A new study reveals that four living amphibian clades, including the dominant Plethodontidae family of lungless salamanders, develop lungs as embryos but lose them as adults. This finding sheds light on the evolution of lung loss over millions of years and suggests that losing lungs may have enabled their remarkable evolutionary success.
Ann Beliën, CEO and Founder of Rejuvenate Biomed, will present her latest research on platform-based clinical development in aging. Her company has evolved from a discovery company to a clinic stage company under her leadership with over 20 years of experience in drug development.
Oceanographers have discovered substantial subsurface phytoplankton layers deep beneath the eastern part of the Great Australian Bight, supporting rich marine biodiversity. This finding explains how the region's productivity survives even when surface phytoplankton blooms disappear during certain upwelling seasons.
Dr. David Buck, a University of Houston professor, has dedicated his career to healing homelessness and fixing the broken aid industry. He founded Healthcare for the Homeless Houston and Patient Care Intervention Center to provide comprehensive care and collaborative partnerships.
A randomized clinical trial found that GlyNAC supplementation improves age-associated defects in older humans, including oxidative stress and mitochondrial dysfunction. This led to improvements in muscle strength, gait speed, exercise capacity, and other health outcomes, showing promise for promoting healthy aging.
Researchers found large impacts can fracture a planet's crust, introducing porosity that increases its potential for life. This discovery has implications for early Earth and Mars, suggesting life could have survived in pore spaces during intense impact periods.
A study published in Early Education and Development journal found that preschoolers with stronger vocabulary skills at the start of the year display more positive engagement with teachers and peers. The researchers also discovered that inhibitory control is crucial for classroom engagement and learning.
A study by Japanese researchers from Fujita Health University sheds light on the molecular mechanisms of contact dermatitis, revealing that neutrophil extracellular traps play a key role in the condition. The team's findings suggest that inhibiting NET formation could be a new therapeutic strategy for treating contact dermatitis.
A new paper outlines principles for reducing power imbalances in biological fieldwork, including procedures for permitting and licensing developed at the University of Kansas. The guidelines aim to ensure safety, legal, and ethical conduct, prioritizing communication and transparency in fieldwork planning.
Researchers at Cedars-Sinai Medical Center have developed a new method to identify which human gut microbes contribute to inflammatory diseases. By analyzing protein levels in blood serum, the team discovered specific bacteria that trigger immune activation and inflammation.
A collaborative effort by UT Southwestern computational biologist Qian Cong and molecular biologists at the University of London elucidated the 3D structure of the Type IV secretion system (T4SS) complex. The study's findings provide a blueprint for designing drugs that can slow the development of antibiotic resistance.
Researchers from the University of Cambridge's CSER highlight the need for improved surveillance and public education to mitigate the impact of volcanic eruptions. The risk of a magnitude seven explosion in the next 100 years is one-in-six, with potential consequences including abrupt climate change and collapse of civilizations.
Olga Boukrina's five-year grant funds research on neurobehavioral reading intervention with potential to promote post-stroke plasticity. The study aims to develop an fMRI neurofeedback-based approach to improve reading recovery in stroke survivors.
A comprehensive review of water quality trading programs worldwide reveals that agricultural production remains largely unregulated, hindering their effectiveness. The authors suggest that nudging political will and creating regulatory drivers can help evolve water quality trading into a cost-effective pollution control instrument.
Researchers have discovered a molecule that can suppress the development of kidney fibrosis, a condition leading to kidney failure and devastating consequences. The breakthrough could lead to the development of new drug treatments for millions of people affected by chronic kidney disease.
A new study published in PLOS ONE explores the relationship between preterm birth and educational attainment in U.K. children. The research found that children born before 32 weeks had higher rates of poor school attainment, but only those born very preterm remained at risk by the end of secondary school.
Researchers at Brown University achieved a zero-field superconducting diode effect in small-twist-angle trilayer graphene, enabling lossless current flow. The discovery confirms theoretical assumptions and paves the way for future quantum electronics applications.
Researchers tested a new needle ablation technique called SERF to treat ventricular tachycardia in patients who had not responded to other treatments. The study found that 31 of 32 patients experienced eliminated clinical ventricular tachycardia, with device therapies reduced by 89% during follow-up.
A new study led by Flinders University found that a mental impairment plea can lead to negative effects on a person's social standing and even civil rights. The research suggests that such pleas may be perceived as increasing dangerousness, resulting in exclusionary policies and treatment.
A study found that combining a height-adjustable desk with an education programme, such as SMART Work and Life, can significantly reduce sitting time in the workplace. Participants using both the programme and a desk spent over an hour more time on their feet per day compared to those receiving the programme alone.
