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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Which came first: The sponge or the comb jelly? HHMI scientists weigh in

Researchers at the Howard Hughes Medical Institute used a new method to determine which animal evolved first, finding support for the sponge hypothesis. The study suggests that sponges are rooted at the base of the animal tree of life, contrary to previous theories suggesting comb jelly ancestors.

Gene related to human kidney disease linked to touch in sea anemones

Researchers have discovered a common gene linked to human kidney disease is also present in sea anemones, allowing their hair cells to detect water movement. This finding suggests an evolutionarily ancient role for the gene in sensing fluid movement, predating the common ancestor of mammals and sea anemones.

Scientists recreate mouse from gene older than animal life

An international team of researchers successfully created a mouse using genetic tools from a unicellular organism, challenging the notion that these genes evolved exclusively within animals. The study uses ancient genetic tools to reprogram mouse cells into pluripotent stem cells.

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Megadiverse flowering plant family on isolated islands

Researchers discovered a massive number of evolutionary events in the Asteraceae family on remote islands, resulting from rapid speciation over short time periods. The findings confirm that larger, isolated islands harbor unique species and highlight the importance of protecting this diverse group of plants.

Distant relatedness in biobanks harnessed to identify undiagnosed genetic disease

A new method using shared segments within the genome has identified undiagnosed cases of Long QT syndrome, a rare disorder that can lead to abnormal heart rhythms and sudden cardiac death. The approach was developed by researchers at Vanderbilt University Medical Center and applied to a DNA biobank to detect carriers of rare disease-ca...

New evidence suggests ancient origin of the "common enemy effect"

A recent study published in PLOS ONE found that bonobos, known for their nonviolence, show a moderated version of the common enemy effect when faced with threats from other groups. The researchers suggest that this behavior may have emerged several million years ago, before human and chimpanzee lineages diverged.

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Echidnapus identified from an ‘Age of Monotremes’

Australian researchers have identified a new species of ancient 'echidnapus', which exhibits platypus-like anatomy alongside echidna-like features. The discovery sheds light on the evolutionary history of monotremes, revealing six different egg-laying mammals living together in the same area over 100 million years ago.

Orangutan treats wound with pain-relieving plant

A male Sumatran orangutan applied sap from a climbing plant with anti-inflammatory and pain-relieving properties to a facial wound, closing it within five days. This self-medication behavior may have originated in a common ancestor shared by humans and orangutans.

Anemonefish are better taxonomists than humans

Researchers at OIST found that anemonefish can identify specific lineages of giant sea anemones, revealing two cryptic species within the bubble-tip sea anemone. The study provides new insights into marine biodiversity and highlights the remarkable abilities of these fish in distinguishing between different sea anemone groups.

Cell types in the eye have ancient evolutionary origins

Researchers found that most cell types in the retina are ancient and conserved across species, indicating a complex retina in the last common ancestor of all mammals. The study suggests that some cell types have been remodeled or repurposed over time to adapt to different visual needs.

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Looking for ‘LUCA’ and the timing of cellular evolution

Researchers use molecular dating approach to estimate moment of LUCA's split into bacteria and archaea, as well as eukaryotes' emergence. The study reveals archaea are younger than previously thought, with some potentially living hidden on Earth.

Enlighten me

Researchers at Kyoto University discovered that liverwort Marchantia polymorpha uses gibberellin precursors to produce a signaling molecule aiding survival under shaded conditions. This metabolic pathway inheritance provides insight into the evolution of plant hormone responses.

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New study reveals reptiles’ spontaneous association between vision and hearing

A new study reveals that reptiles demonstrate spontaneous associations between visual and auditory information, including tortoises associating low sounds with large shapes and high pitch sounds with small shapes. This discovery shows how brains are prepared to predict visuo-acoustic correspondences likely to occur in the natural world.

Butterflies and moths share ancient ‘blocks’ of DNA

Researchers have identified 30 basic units of 'synteny' that exist in all butterflies and moths, dating back to their common ancestor with caddisflies. This study improves understanding of chromosome evolution in Lepidoptera and may provide insights into other animal or plant groups.

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Remains of an extinct world of organisms discovered

Researchers have uncovered previously unknown biomarker signatures pointing to a vast array of ancient organisms that thrived on Earth about a billion years ago. These 'protosteroids' offer an unprecedented glimpse into the conditions surrounding the emergence of complex life.

Mapping the genetic history of French Canadians through space and time

A new study maps French Canadian populations using a unique dataset of over five million records spanning 400 years, revealing the complex relationship between human migration and genetic variation. The research shows that the genetic structure of French Canadians is encoded within its genealogy.

Rigol DP832 Triple-Output Bench Power Supply

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What did the earliest animals look like?

Researchers use chromosome structure to determine that comb jellies were the first lineage to branch off from the animal tree, followed by sponges. This finding sheds light on how animals arose and evolved into the diverse species we see today.

Sony Alpha a7 IV (Body Only)

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Vocal communication originated over 400 million years ago

A study published by the University of Zurich has found that vocal communication in vertebrates has a common and ancient evolutionary origin, dating back to around 407 million years ago. The research used vocal recordings and contextual behavioral information from 53 species across four major clades of land vertebrates.

Revealing the genome of the common ancestor of all mammals

Researchers reconstructed the genome organization of the earliest common ancestor of all mammals using high-quality genome sequences from 32 living species. The study reveals that the mammal ancestor had 19 autosomal chromosomes and conserved gene blocks across modern mammalian genomes.

