Articles tagged with Blastemas
Researchers have discovered that jellyfish use stem-like proliferative cells to form a blastema, which helps regenerate functional tissue across the missing appendage. This study provides insight into the mechanism of blastema formation and may improve our own regenerative abilities.
Researchers discovered ERK signalling is a crucial switch between scarring and regeneration, with prolonged activation promoting regenerative success. Modulating ERK activity could potentially stimulate regeneration in clinical settings.
Researchers at the University of Tsukuba found that the Newtic1 protein plays a crucial role in limb regeneration by secreting TGFβ1 growth factors. This discovery sheds light on the regenerative abilities of adult newts and their potential as a model for regenerative medicine.
Researchers at the University of Tsukuba and the University of Dayton discovered a novel gene, Newtic1, expressed in red blood cells that may contribute to adult newt limb regeneration. The study found that Newtic1-expressing erythrocytes play a crucial role in releasing growth factors into regenerating blood vessels.
Researchers at Tokyo Institute of Technology identified fgf20a and fgf3/10a as major fibroblast growth factor ligands involved in fin regeneration. Fgf signalling acts directly on fin ray mesenchyme to form a blastema, promoting cell proliferation and tissue recovery.
Researchers at UCI found that cells from a transplanted limb acquire the molecular 'fingerprint' of their new location, allowing them to transform into cells with the signature of the region they're grafted onto. This ability, called positional plasticity, has implications for regenerative therapies and cancer biology.
A UK research team discovered a new molecular cue that promotes limb regeneration in newts, which could help guide the field of regenerative medicine. The finding was recognized with the 2008 AAAS Newcomb Cleveland Prize.