Articles tagged with Evolutionary Genetics
Josef Uyeda aims to bridge the gap between short-term evolution studies and long-term outcomes using computational tools and resources. He will analyze existing datasets to understand how species adapt to climate change and extinction.
A team of researchers has identified a key gene, POPOVICH, responsible for the development of nectar spurs in Aquilegia. The study used a spurless species to pinpoint the gene and found that it promotes cell divisions in the regions where the spur develops.
Researchers at UC Santa Barbara have identified a gene critical to the development of columbines' iconic spurs, which has led to rapid expansion in the genus. The discovery provides new insights into how key innovations evolve and could shed light on the genetic changes underlying this trait.
A new study reveals that bats can host the Ebola virus without contracting the deadly disease, thanks to their unique cell structure. The research found that bat cells induce changes in the virus that make it less capable of harm, allowing it to coexist with its natural reservoir.
New research sheds light on penguin evolution, revealing a pivotal role for climate change in their geographic expansion. Genetic analysis indicates that penguins originated along temperate coastlines before expanding into Antarctic regions.
A Montana State University researcher contributed to a novel project that sequenced the genome of the tuatara, a reptile referred to as a 'living fossil.' The study reveals ancient features of amniote evolution and provides insights into human genetic lineage.
Researchers used ancestral sequencing to study the translational machinery in bacteria, finding that evolution prioritizes fixing problems over completing them. The team discovered that natural selection favors mutations with the largest fitness advantage, leading to a myopic approach that neglects other cellular modules.
Researchers at UC San Diego used CRISPR and evolutionary engineering to test foreign DNA in E. coli and observed that most mutations occurred in regulatory regions, not within the foreign gene itself. The study reveals the importance of systems biology in understanding biological function and its implications for genetic engineering.
Physicist John Barton at UC Riverside has received a $1.86 million NIH grant to develop methods for understanding how pathogens like HIV evolve and escape the immune system. His research could lead to the design of new and better treatments to fight disease.
The Undinarchaeota, a previously unknown phylum of aquatic Archaea, have been found to likely depend on partner organisms for growth, while also conserving energy through fermentation. Their discovery provides new insights into the diversity and evolutionary history of Archaea.
Researchers propose a new hypothesis that the Y chromosome is protected from extinction by carrying 'executioner genes' that self-regulate and ensure successful sperm production. These genes, which regulate meiotic silencing, are toxic when activated at the wrong time, protecting the Y chromosome from loss.
A new study reveals that marine angelfish exhibit the highest incidence of hybridization among coral reef fish, with nearly half of all known species creating hybrids. The research found that angelfish can hybridize even between distantly related species and across vast genetic distances.
A genome-wide comparison of eastern and western monarch butterflies found they share identical genetic diversity, contradicting long-held assumptions about their distinctiveness. The study suggests environmental factors shape behavioral differences in the butterflies' migratory patterns.
Scientists discovered extinct strains of smallpox in Viking skeletons, proving the killer disease plagued humanity for at least 1400 years. The ancient strains were genetically different from modern smallpox, and their presence pushes back the confirmed existence of smallpox by a thousand years.
A new study from Columbia University provides a blueprint for using genomics to help combat climate change by identifying corals that can adapt to warmer seas. Researchers analyzed genetic data from 237 samples collected at 12 locations along the Great Barrier Reef, finding multiple genetic variants associated with bleaching tolerance.
Researchers identify genetic mutation contributing to reproductive isolation between carrion and hooded crows due to differences in plumage color. The mutation appears to have been favored by natural selection, potentially providing a selective advantage in hot regions.
A genetic study spanning seven countries has identified distinct population clusters of the American Crocodile, with regional differences found in Northern, Central, and Southern America. The findings highlight the importance of habitat conservation and management strategies tailored to each population's unique needs.
Researchers identified 37 supergenes in wild sunflower populations that govern the modular transfer of traits important for adaptation. These supergenes can be truly massive, with the largest comprising over 100 million base pairs and 1,819 genes.
A study found that fast rates of morphological evolution do not need to coincide with taxonomic diversification in reptiles. The team discovered that accelerated rates of evolution correspond to the origin of unique body plans, but varying rates can result in similar functional adaptations.
Histones may have evolved to adapt to oxygenated environments by reducing toxic copper, a crucial element for biological processes. The study reveals a new function of the histone H3-H4 tetramer as an oxidoreductase enzyme, making harmful copper oxidation state safe for use inside cells.
