Articles tagged with Evolutionary Genetics
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers found that many genes inherited from Neanderthals interact with modern-day viruses like HIV and influenza A, suggesting they provided protection against ancient RNA viruses. The study suggests a 'poison-antidote' model of gene swapping between species, where Neanderthals bequeathed genetic tools to combat invaders.
Researchers found a new dynamic between mother's genome and their offspring's genome influencing development and adaptation to ecological conditions. Genetic mismatches can hinder adaptation in some species.
A study on Asian ladybird beetles reveals a single gene, pannier, that regulates diverse color patterns. The gene's expression affects black and red pigmentation in the forewing, driving morphological evolution.
Researchers have confirmed that genome duplication drives the evolution of polyploid plant species, such as Arabidopsis kamchatica. The study found that the double genome allows for advantageous genetic mutations and increased adaptability to environmental conditions.
A new USC Dornsife study finds that genes can help an organism survive, rather than just being a negative trait associated with aging. This challenges the long-held hypothesis of 'antagonistic pleiotropy', which suggests that genes that enhance reproduction contribute to aging.
A study led by Prof. Erich Bornberg-Bauer revealed that de novo genes constantly emerge in non-coding DNA regions and can occasionally acquire functions in organisms over longer periods of time.
Researchers discovered that mice lacking a key gene, CMAH, can run stronger and longer with less fatigue. This gene loss may have contributed to humanity's ability to run long distances relatively tirelessly.
A UTA doctoral student has received a Graduate Research Fellowship Program grant to fund her research on genetic variation in whiptail lizards and its impact on the microbiome. The award will support her three-year research project using both sexually and asexually reproducing species living in sympatry.
Researchers have identified key genetic changes that occur during colorectal cancer development, including 'chromosomal catastrophes' that lead to tumour growth and diversity
Researchers at University of Colorado Boulder develop Controlled Hindrance of Adaptation of OrganismS (CHAOS) approach to disrupt gene expressions in bacteria, effectively stunting their ability to evolve defenses. The method offers a sustainable long-term solution to combat antibiotic-resistant superbugs that infect nearly 2 million p...
Scott Juntti, UMD professor, develops genomic tools for testing genes' impact on organism traits in cichlid fish. The goal is to predict an organism's phenotype by understanding the sets of rules that govern genetic variation.
Researchers are studying the genetic basis of carnivorous plant evolution, seeking to understand how similar traits emerge in different orders. Dr. Kenji Fukushima's work aims to develop new molecular tools for analyzing specific genes in carnivorous plants.
Research by an international team from the University of Vienna reveals that remote islands have higher numbers of non-native species, which can lead to extinction events and threaten unique island species. The study found that isolation from the mainland increases the number of non-native species, while native species decline.
A newly-discovered fossil turtle, Eorhynchochelys sinensis, lived 228 million years ago with a beak but no shell. This find sheds light on the evolution of turtles and challenges traditional theories, supporting mosaic evolution and shedding new light on turtle ancestry.
New research reveals that female mosquitoes rapidly evolve more selective mating behavior when faced with existential threats from other invasive mosquito species. This adaptation is driven by genetic changes in specific gene regions and enables them to avoid sterility caused by interbreeding with male males of a different species.
A study found that long, noncoding stretches of DNA in a calcium transport gene may predispose individuals to schizophrenia and bipolar disorder. These 'hidden variants' could help identify patients at risk and tailor treatments.
Researchers at the University of Texas at Dallas have developed a statistical method to analyze millions of RNA structures, enabling them to predict functional interactions. This breakthrough aims to prevent toxic relationships between molecules that lead to disease, and potentially improve human health.
Researchers found that periwinkles have developed a genetic toolkit with specific genes clustered on three chromosomes to help them adapt to environments threatened by crabs and waves. This rapid adaptation is thought to have occurred within 5,000 generations, enabling the snails to survive in rapidly changing coastal habitats.
The study of Flores pygmy humans shows they have Neanderthal and Denisovan ancestry, but no direct link to Homo floresiensis. The short-statured phenotype is a result of recent polygenic selection on standing genetic variation.
Researchers found that modern pygmy genomes showed no evidence of gene flow from the extinct 'hobbit' species, contradicting previous expectations. However, they did find genetic variants associated with short stature and dietary adaptations in genes involved in fatty acid metabolism.