Research shows that exposure to commonly used insecticides can profoundly impair honeybees' visually guided behavior, crucial for flight and survival. The study found that pesticide-exposed bees have impaired optomotor responses, with increased asymmetry in left and right turns.
A study published in Frontiers in Immunology found that Japanese herbal medicine DKT reduces colitis severity by preventing gut bacteria loss and increasing immune cells. It restores Lactobacillus levels and promotes type 3 innate lymphoid cells, alleviating inflammatory responses.
Researchers developed a label-free Raman spectroscopy approach with enhanced sensitivity and speed, allowing for non-invasive imaging of biological samples. The new CARS microscopy system can acquire microscopic images and identify biomolecules with unprecedented resolution and speed.
Amy Rowat's research on cultured meat has made significant progress, with a new study showing the potential for efficient production methods. By using gelatin and food-grade enzymes to create edible microcarriers, Rowat's team is paving the way for lab-grown meat alternatives.
Researchers found a 20% decrease in coronary artery dilation and reduced myocardial flow reserve in patients with prior COVID-19 infection. This may lead to poor prognosis and higher risk of adverse cardiovascular events.
Scientists have developed Live-seq, an innovative approach that keeps cells alive during RNA extraction for further study. This technique uses FluidFM to manipulate tiny volumes of fluids in a sample under the microscope, allowing for the insertion and extraction of mRNA from single cells without killing them.
Researchers developed a method combining musical tests with EEG measurement to detect cognitive decline in old age. The study tested 50 elderly people who scored low on the mini-mental test, showing promising results in detecting mental deterioration.
A new study found that 72% of methylmercury concentration variance in largemouth bass can be explained by land cover types. Monitoring efforts should focus on ecoregions with increased sensitivity to atmospheric mercury deposition.
The development of LEO mega constellations has significantly impacted human scientific progress in communication, navigation, and remote sensing. However, unrestrained deployment poses a threat to spacecraft safety and space environment stability, requiring rational surveillance and governance mechanisms.
A new analysis suggests that Nutri-Score labeling can help consumers make healthier food decisions by countering misleading sugar claims. The study found that participants were more likely to perceive unhealthy foods as healthier when a Nutri-Score was absent, but the presence of this label reduced misconceptions.
A Texas A&M AgriLife Research project investigates the ages-long interaction between parasitic lice and mammal species, including humans. The researchers aim to answer why various louse species parasitize specific hosts and what makes these species good hosts.
A large international team has reexamined the Saccorhytus microfossil and determined that it is actually a protostome, not a deuterostome as previously believed. This finding contradicts current understanding of animal evolution, suggesting a significant gap in the fossil record.
A recent paper by Darren Grant found favoritism in order assignment in various contests, including Texas and West Virginia primary elections. The author applied statistical methods to detect this behavior, which was often overlooked despite its significant impact on outcomes.
Researchers developed a new anti-cancer drug LP-182 that simultaneously targets two molecular signaling pathways responsible for cancer growth. The drug is absorbed through the gut's lymphatic system, maintaining optimal therapeutic levels over time.
A new study presents the first data-driven sex-specific model of pediatric cranial bone development, providing a quantitative normative reference for local cranial bone development during the first ten years of life. The model improves current understanding and clinical diagnoses of cranial development disorders.
NTU Singapore has launched the Algorand Centre of Excellence at NTU (ACE@NTU), a new research and education centre focused on developing and advancing blockchain technologies. The centre aims to become the nexus for blockchain education and research in Singapore and the region.
Scientists at the University of Chicago discover a method to increase lithium selectivity in olivine iron phosphate using electrochemical intercalation. Seeding electrodes with lithium ions can repel unwanted elements, improving the efficiency of lithium extraction from dilute water resources.
Researchers at the University of Cambridge have developed ultra-thin, flexible devices that can convert sunlight into fuels as efficiently as plant leaves. The devices, inspired by photosynthesis, could be used on polluted waterways, in ports or even at sea to reduce reliance on fossil fuels.
A proof-of-concept study developed three machine learning models to predict posttreatment recurrence in early-stage hepatocellular carcinoma patients. The models achieved high accuracy using imaging data alone, while combining clinical data did not significantly improve performance.
A recent study found that microplastics in agricultural soils can cause a decrease in germination rate and changes to seed production, which could have negative consequences for food production. The presence of microplastics also alters soil characteristics such as its structure and microbial communities.
