Researchers found that fingolimod inhibits HIV replication by targeting S1P receptors, reducing viral binding and fusion. The compound also activates antiviral restriction factor SAMHD1, leading to a decrease in total and integrated HIV levels.
A new study finds that the Mount Polley tailings spill in 2014 is still affecting Quesnel Lake, with turbidity increasing each spring and fall due to resuspended contaminants. The phenomenon raises concerns about long-term impacts on the lake's ecology, including effects on fish populations and algal communities.
A New Zealand-led international study used satellite images and citizen science to uncover the secret lives of crabeater seals in Antarctica. The researchers found that crabeater seal distribution overlapped mostly with Antarctic krill habitat, highlighting the importance of conserving this ecosystem.
A new study found that playing on soccer teams with Muslim players increased tolerance among Christians towards their Muslim teammates in the league, but not beyond. This approach showed promise for rebuilding social ties and promoting coexistence after war.
Researchers found that flu vaccines induce short-lived bone marrow plasma cells, which decline to pre-vaccination levels within a year. The study suggests that the longevity of flu vaccines can be improved by enhancing the persistence of these cells.
Recalling memories from an observer-like perspective activates different brain regions than recalling through one's own eyes. This new research suggests that adopting this viewpoint may aid in therapeutic treatments by reducing the intensity of emotions associated with troubling memories.
Researchers at the University of Missouri are developing online resources to support early-career teachers in implementing effective classroom management practices, which have been shown to lead to improved student behavior and academic outcomes.
Researchers compared COVID-19 excess deaths in New York to those during the 1918 influenza pandemic, finding a similar increase in mortality rates. The study aimed to provide historical context for understanding the current pandemic's impact.
Research reveals that forest restoration can replenish carbon storage and preserve biodiversity, with actively restored forests recovering 50% faster than naturally regenerating ones. The study found that degraded forests can recover up to 2.9 tons of aboveground carbon per hectare annually if protected from agricultural conversion.
Researchers at Princeton University developed OptoBinders, light-switchable molecular tools that control cellular processes. These antibody-like proteins can bind or release targets in response to blue light, offering new capabilities for protein purification, biofuel production, and targeted cancer therapies.
A new study found that adults with sickle cell disease who received medical marijuana required fewer hospital visits than those who did not. Receiving medical marijuana was also associated with an increase in the use of edible cannabis products, which may help individuals better tolerate their pain at home.
Groundbreaking research from the University of South Australia confirms that smiling can alter perception of facial expressions and body language, generating more positive emotions. The study found that facial muscular activity stimulates the amygdala, releasing neurotransmitters to encourage an emotionally positive state.
Researchers studied COVID-19 outcomes in French nursing homes that implemented voluntary staff confinement, finding improved mortality rates among residents. The study suggests that staff confinement can help reduce the spread of COVID-19 in long-term care settings.
A new study found a significant increase in domestic violence injuries during the COVID-19 pandemic, with more severe injuries reported despite fewer patients seeking help. The study suggests that fear of contracting infection and limited access to ambulatory sites may be preventing victims from reporting abuse.
A recent study found that Muslim teammates improved Christian players' behavior towards their peers in an Iraqi soccer league, but this effect did not generalize to other social contexts. The research highlights the value of intergroup interventions for achieving post-war peace, but also reveals limitations in building lasting social c...
A study found that independent search engines often return anti-vaccine websites, while internet giants like Google.com typically do not. This raises concerns about the spread of misinformation and its impact on vaccine hesitancy.
Researchers found that patients with diabetes and gout are at a higher risk of undergoing amputations compared to those without the conditions. The combined condition was associated with an amputation rate of 0.77 percent, significantly higher than the 0.03 percent in those without either disease.
Researchers discovered that simultaneously targeting two energy-production pathways within cancer cells can help overcome the effects of a cancer-causing mutation in DIPG. In mouse models, inhibiting both pathways at once significantly improved survival rates compared to targeting each pathway individually.
Researchers developed AI-powered software to assess geographic atrophy, a common cause of blindness in industrialized nations. The study found that integrity of light-sensitive cells outside main lesions predicts disease progression.
A recent study published in The Economic Journal found that child disability can have a significant impact on the educational outcomes of their older siblings. The researchers analyzed data from Florida and Denmark and found that the second-born child was more adversely affected cognitively than the first-born child when the third-born...