Rice University's Luay Nakhleh has received $1.5 million in grants from the NSF to develop algorithms that can infer evolutionary histories of tumor cells, helping researchers understand why some cancer cells spread and mutate differently.
Researchers identified 27 unique amino acid replacements in 27 different proteins of hot-spring snakes, which were associated with functions like immunity and DNA repair. These mutations enable the snakes to thrive under extreme conditions such as intense radiation and hypoxia.
A team of researchers has discovered a new species of Placozoa, a phylum of simple multicellular animals, by analyzing its genetic makeup. The study, published in PLOS Biology, used taxogenomics to describe the new species, which was previously thought to be a single species, Trichoplax adhaerens.
A new species of round fungus beetle was discovered in Malaysian Borneo with remarkably long genitalia. The species was named after actress and biologist Isabella Rossellini due to its unique reproductive characteristics, showcasing an evolutionary 'sexual arms race' between males and females.
Researchers found that different types of efflux pump proteins, key to antibiotic resistance, may not have evolved from a common ancestor. Instead, they may have developed independently through convergent evolution, offering new insights into fighting drug-resistant superbugs.
Researchers at Ohio State University found that unisexual salamanders rarely borrow DNA from other species, despite persisting for millions of years. The study suggests that their unique reproductive strategy may be linked to environmental changes or specific interactions with other species.
A study found that bats have preserved a viral gene from an ancient Ebola-like virus for millions of years. The VP35 gene helps regulate the immune system and may play a role in preventing disease in bats.
A study found that variations of a single gene in pigeons are associated with diverse feather patterns and unexpected links to human vision defects. The gene, Norrie Disease Protein, is well-studied in humans but has different effects on pigs, causing only pigmentation changes.
A new AI framework, ExPecto, predicts the effects of genetic mutations in the 'dark matter' regions of the human genome. The framework pinpointed mutations potentially responsible for increasing the risk of several immune-related diseases, including chronic hepatitis B virus infection and Crohn's disease.
Scientists discovered that polyps of the marine hydrozoan Ectopleura larynx allow genetically unrelated individuals to fuse their bodies and share skin and stomachs. This unique behavior provides survival advantages in a competitive ocean environment.
Human ancestors were scattered across Africa, with diverse habitats and shifting environmental boundaries leading to a staggering diversity of human forms. The mixing of these populations ultimately shaped our species.
Researchers decipher how plants evolve recognition systems to prevent self-fertilization, leading to genetic diversity in nature. The study found that new mating types can evolve through different pathways and are influenced by population demographics and mutation rates.
Researchers used genetic analysis to sort bat species, revealing two new species in Kenya. The findings have implications for conservation and farming efforts.
Researchers found that evolutionary changes occur deep in the fly brain, in a small cluster of neurons controlling mating behavior. The study overturned long-held beliefs about how evolution ensures animals perpetuate their species.
UCSF researchers identified key genetic changes that transform benign moles into malignant melanoma, including mutations in DNA regulatory genes. They used CRISPR to recreate the steps of melanoma evolution in lab cells, revealing new biomarkers and potential targeted therapies.
A study published in BMC Evolutionary Biology found that Bale monkeys living in different habitats have distinct mitochondrial DNA profiles. The researchers discovered that populations from fragmented forests were more closely related to vervet and grivet monkeys than those from continuous forests, suggesting hybridization had occurred.
A recent study reveals that the fastest rates of species formation occur at high latitudes and in cold ocean waters, contradicting the long-held assumption that tropical environments are evolutionary hot spots. The research found that cool-water and polar ocean fishes formed new species twice as fast as average tropical fish.
The study analyzed 71 placental mammalian species and found that the genes RXFP2 and INSL3 were either lost or nonfunctional in four Afrotherian species, indicating a more recent origin of testicular retention. This suggests that molecular vestiges can be used to reconstruct evolutionary changes in body parts.
A study of nearly 4,000 extremely old Italians found that mortality rates plateau after 105 years old, with people between 105-109 having a 50/50 chance of dying within the year and an expected further life span of 1.5 years. The findings challenge previous research on a final cut-off point for human lifespan.
The study uses DNA sequence data to analyze the evolution of testes in mammals, finding that African species lack the testicular descent process due to non-functional genes. This suggests that the testicular descent process was ancestral and lost in these species.
