Researchers at Oregon State University have found that the order of microorganisms colonizing plants has a significant impact on microbiome composition and disease susceptibility. This discovery could provide farmers with important tools to combat plant diseases and maintain crop diversity.
A $3 million project aims to uncover the extent and timing of Greenland's ice sheet meltdowns, informing predictions of sea level rise. Scientists will recover samples from basal ice and sub-ice bedrock, shedding light on the past and future stability of the Greenland Ice Sheet.
A large international study found that starting dialysis early in critically ill patients with acute kidney injury did not reduce mortality after three months. The accelerated renal-replacement therapy strategy did not show significant difference in survival between the two treatment approaches.
Researchers found the AZIN1 gene associated with metastatic prostate cancer, with reduced expression leading to fewer metastases. Further investigation is needed to confirm findings in all prostate cancers.
Researchers found that CBD can help reduce cytokine storm and excessive lung inflammation caused by COVID-19. The study suggests that CBD may enable lungs to recover from damage, potentially reducing the need for mechanical ventilation.
A simple laboratory test, the eosinophil count from a routine complete blood cell count (CBC), can aid in early diagnosis and provide prognostic information for COVID-19 patients. Persistent low counts correlated with poor prognosis and high disease severity.
A team of researchers has developed a potential approach to overcome anti-VEGF resistance in patients with age-related macular degeneration. By combining apolipoprotein A-I binding protein (AIBP) with anti-VEGF, the strategy effectively suppresses choroidal neovascularization (CNV) and reduces drug resistance.
Research on heat-stressed gestating dairy cows found negative effects on the productivity and health of their female offspring, including reduced milk yield, length of productive lifespan, and increased rates of illness. These impairments translate to considerable annual costs to US dairy producers.
Research from NC State University reveals how MutL and MutS proteins create an immobile structure to prevent replication errors, reducing errors by a thousand-fold. The complex also prevents mismatched regions from being packed back into the cell during division.
A new international research project aims to evaluate the impact of alcohol control policies on morbidity and mortality in Lithuania and other Baltic states. The study, led by CAMH and the Lithuanian University of Health Sciences, will investigate the effectiveness of policy interventions implemented between 2016 and 2018.
A peer-reviewed study published in Science finds that 18-22% of Brazil's annual soy exports to the European Union are potentially contaminated with illegal deforestation. The study identifies specific producers responsible for 'poisoning the barrel' and estimates greenhouse gas emissions from deforestation-linked soy and beef exports.
New research reveals that children's paintings contain valuable insights into their cognitive development, spatial relationships, and artistic abilities. Digital image analysis technology helps identify areas of improvement in art education, such as focusing on object size, composition, and creative methods.
The rapid adoption of telehealth services during the COVID-19 pandemic has raised concerns about care quality and safety. Experts warn that integrating essential components of traditional doctor visits into virtual care poses challenges, including physical exams, lab work, and imaging. However, telehealth also holds promise for improvi...
A Rutgers study surveyed 134 college students of color and found that 90% observed police brutality videos, leading to symptoms of post-traumatic stress disorder, anxiety and fear of future police encounters. Researchers emphasize the need for police reform to stop killings of Black men, women and children.
Experts say mask requirements protect workers at retail stores and restaurants from COVID-19. Mandatory mask-wearing could normalize in the US like it has in east Asia.
Researchers identify a protein called BafA produced by bacteria that induces angiogenesis in human endothelial cells, leading to the formation of new blood vessels and lesions. The discovery opens new possibilities for studying angiogenesis and developing diagnostic and therapeutic strategies for bartonellosis.
The American Thoracic Society has published a guidance document to help clinicians restore elective in-person pulmonary and sleep services. The guidance provides recommendations for resuming services, prioritizing patients, and implementing infection control measures to mitigate the risk of viral transmission.
Scientists at the University of Münster developed a new method to construct complex polyenes, such as retinoic acid, using small molecules as
Medical ethicists warn against premature COVID-19 triage, citing concerns over fairness and strain on patients and medical personnel. The experts advocate for increased regional, national, and international collaboration in intensive care to avoid shortages.
Researchers have identified key agronomic traits for high yield in short-duration rice, which can enhance source capacity during grain filling. The new breeding lines yielded 11-38% higher than the most popular short-duration variety, indicating enormous potential for developing improved varieties.
A new randomized trial published in Annals of Internal Medicine found that hydroxychloroquine showed no benefit in reducing symptom severity or duration in outpatients with early, mild COVID-19. The study suggests that the treatment may not be effective in populations at higher risk for severe COVID-19.
