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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Jaws hold crucial knowledge on the fate of sharks

A study of historical tiger shark jaws reveals a local southeastern Australian population has been extirpated due to shark control programs, emphasizing the need for regional management and conservation. Genetic diversity drives future evolution, and its loss can lead to reduced adaptability to environmental changes.

Scientists create viable, reproducing yeast-cyanobacterial hybrids

Researchers at the University of Illinois have successfully engineered artificial photosynthetic life-forms through endosymbiosis between cyanobacteria and yeast. The engineered chimera can survive and reproduce under optimal conditions, shedding light on the evolutionary origins of eukaryotic cells.

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Finding new weapons in nature's battlesites

A research team from the Max Planck Institute for Terrestrial Microbiology has identified 1,000 biosynthetic gene clusters, over half of which are previously unknown. These natural products have been found to be eukaryotic proteasome inhibitors that suppress the immune system of insects, as well as other virulence factors.

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Bonds from the past: A journey through the history of protein synthesis

Researchers studied peptide bond formation between tRNA molecules and a ribosomal RNA segment, revealing the potential for minihelices to bind to the primordial peptidyl transferase center. The study suggests that functional interactions between tRNA and PTC could have been 'revised' in evolution.

Genes can affect our nutrient tolerance

A study found that small genetic variations impact an organism's ability to utilize energy from various nutrients. Researchers identified several genes contributing to sugar tolerance in fruit flies, which are also present in humans and linked to obesity and type 2 diabetes.

Scientists resurrect ancient enzymes to improve photosynthesis

Researchers developed a computational technique to predict favorable gene sequences that make Rubisco, a key plant enzyme for photosynthesis. The study found promise for developing faster and more efficient Rubisco enzymes to increase crop yields and adapt to hot, dry future conditions.

Extreme genetic drift in the Maniq hunter-gatherers of southern Thailand

A recent study on the Maniq population found they exhibit high levels of genetic differentiation, similar to other isolated populations. The researchers also discovered that the Maniq retain a unique hunter-gatherer lifestyle and Hòabìnhian-related ancestry, setting them apart from other Southeast Asian groups.

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Scientists crack egg forging evolutionary puzzle

A recent study by researchers from the University of Cambridge and Boston University has made a major breakthrough in understanding how cuckoo finches mimic eggs of multiple host species. The team found that female cuckoo finches inherit their egg-mimicry abilities from their mothers, allowing them to exploit different host species. Ho...

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Tiny jumping genes fingered as culprit in rise of antibiotic resistance

Biomedical engineers at Duke University have discovered a physical mechanism that causes high doses of antibiotics to promote the spread of antibiotic resistance between bacteria. The culprit is an overabundance of 'jumping genes,' called transposons, which carry genetic instructions for resistance from cell's source code to plasmids.

Fitness needs the right timing

The study found that cryptochromes are conserved across various green organisms, influencing cell structures responsible for photosynthesis. The researchers discovered that a specific cryptochrome can actually lead to increased growth despite appearing darker green due to denser packed cell membranes.

Are egg cells in aging primates protected from mutations?

Researchers found that mutation frequencies in mitochondrial DNA of developing egg cells are lower and increase less with age compared to non-reproductive cells. This suggests a protective mechanism may keep reproductive cells relatively stable, potentially related to human propensity to reproduce at later ages.

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Fruit flies adapt activity to “white nights”

Research team at University of Münster finds that a specific gene variant allows fruit flies to synchronize their circadian rhythm with temperature cycles under constant light. This adaptation enables better mating opportunities and increases the allele's evolutionary success.

Striking lane-like patterns found in bacteria populations

Researchers from OIST found that Escherichia coli bacteria form lanes of genetically similar individuals when constrained to a channel, aligning parallel to the barriers. The study, published in PNAS, used microfluidic platforms and simulations to observe population dynamics over several generations.

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One bird's joy is another bird's sorrow

Researchers found that female Faeder variants produce fewer offspring, but this disadvantage helps their males, who benefit from their rarity and obtain more matings. The contrasting effect of the variant contributes to its persistence over time.

How new bird species arise

A study reveals that new bird species arise in lowland habitats before moving higher into mountainous areas, where genetic differences accumulate. The research suggests that climate fluctuations, particularly during the Pleistocene era, contributed to the evolution of these high-altitude populations.

An ‘oracle’ for predicting the evolution of gene regulation

A new mathematical framework has been created to study fitness landscapes of regulatory DNA, enabling the prediction of gene expression changes. The framework uses a neural network model trained on millions of experimental measurements to decipher the evolutionary past and future of non-coding sequences.