Research found that dialysis facilities with larger proportions of Black and Hispanic patients had significantly lower flu vaccination percentages than less diverse facilities. The study highlights the need for targeted vaccination outreach programs to protect vulnerable communities.
A 429-million-year-old trilobite fossil's internal structure reveals similarities with modern bee eyes and compound eyes of crustaceans. The findings suggest that vision principles in these insects have remained largely unchanged since the Palaeozoic era.
A review paper examines the influence of systemic inequalities on ecology and evolution, finding that racism reduces biodiversity, increases urban heat island effects, and augments climate crises. The authors advocate for environmental justice and anti-racism practices to transform biological research and conservation.
Researchers at Mississippi State University recommend using an integrated approach that combines seed-applied nematicides with in-furrow nematicides to manage reniform nematodes in cotton. This approach can improve cotton yields while reducing production costs, making it a economically viable option for farmers.
Researchers successfully engineered bacteria to produce a synthetic building block, a 21st amino acid, which prompts the bacteria to produce a protein that fluoresces under metabolic stress. This breakthrough enables the design of novel proteins and organisms with useful functions.
Buckled graphene mimics colossal magnetic fields, altering electronic properties for novel quantum materials and superconductors. Researchers discover dramatic changes in material's behavior at extremely low temperatures.
Researchers found that powered flight potential evolved at least three times in theropods: once in birds and twice in dromaeosaurids. This challenges the traditional view of bird origins, presenting a more complex picture of experimentation with wing-assisted locomotion.
A recent study published in the Journal of Infectious Diseases found that stay-at-home orders significantly slowed the spread of COVID-19 in the United States. The study analyzed data from 45 states with stay-at-home orders and found an average doubling time increase of 12.27 days, indicating significant slowing of disease spread.
The KERI research team has successfully demonstrated the production of pixels with a 3D structure, overcoming the light intensity problem and achieving a 2-fold increase in brightness. This technology enables super-high-resolution displays with a pixel density of 5,600PPI, exceeding that of 8K QLED TV.
A new study found that yoga significantly improved symptoms for those with generalized anxiety disorder, but not as effective as cognitive behavioral therapy. Yoga was more effective than stress management, with 54% of participants experiencing improved symptoms compared to 33% in the control group.
A team of scientists, led by RMIT University, has developed a new class of quantum sensors using high-performance diamond particles embedded in conventional glass fibers. This breakthrough enables the creation of cheap quantum sensor networks for applications such as underwater monitoring and mining.
A new international study has shown that a newly developed treatment regimen for multidrug-resistant tuberculosis (MDR-TB) is highly effective, with an 85% success rate among patients with serious comorbidities. The regimens, bedaquiline and delamanid, offer a promising alternative to the historical standard of care, which has approxim...
Researchers at the University of Manchester have discovered a nanomaterial that mimics the 'magic angle' effect in twisted bilayer graphene, offering an alternative medium to study superconductivity. The new findings show strong electron-electron interactions in rhombohedral graphite, which could lead to game-changing effects in materi...
A 1975 discovery about a missing nucleotide in tumor RNA has been linked to cancer development. Researchers have found that the TYW2 gene is epigenetically silenced, causing small but aggressive tumors and leading to poor survival rates.
A team of Japanese researchers has discovered a new species of sea worm in the Southern Ocean, expanding our understanding of the region's biodiversity. The newly identified species, Flabelligena hakuhoae, is one of six described species within the genus Flabelligena.
New research from Duke University reveals that Black women with natural hairstyles are perceived as less professional and less likely to get interviews. The study found that biases against natural hair can perpetuate race discrimination in the workplace.
Researchers at UT Southwestern Medical Center discovered that depleting the key protein Reelin can protect against multiple sclerosis symptoms and promote recovery. By reducing monocyte adhesion on blood vessel walls, Reelin levels may be a novel way to treat MS.
The study found that democratic countries tend to copy each other's decisions, while the timing of implementation is crucial in containing the spread. The researchers conclude that political decisions during the pandemic were influenced by internal pressure and a desire for decisiveness.
Researchers propose a treatment paradigm targeting leukotrienes, which play a key role in severe COVID-19 cases. The proposed combination of zileuton and montelukast could help reduce inflammation and prevent pulmonary edema.
A recent study by Norwegian University of Science and Technology researchers Roger Andre Søraa and Eduard Fosch-Villaronga calls for exoskeleton designers to consider inclusivity in their designs. The goal is to make the technology accessible to a broader range of users, including those with different heights, weights, and genders.
