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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Cumulative sperm whale bone damage and the bends

Research found lesions on sperm whale bones increase with age and size, suggesting chronic decompression damage. Nitrogen gas bubbles from sonar or seismic survey guns may cause acute problems in whales.

DJI Air 3 (RC-N2)

DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

Scientists discover key egg enzyme for blocking sperm entry after fertilization

Researchers at Brown University have identified an enzyme called Udx1 that generates hydrogen peroxide to block sperm entry and protect the fragile embryo. The discovery sheds light on a century-old mystery of how eggs defend themselves against sperm, with potential implications for understanding fertilization and early development.

Sperm enzyme is essential for male fertility, study shows

Researchers found that sperm motility and ATP production depend on a metabolic pathway called glycolysis, which uses sugar to produce energy. Without the enzyme glyceraldehyde 3-phosphate dehydrogenase-S (GAPDS), sperm movement is severely impaired, making it a potential target for non-hormonal male contraceptives.

Reassuring findings from first study on sperm donor identification

A study of 29 adolescents who had been conceived through 'open-identity' sperm donors found that all but one young person had a neutral or positive response to their origins. The majority expressed curiosity about their donor and sought a connection, not a paternal relationship. This finding contradicts stereotypes and suggests that op...

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Researchers grow sperm stem cells in laboratory cultures

Scientists have successfully grown sperm progenitor cells in a laboratory culture, paving the way for potential new treatments for male infertility. The breakthrough, led by Hiroshi Kubota, could also enable the creation of genetically modified animals and extend the reproductive life of endangered species.

Growth factors confer immortality to sperm-generating stem cells

Researchers at the University of Pennsylvania School of Veterinary Medicine have identified key growth factors essential for sustaining spermatogonial stem cells in culture. By understanding these factors, scientists hope to develop new fertility therapies and create sperm in vitro.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Jumping gene plays pivotal role in reproduction

A jumping gene called mUtp14b has been found to affect fertility in mice, with a mutation leading to sterility. Researchers believe this gene may play a role in male infertility in humans and are investigating its potential impact.

Noah's modern ark: The role of ART in conserving endangered species

The use of artificial reproduction technologies in wildlife conservation aims to understand fundamental reproductive mechanisms in various species. Dr. David Wildt highlights the importance of collaboration between specialists from different disciplines to achieve genuine conservation.

Need sex? It's probably something about stress

In Volvox carteri, colonies become sexual when exposed to high temperatures, releasing pheromones to guarantee mating partners. This response is linked to the activation of the sex-inducer gene, which promotes the production of a pheromone in reaction to increased oxidants produced by free radicals.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

Baby born from sperm frozen for record 21 years

A healthy baby boy was born to a couple after the father's sperm was successfully frozen for 21 years. ICSI technique used for fertilization, resulting in high motile sperm percentage after thawing. Long-term storage preserved fertility quality, offering hope for young cancer patients seeking family planning.

Genomic imprinting in disruptive spermatogenesis

Research finds a correlation between disrupted spermatogenesis and abnormal genomic imprinting in men with low sperm counts. The study suggests that spermatozoa from oligozoospermic patients carry an increased risk of transmitting imprinting errors.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Stem cells toward sperm cells and back again

Scientists at Johns Hopkins Medicine have discovered that lost sperm-making stem cells in fruit flies can be replaced by reversing their specialized state. The team found that temperature changes can trigger a process called dedifferentiation, where more specialized cells retrace the path taken by stem cells.

Frozen, fresh sperm both effective for in vitro fertilization

Researchers at Mayo Clinic found that frozen sperm are just as effective as fresh sperm in in vitro fertilization. The cumulative live birth rate was higher for frozen sperm, with a success rate of 53.1 percent compared to 51.6 percent for fresh sperm.

Freeze-dried sperm can fertilize rabbit oocytes

Researchers successfully fertilized rabbit oocytes with freeze-dried sperm, showing promise for long-term storage. The breakthrough improves upon previous success with mouse sperm and opens up possibilities for preserving sperm from humans and other mammalian species.

Primate testes grafted into mice rapidly produce fertile sperm

Scientists have successfully grafted primate testes into mice, resulting in the rapid production of fertile sperm. This breakthrough could preserve genetic material from endangered nonhuman primates and offer reproductive options to men rendered infertile by cancer treatments.

Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Transgenic animals produced using cultured sperm

Researchers have successfully produced transgenic zebrafish using cultured sperm cells grown in laboratory conditions, enabling the study of human development and disease. The new technique also holds promise for pre-fertilization strategies in human gene therapy, potentially leading to preventive treatment for certain genetic disorders.

Researchers find key gene in production of egg and sperm

A team of biologists at UC Berkeley has found a key gene involved in the first step of meiosis, allowing chromosomes to recognize and pair with their homologs. This discovery is crucial for understanding meiosis in humans and could lead to insights into infertility and genetic diseases.

'Suicide proteins' contribute to sperm creation

Researchers found that multiple caspases and regulators are required for proper sperm formation in fruitflies, highlighting a non-apoptotic process. This discovery could provide insights into male infertility and suggest possible treatments.

Researchers engineer mouse embryonic stem cells to form sperm cell precursors

Scientists have successfully engineered mouse embryonic stem cells into sperm-like cells using laboratory techniques alone. These precursors were then used to fertilize mouse eggs, resulting in the formation of early-stage embryos. The research has potential applications for treating male infertility and studying cancer.

Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

Researchers reveal early steps in clone development

Temple researchers mapped out early embryo development and found that clones replicate the process entirely at this stage. However, cloned embryos bear characteristics of both an embryo and adult cell, leading to slow and incomplete development.

