptional silence, preventing the production of sperm or eggs. This regulation is crucial for germ cell development in various organisms and may hold significance for mammals as well.

SourceMcGill University·JournalNature·DateJan 29, 2008

New cell death pathway involved in sperm development

Researchers have uncovered a new pathway that regulates killer proteins called caspases, which are essential for trimming down heavy sperm to make them better swimmers. This discovery provides insights into the causes of human infertility and opens up opportunities for developing drugs that can alter cell death for therapeutic purposes.

SourceRockefeller University·JournalPLOS Biology·DateSep 17, 2007

Sperm abnormalities seen in male lupus patients

A new study found that male lupus patients have high frequency of sperm abnormalities associated with reduced testicular volume. Treatment with IV CYC was identified as the major factor in permanent damage to the testes, leading to lower median testicular volumes and semen abnormalities.

SourceWiley·JournalArthritis & Rheumatism·DateJun 28, 2007

Researchers find gene that spurs development of the epididymis

A team of researchers at the University of Illinois has discovered a key gene involved in the development of the epididymis, a critical structure for sperm fertility. The gene, inhibin beta A, plays a vital role in stimulating cell growth and differentiation, leading to the formation of the epididymal tube.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalProceedings of the National Academy of Sciences·DateJun 27, 2007

Scent prediction

An interdisciplinary team predicts the scent intensity of lily-of-the-valley fragrance components using a computer model of their olfactory receptors. The study confirms that electronic surface structures determine the interaction between scented molecules and human scent receptors.

SourceWiley·DateApr 18, 2007

Link between beef consumption during pregnancy and reduced sperm quality in sons

Research found that pregnant women who ate more than seven beef meals a week had sons with lower sperm concentrations and higher rates of sub-fertility. The study suggests a link between maternal beef consumption and reduced fertility in sons, potentially due to the presence of anabolic steroids and other xenobiotics in beef.