Articles tagged with Evolutionary Genetics
Researchers have developed a tool that maps breast cancer growth and highlights the role of surrounding cells in controlling disease spread. The new technology provides insights into cancer evolution, genetics, and environmental interactions.
Researchers identified a genetic variant that predisposes people to being slim, carried by 60% of Europeans. The variant affects the amount of fat stored in the body and is associated with the biochemical signalling pathway that tells cells what nutrients are available.
A genetic variant associated with a 10-15% reduction in fat storage has been identified in 60% of Europeans. Researchers studied the effect of this variant in mice and found it to be linked to leanness, highlighting the complex interplay between genetics and obesity.
Researchers have published seven draft genomes for Nordic hare species, including three heath hares with distinct grey/blue winter pelage. The findings suggest the heath hare colonized Scandinavia from the south after the last ice age, diverging from the mountain hare population.
A new study found that large river dams are significant barriers to platypus movements, leading to increased genetic differentiation and vulnerability to threats. This restriction of movement limits gene flow between groups, making separate populations more susceptible to inbreeding depression and loss of adaptive genetic variation.
Researchers used DNA from two ancient human individuals to unravel the deep demographic history of South America, providing new genetic evidence supporting existing archaeological data. They also discovered migrations along the Atlantic coast for the first time and found evidence of Neanderthal ancestry within ancient genomes.
Scientists discovered that ancient fish favored cold, dark waters of the deep sea, challenging the assumption that shallow habitats have always been diverse. The study revealed three major events that drove speciation rates in the deep sea, including the breakup of Pangea and the Cretaceous Hot Greenhouse period.
Researchers at CSHL have created genetic blueprints for two types of groundcherry, which can guide plant geneticists in unlocking their potential. The new models also uncovered a gene essential for inflated calyx development, shedding light on the evolutionary process behind this unique trait.
Researchers from Trinity College Dublin have identified several new species of sunbirds, including the Wakatobi Sunbird, found on tiny Indonesian islands. The study reveals unique evolutionary processes and adds to our understanding of the importance of biodiversity in this region.
Researchers have discovered a family of selfish genes, wtf, that have survived for over 100 million years in yeast, contradicting established beliefs on their longevity. These 'killer meiotic drivers' transmit themselves to half of offspring and destroy reproductive cells without being suppressed by natural selection.
Researchers analyzed DNA from victims and survivors of the Black Death to identify genetic differences that determined who lived and died. The study found four genes involved in immune defense against pathogens, with versions of these genes linked to increased susceptibility to autoimmune diseases.
Researchers analyzed DNA from 13 Neandertals, finding evidence of a close-knit community with 10-20 individuals. Genetic data suggests that female migration played a key role in maintaining the group's cohesion, contradicting previous theories about male-dominated movements.
Scientists are conducting a first-of-its-kind study to investigate the origin of psychedelic compounds in fungi, including psilocybin found in 'magic mushrooms'. The research aims to understand the evolution of these compounds and their potential applications in medicine and conservation.
Genetic and genomic technologies can protect marine life by identifying illegally harvested seafood products and monitoring disease outbreaks. Assisted evolution and synthetic biology could also benefit ocean ecosystems by introducing beneficial species or manufacturing products in the lab.
A new dataset provides an unprecedented insight into the Arctic Ocean's biological life, revealing a year's worth of microbial communities and their responses to climate change. The EcoOmics dataset aims to guide conservation efforts and provide evidence for novel biology that may influence our understanding of evolution on Earth.
Researchers found that horizontal gene transfer can accelerate bacterial adaptation under most growth conditions, but not all. By analyzing the fitness effects of gene transfer, they can predict when it will provide an advantage.
Researchers at the University of Zurich have successfully decoded the genome of Aldabrachelys gigantea, one of the world's two remaining giant tortoise species. The reference genome provides crucial information for breeding programs in zoos to represent genetic diversity and conservation efforts across East Africa and Madagascar.
Researchers from University of Konstanz discovered a new species of cichlid fishes in Nicaraguan crater lake Xiloá through genetic hybridization. The hybrids exhibit transgressive traits and occupy a unique ecological niche, outcompeting parental species for food resources.
Researchers identified 49 plant genes transferred to the silverleaf whitefly genome, including genes neutralizing toxins produced by plants as a defense mechanism. This discovery opens up new research opportunities for innovative pest control methods based on plant breeding, potentially reducing pesticide use.