A study published in Neuropsychopharmacology found that the balance between glutamine and glutamate levels in the nucleus accumbens is crucial for sustained effort-based motivated performance. The research suggests a potential link to therapeutic strategies, including nutritional interventions, to address motivational deficits.
A new study estimated that COVID-19 was widespread in Wuhan, China, and Seattle, Washington, weeks before lockdown measures were implemented. The researchers found that there could have been over 12,000 undetected symptomatic cases of COVID-19 in Wuhan.
A new study published in the Journal of Transport and Health found that walking to work can significantly improve a person's self-rated health compared to casual strolls. People who walked primarily for utilitarian purposes, such as commuting to work, reported better health than those who walked mostly for leisure.
Researchers found that strong anxiety about outcomes from new products can enhance consequential adoption intentions and actual adoption, especially when combined with strong hope. This effect is due to action planning, which boosts perceived control over outcomes and leads to increased product satisfaction.
A team of researchers has created a new family of inks that can print electronic devices with unprecedented scales. The ink formulation overcomes the coffee ring effect, allowing for uniform thickness and properties in printed shapes.
A team of scientists from UC San Diego identified a metabolic switch that decreases tumor growth in mice by restricting dietary amino acids. They found that restricting serine and glycine led to the production of toxic lipids that slow cancer progression.
A study published in The FASEB Journal identifies a protein encoded by SARS-CoV-2 that may facilitate the virus's quick spread through cells. The research highlights key characteristics of the virus that could aid in the development of treatments for COVID-19.
Researchers found that single neurons' down-regulation of excitability can provide working memory for language processing. The model establishes context-dependent and serial order-sensitive memory, ideal for language comprehension.
A new study finds that Front-of-Pack labelling on food products leads to a reduction in the quantity of labelled store-branded food purchased and an overall improvement in nutritional composition of consumers' shopping baskets. The study, published in the Journal of Health Economics, shows significant improvements in poorer households.
Hurricane Elida's eye has become fully covered by high clouds, a sign of the storm weakening due to cooler waters. The storm is expected to weaken quickly and degenerate into a remnant low-pressure area on Thursday.
A team of archaeologists uncovered evidence of the oldest direct cremation in the Middle-East, found in a pyre pit in Beisamoun, Israel, dating back around 9,000 years. The remains indicate a shift away from traditional burial practices towards shorter rituals.
Research reveals that lower-income families experience reduced memory and language abilities in children due to smaller anterior hippocampus development. The study also suggests that higher income thresholds beyond $75,000 may not provide additional cognitive benefits.
A team of scientists from Hokkaido University has successfully developed an adsorption-extraction technique to efficiently detect SARS-CoV-2 in untreated wastewater. This breakthrough method, using a surrogate virus like murine hepatitis virus, offers a fast and economical way to track the spread of COVID-19 at a larger scale.
Researchers at DOE's Princeton Plasma Physics Laboratory have developed a model that accurately reproduces the conditions for ELM suppression in the DIII-D National Fusion Facility. The model predicts wider operational flexibility for tokamaks, enabling enhanced fusion reactor operation and expanding the capabilities of fusion devices.
This observational study found a significant prevalence of lupus anticoagulant (LA) positivity among patients with COVID-19, indicating a potential link between LA and severe disease outcomes. The study's findings suggest that monitoring for LA positivity may be crucial in managing COVID-19 patients.
A new study found that five different types of seafood - oysters, prawns, squid, crabs, and sardines - contain plastic, with varying levels of pollution. The research used a newly developed method to identify and measure five different plastic types, revealing surprising differences in the amount of plastic present among species.
Researchers at the University of Groningen have developed a new class of proton-conducting polymers based on protein-like materials, which may be useful in future bio-electronic devices and sensors. The novel material has shown higher measured proton conductivity than any previously known biomaterials.
Research by University of Illinois experts links industry concentration to lower wages and benefits for workers in buyer-constrained industries. The study reveals that market constraints reduce economic surplus available for union bargaining, curbing wages and harming job quality.
New research reveals that ocean warming patterns will increasingly be influenced by atmospheric warming, making them easier to predict. This suggests a significant shift from past climate models, which struggled to simulate ocean warming.
A study published in PLOS ONE has uncovered the oldest known cremation site in the Near East, dating back to 7013-6700 BC. The remains of a young adult found in Beisamoun, Israel, show evidence of intentional cremation, suggesting a cultural shift in funeral practices during this period.