A recent study reveals that MLKL activation causes direct damage to mitochondria, impairing energy production and leading to functional decline in hematopoietic stem cells. In contrast, deletion or inhibition of MLKL significantly alleviates these defects, suggesting a post-transcriptional mechanism driving HSC aging.
SourceThe Institute of Medical Science, The University of Tokyo·JournalNature Communications·TypeExperimental study·DateApr 16, 2026
Researchers have compiled a comprehensive list of 166 human pluripotent stem cell lines available for clinical applications, guiding researchers and developers in selecting optimal cell lines. The study aims to drive hPSC-derived products towards the clinic, addressing a knowledge gap in off-the-shelf product development.
SourceInternational Society for Stem Cell Research·JournalStem Cell Reports·DateDec 18, 2025
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Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
A new framework outlines crucial validity standards for stem cell technology to study devastating brain disorders, aiming to translate laboratory discoveries into effective treatments. The framework addresses the critical gap in translating genetic discovery to clinical application.
SourceGenomic Press·JournalGenomic Psychiatry·TypeLiterature review·DateJul 15, 2025
The Arc Institute has launched its inaugural Virtual Cell Challenge, a public competition using AI to solve one of biology's biggest challenges. Competitors will train models on gene expression data from over half a billion cells and predict changes in gene activity when individual genes are silenced.
SourceArc Institute·TypeCommentary/editorial·DateJun 26, 2025
Researchers in China have reported the groundbreaking achievement of creating a live birth of a chimeric monkey using embryonic stem cell lines. The study demonstrates the ability of these cells to differentiate into various tissues in vivo, opening up new possibilities for genetic engineering and species conservation. Analysis reveale...
SourceCell Press·JournalCell·TypeExperimental study·DateNov 9, 2023
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Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
Researchers have found that mouse stem cells mimic their parent animals' cold resistance, generating energy differently at low temperatures. This discovery opens up new avenues for studying organ preservation and human hibernation using in vitro models.
Scientists have developed a new method to deliver genetic information to stem cells using nanoparticles coated with a specific polymer, enabling more efficient control over cellular differentiation. This innovation has the potential to improve the efficiency and effectiveness of regenerative medicine treatments.
SourceXi'an Jiaotong-Liverpool University·JournalNano Letters·TypeExperimental study·DateMay 8, 2023
Researchers have generated large-scale muscle-controlling nerve cells from ALS patients, revealing striking differences in gene expression between males and females. The study, published in Neuron, used over 450 lines of stem cells to create motor neurons that can potentially lead to the development of new therapeutics.
SourceCedars-Sinai Medical Center·JournalNeuron·DateFeb 9, 2023
Researchers at the University of Cambridge discovered that nearly three-quarters of stem cell lines carry substantial DNA damage, which could compromise their use in research and cell-based therapies. The study found that whole genome sequencing is essential for confirming if cell lines are usable.
SourceUniversity of Cambridge·JournalNature Genetics·TypeExperimental study·DateAug 11, 2022
Researchers developed a mathematical model to predict the efficiency of nanoparticle delivery into cells, particularly in stem cells. They found that nanoparticles become trapped in bubble-like vesicles, preventing them from reaching their targets.
SourceXi'an Jiaotong-Liverpool University·JournalACS Nano·TypeExperimental study·DateJul 20, 2022
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CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
Researchers have created stem cell models that mimic the genetic disorder, revealing the role of WASP protein in regulating RNA splicing and finding potential therapeutic targets. These findings could lead to new treatments for Wiskott-Aldrich syndrome, a devastating immune deficiency disorder.
SourceKing Abdullah University of Science & Technology (KAUST)·JournalNature Communications·DateJul 6, 2022
Researchers have discovered an alternative route that pluripotent and endoderm extra-embryonic stem cells can use to form intestinal organs in the lab. This finding could lead to improved cell development and potentially treat diseases, but further function testing is needed.
SourceUniversity of Copenhagen - The Faculty of Health and Medical Sciences·JournalNature Cell Biology·TypeExperimental study·DateJun 14, 2022
Researchers monitored cell environments for three days, finding significant differences from native conditions. The team aims to develop recommendations on improving culture conditions and reduce environmental instability.
SourceKing Abdullah University of Science & Technology (KAUST)·JournalCommunications Biology·TypeObservational study·DateFeb 8, 2022
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Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Johns Hopkins Medicine researchers have developed a 3D map of blood vessels and stem cells in a mouse skull, revealing previously unknown niches for stem cell residence. The map provides precise locations of blood vessels and stem cells, which could be used to repair wounds and generate new bone tissue.