Researchers uncover previously unknown lineage of wild goats over 10,000 years old in the Taurus Mountains of southern Turkey. The discovery sheds light on the region's faunal history and highlights the impact of climate change and human activity on ancient populations.
This study reveals genetic insights into artificial selection and ecological adaptation in silkworms, identifying 468 domestication-associated genes and 198 improvement-associated genes. The pangenome dataset also sheds light on the origins of domesticated silkworms and their economic traits.
A large wingless wood-eating cockroach unique to Australia's Lord Howe Island has been rediscovered at the foot of a single Banyan tree. The species was thought extinct since the 1930s, but its genetic difference from offshore relatives suggests it may have survived due to co-evolution with ground-dwelling insects.
Researchers found the moths originated from the Baja Peninsula and Arizona, with a new subspecies discovered in western North America. The study recommends using synthetic pheromones to control the invasive pest.
A study published in Science found that more than one-tenth of the world's terrestrial genetic diversity may already be lost due to climate change and habitat destruction. This could have serious implications for species' ability to adapt to climate change, highlighting the need for urgent conservation efforts.
A new computer program, ExtRaINSIGHT, has been developed to track harmful mutations in the human genome throughout evolution. The study found three regions of the genome that are extremely sensitive to mutations, including splice sites, miRNA molecules, and central nervous system genes.
Brown algae's unique pigments have evolved through a complex genetic pathway, enabling them to harness more light energy than green plants. This discovery could lead to insights into fucoxanthin's health applications and improved photosynthetic efficiency for biofuels production.
Researchers deciphered the diversity and evolution of nerve and gland cell types in sea anemones, revealing common progenitor populations and conserved regulatory mechanisms. The study highlights a remarkable ability of sea anemones to maintain neural balance throughout their lives.
A recent genetic study has found that three-quarters of the Early Medieval population in Eastern England was comprised of migrants originating from Continental regions bordering the North Sea. These migrants intermarried with local populations, but integration varied greatly from region to region.
Research found that human brain hemispheres have distinct functional patterns, with regions on the left and right sides specialized for different tasks. Individual differences in these arrangements were heritable, suggesting genetic influence, while environmental factors also play a role. The study also compared humans to monkeys, find...
A new study finds that lab adaptation involves mutations to highly conserved proteins, but natural adaptation exhibits more complex patterns, including non-conservation within functional domains. Lab conditions differ significantly from natural environments with variable and changing selective pressures.
Researchers produced human and chimpanzee brain organoids to investigate the role of ARHGAP11B in brain evolution. The study found that the gene is essential for neocortex development, with its absence or inhibition leading to decreased levels of critical brain stem cells.
A new study from Harvard University identifies the genes and genetic sequences that orchestrate the formation of the human pelvis during pregnancy. The research shows that key pelvic features form around 6- to 8-week mark, including a curved and basin-like shape.
Researchers at Stockholm University solved the mystery of the supergene responsible for distylous flowers with differing lengths of male and female sexual organs. The study reveals that the supergene itself varied in length, with a dominant form containing about 260,000 base pairs of DNA.
Researchers found that modern human brains produce more neurons than Neandertal brains, particularly in the frontal lobe, due to a single amino acid substitution in the TKTL1 protein. This increase is attributed to changes in metabolism and membrane lipid synthesis.
Threespine stickleback fish evolved resistance to freshwater tapeworms by forming scar tissue around them, which prevents the worms from growing. However, this defense has a significant fitness cost for female sticklebacks, as they are 80% less likely to successfully breed due to the accumulated scarring.
Research suggests that COVID-19 patients can transmit viruses with multiple genetic sequences simultaneously, which may impact the development of new variants. This complex sequence diversity highlights the need for continued research into the evolution and transmission of SARS-CoV-2.
A new study reveals that the emergence of a new gene called PGBD1 is linked to the evolution of a new structure in nerve cells. PGBD1 controls paraspeckles, tiny structures that act like traps for RNAs and proteins, and its regulation is crucial for nerve cell development.
Two papers published in Nature Plants unveil the first full-length genomes for homosporous ferns, a group containing 99% of modern fern diversity. The Ceratopteris genome suggests that ferns stole genes from bacteria for anti-herbivory toxins.
Researchers have identified eight new species of tiny brown geckos in Madagascar's rainforests, expanding our understanding of their distribution and evolution. The discovery highlights the importance of continued sampling across the region to uncover new species.
Researchers found that corals can pass somatic mutations to their offspring, which increases genetic diversity and provides a potential route for evolutionary adaptation. The discovery challenges conventional wisdom on the role of reproductive cells in evolution.