Restricting the gene pool

Researchers have identified a receptor on sea urchin eggs that regulates the species-specific adhesion of sperm, preventing cross-fertilization between different species. The discovery provides insights into the molecular mechanisms of gamete interactions and could shed light on how new species evolved.

Scientists identify new sperm protein required for fertilization

Scientists at Emory University Health Sciences Center have identified a new sperm protein called SED1 that plays a critical role in the initial association between sperm and egg during fertilization. Mice without this protein had reduced fertility despite normal sperm characteristics, highlighting its importance in successful binding.

Disease-causing genetic mutations in sperm increase with men's age

Researchers found that older men's sperm contain more disease-causing genetic mutations, which surprisingly increase the chances of fertilization. The mutations may confer a competitive advantage to the sperm, contributing to the increased incidence of rare genetic diseases in children born to older fathers.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Role reversal: male gets easy ride in insect courtship

Scientists have observed a rare phenomenon in the insect world where a female Zeus bug allows a male to ride on her back, feeding on protein-rich wax produced by the female. This unusual behavior, known as 'female-led mating,' has sparked curiosity among researchers and provides new insights into the evolution of mating behaviors.

Air dried sperm could allow home storage

A new air-drying technique allows stored sperm to be transported without special equipment, relieving laboratories of sperm care. This method also reduces the risk of HIV transmission and gives owners more control over disposal decisions.

Muslims embrace brave new world of IVF

IVF adoption is more accessible in Middle Eastern Muslim countries due to Islamic fatwa declarations. Shi'ite Muslims are permitted to use donor egg and sperm technologies, whereas Sunni Muslims are restricted, leading some men to reassess their marriages.

Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

Short-term exposure to estrogen cuts fish fertility

Research found that short-term exposure to ethynylestradiol reduces sperm fertilization capacity in adult male trout. The study showed a 50% decrease in fertility with 10 nanogram per liter of ethynylestradiol, highlighting the potential impact on fish populations.

Essential gene for male fertility found

Researchers at the University of Toronto have discovered a gene, Fkbp6, essential for male fertility but not female fertility. The study shows that the gene plays a critical role in sperm cell development and chromosome pairing, highlighting potential new principles in how cells control the number of chromosomes.

Italian study finds traffic pollution affects male fertility

A recent Italian study found that men exposed to high levels of traffic pollution have impaired sperm quality and reduced fertility. The research team examined semen samples from 85 motorway tollgate workers and 85 aged-matched controls, revealing deranged sperm parameters below World Health Organisation levels.

Tufts University biologists unveil more mysteries of fireflies’ flash

A study by Tufts University biologists found that female fireflies are attracted to males with longer flashes, indicating they can be better fathers. The length of a male's flash is related to the quality and quantity of his 'nuptial gift', which provides essential nutrition for his offspring.

CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

UCLA biologists elucidate fertilization process

Researchers have found an optimum amount of fluid motion enhances fertilization significantly, applicable to various species including humans. They also discovered a molecule controlling sperm navigation and an inhibitor blocking its effects.

Molecule offers insights into fertilization

A team of scientists has identified a molecule called bourgeonal that activates the human sperm receptor protein, which may play a critical role in fertilization. The discovery could lead to new non-toxic contraceptives and provide valuable insights into chemical communication during fertilization.

Italian research reveals a new twist in the battle of the sexes

Researchers from Italy studied over 14,000 births and found a significant disparity in sex ratios between optimal and sub-optimal reproductive conditions. The study suggests that nature tries to compensate for the vulnerability of male babies by favoring them in favorable months.

Nikon Monarch 5 8x42 Binoculars

Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

New findings confirm male fertility declines with age

A study of 97 healthy men aged 22-80 found significant age-related decreases in semen volume and sperm motility. Semen quality is a proxy for fertility, suggesting that men may become progressively less fertile as they age.

Sperm use heat sensors to find the egg

Researchers at Weizmann Institute find that sperm are attracted to fertilization site by temperature difference. A temperature-driven mechanism, known as thermotaxis, guides the sperm through the fallopian tube and prepares them for penetration of the egg.

Sony Alpha a7 IV (Body Only)

Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.

Worm sex receptor identified

Researchers at Vanderbilt University Medical Center have identified a sperm-sensing receptor in worm eggs, enabling egg maturation and ovulation. The discovery sheds light on reproductive problems in humans, including failed meiosis leading to chromosome instability.

Saving energy for sex

Researchers found that MSP binding to VAB-1 receptor triggers oocyte maturation in C. elegans, promoting successful fertilization. The study reveals an unexpected role for VAB-1 in reproduction.

UCSF study of ancient fly gene offers insights into male fertility

A study by UCSF researchers reveals that the human gene BOULE regulates meiosis in sperm development, a key step in creating sperm and eggs. The finding has significant implications for understanding infertility and developing new treatments, including drugs to assist immature sperm cells or block sperm maturation.

Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Two landmark fertility studies give hope to young male cancer patients

Researchers have successfully transplanted immature mouse and rabbit testicular tissue, resulting in live births and mature sperm production. This breakthrough technique offers new hope for pre-pubertal boys and babies affected by cancer treatment, potentially restoring fertility through autotransplantation.

Research reveals a cellular basis for a male biological clock

A recent study reveals that sperm in men older than 35 show more DNA damage, which could be passed on to offspring. The researchers found that older men have lower motility and more damaged DNA, with fewer apoptotic cells, indicating a decline in the ability of sperm to eliminate damaged cells.

Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.