SourceJohns Hopkins Medicine·JournalNature Communications·DateNov 18, 2021
Researchers at ETH Zurich developed a new chip-based test that incorporates the placenta into embryotoxicity assessments. The test detects indirect damage to embryos by analyzing stress responses of human placental cells to toxic substances.
Researchers at the University of Bath have developed a bioengineering process that uses grass blades to create scaffolds for animal cells to grow on, resulting in cultured meat. The study successfully demonstrates significant cell adhesion and tissue formation, paving the way for a more sustainable meat production method.
SourceUniversity of Bath·JournalJournal of Biomedical Materials Research·DateJul 1, 2021
Researchers at Skoltech have designed a labeling system for individual cells using polymer multilayer microcapsules that can be easily reproducible and non-toxic. The system allows for the tracking of single-cell behavior and migration with extreme precision, facilitating studies on cell movement and communication in populations.
SourceSkolkovo Institute of Science and Technology (Skoltech)·JournalACS Applied Materials & Interfaces·DateJun 17, 2021
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
Researchers from Utrecht University publish a consensus on what constitutes an organoid, highlighting the importance of using primary cells for personalized therapies. The new system categorizes organoids into three types based on defining characteristics, providing clarity for future research and clinical applications.
SourceUtrecht University·JournalCell Stem Cell·DateMay 6, 2021
Osaka University researchers have generated immortalized human eccrine sweat gland myoepithelial cells (iEM cells), which can be cultured for over ten generations. This achievement has the potential to develop next-generation antiperspirants and promote research on sweat dysfunction and regeneration.
Researchers at Arizona State University have developed a new method called TREE to edit genes implicated in Alzheimer's disease, achieving 90% efficiency in human stem cells. The breakthrough uses base editors to make single DNA edits with high accuracy, paving the way for personalized medicine and disease modeling.
SourceArizona State University·JournalStem Cell Reports·DateJan 30, 2020
Researchers have engineered a human pluripotent stem cell line containing two 'suicide genes' that induce cell death in all but the desired insulin-producing cells. This approach addresses the limitations of PSC-derived beta cells and opens the door to creating safe cell-replacement therapies for people living with type 1 diabetes.
SourceDiabetes Research Institute Foundation·JournalStem Cell Reports·DateFeb 19, 2019
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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers have developed a new method to analyze cardiac muscle cells derived from human pluripotent stem cells, using a non-invasive fluorescence technique that enables faster and more accurate analysis. This breakthrough method uses CRISPR-Cas9 to generate a calcium-indicating reporter stem cell line, which allows for the examinati...
The discovery of human embryonic stem cells in 1998 revolutionized regenerative medicine, with 29 clinical trials underway globally. The field has grown exponentially, enabling large-scale production of pure cells for research, and nearly $1.43 billion spent on NIH stem cell research over the past 20 years.
SourceUniversity of Wisconsin-Madison·JournalCell Stem Cell·DateNov 1, 2018
Researchers at Tohoku University have successfully cultured human placenta stem cells for the first time, opening up new avenues for studying fetal development and maternal health. The study, led by Takahiro Arima, has shed light on the crucial role of trophoblast cells in supporting fetal growth and development.
SourceTohoku University·JournalCell Stem Cell·DateJan 24, 2018
Researchers at The Scripps Research Institute identified the p53 gene as a master regulator of mesenchymal stem cells' ability to differentiate. The study found that a basal level of p53 is required for MSCs to act accurately in the body, and its deletion can lead to unexpected differentiation outcomes.
SourceScripps Research Institute·JournalCell Death and Differentiation·DateJan 22, 2018
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Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
Researchers created Expanded Potential Stem Cells (EPSCs) with greater development potential than current stem cell lines, shedding light on miscarriage and developmental disorders. The EPSCs can develop into any type of cell, offering a platform to study early embryo cells in detail.
SourceWellcome Trust Sanger Institute·JournalNature·DateOct 11, 2017
Researchers have successfully produced functional arterial cells using new techniques, exhibiting key functions required by the body. Mice treated with these cells showed an 83% survival rate, compared to 33% for controls, and demonstrated improved artery formation and survival.
SourceMorgridge Institute for Research·JournalProceedings of the National Academy of Sciences·DateJul 10, 2017
Scientists have created a comprehensive, high-quality reference set of human induced pluripotent stem cell lines from 301 healthy volunteers. The resource is available for independent research and will help researchers study common genetic variation to put disease variations in context with healthy people.
SourceWellcome Trust Sanger Institute·JournalNature·DateMay 10, 2017
Researchers at Boston University School of Medicine are creating an induced pluripotent stem cell-based library for sickle cell disease, offering a valuable resource for disease modeling and treatment development. The library comprises diverse patient samples, enabling the study of genetic backgrounds and potential therapies.
