Articles tagged with Sperm
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Jackson Laboratory scientists have developed a simple and cost-effective method to freeze mouse sperm, achieving high fertilization rates with mouse eggs. This breakthrough will significantly reduce the cost of developing new mouse models for human diseases.
A team of biologists has identified a collection of novel proteins transferred from male to female fruit flies during mating, which influence female behavior and favor male success. The study reveals that these proteins are rapidly evolving and potentially under intense selection pressure.
Men who consume soy foods regularly have lower sperm concentrations than those who do not. The association is particularly strong in overweight or obese individuals. Researchers found that men with normal or high sperm counts may be more susceptible to the effects of soy foods, suggesting a possible increased risk of infertility.
A minimally invasive treatment called venous embolization has been shown to significantly improve a couple's chances of pregnancy in infertile men. The study found that patients with high sperm motility prior to treatment had the highest success rates, with over 26% of couples becoming pregnant after six months.
A team of scientists at the Salk Institute found that specialized testis niche cells in fruit flies originate from adult stem cells. This breakthrough has implications for regenerative medicine, aging research, and cancer therapeutics. The study suggests that once a fly becomes an adult, some stem cells can replace their supporting nic...
A new study found that mutant testis cells carrying the Apert's syndrome mutation have a selective advantage over non-mutant cells, leading to an exponential increase in sperm from older men containing the mutation. This explains why children born from sperm of older fathers are more likely to inherit genetic disorders.
Research by Dr. A Ghiyath Shayeb found that obese men had lower semen volumes and higher proportions of abnormal sperm. Men with a healthy BMI, however, had better semen quality. The study suggests that achieving an ideal body weight before trying for a baby can improve fertility outcomes.
A study by Dr. Con Mallidis from Queen's University, Belfast, UK, found that diabetes causes DNA damage in sperm and decreases their ability to repair DNA, leading to decreased fertility. The researchers identified AGEs as a key factor in this damage.
Research finds that many normal-looking sperm used in ICSI have DNA damage, decreasing pregnancy chances and increasing risk of miscarriage. The study urges for more careful selection methods to avoid problems in the future.
A recent study by Dr. Stéphanie Belloc found that men over 35 have a negative impact on pregnancy rates and increase miscarriage risks in women undergoing intrauterine inseminations (IUIs). This marks the first time a strong paternal effect has been shown, contradicting previous assumptions about the role of the father in fertility.
A new study reveals that lactate dehydrogenase C (LDHC) enzyme plays a critical role in male fertility, affecting sperm motility and ATP production. Meanwhile, research on polycystic ovary syndrome (PCOS) suggests prenatal exposure to androgens may contribute to infertility symptoms.
A new study by The Endocrine Society found that overweight men are not more likely to be infertile, contradicting previous research on obese women. Greater body weight was linked to lower testosterone levels in some participants, but impaired sperm production remains the primary cause of infertility in men.
A study published in Occupational Environmental Medicine found that men working as painters and decorators who are exposed to glycol ethers have poor semen quality. The researchers discovered that these workers have a 2.5-fold increased risk of having a low motile sperm count compared to those with low exposure.
A new method for handling rape kit evidence developed by Jessica Voorhees Norris reduces DNA analysis time and improves sperm cell recovery rate by 100 percent. This could potentially reduce the nationwide backlog of unanalyzed samples in US forensic laboratories.
Researchers from UT Southwestern Medical Center have found that the malaria parasite uses a two-step process for reproduction, which could lead to a new type of vaccine. By blocking one protein, they were able to stop the spread of the disease in mice and mosquitoes.
A new study found that men with lower folate intake have higher rates of chromosomal abnormalities in their sperm, which could affect reproductive health and birth outcomes. Higher folate intake was associated with lower rates of these abnormalities.
Researchers found an association between high folate intake and lower levels of chromosomal abnormalities in men's sperm. The study suggests that increasing folate intake through diet or supplements may reduce the risk of chromosomal abnormalities in children.
A study in rats reveals that the 'male' hormone-driven decision to become male occurs before genitalia development. Measuring AGD in neonates could predict reproductive disorders like cryptorchidism and low sperm count.
Research found teenage fathers more likely to have babies with birth problems such as pre-term delivery, low birth weight, and death. In contrast, older fathers aged 40+ were not at increased risk, according to the European Society of Human Reproduction and Embryology study.