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Animals evolved the ability to gallop 472 million years ago

Scientists discovered that animals likely evolved asymmetric gaits 472 million years ago, with evidence of crutching and bounding in ancient fish and crocodiles. The study suggests that many modern species have lost this ability due to evolution or size constraints.

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University of Oxford researchers create largest ever human family tree

Researchers from the University of Oxford's Big Data Institute have created a single genealogy tracing the ancestry of all humans, combining genome sequences from eight databases and 3,609 individual genomes. The study successfully recaptured key events in human evolutionary history, including migration out of Africa.

Snakes diversified explosively after the dinosaurs were wiped out

A study found that snakes rapidly diversified their diets following the K-Pg mass extinction event, incorporating birds, fish, and small mammals into their diet. This diversification was triggered by ecological opportunities presented by the extinction, with some lineages experiencing further bursts of adaptive evolution.

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More ancestral enzyme

The study reports the crystal structures of aconitase X enzymes from bacteria and archaea, providing novel insights into their catalytic mechanisms. The findings suggest that ancestral active sites in aconitase superfamily are conserved across different species.

Penguin hemoglobin evolved to meet oxygen demands of diving

Researchers found that penguin hemoglobin captured oxygen more readily than the version in non-diving ancestors, allowing for better oxygen capture and release. The stronger affinity also helped tissues starved for oxygen by acting as a 'stronger magnet' to pull more oxygen from the lungs.

Algal genome provides insights into first land plants

The Penium margaritaceum genome provides insights into the origins of land plants by revealing footprints of adaptations for UV radiation protection and cell wall structure. The genome contains genes involved in regulatory systems, hormone signaling, and mucilage production, which are essential for structural support.

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How Darwin's finches diversify

A study on Darwin's finches reveals two pathways of species generation and diversification driven by selective mating based on body and beak size. The authors note that hybridization between similar lineages can drive speciation, highlighting the importance of conservation of diverse environmental conditions.

New 13-million-year-old infant skull sheds light on ape ancestry

A newly discovered infant ape skull from 13 million years ago provides insights into the evolution of human ancestors. The fossil, nicknamed Alesi, reveals a brain cavity, inner ears, and unerupted teeth that indicate it belonged to a new species, Nyanzapithecus alesi.

Parasite revealed: New insights into dicyemida

Researchers at OIST Graduate University have decisively classified Dicyemida, a microscopic parasite in cephalopods, as part of the Spiralia clade and closest to Orthonectida. This classification sheds new light on the evolutionary history of Spiralia and the process of evolution.

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Bag-like sea creature was humans' oldest known ancestor

A microscopic, bag-like sea creature called Saccorhytus, discovered in China, is believed to be the earliest known step on an evolutionary path that led to humans. Its primitive features, including a large mouth and absence of an anus, have provided new insights into human evolution.

Tracing the ancestry of dung beetles

Researchers have discovered that dung beetles evolved from a single common ancestor, with the onthophagines and oniticellines tribes making up half of the world's dung beetle fauna. These beetles play a crucial role in ecosystems by recycling nutrients and reducing parasites.

'Virtual fossil' reveals last common ancestor of humans and Neanderthals

Scientists recreated the skull of the last common ancestor of Homo sapiens and Neanderthals by applying digital methods and statistical techniques. The 'virtual fossil' reveals that this ancestral population likely originated in Africa and had early hallmarks of both species, with a split timeline of around 700,000 years ago.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

A new primate species at the root of the tree of extant hominoids

Researchers describe a new genus and species, Pliobates cataloniae, with characteristics similar to extant hominoids, overturning previous theories on gibbon origins. The fossil find provides clues about the origin of extant gibbons and their evolutionary relationships.

Shouldering the burden of evolution

Researchers at UC San Francisco show that early humans' tool use led to changes in their shoulders, which helped the emergence of human-specific traits like high-speed throwing. The study's findings suggest that the common ancestor of modern humans and African apes looked more like a chimp or gorilla.

Humans' ancestors had tentacles

Researchers found evidence supporting the idea that the last common bilaterian ancestor had tentacular appendages, a concept favored by the Russian zoological school. This discovery sheds light on the evolution of chordate animals and could help refine the classification system.

New insights into origins of the world's languages

A new study by Berkeley linguists provides evidence that the 'Indo-European' language family originated 5,500 - 6,500 years ago, supporting the 'steppe hypothesis'. The study examined over 200 sets of words from living and dead languages, concluding that divergence began around 6,500 years ago.

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Texas Tech biologist leads group that mapped crocodilian genomes

A Texas Tech University biologist led a team of over 50 scientists in mapping the genomes of three crocodilians, including a crocodile, alligator, and gharial. The research reveals that crocodilian genomes change very slowly compared to birds, with an estimated 93% identical DNA across their genomes.

Tooth loss in birds occurred about 116 million years ago

A research team has found that tooth loss in birds occurred convergently with turtles and multiple mammalian lineages about 116 million years ago. The study used degraded remnants of tooth genes to determine when birds lost their teeth, suggesting a single loss of mineralized teeth in the common ancestor of all modern birds.

Study: No known hominin is ancestor of Neanderthals and modern humans

A recent study using dental fossils suggests that the common ancestor of Neanderthals and modern humans diverged nearly 1 million years ago, contradicting previous molecular evidence. The researchers found no known hominin species matches the expected dental morphology of the last common ancestor.

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