Articles tagged with Evolutionary Genetics
Researchers propose a simple model of development that explains patterns in morphology and body plans, attributing sparseness of variety to interactions between multiple genes. The hybrid developmental-phylogenetic model reproduces fossil record patterns, including increasing variation among taxonomic groups and decreasing within.
A study by Tomislav Domazet-Lošo and Diethard Tautz reveals that most disease-associated genes originated before the first cells emerged, with only recently evolved genes showing no link to human diseases. This discovery sheds light on the evolutionary origins of genetic diseases affecting humans and other living organisms.
A recent study by American Museum of Natural History scientists clarifies the evolutionary relationships among seven sea turtle species. The researchers found that specialized diets arose independently in three distinct groups of sea turtles, with flatback and green turtles being closely related despite their differing diets.
Researchers discovered that HIV-1 group M strain began spreading among humans between 1884 and 1924. The study suggests urbanization played a significant role in the pandemic's emergence. A genetic analysis revealed evidence of common ancestor around 1900, indicating an earlier origin than previously thought.
The study reveals that growing urbanization in colonial Africa allowed the HIV virus to flourish, leading to the outbreak of the epidemic. The researchers used genetic sequencing to analyze ancient samples and found that the pandemic strain emerged around 1900.
Researchers found that polygyny leads to an excess of genetic diversity on the X chromosome compared to autosomes. The process also results in fewer unique male genes being passed into the next generation.
Yale scientists have found genetic traces of extinct Galapagos tortoise species in living populations, paving the way for potential breeding programs. The study reveals that some islands, including Volcano Wolf, are home to tortoises with DNA from both known and extinct species.
Researchers at Uppsala University used medical x-rays to find rudimentary fingers in the fins of Panderichthys, a transitional animal between fish and tetrapods. This discovery indicates that fingers evolved earlier than previously thought, contradicting the long-held theory that they emerged in tetrapods.
Researchers at Yale University identified a key regulatory link in the evolution of pregnancy involving the altered function of HoxA-11 protein. This finding revolutionizes our understanding of how pregnancy evolved in mammals, highlighting a crucial genetic switch that tempered the immune system and allowed for internal development.
Researchers at Stanford University School of Medicine discovered that lager beers originated from an unlikely pairing between two species of yeast, including the long-used ale yeast. The study found that the hybridization event occurred twice, with each partner bringing unique advantages to the match.
The Chicago Center for Systems Biology will focus on transcriptional networks, studying how multiple genes work together to regulate life's basic processes. Researchers will use complex biological models to understand gene regulation in response to environmental and genetic variation.
Researchers found a gene enhancer, HACNS1, that may have contributed to the evolution of the human opposable thumb and adaptations for walking on two legs. The discovery provides significant insights into genetic differences between humans and chimpanzees.
Researchers discover a 546-base pair element, HACNS1, that enhances gene expression in human limbs and brain, contributing to uniquely human digit patterning. The study highlights the power of conserved noncoding sequences in regulating gene expression across species.
Researchers studied the Prestin gene in echolocating bats and fruit bats, finding similarities in distantly related species. This suggests that echolocation has evolved more than once in bats, defying conventional wisdom on evolutionary relationships.
Researchers at Penn State have developed a computational method to trace evolutionary histories of proteins back to cells or viruses, aiming to settle the debate on which came first. The new approach uses phylogenetic profiles and tree-like diagrams to provide clearer insights into retroelement evolution.
A team of Wisconsin scientists has discovered how a simple genetic switch controls decorative traits in male fruit flies, shedding light on the evolution of male lion manes, bull moose antlers and peacock tails.
A new study reveals that transfer RNA's (tRNA) dual functions of reading the genetic blueprint and adding amino acids to proteins evolved independently. The findings suggest that these functions were acquired at different points in time, with protein synthesis preceding the refinement of the genetic code.
Researchers found hundreds of genes affected by bacterial partnership in a squid host, including those associated with human responses to bacteria. This discovery may change our understanding of the main purpose of the immune system.
Scientists studying bacteria at Evolution Canyon found that ecotypes on hot and cool slopes have distinct fatty acid compositions, enabling them to cope with temperature differences.
A new study by Claus Wilke and D. Allan Drummond found that genetic evolution prioritizes minimizing errors in protein production to prevent misfolded proteins, which can cause neurodegenerative diseases. The research may lead to better detection of genes with mutations leading to toxic proteins.