Scientists have uncovered a previously unknown mechanism that causes embryonic germ cells to go through a period of transcriptional silence, preventing the production of sperm or eggs. This regulation is crucial for germ cell development in various organisms and may hold significance for mammals as well.
Field mice have sacrificed immunity protection to develop faster fertilization, resulting in instability of the sperm's acrosome. This process may provide insight into human infertility, as humans lack this rapid reaction.
Researchers at the University of California, San Diego, have identified a unique plant gene that prevents fertilization when mutations are present in both the male and female reproductive cells. The discovery, known as 'abstinence by mutual consent,' reveals a previously unknown mechanism in plant reproduction.
A study published in PLoS Genetics identified five seminal proteins necessary to elevate offspring production in mated females. These proteins modulate egg production, sperm storage and release, as well as female post-mating behavior and physiology.
A recent study suggests that sugar-based markers on human sperm cells could provide insights into how some cancers evade the immune system. These markers, found on N-glycans and recognized by all human immune systems, may be universally used by cancer cells to avoid destruction.
Researchers at USC suggest epigenetics plays a role in male infertility, with abnormal DNA methylation linked to low sperm counts. The study finds high levels of methylation in sperm DNA from men with fertility issues, potentially leading to new treatments for male infertility.
Scientists at Cornell's Baker Institute of Animal Health have successfully assembled and functioned a human-made device that mimics the biological pathway powering sperm, which could be used to release drugs or perform mechanical functions inside the body. The device uses a nickel-NTA chip to replicate the glycolysis pathway, allowing ...
A recent study published in Nature Genetics analyzed mutant sperm cells to identify genes involved in disease, revealing that duplications are less frequent than deletions in certain regions. The findings suggest improved diagnosis for genomic diseases and a new approach to predicting disease-causing variants.
Scientists report biochemical proof that female mammals can sense sperm presence and alter uterine environment to favor fertilization. This discovery has profound implications for in-vitro fertilization, cloning, and animal breeding.
Scientists have identified a crucial gene, Jhdm2a, that triggers the final step of sperm cell formation. Mice lacking this gene exhibit significant male infertility symptoms. The study provides evidence that Jhdm2a controls expression of genes required for DNA packaging in sperm cells.
Varicocele removal significantly improves testosterone levels in over two-thirds of men, leading to improved fertility and reduced symptoms of andropause such as low sex drive and depression.
Researchers have made significant breakthroughs in developing new male contraceptives, including a hormone-based regimen that worked in 90% of men, a vasectomy alternative with high success rates, and a vitamin A-blocking drug that showed no health effects. These advancements offer hope for men seeking reliable birth control options.
Researchers at the NIH conference present advances in male contraception, including a non-hormonal pill and a testosterone-like treatment. These developments aim to provide men with more control over their fertility, offering an alternative to existing methods like condoms and vasectomy.
Research finds that sperm cells from more promiscuous primate species swim faster and with greater force than those of monogamous species. Human sperm fall in between, suggesting they may not have always been as monogamous as thought.
Scientists have successfully reprogrammed adult stem cells from male mice' testes into functional blood vessels and cardiac tissue. These multipotent adult spermatogonial-derived stem cells may offer an alternative to embryonic stem cells without ethical concerns.
Researchers have uncovered a new pathway that regulates killer proteins called caspases, which are essential for trimming down heavy sperm to make them better swimmers. This discovery provides insights into the causes of human infertility and opens up opportunities for developing drugs that can alter cell death for therapeutic purposes.
Professor Andrew Steckl's innovative approach incorporates DNA from salmon sperm into light-emitting diodes, enhancing performance while reducing environmental impact. The technique involves trapping electrons longer, resulting in brighter colors and improved light efficiency.
Researchers have identified radial spoke protein 44 (RSP44) as a key molecule in immune infertility, a condition causing the immune system to attack sperm. The discovery may lead to new diagnostic tools and treatments for this condition, which affects up to 12% of unexplained infertility cases in women.
Researchers find Apert's syndrome is perpetuated due to mutant cells out-replicating normal cells in testes, leading to higher transmission rates. The single base-pair mutation occurs at a frequency 100-1000 times higher than predicted standard mutation rate.
Research suggests that human testes can multiply mutations, making it easier for disease-causing genes to be passed to offspring. This phenomenon could explain why certain genetic disorders, such as Apert syndrome, occur more frequently than expected.
Researchers at USC develop a miniaturized camera for implantable retinal prostheses, achieving good results with just 625 pixels. The new LIDAR system uses near-infrared light to detect atmospheric conditions, providing pilots with better visibility in foggy and hazy environments.
