Research on how genes and species change over time. Covers ancient DNA, longevity in bats, plant lineages, and insect evolution.
Researchers propose a new atavistic model of cancer, suggesting that ancient genes and reversions to ancestral forms are responsible for cancer's ability to survive and proliferate. The Serial Atavism Model challenges the conventional standard model of cancer, offering a novel perspective on the disease.
Researchers analyzed 12,000-year-old fish bones from three-spine sticklebacks to study the evolutionary process. They found that genetic variants enabling adaptation to freshwater existed in ocean populations thousands of years ago.
Researchers discovered innate immune markers increased in frequency in modern people from a region that experienced the plague, suggesting these markers might have evolved to resist the disease. The study also found changes in allele distribution for immune-related genes, which could be evidence of past Yersinia pestis exposure.
Researchers from McGill University studied threespine stickleback fish adapting to seasonal changes, finding genetic shifts that mirror past adaptations. The study's findings suggest predicting evolutionary future of populations under environmental stressors like climate change.
The study of Xerocrassa montserratensis reveals new insights into the conservation of this endemic and threatened species. The researchers identified genetic groups in different areas where sub-species had been described, providing a better understanding of the species' population structure.
A recent study led by NSU researcher sequenced the leopard genome, showing distinct genetic patterns between African and Asian populations. The analysis suggests that all African leopards should be considered a single subspecies due to abundant gene flow across Africa.
Researchers discovered that a growth factor, BMP11, drives the development of male water strider's long legs and fighting behavior. Knocking out this gene in males reduced leg size and aggression, highlighting its role in hyperallometry.
A recent study published in Molecular Biology and Evolution reveals that the DNA replication machinery of Mimivirus, a giant virus, is ancient and evolved over time. The research suggests that Mimiviral genes related to DNA replication are subject to purifying selection, indicating their essential role in the organism's survival.
A recent study led by Shinshu University found that flower size is correlated with pollinator size in different mountain regions, evolving independently in each area. Despite genetic similarity between plants across regions, flower sizes varied greatly, suggesting parallel evolution of this trait among mountains.
Three manatee species share a common ancestor after the Amazon Basin was formed, with genetic data showing adaptation to environments influenced their evolution. The research adds new information on the evolutionary history of aquatic mammals, shedding light on how geological events shaped their distribution.
A recent study uses phylogenetic methods to integrate vertical and horizontal gene transmission, revealing that genes travel vertically two-thirds of the time. This analysis predicts a root between two major clades, Terrabacteria and Gracilicutes, shedding light on early bacterial evolution.
Researchers found that different species use distinct genetic mechanisms to adapt to desert environments, offering a silver lining for species facing climate change. The study's findings have implications for developing gene therapies to treat human dehydration-related illnesses like kidney disease.
Researchers at the University of Kansas have described a new species of fanged frog found in the Philippines, which was previously thought to be the same as another species on a neighboring island. The Mindoro Fanged Frog has distinct genetic differences and unique mating calls, setting it apart from its cousin.
A study by Rice University biologist Kory Evans found that flatfish evolved rapid skull asymmetry due to trait co-evolution. This process led to the development of unique traits across the skull, resulting in increased integration and adaptability for these fish.
Researchers found that Eastern and Western house mice developed identical genetic changes to cope with cold temperatures, building bigger nests and growing heftier. This study demonstrates the predictability of evolution in mammals, with implications for understanding human evolution.
Researchers found that corals' ability to grow calcium carbonate skeletons evolved between 308 and 265 million years ago, with necessary proteins present in their soft-bodied ancestors. The team identified genes responsible for transporting calcium and removing protons, as well as an acid-rich protein involved in skeleton building.
A new study resolves the horned crocodile's evolutionary relationships, placing it on a separate branch of the crocodile family tree. The research suggests that modern crocodiles likely originated in Africa, contradicting previous scientific thinking.
The study unravels the evolutionary and genetic origins of flatfish specialized body plan through comparative genomic analysis. Key findings include significant alteration in genes related to visual perception, immune response, and musculature development.
Grasses can incorporate DNA from other species into their genomes through lateral gene transfer, giving them an evolutionary advantage. This process may allow crops to adapt to new environments quicker and be more resistant to climate change.
Salk researchers have traced the development of spinal cord neurons using genetic signatures, revealing new ways of classifying and tagging subsets of cells. The findings offer a precise way to study the function of spinal cord neurons and their role in regulating body movements.
