Articles tagged with Gene Identification
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers have identified a new breast and ovarian cancer susceptibility gene, RAD51C, in a German study. The gene is associated with a high risk of breast and ovarian cancer, particularly in familial cases.
A new method has been developed to identify genetic mutations in active genes, enabling studies of disease effects and improving diagnostic accuracy. This technique allows researchers to study specific cellular processes and identify minority cells in tissue samples.
Researchers found that bees with artificially reduced insulin receptor substrate (IRS) in abdominal fat cells preferred pollen over nectar. This suggests an alternative mechanism for insulin's impact on eating behavior beyond the brain.
Researchers at EMBL identified almost 600 human genes involved in mitosis through high-throughput imaging and computer analysis. The study provides a rich resource for scientists to investigate the molecular workings of cell division.
A new study proposes that slow-growing animals waste energy in two ways, making too much protein and then discarding excess. Fast-growing oysters, on the other hand, are more efficient at protein production, according to USC marine biologists.
Researchers have discovered a gene linked to a newly recognized multisystem autoimmune disorder affecting Amish children, characterized by chronic diarrhea, enlarged organs, and developmental delays. The ITCH gene plays a crucial role in regulating the immune system, and identifying it may lead to effective treatment for these children.
Researchers at CSIRO Australia have successfully produced hand-drawn threads of artificial honeybee silk, rivalling the strength of natural silk. The breakthrough is a significant milestone towards developing biomimetic materials for various industries.
Researchers identified a link between aging and abnormal gene expression patterns in schizophrenia patients, suggesting that age-related aberrant regulation of developmental genes may explain the manifestation of the disease. The study supports early intervention and treatment tailored to the patient's age.
Researchers found similar connectivity between genes in normal individuals and schizophrenia patients, but a significant link between aging and gene expression patterns was discovered. Age-related aberrant regulation of developmentally related genes might explain at least part of the manifestation of schizophrenia.
Researchers at IRB Barcelona have identified a new gene, DOR, that facilitates the formation of autophagosomes and plays a crucial role in the cellular recycling program. The study suggests potential avenues for developing new therapies for cancer and neurodegenerative diseases by modulating autophagy.
Researchers have identified a gene, Kir2.6, underlying the rare genetic disease thyrotoxic hypokalemic periodic paralysis (TPP), which causes temporary muscle paralysis. The finding, published in the journal Cell, illustrates how investigations of rare genetic diseases can drive insights into more common ones.
A recent study published in Political Research Quarterly found that genetics may contribute to an individual's political party identification, challenging the long-held assumption that it is solely shaped by socialization factors. The study used quantitative genetic models to examine the sources of party identification and intensity.
A team of researchers has identified 12 genetic variants in the HSPB7 gene associated with heart failure. The study found a block of 12 genetic variants linked to heart failure in a large group of individuals.
A new study published in the Journal of Periodontology found that nearly 30% of human genes are expressed differently during gingivitis onset and healing. Biological pathways associated with immune system activation were identified as critical to controlling the body's reaction to plaque build-up.
Researchers developed a genetic screen for human cells to pinpoint specific genes and proteins used by pathogens. The study identified new genes essential for host-pathogen interactions, including those involved in diphtheria and E. coli infections.
This study found that variations in plasma glutamyl transferase (GGT) and albumin (ALB) levels are genetically influenced and correlate with cardiovascular disease risk factors. The researchers identified chromosomal regions containing genes that affect GGT and ALB variation, which may also influence cardiovascular health.
Researchers have identified and grouped the genes responsible for cell wall development in maize, enabling better study of biomass production. The discovery expands their ability to discover ways to produce biomass suitable for biofuels production.
Researchers at UAB have discovered the genetic identity of a cellular receptor for the immune system's first-response antibody, shedding light on infection control and immune disorders. The discovery proposes renaming the gene linked to this receptor to better describe its role in early immune responses.
Researchers at the University of Pittsburgh are using a mouse model to identify genes that cause congenital heart defects, which affect up to 1% of live births. The goal is to develop a diagnostic chip that can rapidly identify genetic root causes of specific heart defects.