Researchers used a three-dimensional climate model to recreate Earth's history and found that changing continents significantly increased ocean oxygen levels. This new study reveals the previously underestimated role of plate tectonics in shaping ocean biodiversity.
Research team analyzed hundreds of new fossil specimens to clarify the anatomy and evolutionary affinity of Saccorhytus. They found evidence supporting its classification as an ecdysozoan, including a terminal mouth, cuticle integument, and radially arranged circumoral structures common to Cambrian and extant ecdysozoans.
Research finds Palmer amaranth populations in Arkansas and two Southern states are resistant to S-metolachlor, a Group 15 herbicide. Resistant populations require more herbicide to control seedling emergence, but remain susceptible to other VLCFA inhibitors like dimethenamid-P and pyroxasulfone.
Scientists at OIST Graduate University discovered the neural circuitry that enables juvenile zebra finches to learn songs through social interaction with a tutor. The locus coeruleus-caudomedial nidopallium circuit plays a crucial role in attention and arousal, guiding the bird's focus on the tutor's song.
A team of researchers from Princeton University and the Broad Institute created a fast, accurate, and equipment-free diagnostic test for COVID-19. The test uses CRISPR technology to detect SARS-CoV-2 variants and can be performed at home without special equipment, improving sensitivity and specificity compared to existing tests.
Research has focused on understanding and resolving air-sensitivity in sodium-based layered oxide cathode materials. Strategies include surface coating, washing, and element substitution to improve air stability.
A new study found that countries with greater universal health coverage had smaller declines in childhood immunization coverage during the COVID-19 pandemic. Countries with a high UHC index had an average childhood immunization coverage rate of 92.7% compared to 86.2% in those with lower UHC indices.
The study found a 31% decline in sleep medication use between 2013 and 2018, with the strongest decrease in FDA-approved medications. Behavioral treatments for insomnia are increasingly encouraged due to their effectiveness and reduced risk of adverse outcomes.
Long-term research at LTER sites reveals climate change effects on ecosystems, including altered productivity and biodiversity. Coastal ecosystems, such as kelp forests and coral reefs, are particularly vulnerable to changes in water temperature and storms.
A research team has been awarded $10 million to develop a collaborative care model to prevent Alzheimer's disease and other dementias among delirium survivors. The study aims to improve cognitive recovery and quality of life for patients after emergency surgery.
A team of researchers from Australian National University developed a mathematical model to simulate the impact of prolonged exposure to zero gravity on the cardiovascular system. The model assesses the risk of fainting or medical emergencies when stepping out of a spacecraft on Mars, providing crucial insight for human mission planning.
Researchers at Queen Mary University of London have found that increasing the blood level at which faecal blood testing triggers a colonoscopy invitation can reduce lives lost from bowel cancer. This approach is more effective than changing the gap between screening invitations.
A new gene variant, MFGE8, has been discovered that protects against coronary heart disease, with carriers experiencing a one-fifth lower risk. The variant is located in the MFGE8 gene and inhibits the function of lactadherin protein, which affects arterial stiffness.
A new paper introduces free machine translation services to convert scientific papers into multiple languages, promoting accessibility and global collaboration. Researchers at UC Berkeley developed these tools to address the dominance of English in scientific research, enabling scientists worldwide to share their work.
Researchers used artificial intelligence to demonstrate the correlation between cytoskeleton organisation and nuclear position in eukaryotic cells. The study successfully predicted the presence and location of nuclei in over 8,000 cells with high accuracy, transforming the way scientists approach complex biological systems.
The expert panel identified actionable and inclusive solutions to accelerate the development of novel therapies for Alzheimer’s disease. The panel suggested strategies such as increasing diverse population representation, addressing logistical, financial, and trust barriers to participate in trials.
Researchers developed a novel method to monitor oxygen levels in the placenta using optical measurements and ultrasound, providing insights into its function and structure. The device showed promise in detecting placental dysfunction and differentiating between healthy and diseased placentas.
A randomized controlled trial found that virtual museum visits significantly improved the health of seniors stuck at home, reducing social isolation and improving well-being, quality of life, and frailty. The study recruited 106 participants aged 65 and older who attended guided tours online once a week for three months.
The project empowers Indigenous youth to create films about locally available foods and other concerns, raising awareness of nutritional deficiencies and gender discriminatory norms. The initiative aims to improve dietary diversity and promote transformative change through self-expression and participation.
Engineers developed a machine learning algorithm that can detect and correct wide variety of errors in real time, learning from other machines' experiences. The algorithm enables 'driverless' printers to work for multiple parts, materials, and printing conditions.