A study found that wind patterns strongly affect genetic differentiation, gene flow, and genetic diversity in tree populations. Downwind populations tend to exhibit high genetic diversity.
Researchers analyzed genome sequencing data from 320 individuals to understand how human populations adapted to Pacific island environments. They found that ancient admixture with Denisovans and Neanderthals influenced the current state of health in South Pacific populations.
Researchers from Kobe University and Chiba University developed a flexible method to create genetic switches for yeast, allowing for the control of gene expression. They successfully produced yeast that biosynthesized orange pigment under AND-gated control, paving the way for sophisticated, artificially regulated cells.
Researchers discovered that humans evolved higher eccrine gland density due to accumulated changes in the hECE18 enhancer region, which drives EN1 expression. This trait is thought to have adapted to early hominins' hot habitats, promoting survival and evolution.
Adriana Darielle Mejía Briscoe, a University of California, Irvine professor of ecology & evolutionary biology, has been awarded a 2021 Guggenheim Fellowship. She will conduct field research on the impacts of climate change on butterflies' visual and thermal adaptations.
A group of microbes that feed on chemical reactions triggered by radioactivity have been found to be at an evolutionary standstill for millions of years. Their identical genetic makeup suggests they have not changed since their physical locations separated during the breakup of supercontinent Pangaea.
Researchers found that tumour samples from over 2,600 patients with different types of cancer contain a high prevalence of genetic diversity within individual tumours. This variation is a challenge for doctors as treatment may not be effective against another subclone, and certain subclones can initiate tumour spread or drug resistance.
Researchers found that spatial constraints from the surrounding environment significantly affect tumor evolution, leading to diverse mutational patterns among patients. The study highlights the importance of tissue architecture in regulating tumor growth and behavior.
The Pyrenean Ibex's decline was driven by a combination of hunting and infectious diseases, which further reduced its already low genetic diversity. The species' eventual extinction highlights the importance of historical biological collections for genetic analyses of extinct species.
A team of scientists from UNIGE has identified a crucial role for a micro-peptide in determining the sperm that will fertilize an egg in Drosophila females. The peptide plays a key part in the competition between spermatozoa from different males, and its absence leads to reduced fertility in subsequent matings.
A Rutgers University-led study finds that overfishing is unlikely to be the primary cause of genetic changes in Atlantic cod. Instead, researchers suggest that addressing environmental factors such as climate change and reducing fishing pressure may be more effective in allowing cod populations to recover.
A large-scale study has identified a new genetic link to male infertility, revealing that unstable Y chromosomes are associated with a significantly increased risk of fertility issues. The study analyzed over 2,300 Estonian men and found that the genetic variation was more common in European descent populations.
Researchers found genetically distinct Fal Estuary maerl beds, shaped by geographical isolation and limited connectivity. Threats from shipping and climate change require targeted conservation efforts to protect these ancient ecosystems.
A University of Colorado Boulder-led research team found the Iberá Seedeater, an endangered songbird, used genetic shuffling instead of new mutations for speciation. The bird's unique behavior keeps it apart from closely related species.
Researchers identified a long-overlooked pattern in stomatal development, which suggests that living conditions regulate stomatal formation. The discovery uses the plant genus Callitriche, including both aquatic and terrestrial species, to reveal a coordinated delay in stomatal formation for aquatic species.
A team of biologists found that human pelvis sex differences are similar to those in chimpanzees, suggesting an ancient origin. The magnitude of these differences is only half as large in chimpanzees, indicating that modern humans inherited this pattern from earlier mammals.
A new study finds that female choice regarding mate traits drives the emergence of new species in Iberá Seedeater songbirds. The study reveals pre-mating isolation as a powerful force in maintaining reproductive barriers between co-occurring species, leading to rapid speciation.
Research on E. coli bacteria reveals that higher translation error rates lead to increased phenotypic variability at the single-cell level, affecting cell length and division time. However, population-level growth parameters show inconsistent correlations with mistranslation levels, highlighting the need for further investigation.
Scientists have isolated a genetic clue in the form of an RNA polymerase enzyme that offers new insights into the origins of life. The discovery provides evidence for the RNA World Hypothesis, suggesting that self-replicating RNA molecules were capable of driving chemical reactions essential for life.
Researchers from the University of Copenhagen have studied the giraffe's genome, discovering a key gene FGFRL1 that enables its extraordinary features, such as high blood pressure and dense bones. The study also found that giraffes spend less time sleeping than other mammals due to their unique circadian rhythm regulation.