A pre-brain surgery test using navigated repetitive transcranial magnetic stimulation (nrTMS) accurately maps language centers in patients with brain tumors not involved in these areas. The method's accuracy varies depending on tumor involvement, but it shows promise for improving surgical planning and patient outcomes.
A mathematical modelling study finds that a delay of three days or more between symptom onset and testing will not reduce onward transmission sufficiently to control further spread. Contact tracing strategies must keep the R number below 1, and mobile apps can speed up this process.
Researchers found severely limited exercise capacity in adults with type 2 diabetes, increasing risk of heart failure. Subtle impairments in blood flow and heart function were detected using advanced imaging techniques.
Researchers have discovered a compact Cas protein, CasΦ, in megaphages, which could make gene editing easier and more efficient. This protein targets specific regions of DNA with high accuracy and can cut both single-stranded and double-stranded DNA, making it a promising tool for crop improvement and disease treatment.
A study of 9,029 adults found that cystatin C-based kidney function was associated with lower odds of frailty, falls, and cardiovascular disease events. The difference between cystatin C- and creatinine-based kidney function could be used to predict adverse outcomes in older adults.
Dr. Lewis A. Lipsitz outlines his vision for a healthy longevity at 84, emphasizing the need for social connections, sense of purpose, and accessible healthcare. He envisions multigenerational communities with technology-enabled support, affordable housing, and community-based health services.
A new male fertility test, Cap-Score, has been developed to predict which men need treatment and which couples might have success with different forms of assisted reproduction. The test quantifies sperm capacitation ability, enabling doctors and couples to make informed decisions about their fertility.
An international team of physicists has analyzed comprehensive data from over a dozen subatomic experiments to investigate right-handed neutrinos. The analysis reveals significant challenges in detecting these particles, but also suggests a possible connection to dark matter.
Researchers have developed graphene-based sensors that retain adsorbed gas molecule interactions hours after electric field is turned off, enabling long-term molecular identification and 'beyond-sensing' applications.
Researchers used femtosecond laser direct write technology to simulate curved space-time near a black hole. They observed accelerated single-photon wave packets and fermion pairs escaping the black hole, mimicking Hawking radiation. This experiment demonstrates the potential for quantum simulation in studying general relativity.
The US Department of Energy has awarded Penn State over $10 million to develop new ferroelectric memory materials that can be stacked in the third dimension above processor chips. This breakthrough technology aims to mitigate the von Neumann bottleneck, allowing for seamless communication between memory and computation.
A study found that non-white patients with COVID-19 have more severe disease on chest X-rays, increasing the likelihood of adverse outcomes. Limited English proficiency and socioeconomic factors contribute to these disparities.
Scientists have discovered a compound in the American beautyberry leaves that works in combination with oxacillin to knock down resistance to the drug methicillin-resistant Staphylococcus aureus, or MRSA. The study suggests a new potential therapy for treating antibiotic-resistant infections.
A researcher at Northeast Ohio Medical University has received a large federal grant to develop the first human treatment for tinnitus, a debilitating hearing impairment affecting millions of people in the US. The grant aims to create a drug to treat and prevent tinnitus, which currently has no available treatment options.
A decision support system within the EHR system significantly increased provider awareness of CKD among primary care providers. The study demonstrated that implementation of such a system can lead to improved processes of care, including blood pressure management and medication prescribing.
Researchers at the University of Alberta and Universidad Autónoma de Zacatecas developed a new method to analyze urinary metabolome in healthy newborns. The study provides reference data for 86 previously unmeasured chemicals in newborn urine, enabling more accurate diagnoses.
Researchers develop sensitive optical fiber sensors using D-A based aggregation-induced emission (AIE) molecular rotors and one-dimensional polymer fibers. The sensors respond to ambient humidity rapidly and reversibly with observable chromatic fluorescence change.
Researchers from the University of Warwick analyze sedimentary ancient DNA from Doggerland, revealing insights into a 8150-year-old tsunami and its impact on the region. The study develops new methods for authenticating ancient DNA, including metagenomic assessment methodology.
Researchers have developed a method to reduce noise and resources required for quantum information transmission, paving the way for a quantum internet. Quantum multiplexing allows for the combination of multiple pieces of information into one photon, reducing the need for separate stamps and enabling significant resource reduction.
Researchers found that sea turtles do not arrive at their targets with pinpoint accuracy, but can make course corrections in the open ocean. They use a crude true navigation system, possibly using the earth's geomagnetic field, to guide them on their way.
