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Next generation genetics technology developed to counter the rise of antibiotic resistance

Researchers developed a novel CRISPR-based technology called pPro-MobV that can remove antibiotic-resistant elements from bacterial populations. The new tool uses gene-drive thinking and has the potential to combat antibiotic resistance in healthcare settings, environmental remediation, and microbiome engineering.

SourceUniversity of California - San Diego·Journalnpj Antimicrobials and Resistance·TypeExperimental study·DateFeb 6, 2026

Curiosity- driven experiment helps unravel antibiotic-resistance mystery

Researchers have discovered a complex mechanism that allows bacteria to build resistance to antibiotics, involving a KorB-KorA regulatory system. This finding offers a fresh insight into long-range gene silencing in bacteria and provides a potential target for novel therapeutics.

SourceJohn Innes Centre·JournalNature Microbiology·TypeExperimental study·DateJan 23, 2025
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Successful construction of eukaryotic plasmids containing HBV C genotype

Research team constructs eukaryotic plasmids containing HBV C genotype and lamivudine-resistant sequences, providing an experimental basis for in vitro studies on HBV lamivudine-resistant mutants. The results contribute to understanding the mechanism of HBV lamivudine-resistance.

SourceWorld Journal of Gastroenterology·JournalWorld Journal of Gastroenterology·DateSep 24, 2008