A Harvard University study reveals that genes have evolved to minimize protein production errors, which can cause neurodegenerative diseases like ALS. The research found that natural selection favors the development of genes that prevent misfolded proteins resulting from translation mistakes.
Researchers found that when females capture more pollen, female-determining pollen tubes out-compete male-determining ones. The team's study on Rumex nivalis in the Swiss Alps shows how demographic aspects can influence plant sex ratios.
Recent RNA research reveals new roles in regulating gene expression and structural components, with potential for creating compounds to overcome genetic disorders. The EUROCORES programme brings together European groups to collaborate on RNA quality control and its applications.
Lemur males use scent glands on their bodies to advertise fitness and family relationships, with individual scents reflecting genetic quality. Researchers analyzed chemical components in ringtailed lemur scents using sophisticated machinery.
Researchers found female red squirrels mate with related males, contradicting expected social norms. Genetic relatedness does not impact offspring survival or growth rate.
A recent study published in PLOS Genetics reveals hundreds of biological differences between male and female brains, with some differences persisting for millions of years. The findings suggest that these sex differences may have functional implications for brain function and disease treatment.
The study reveals hundreds of biological differences between male and female gene expression in the cerebral cortex, indicating a long-evolved signature of sex differences. These findings have implications for medical dosages and treatments of diseases or damage to the brain.
A new computational tool provides accurate insights into DNA and protein sequence evolution by avoiding systematic errors. The results suggest that sequence turnover is much more common than assumed, with a higher frequency of insertions and lower frequency of deletions.
Researchers suggest a new evolutionary model for male homosexuality, involving genetically-based 'sexually antagonistic selection' that promotes female fecundity. This model provides insight into the origins and dynamics of male homosexuality in human populations.
Researchers identified sequence variations in the ARP gene that allow differentiating venereal syphilis from non-venereal Treponema pallidum subspecies. The findings have significant clinical, epidemiological and evolutionary implications.
A new study investigates the evolution of genomic imprinting in mammals, finding that different regions became imprinted at different times during mammalian evolution. This suggests that changes were in response to selection pressures and are adaptive.
A new analysis of the genome of St Louis encephalitis has shed light on its evolution, tracing the virus back to South America and identifying a single mutation that made it pathogenic to humans. The research suggests that population dynamics and point mutations played a key role in the virus's adaptation to humans.
Researchers have completed the first analysis of platypus DNA, revealing insights into gene regulation and immune systems that may lead to advances in human disease prevention. The study's findings also provide new perspectives on mammalian evolution and conservation efforts.
Researchers found that female mice prefer outbred males with diverse major urinary proteins (MUPs) in their urine. This distinction allows females to 'count' the number of protein types, avoiding inbred males with less varied protein profiles.
Researchers at the American Museum of Natural History contributed to a study analyzing over 2,300 species in Madagascar to develop a more efficient conservation plan for the country's unique biodiversity. A new phylogenetic tree of multicellular animals has also been redrawn by comparing genetic data from diverse animal phyla.
A K-State biology professor is studying the evolution of the state flower, sunflower, using a $610,000 grant from the National Science Foundation. The research focuses on how environmental stress may have caused the activation of retrotransposons in hybrid species, leading to massive genomic expansion and restructuring.
Researchers discovered a preference for certain DNA letters across intron regions and the opposite preference in coding regions, affecting at least a third of the genome. This finding supports previous studies suggesting that non-coding DNA is biologically important.
A new genetic analysis by Yale School of Medicine researchers suggests that a genetic variant in East Asian populations may have protected residents from becoming alcoholics. The study found that this variant became widespread through natural selection in specific Hmong- and Altaic-speaking groups, hinting at an environmental factor.
A new study by Yale and Washington University researchers challenges the idea that complex traits have a 'cost of complexity,' suggesting that many mutations only affect a small number of traits. The team identified genomic regions affecting skeleton characteristics, revealing a well-coordinated process in tuning up complex traits.
Menopause is thought to be an evolutionary adaptation that helps minimize reproductive competition between females in the same family unit. The researchers propose that older women should cease breeding when younger women start to breed, explaining the observed timing of reproductive cessation in humans.