SourceBoston University School of Medicine·JournalStem Cell Reports·DateJan 19, 2017
A complex of genes regulating epigenetic mechanisms is linked to premenstrual dysphoric disorder (PMDD), a condition affecting 2-5% of women of reproductive age. Dysregulated expression of these genes suggests abnormal cellular response to sex hormones, which may hold hope for improved treatment.
SourceNIH/National Institute of Mental Health·JournalMolecular Psychiatry·DateJan 3, 2017
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Scientists at Tomsk Polytechnic University have developed magnetic stem cells that can target cancer cells with precision and deliver medication directly to the tumor site. The technology uses patient's own magnet-controlled cells, which are not rejected by the immune system and cause less harm.
SourceTomsk Polytechnic University·JournalAdvanced Healthcare Materials·DateDec 28, 2016
Researchers at ETH Zurich have created artificial beta cells that can effectively regulate blood sugar levels. These cells work by measuring glucose concentrations in the blood and producing insulin when necessary, making them a promising solution for diabetes treatment.
The GeroScope algorithm identified 10 substances with potential geroprotector properties, including PD-98059 and NAC. The study suggests that computer modeling can significantly reduce the time and cost of developing new drugs.
SourceMoscow Institute of Physics and Technology·DateDec 6, 2016
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SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
A recent study has found that induced pluripotent stem (iPS) cells derived from patient skin cells may contain faulty mitochondrial DNA mutations, which could undermine their therapeutic value. Screening and checking for mitochondrial DNA mutations is crucial to ensure the quality of iPS cell lines intended for therapeutic use.
Researchers have discovered significant differences in cells derived from dura mater and skin samples across the lifespan, highlighting the importance of considering the cell's original location and donor age. These findings necessitate further exploration into epigenetic patterns in stem cells used for new tissue and organ generation.
Researchers designed a revolutionary high-throughput robotic platform to automate the process of generating patient-specific stem cells, reducing variability and increasing scale. This technology allows for 'clinical trials in a dish' and can identify potential drug metabolism and toxicity issues in human cells before clinical trials.
SourceNew York Stem Cell Foundation·JournalNature Methods·DateAug 3, 2015
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Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Scientists at University of Michigan and University of Texas Southwestern Medical Center discovered microscopic nanotubes facilitating cell-to-cell communication in stem cells. The findings suggest that these structures may play a crucial role in retaining stem cell identities during division.
SourceUniversity of Michigan·JournalNature·DateJul 1, 2015
The New York Stem Cell Foundation has launched the largest-ever stem cell repository, offering over 600 induced pluripotent stem (iPS) cell lines from diverse human subjects. The repository provides a vast resource for scientists to study various diseases, including type 1 diabetes, Parkinson's disease, and multiple sclerosis.
Researchers have developed a new reprogramming factor cocktail that produces high-quality induced pluripotent stem cells with fewer genetic abnormalities. The SNEL combination outperforms existing methods, such as OSKM, in terms of cell quality and efficiency.
SourceWhitehead Institute for Biomedical Research·JournalCell Stem Cell·DateSep 4, 2014
Researchers have developed a method to grow human GI cells from patient tissue in as little as two weeks, creating over 65 cell lines. This breakthrough enables the study of individual patients' underlying problems and can be used to test new treatments.
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Scientists suggest that every town could have a small-scale cultured meat factory, producing sustainable and cruelty-free meat alternatives. The production process involves taking stem cells from cell banks and using them to create minced meat cakes.
SourceCell Press·JournalTrends in Biotechnology·DateMay 20, 2014
Scientists at the University of Washington have successfully created a line of human embryonic stem cells that can develop into various tissues. The new 'naive' cells retain their natural ability to differentiate into all types of human cells without artificial genes, opening up possibilities for regenerative medicine and transplantation.
SourceUniversity of Washington School of Medicine/UW Medicine·JournalProceedings of the National Academy of Sciences·DateMar 13, 2014
Researchers have developed a device that can sort human cells based on their stiffness, which may help doctors diagnose diseases more accurately. The technology uses microfluidic channels and ridges to separate cells into two streams depending on their mechanical properties.
SourceGeorgia Institute of Technology·JournalPLOS ONE·DateOct 16, 2013
NYSCF and PPMI collaborate to develop stem cell lines from patients, enabling researchers to study Parkinson's disease progression. The partnership aims to identify biomarkers and accelerate treatment development.