Genetic study reveals modern sled dog breeds share a distinct lineage that emerged at least 9,500 years ago. The analysis of ancient and modern Arctic dog genomes suggests gene flow from Siberian Pleistocene wolves, highlighting the importance of sled technology in human subsistence.
Researchers found an entry point for suppressing spontaneous antibiotic resistance development in E. coli by targeting membrane transport and chaperones. The study provides new molecular targets to improve antibiotics' effectiveness.
Researchers found that genetic influences account for 45% of the variation in women's affectionate behavior, whereas environmental factors explain 55%. Men's affectionate behavior is entirely determined by their surroundings. The study aimed to determine whether social behaviors are learned or genetically driven.
Researchers from the University of Helsinki found that genetic parallelism, a phenomenon where similar changes occur in different populations, is approximately 10-fold higher in the Eastern Pacific compared to the rest of the world. This suggests that the conditions for parallel evolution may be exceptional rather than common.
Researchers find that the human-specific gene ARHGAP11B causes an enlarged neocortex in common marmosets, a non-human primate. The study suggests that this gene may have played a key role in the expansion of the human neocortex during evolution.
Researchers at UC Davis propose a novel model of sex evolution before and during grapevine domestication, revealing the genetic basis of hermaphroditism. The study finds that female individuals arise from a recessive deletion in a gene necessary for pollen germination.
A new study sequenced the genome of Gardenia jasminoides and discovered how it produces crocin, a compound with medicinal properties. The research highlights an evolutionary process called tandem gene duplication that enables plants to expand their genetic toolkit and create new capabilities.
A team of Kyoto University researchers has discovered an intimate connection between methylation and the body's circadian rhythms, linking ancient mechanisms in bacteria to humans. Disruption of methylation can cause various pathologies, including cancer, and inhibiting it in mice and human cells disrupted their body clocks.
Scientists used genomic analysis to assess genetic variability in 17 seal species, finding that past population fluctuations have had a significant effect on contemporary populations. The study estimates the risk of genetic impoverishment and inbreeding, with implications for conservation efforts.
A new gene has been discovered that reduces pollen number in plants, a trait previously thought to be detrimental. The RDP1 gene promotes protein production, suggesting a potential advantage in self-fertilizing species.
A team of researchers found that sweat bees switch from solitary to social behavior by repurposing ancient genes, challenging the long-held assumption that new genetic variants are always necessary for evolution. The study provides evidence that environmental influences can drive the evolution of complex traits like social behavior.
Scientists found that building blocks of DNA and RNA can spontaneously form and co-exist in early Earth conditions, challenging the 'RNA world' theory. The research discovered four building blocks for DNA and RNA that can arise from the same reagents and conditions.
A study published in the Journal of Mammalogy found that Wyoming pronghorn exhibit high levels of genetic connectivity across the state, contradicting previous research suggesting barriers to gene flow. The researchers suggest periodic monitoring of genetic structure and diversity as part of management strategies.
A new study proposes that SARS-CoV-2's emergence was facilitated by genetic recombination among bat and pangolin coronaviruses. The virus' receptor binding motif was introduced through recombination with pangolin coronaviruses.
Researchers used statistical physics models to study biological complexity and found that organisms are restricted to a low level of dimensionality. This means that their essential building blocks appear to be linked to each other, with variations fitting a one-dimensional curve or low-dimensional surface regardless of the environment.
The study reveals strong genetic resemblance among Bronze Age Southern Levant populations, including a significant Caucasus/Zagros component and Chalcolithic Zagros ancestry. The movement of people from the northeast into the region started as early as 4,500 years ago and continued throughout the Bronze Age.
The vertebrate ear's unique structure and development have puzzled scientists. A new study proposes that this complexity increased the
A genome-wide analysis has identified 19 new genetic risk factors for problematic alcohol use and confirmed 10 previously known factors. The study also found shared genetic associations with psychiatric disorders such as depression and anxiety.
A new study maps genetic diversity in terrestrial mammals, revealing regions with high evolutionary history and stable climates as strongholds of genetic diversity. The research suggests that conservation efforts should prioritize the protection of these 'arks of biodiversity' due to climate change.
A study published in BMC Biology suggests that northern and southern Italian populations diverged genetically as early as 19,000-12,000 years ago. The research found distinct genetic variants between individuals from different regions, with adaptations to climate-specific genes.