A recent study published in PNAS found that Spanish brown bears have genetic material from bears in other parts of Europe, challenging the idea of their isolation. The research, led by Anders Götherstam and Cristina Valdiosera, analyzed DNA sequences from prehistoric material and discovered a unexpected pattern.
Scientists at MIT have developed a mathematical approach to analyze protein patterns across species to identify natural selection in microbial evolution. By analyzing the 'selective signature' of genes, researchers can infer gene function and understand ecological shifts.
Researchers found that milk-protein genes arose in the mammalian common ancestor and preceded the loss of egg protein genes. This transition allowed mammals to feed their young via the placenta and with milk, abandoning eggs as a source of nutrition. The study provides insights into the origins of lactation and placentation in mammals.
Scientists have discovered that ants deliberately spread their offspring with 'royal' genes to avoid detection and maintain an unfair advantage in queen selection. This genetic cheating undermines the notion of egalitarianism in ant societies, revealing a complex web of conflict and cooperation.
An invasive population of the freshwater snail Melanoides tuberculata shows a tremendous amount of genetic variation for key life-history traits, allowing for large potential for evolutionary change. This diversity can arise from multiple invasions and amplification through sexual reproduction.
The International Giant Panda Genome Project aims to sequence and assemble the giant panda's draft genome within six months. The project will aid in understanding the genetic and biological underpinnings of this unique species, informing conservation efforts and advancing sequencing technology.
A new study found that chickens have a different version of a gene that codes for white skin, but the yellow-skin variant is present in a completely different wild species, grey junglefowl. This discovery contradicts Charles Darwin's theory that all chickens came from a wild red junglefowl species.
Researchers found that genetic reassortment events led to the creation of new hybrid viruses in humans during severe influenza epidemics in 1947 and 1951. This challenges the standard model of human influenza virus evolution, suggesting a more complex co-circulation of multiple forms of the same strain.
Psychologists Agneta Herlitz and Jenny Rehnman found significant sex differences in episodic memory, favoring women. Women excel in verbal episodic memory tasks and are better at remembering faces, especially of females.
Researchers have speculated that the Foxp2 gene is linked to language ability, but MIT's Robert Berwick argues this connection is unlikely due to complexity and speculative chain of events. Language is likely the result of a subtle interplay among various factors, making direct genetic connections impossible.
A new study using molecular genetic data confirms that modern birds originated more than 100 million years ago, contradicting earlier fossil-based estimates of around 60 million years ago. The analysis suggests that both the fossil record and molecular clock methods have limitations in dating biological events.
Researchers discovered a significant amount of variation in genetic recombination events among individuals, with some hotspots being used more by one sex. The study found heritable differences in recombination rate and hotspot use, which could provide insights into the evolution of recombination rates.
A Penn State University research team investigated the simultaneous effects of numerous factors on microsatellite mutability, finding that repeat number, length, and composition are significant predictors. The study has applications in medical genetics, forensics, and conservation genetics.
Genes have been found to recognize similar patterns of chemical bases without physical contact, shedding light on the process of homologous recombination. This ability could explain how genes group together to perform key processes involved in species evolution.
Researchers at Fred Hutchinson Cancer Center discovered that rapid evolution of protein ZAP is associated with increased antiviral activity in humans. The longer human ZAP protein isoform has higher antiviral activity against various viruses, including alphaviruses and filoviruses.
Researchers found that a protein produced by an immunity gene called ZAP has increased antiviral activity in humans, linked to evolutionary changes. The study suggests that studying evolutionary biology and virology can accelerate the discovery of viral-defense mechanisms.
Researchers have developed a method to measure the reproductive value of female side-blotched lizards, revealing that large clutches are associated with increased survival rates. Male lizards also exhibit improved survival with small clutch sizes due to hormonal changes, highlighting an 'ontogenetic conflict' between the sexes.
Researchers found that dark coat color is linked to genes reducing fitness, contradicting Darwin's theory. The study reveals that light-coated sheep have higher reproductive success despite being smaller.
A recent study has found that human genes have evolved additional safeguards to boost the p53 regulatory network's ability to guard against DNA damage. This enhancement is thought to be linked to humans' increased need for coordinated control of molecular repair activities during DNA replication.
Researchers successfully switched a gene regulatory element from a bat to a mouse, resulting in abnormally long forelimbs. This study demonstrates that evolution can be driven by changes in gene expression patterns, rather than solely genetic changes.