Researchers identified a group of Ashkenazi Jews who fell victim to antisemitic violence during the 12th century, shedding new light on Jewish medical history in Europe. The study suggests that a bottleneck event shaped the modern-day Ashkenazi Jewish population prior to the 12th century, earlier than previously believed.
Researchers identified 15 instances of mucinization, where new mucins emerged from non-mucin proteins by adding repeating sequences. This process transformed the proteins into mucins with gooey consistency, contributing to their various biological functions.
Researchers successfully produced mice with novel and sustainable karyotypes, mimicking evolutionary changes on a million-year scale. Chromosome-level engineering enables insight into how rearrangements influence evolution and potentially correct misaligned chromosomes.
A new study sheds light on the ancestry of manatees, tracing their evolution back 47 million years to northern Africa. The research suggests that modern manatees migrated from South America to the Caribbean and North America around 34 million years ago, with some species thriving in communities for millions of years.
A new study at the University of Helsinki reveals how the actin cytoskeleton in cells is controlled in an evolutionarily distant Leishmania parasite. The findings provide tools to combat leishmaniasis and trypanosomiasis by exploiting structural differences between parasite and human actins.
Scientists reconstruct evolution of complex multicellular organisms using genomic data and computational models, revealing gradual changes that began early in evolution. The research reveals distinct paths taken by animal and fungal lineages, shedding light on their shared eukaryotic supergroup.
Researchers found that genetic makeup of mice affects bacteria in their gut, with heritable species and co-evolution observed. The study's findings could provide new insights into treating human gut-related conditions like Inflammatory Bowel Disease (IBD).
The University of Guam is conducting a four-person research team's study on the genetics of corals from the Northern Mariana Islands to understand coral population connections, diversity, and adaptations. The study aims to identify potential reserves for declining reefs and assess the impact of warming waters.
A new DNA extraction technique has enabled researchers to analyze genetically diverse mollusc species from museum collections, shedding light on their evolutionary history and informing conservation management. The method's success opens up novel research avenues, particularly for endangered or never-before-seen-alive molluscs.
Bacteria in the Neisseriaceae family evolved to divide along their longitudinal axis without separating, forming caterpillar-like filaments that aid in attachment and cooperation. This unique strategy helps them survive in the oral cavity, where competition is high.
The winning image depicts a parasitic fungus infecting a fly, while other images showcase the relationships between species, biodiversity under threat, and research in action. The competition highlights the intersection of art and science, celebrating ecologists' creativity to protect the natural world.
A new paper in The Quarterly Review of Biology reviews studies on workload distribution and division of labor to better understand individual differences in cooperation. The authors argue that integrating collective action and offspring care literatures could lead to a deeper understanding of these factors.
A team of researchers developed a deep learning pipeline to analyze vascular system images of plants with high accuracy. The pipeline can detect vascular bundles, identify specific zones, and perform statistical analysis of traits in different stem internodes. This study has the potential to improve crop resilience and food security.
Researchers at the University of California San Diego have developed a precision-guided sterile insect technique (pgSIT) to control invasive fruit fly populations. The technology uses CRISPR editing to target key genes in female viability and male fertility, resulting in a fertility dead end for the species.
A new study reveals that four living amphibian clades, including the dominant Plethodontidae family of lungless salamanders, develop lungs as embryos but lose them as adults. This finding sheds light on the evolution of lung loss over millions of years and suggests that losing lungs may have enabled their remarkable evolutionary success.
A Texas A&M AgriLife Research project investigates the ages-long interaction between parasitic lice and mammal species, including humans. The researchers aim to answer why various louse species parasitize specific hosts and what makes these species good hosts.
A new study found that 'gaps' within DNA protein and sequence alignments can provide valuable information about nucleotide and amino acid substitutions. The finding is particularly relevant for studying distantly related species.
A newly identified species of Liberibacter, a family of bacteria known for causing citrus greening disease, is rapidly evolving its ability to infect insect hosts. The research team found 21 genes associated with infectious qualities and identified mutations affecting pilus proteins that allow the bacteria to move into host insects.
Scientists have gained insight into how evolution takes place and how several species evolved from a single one by studying trees found in the Galapagos Islands. The research revealed genetic variations associated with vascular development, growth, adaptation to salinity, and flowering time.
A self-pollinating monkeyflower plant lost 13-24% of its genetic variation within nine generations when isolated from bumble bees. This rapid loss of genetic variation could have devastating impacts on the plant's ability to adapt to changing environments, highlighting the importance of pollinators for plant survival.