A recent study by McMaster University shows that sperm banking can preserve fertility in adolescents and young adult males with cancer. The study found a 36% success rate using intrauterine insemination and a 50% success rate using in vitro fertilization.
Researchers at Weill Medical College have successfully cloned a mouse genome, paving the way for potential treatment of low sperm count in infertile men. The technique involves replicating the male genome, which could increase chances of conception and reduce embryo wastage.
A new study found that male lupus patients have high frequency of sperm abnormalities associated with reduced testicular volume. Treatment with IV CYC was identified as the major factor in permanent damage to the testes, leading to lower median testicular volumes and semen abnormalities.
A team of researchers at the University of Illinois has discovered a key gene involved in the development of the epididymis, a critical structure for sperm fertility. The gene, inhibin beta A, plays a vital role in stimulating cell growth and differentiation, leading to the formation of the epididymal tube.
Research shows that diabetic men's sperm have greater levels of DNA damage, which may affect fertility. Sperm from diabetic men had higher fragmentation rates and more deletions of DNA in mitochondria compared to non-diabetic men.
Researchers identified a new protein involved in egg activation and its role in fertilization. A chemical has been found effective against anthrax by blocking spore germination. A new protein also controls the growth of the hepatitis C virus, which could lead to new drug development.
An interdisciplinary team predicts the scent intensity of lily-of-the-valley fragrance components using a computer model of their olfactory receptors. The study confirms that electronic surface structures determine the interaction between scented molecules and human scent receptors.
A study by the University of Rochester Medical Center found a significant link between high maternal beef consumption and lower sperm counts in sons. The study suggests that prenatal exposure to anabolic hormones from beef may alter sperm production in the male fetus, leading to reduced semen quality.
Research found that pregnant women who ate more than seven beef meals a week had sons with lower sperm concentrations and higher rates of sub-fertility. The study suggests a link between maternal beef consumption and reduced fertility in sons, potentially due to the presence of anabolic steroids and other xenobiotics in beef.
Researchers have identified a vital protein, PAWP, essential to human reproduction and fertilization. The study suggests that regulating this protein may increase the chances of pregnancy by enhancing fertility.
Researchers successfully tag sperm whales and jumbo squid swimming together, providing new insights into the diving behavior of both species. The study, published in Marine Ecology Progress Series, raises questions about the feeding habits and hunting strategies of sperm whales and their prey.
Researchers discovered that male wasp spiders use a 'chastity belt' mechanism to block their female partner's sexual orifice during copulation, preventing offspring from other males. The detached genital tip plugs the orifice securely, impeding further copulation.
A new study published in International Braz J Urol found that exposure to hot baths or hot tubs can lead to male infertility. However, the effects can be reversible if the practice is discontinued for at least three months. The study showed a significant increase in sperm motility among responders, with a mean increase of 491 percent a...
A new study suggests that human males have evolved mechanisms to outcompete rivals for fertilization, even after sex. This phenomenon, dubbed 'sperm competition,' can lead to increased sperm count and more aggressive sexual behavior in response to perceived infidelity.
In promiscuous rodents, individual sperm work together in groups to increase competitiveness and successfully reach the female egg. This cooperation enables faster and stronger swimming, making them better competitors in fertilization races.
A survey of 129 men with testicular cancer found that 24% chose to bank their sperm before treatment, despite high costs and relatively low usage. Single men were twice as likely to bank their sperm, and those who did had better fertility outcomes after treatment.
A new protein called sperm flagellar energy carrier (SFEC) has been discovered in the sperm tail, which may play a role in disabling sperm swimming. The discovery is significant because SFEC is linked to glycolysis, a process that produces energy in the sperm's tail.
Researchers identified a male-specific gene, PlestMID, in an oogamous green algae species that evolved from its isogamous ancestor's dominant sex. This breakthrough provides insights into the evolution of male-female dichotomy and the origin of distinct sperm and egg cells.
Researchers explore using tardigrade-produced trehalose to preserve human eggs, offering a potential solution to successful embryo cryopreservation. The method has shown promising results in mouse eggs, and further research aims to apply it to human eggs and endangered species.
A study at the University at Buffalo found that synthetic cannabinoid AM-1346 can improve fertility in male smokers with poor semen quality, doubling fertilizing capacity. Researchers believe a communication imbalance between cannabinoid and cholinergic receptor systems may be responsible for nicotine-induced infertility.