Researchers at the University of California, Irvine have discovered a key mechanism in breaking down nitrogen gas, a crucial step towards developing more efficient and sustainable methods. The breakthrough could lead to cheaper and more energy-efficient ways to produce fertilizers and alternative fuels.
Certain decontamination methods for reusable N95 face masks can significantly impair their effectiveness. Research found that treatments using high concentrations of gas plasma hydrogen peroxide or longer processing times degrade filtration performance. In contrast, vaporized hydrogen peroxide sterilizers and shorter decontamination cy...
Scientists have discovered a potential new target for treating Ewing sarcoma, a childhood cancer that affects the bone and soft tissue. The researchers found that an imbalance in genetic code-reading machines causes nucleoli to break up into smaller entities in Ewing sarcoma.
The research team created better climate model simulations that predict variation in monsoon rainfall the following season, with improved forecasts for the Indian subcontinent. The new model uses complementary satellite data to quantify the connection between snow pack characteristics and monsoon strength over the Asian monsoon region.
A new hypercompact CRISPR enzyme, CasΦ, has been discovered in huge bacteriophages and provides a powerful tool for genome editing. It can target a wider range of genetic sequences than current CRISPR-Cas proteins, making it a promising alternative for cellular delivery.
Researchers at Lehigh University have developed a hydrogel material that can degrade and re-form in the stomach, protecting oral drugs from acidic environments. The gel, called covalent adaptable hydrogels (CAHs), could revolutionize oral drug delivery by targeting specific areas of the intestine.
Researchers at Rutgers University have created ultra-small nanoparticles that exhibit unusual blinking behavior, which could help produce methane and other fuels. The crystals, composed of titanium dioxide, stay charged for tens of seconds, enabling potential applications in environmental cleanups, sensors, and electronic devices.
Researchers tracked green sea turtles migrating long distances in the Indian Ocean to small oceanic islands, revealing that they can redirect in the open ocean at a crude level. The study provides evidence of a map sense with open ocean reorientation, allowing turtles to fine-tune their navigation.
A new study by University of Alberta biologists found that female mountain pine beetles use different strategies to find success, regardless of distance traveled. Those flying longer distances tend to lose weight but produce more pheromone, increasing their chances of attracting fellow beetles.
Researchers developed a simple agglutination assay to detect COVID-19 antibodies in plasma samples within 20 minutes. This test can identify recent cases and aid clinical trials, with potential for widespread use in high-risk countries.
Researchers have successfully created supramolecular poly-catenanes through molecular self-assembly, forming hierarchical structures composed of interconnected rings. The nano-poly[n]catenanes exhibit unprecedented physical properties and potential applications in molecular machines and active materials.
A GW-led research team is investigating HIV-1 resistance to antibody treatments, aiming to develop effective combination therapies for treatment, prevention, and potential cure. The project, funded through April 2025, aims to identify effective combination antibody cocktails that limit the virus's ability to escape from antibody pressure.
Dien Nguyen investigates nucleon interactions at short distances in both heavy and light nuclei during her fellowship. Her research will expand on previous findings, providing insights into neutron stars and the behavior of protons and neutrons inside atomic nuclei.
A study published in Educational Evaluation and Policy Analysis found that institutions included in the College Affordability and Transparency Center lists did not change their pricing policies or students' enrollment decisions. The findings suggest that relying on students to seek out affordability information is unlikely to influence...
Novilytic, a Purdue University-affiliated bio-analytics startup, has received a $1.4 million Phase II SBIR contract to continue developing its Proteometer instrument technology for pharmaceutical antibody manufacturers. The technology allows process chemists and engineers to monitor and control antibody purity in process.
Research published in BMJ Global Health suggests that oral herpes rates are falling among European children and young people. The prevalence of the virus is declining by 1% per year, with more than two-thirds of the population testing positive for HSV-1, but risks increasing sexually in adulthood.
The Chan Zuckerberg Initiative provides $1.3 million in funding to NORD and EURORDIS, supporting organizational capacity building and Rare Disease Day awareness campaigns. The grants aim to unite and improve the lives of over 350 million people living with rare diseases worldwide.
Wolfram Syndrome is a progressive degenerative disease characterized by diabetes, psychiatric symptoms, loss of vision, deafness, and incontinence. Yale researchers have discovered a potential treatment involving two existing drugs that restore calcium signaling and improve cell functions.
A team of scientists at the Chinese Academy of Sciences has discovered a new, very short-lived isotope of neptunium, confirming the existence of the N = 126 shell in Np isotopes. The study used alpha-decay spectroscopy to identify the new isotope, which was produced through fusion reactions.