Researchers at Stanford University developed a new technique to compare genetic differences between humans and chimpanzees, revealing significant disparities in the expression of genes SSTR2 and EVC2. This study provides insight into human evolution and potential causes of neuropsychiatric diseases.
The study confirms that the placenta is a 'dumping ground' for genetic defects, harboring mutations similar to childhood cancers. It tolerates major genetic flaws, unlike other human organs.
Researchers are using Drosophila melanogaster fruit flies to explore genetic underpinnings of susceptibility to environmental toxicants and develop precision toxicology. The study aims to identify molecular key event biomarkers in non-mammalian models that predict adverse health outcomes.
A recent study found that chimpanzees have been reconnected for extended periods during the most recent maximal expansion of African forests, contrary to previous assumptions. The team's comprehensive sampling and use of rapidly-evolving genetic markers revealed genetic connectivity mirrors geographic distance and local factors.
A study found that transposons play a key role in creating new genes through exon shuffling, a process that can lead to the creation of novel transcription factors. The research identified over 100 distinct genes fused with transposases across various species, including humans.
A team of researchers used a machine-learning approach to map the genetic and environmental connectivity of Aedes aegypti mosquitoes, a primary vector for diseases such as dengue fever and Zika. The study provides insights into the mosquito's adaptability to new landscapes and expanding range.
Paramecium uses a complex system to determine mating types, allowing for genetic variation and reproduction. The mechanism involves programmed genome rearrangements and small RNAs that eliminate unnecessary DNA sequences.
Research sequenced 65 tiger genomes revealing strong genetic differences between subspecies, which emerged recently due to climatic shift and human dominance. Conservation genomics can inform management strategies, highlighting the need for genetic rescue through hybridization or selection of adapted traits.
Researchers sequenced DNA from mammoth remains up to 1.2 million years old, revealing a previously unknown genetic lineage and showing that Columbian mammoths were hybrids of woolly and Adycha mammoths. The study provides new insights into how fast mammoths adapted to cold climates.
A recent study led by McGill University found that the Pacific and Caribbean crocodile populations have been separated for approximately 100,000 years, contradicting previous expectations of 3 million years. This discovery was made possible by reconstructing Ice Age sea levels and analyzing genetic variations in the crocodiles' genomes.
Researchers found a group of genes on chromosome 12 that reduces the risk of developing severe COVID-19 by around 20%, inherited from Neanderthals. These genes code for enzymes that help destroy viral genomes, and the Neanderthal variant is more efficient, providing protection against severe COVID-19.
A new study has sequenced the capuchin monkey genome, uncovering genetic clues about their long lifespan and large brains. The researchers identified genes associated with DNA damage response, metabolism, and insulin signalling, which may contribute to their longevity.
A new study found that male fruit flies with the most impressive sexual ornamentation also have super sperm that can outcompete rivals in the post-mating fertilization game. The researchers discovered a strong link between the males' competitive success at passing on their genes even after a female fly has mated with other flies.
Researchers at Oregon State University used thousands of genetic markers to determine the Pacific albacore's population structure. The study found that fish from different hemispheres intermingle and sometimes breed with each other, revealing a lack of clear boundaries between North and South Pacific populations.
Experts review current understanding of modern human ancestry tracing back to the distant past, identifying three key phases in human evolution. The study suggests that no specific point in time can be identified when modern human ancestry was confined to a limited birthplace.
A new study reveals that European Starlings in North America underwent rapid local adaptation, adjusting to temperature and rainfall variations through subtle genetic changes. The species' massive population size enabled the spread of beneficial gene variants across generations.
A group of caterpillars that eat cycad plants have evolved a toxic defense mechanism, resulting in bold colors and behaviors to deter predators. The study reveals the genetic consequences of this adaptation, including rapid evolutionary change and the development of proteins that destroy cells and remove dead cell debris.
A UCL-led team discovered 32 gene regions affecting facial features such as nose and lip shapes. The analysis of over 6,000 volunteers found that one gene, TBX15, was inherited from the Denisovans, an extinct group of ancient humans.
A recent genome mapping study by the University of Copenhagen found that our common fish ancestor, which lived 50 million years ago, already carried genetic codes for limb-like forms and air breathing. This discovery challenges the long-held belief that limbs and lungs evolved separately during the vertebrate transition from water to l...
Harvard scientists engineered zebrafish with limb-like appendages through a single genetic mutation, revealing the beginning formation of limb structures and their potential to evolve from fins. The discovery sheds light on vertebrate evolution, fin-to-limb transition, and the complex structures that enable land movement.