Experts recommend approaches to standardize quality control, develop cost-effective sharing models, and create large-scale libraries of iPSC lines. These efforts aim to tap into the potential of iPSCs for drug screening, disease modeling, and medical treatments.
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Researchers at the University of Pennsylvania School of Medicine have created a human-cell model of early-disease progression in pancreatic cancer using induced pluripotent stem cells. The study identified biomarkers that could be used for early detection, treatment, and prognosis.
SourceUniversity of Pennsylvania School of Medicine·JournalCell Reports·DateJun 20, 2013
Researchers at Boston Children's Hospital discovered a biomarker, WNT3, that helps pinpoint stem cell lines primed to develop into cells and tissues including pancreas, liver and bladder. This finding could simplify the process of selecting the right cell line for generating specific tissues for study.
SourceBoston Children's Hospital·JournalStem Cell Reports·DateJun 4, 2013
Scientists have developed a safety test for human induced pluripotent stem cells (iPS) that can identify unwanted cells forming tumours and assess cell stability. The breakthrough could improve the quality of iPS cells and lead to safer cell therapies.
SourceCSIRO Australia·JournalStem Cells·DateJun 3, 2013
A collaborative study reveals how modifications in key epigenetic markers influence human embryonic stem cells as they differentiate into specialized cells. The findings provide insights into processes during early human development and tissue formation.
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DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.
New York Stem Cell Foundation researchers have developed a quantitative protocol to consistently harvest early-reprogrammed cells, resulting in standardized iPS cell lines. This method enables the derivation of 228 individual iPS cell lines, which can be compared to one another for use in drug screens and cell therapies.
SourceNew York Stem Cell Foundation·JournalPLOS ONE·DateApr 3, 2013
Researchers at Baylor College of Medicine discovered a positive feedback loop between Notch and TGF beta proteins that maintains basal cell population in the prostate. Disrupting this loop may contribute to prostate cancer initiation.
SourceBaylor College of Medicine·JournalCell Stem Cell·DateNov 1, 2012
A new human embryonic stem cell line has been developed to aid research on Charcot-Marie-Tooth disease, a common inherited neurological disorder. The line, derived from a donated embryo carrying the gene defect responsible for CMT, is now available for federally-funded research.
SourceMichigan Medicine - University of Michigan·DateApr 25, 2012
A small number of cells in the embryo are enough to form the outer layer of pumping heart muscle in an adult zebrafish. The researchers discovered that only eight single cells contributed to forming a major type of heart muscle, and just one or two cells could create up to 70% of the entire ventricular surface.
SourceDuke University Medical Center·JournalNature·DateApr 25, 2012
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Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Researchers at King's College London have made a breakthrough in developing xeno-free human embryonic stem cell lines that are suitable for public benefit. The lines will be grown and processed by the UKSCB to provide stem cell stocks for clinical research and treatment.
A study published in Cell Stem Cell reveals that adjusting the levels of reprogramming factors can significantly impact the quality and fidelity of induced pluripotent stem (iPS) cells. This finding explains the variability in iPS cell quality reported in recent studies, which has sparked debate about their therapeutic potential.
SourceWhitehead Institute for Biomedical Research·JournalCell Stem Cell·DateDec 1, 2011
Researchers found that newly derived human embryonic stem cell lines have a better molecular signature than established lines, indicating higher quality and potentially better performance in disease modeling. The study suggests that maintaining the original state of X chromosome inactivation could be crucial for achieving optimal results.
SourceUniversity of California - Los Angeles Health Sciences·JournalHuman Molecular Genetics·DateNov 30, 2011
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Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
A Scripps Research team has overcome a major purification problem for stem cells, enabling more reliable and safe treatments. The new method uses lectin arrays to separate stem cells from other cell types, promising significant cost savings and reliability improvements.
SourceScripps Research Institute·JournalCell Research·DateSep 8, 2011
Researchers have successfully manipulated targeted genes in human embryonic and induced pluripotent stem cells using zinc finger nucleases and transcription activator like effector nucleases. This precision enables the study of genetic diseases and the development of disease-modifying drugs.
SourceWhitehead Institute for Biomedical Research·JournalCell·DateJul 14, 2011
A new study by researchers at Stanford University School of Medicine and others found that curtailing human embryonic stem cell research would negatively impact induced pluripotent stem cell research. The study refutes the idea that iPS cells can replace embryonic stem cells in research.
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A new study by University of Michigan researchers suggests that banning federal funding for human embryonic stem cell research would have disastrous consequences on the use of induced pluripotent stem cells (iPS cells). The two cell types are complementary and interdependent research tools, and their use has become intertwined. As a re...
SourceUniversity of Michigan·JournalCell·DateJun 9, 2011