A recent study has identified 246 candidate genes involved in dog domestication, which influence brain function, development, and behavior. The research suggests that changes in these genes may have contributed to the evolution of dogs from wolves, making them more active during the day rather than at night.
A fossil of a banana-eating bird ancestor was found in North America, dating back 52 million years. The discovery suggests these birds once thrived outside the tropics, with long legs indicating they may have been ground-dwelling.
Researchers developed a new genetic engineering technique to improve an enzyme's ability to break down biomass. The EASy method enables accelerated evolution of desirable traits in microorganisms, leading to more efficient conversion of lignin into fuels and plastics.
Researchers found that expanding gene-regulatory modules can give rise to new traits, such as the enlarged snout in African cichlid fishes. The study implicated key genetic pathways, including the Tgfβ-Scx pathway and Adam12 protein.
A new study reveals that RNA changes played a crucial role in the domestication of sunflowers, allowing for rapid evolutionary transformation over 5,000 years. The researchers identified key genes and regulatory mechanisms involved in alternative splicing, which created useful efficiencies but also introduced variation.
A new study led by the NIH identified roles for over two dozen genes shared with humans, many linked to human eye disorders, in causing cavefish blindness. Epigenetic regulation mechanisms have been found to play a key role in this process.
A study analyzing ancient Icelandic genomes of 25 individuals from the island's colonization period (870-930) found that present-day Icelanders have a 70% Norwegian genetic fingerprint. The analysis also revealed a gender bias in the population, with men of Scandinavian origin having more offspring than women of Celtic origin.
A team of researchers has developed a model that simulates protein evolution, revealing how evolving protein components can give rise to dynamic and efficient molecular machines. The model shows that flexibility allows proteins to bind effectively to other molecules.
Cavefish have higher levels of DNA methyltransferase DNMT3B in developing eyes, leading to epigenetic suppression of eye development genes. This process differs from genetic mutations, which are permanent changes in the DNA code.
A genetic algorithm developed by Spanish researchers accurately predicted the vertical growth of Tokyo's Minato Ward, predicting the number and locations of future skyscrapers. The study suggests that evolutionary computation can identify hidden patterns in urban systems and predict possible city evolution scenarios.
Mongooses learn lifelong habits from escort animals rather than their genetic parents, according to University of Exeter researchers. This cultural inheritance helps maintain diversity within groups, contradicting expectations that it would lead to uniformity.
A team of scientists discovered that genetic diversity in host populations slows down the adaptation of parasites, increasing their resistance to disease. This finding has significant implications for ecosystem research and the preservation of biological diversity.
Researchers found that mechanical cues contribute to the regulation of gene expression during early development. External pressure can activate or restore the expression of a crucial developmental regulator gene, brachyury. This mechanism is conserved across species, including zebrafish and fruitflies.
A study found that genes beneficial in youth but detrimental in old age may contribute to the rise of chronic diseases in modern societies. The review suggests that natural selection may be changing course, but more research is needed to fully understand its impact on human health.
Researchers discovered a genetic signature in Nasonia wasps that suppresses Wolbachia bacteria transmission to eggs, giving the wasp an evolutionary benefit. This finding provides insight into how animals may evolve to control their transmitted bacteria, highlighting unique defense strategies across species.
Researchers aim to identify genetic markers that can predict tumor response to radiation therapy, leading to more personalized treatment approaches. The goal is to improve treatment responses, reduce toxicity, and enhance quality of life for cancer survivors.
A comprehensive genomic database for fishes has resolved evolutionary relationships among 131 species, including tuna and seahorses, and identified genetic markers to track divergence through time.
Researchers at Michigan State University have identified how MRSA absorbs human fatty acids to resist antimicrobials, providing a new target for developing more effective treatments. By inhibiting the cell membrane's ability to produce lipids, scientists may improve the efficacy of existing antibacterial agents like triclosan.
In a breakthrough study, microbes have been found to act like savvy investors when contributing to the common good. They adjust their investment strategy depending on how much they have at stake, maximizing returns in groups with mostly relatives and exploiting contributions in outnumbered groups.
Researchers discovered a genetic variant associated with migraine headaches that is more common in people living in colder climates and higher latitudes. This variant may have helped early humans adapt to the cold, contributing to its high frequency in European populations and higher prevalence among individuals suffering from migraines.