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Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

An introgression strategy to expand genetic variation

Scientists create novel germplasm by introgressing B. rapa genome into B. juncea and demonstrate increased genetic diversity and phenotypic variation among the introgression lines. This strategy provides a new method to expand genetic variation in Brassica species.

A new molecular family tree of grasses

A new molecular study of grasses reveals a clear picture of their evolutionary relationships, shedding light on the evolution of C4 photosynthesis involved in heat and drought tolerance. The research provides evidence that this type of photosynthesis evolved independently multiple times within different grass lineages.

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Bacteria genes gave ancient plants traits to colonize land

Researchers found that hundreds of bacteria genes were integrated into ancient plants, granting them desirable traits for land colonization. The study suggests horizontal gene transfer played a significant role in land-plant evolution, allowing plants to adapt rapidly to new environments.

Harmless or deadly? New study examines evolution of E. coli bacteria

Research suggests that genetic material from E. coli bacteria in farm animals may contribute to the evolution of deadly pandemic strains. The study found that ColV plasmids in pigs, cattle, and chickens can increase the likelihood of antimicrobial resistance and extra-intestinal infections in humans.

Sex pays off

Research shows that asexual reproduction in stick insects, such as parthenogenesis, reduces genetic variability and slows down adaptation to environmental changes. This negatively impacts the speed of adaptation and genetic diversity in these insects.

University of Oxford researchers create largest ever human family tree

Researchers from the University of Oxford's Big Data Institute have created a single genealogy tracing the ancestry of all humans, combining genome sequences from eight databases and 3,609 individual genomes. The study successfully recaptured key events in human evolutionary history, including migration out of Africa.

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Researchers discover when pollen comes of age

A new study from the University of Georgia reveals that pollen begins expressing its own genome at a specific point in its life cycle. This discovery has significant implications for plant breeding, as it allows researchers to predict how plant species adapt to environmental changes and potentially speed up crop development.

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Getting a step ahead of TB’s drug resistance evolution

Researchers studied microorganisms, including TB bacteria, to understand how genetic mutations drive adaptation and resistance. They found that certain types of mutations are more common than others, and this imbalance can help scientists predict which mutations will lead to drug resistance.

Driving conservation efforts with DNA data

Using ancient and historical DNA can assess population genetic patterns and inform conservation actions. The study reveals that a/hDNA can be compared with contemporary data to set baselines for intra-species genetic diversity and estimate changes in effective population size.

Carter Awarded $1.5 million for Origin of Life Research

Researchers led by Charles Carter will investigate how critical molecules interacted and evolved together, leading to the emergence of life on Earth billions of years ago. They aim to characterize an ancestral alphabet and establish how it grew into the twenty-letter coding alphabet used in genes.

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AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Three Exeter researchers win Discovery Fellowships

Three University of Exeter researchers Dr Jasmine Ono, Dr Luis Yanez Guerra and Dr Jane Usher have been awarded BBSRC Discovery Fellowships for innovative research in biotechnology and biological sciences. They will focus on improving scientific knowledge to develop better treatments for human fungal pathogens and understanding the ori...

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

New study unlocks mystery origin of iconic Aussie snakes

A research team led by University of Adelaide found tangible evidence that Australian elapids arrived by sea rather than land. The study analyzed genomes of two Australian elapids and compared them to marine and semi-marine elapid sea snakes, finding similarities with marine life genes.

Reconstructing the chromosomes of the earliest animals on Earth

A recent study found that many marine invertebrates, including sponges and jellyfish, retain the same chromosomal structure as their primitive ancestors over 600 million years ago. This discovery underscores the conservatism of evolution and provides a key link between humans and our distant ancestors.

Genomic effects of inbreeding on Scandinavian wolves

Researchers at Uppsala University studied the genomic effects of inbreeding on Scandinavian wolves, finding that 10-25% of original genetic variation was lost after five generations. The study revealed a surprisingly large number of genetic variants disappeared, highlighting the risks of inbreeding in endangered species.

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Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Bronze Age women altered genetic landscape of Orkney, study finds

Ancient DNA study reveals Bronze Age women replaced local population in Orkney, contrary to historical assumptions about European expansion trends. Genetic analysis suggests a complex and varied process of negotiation between indigenous males and newcomers from the south over many generations.

Unravelling the ancient stories hidden in DNA

Scientists have discovered that the genomes of marine invertebrates have been surprisingly stable across deep time. The study found that chromosomes are remarkably similar among sponges, jellyfish, scallops, and even humans, with some genes traveling together for almost a billion years.

Are scientists being fooled by bacteria?

Researchers developed a method called 6mASCOPE that measures DNA tagging system accuracy and distinguishes bacterial from human DNA. The study found high levels of methylation in plant, fly, mouse, and human cells, but mostly attributed to contamination.

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