Articles tagged with Corneal Regeneration
Scientists have identified key corneal neurons involved in sensitivity and developed an experimental model to study nerve regeneration. The Ocular Neurobiology laboratory is participating in the RESTORE VISION project, which aims to improve eye health and quality of life for those affected by rare eye diseases.
A pioneering study published in The American Journal of Pathology reveals the cytoprotective and proregenerative effects of neuropeptide α-MSH in promoting corneal healing after eye injury. The treatment has shown impressive therapeutic potential in reducing the need for corneal transplants.
The World Mitochondria Society will host Targeting Mitochondria 2023, a conference featuring sessions on innovations such as mitochondria in space and exosome-based mitochondrial medicine. The event aims to take clinical translation of mitochondrial therapies to a new level.
A mouse study found that proteins made by stem cells in mice with dry eye disease may be new targets for treating injuries to the cornea. The researchers identified a key gene, SPARC, that is activated in response to injury in dry eye disease and found higher levels of its protein are associated with better healing.
Researchers at Brigham and Women's Hospital identified Basal Cell Adhesion Molecule (BCAM) as a key population of proliferative cells involved in corneal regeneration. BCAM plays a crucial role in mediating corneal differentiation, which could lead to future medical therapies for corneal disease.
A new study provides evidence supporting the involvement of aquaporins in corneal cell proliferation and nerve regeneration, suggesting AQP5 induction as a potential therapy to accelerate corneal defect resurfacing. The study found that AQP5 deficiency can slow down corneal epithelial repair, but its specific mechanism remained unclear.
Researchers at Wayne State University have discovered that dendritic cells play a crucial role in guiding sensory nerve regeneration after wounding, but their interactions are disrupted in diabetic corneas. The study found that applying exogenous CNTF and its soluble receptor CNTFR-alpha can partially reverse the adverse effects of dia...
The University of Pittsburgh will lead a multidisciplinary consortium to explore strategies for whole-eye transplantation, with the goal of restoring vision in patients with traumatic or degenerative eye damage. The project aims to overcome challenges related to immune rejection and optic nerve regeneration.