Researchers analyzed ancient Italian DNA, revealing a complex mosaic of ancestry components and genetic peculiarities shaped by environmental interactions. These adaptations contribute to reducing disease risk, favoring longer lifespan in some cases.
Scientists have identified two genes responsible for a melanoma that develops near the tails of male highland-sheepshead hybrids. These findings provide insight into the genetic causes of hybrid dysfunction and its effects on disease, highlighting the importance of understanding gene interactions in different species.
A team of researchers identified a previously unknown genetic variant in the FBN1 gene that is strongly associated with lower height in Peruvians and Native Americans. The variant, E1297G, was found exclusively in individuals of Native American ancestry and showed an average effect of 2.2 centimeters reduction in height.
Researchers have discovered a gene responsible for virgin births in Cape honey bees, allowing workers to lay female eggs without sex. This discovery has significant implications for understanding evolutionary transitions and potentially controlling asexual reproduction.
A new study suggests that butterfly and moth eyespots likely evolved independently, with distinct developmental pathways.
The human genome's complexity hinders personalized medicine by having an immense ability to change and cope with issues, context matters in our genome. Researchers conclude that precision medicine is crucial but must consider the full genomic blueprint including 'unnecessary' elements.
Researchers found that regulatory mutations in TBX5 and PITX1 genes cause foot feathering in both domesticated breeds of chickens and pigeons. This study demonstrates a remarkable convergence in the evolution of this trait across species, suggesting that favored mutations have been spread through strong phenotypic selection.
Researchers found that genetic variants at Tbx5 and Pitx1 contribute to foot feathering in both chickens and pigeons. A 17,000 base-pair long deletion near Pitx1 removes the same exact region in both species, indicating similar mutations and molecular pathways.
A comprehensive comparative study suggests that early mutation rates were much higher and gene jumping occurred earlier than thought, making a simple interpretation of the 'family tree' of life misleading. However, it does show that early evolution was wildly different from present-day organisms.
A new children's book introduces genetics to youngsters of primary school age through a rhyming narrative, explaining DNA and the role of nature and nurture in making each person unique. The book aims to engage young children with science, building on research that shows teaching genetics before evolution improves pupil understanding.
A new study analyzes thousands of phylogenetic trees to shed light on the nature of the earliest living organisms. It suggests that early mutation rates were much higher than at present, leading to a complex 'family tree' of life. The research provides insight into how quickly early organisms may have evolved billions of years ago.
Scientists used chromosomes to study early events in vertebrate evolution, including the hybridization between two species of primitive fish. They found evidence of genome duplication and identified 17 ancient chromosomal units that were shared among jawed vertebrates.
Researchers discovered evidence of milk processing in ancient pottery from east Africa, confirming the story that bones have been telling us about pastoralist societies' way of life. The findings suggest that herders who specialized in cattle were drinking milk and survived better due to lactase persistence.
A new formula built with mathematical modeling can accurately reconstruct the diversification history of taxa, even when fossils are rare or extinct, say Oregon and British Columbia researchers.
Researchers have created an algorithm that can visualize the evolution of genetic mutations, revealing patterns in how proteins change over time. The tool, called minimum epistasis interpolation, helps scientists understand how specific mutations combine to affect protein function.
A team of scientists discovered that genetic alterations in the immune system of pipefishes and seahorses allow them to tolerate paternal genetic information and develop their offspring. The study found that genes involved in female mammalian pregnancy are also activated in male pregnancy, suggesting similar molecular mechanisms.
Researchers found a gene influencing structural color in butterflies, which produces intricate nanostructures with optical properties. The study also reveals that most butterfly patterns have a mix of pigment color and structural color, with the latter having a stronger impact on wing color.
Researchers found that regulatory switches involved in knee development also play a role in osteoarthritis, a partially heritable disease affecting 250 million people worldwide. The study suggests that subtle modifications in the knee's shape may increase risk of developing osteoarthritis over time.
Researchers have made significant progress in gene editing tools for ocean microbes, enabling functional studies of thousands of new genes. This breakthrough has the potential to improve our understanding of life's origins, biotechnology, medicine, and pharmacology.
Researchers explore using CRISPR in nongenetic model plants, overcoming technical obstacles with adapted transformation systems. Polyploidy studies reveal the biological underpinnings of genetic consequences.