Researchers found a population of tropical butterflies exhibiting diverging color patterns and reproductive preferences, suggesting the potential emergence of two distinct species. The study provides insights into the earliest stage of ecological speciation, where natural selection drives the divergence of populations into new species.
A new genetic method allows for precise identification of all eight tuna species from processed tissue, helping conservation efforts and trade controls. The analysis of DNA sequence variability enables full discrimination between the recognized species.
A recent study published in BMC Biology identified genetic pathways associated with moderate alcohol consumption, but found no correlation between these genes and alcohol dependence. The research team found that drinking behavior was linked to pleasure and reward pathways in the brain, similar to satiety and appetite for food.
A Virginia Commonwealth University study identified a key gene regulating ovarian follicle development in mice, which may help understand human fertility issues. Female mice lacking the Smad-3 gene showed reduced ability to respond to FSH stimulation, leading to infertility.
Researchers have identified the 'master gene' E4bp4, which drives blood stem cells to produce disease-fighting Natural Killer immune cells. The discovery could lead to new ways to treat cancer and autoimmune diseases by boosting the body's production of these frontline tumour-killing cells.
Researchers at the University of Virginia have identified a gene in cowpea that confers resistance to Striga, a parasitic flowering plant that attacks the roots of host plants. The discovery is significant as it could help develop strategies for improving resistance to Striga in other affected crops.
Researchers at UBC found a mutant gene in freshwater sticklebacks that drives their tendency to relocate instead of adapting to new environments. This 'wanderlust gene' is associated with the loss of bony lateral plates and affects salinity tolerance.
A TGen-led research team has been awarded a $1 million grant by the Melanoma Research Alliance to identify novel melanoma risk genes. The team, led by Dr. Jeffrey Trent, aims to characterize genes influencing melanoma risk and develop targeted screening or prevention efforts.
Researchers have developed a yeast model to identify genes that contribute to cancer growth. The study found that point mutations in just a few genetic loci are responsible for the faster growth of cells, rather than aneuploidy. This discovery could help guide the search for new cancer genes in humans.
Researchers identified the hSDH5 gene as mutated in a hereditary form of paraganglioma, a rare neuroendocrine tumor. The study found that individuals with the mutation are at risk for developing tumors, and genetic testing can help identify those at risk.
A new gene, RCP, has been identified as a potential breast cancer-promoting gene, with overexpression causing tumor cell characteristics and metastasis. Targeting RCP may provide a way to inhibit the known tumor-promoting pathway through activation of the RAS signaling pathway.
A recent study published in JAMA Network has found a network of altered genes that appear to play a crucial role in the development and progression of brain tumors. The researchers identified seven landscape genes that are associated with patient prognosis and survival.
A network of 31 mutated genes has been identified as the driving force behind glioblastoma growth. Annexin A7, a vital guard gene, is lost in most cases, allowing tumors to flourish. The discovery offers new therapeutic targets and potentially extends patient survival.
Researchers have identified 20 genes involved in cholesterol regulation, including 12 previously unknown genes. This discovery may lead to new treatments for cholesterol-related diseases and help fight heart disease.
Researchers identified backup genes with similar sequences that can replace failed master genes, explaining experimental results and highlighting the robustness of cells as computational devices. The study found that removing a master gene and its immediate backup has little effect, but removing both has significant consequences.
A study published in BMC Biology has identified 59 genetic mutations in 57 genes that impact the behavior of fruit flies. Researchers found that certain mutations increase aggression, while others make the flies more placid.
Researchers at Northwell Health have identified a new risk factor gene, REL, associated with rheumatoid arthritis. The study found that this gene is common in people in North America and may confer an important survival advantage.
Researchers have developed a method to quickly identify shRNA that turns genes on and off, enabling complex genetic screens at minimal cost. The tool has the potential to revolutionize the study of gene function in mammals, paving the way for targeted therapeutics.
Two genes have been identified as key regulators of female sexual maturation, with their variants associated with earlier onset of menstruation. The study's findings suggest a genetic basis for the links between early menstruation and body mass index and height.
Researchers have identified a potential genetic link to vesicoureteric reflux (VUR), a common cause of urinary tract infections and kidney failure in children. The study found that the VUR susceptibility gene is located on chromosome 12 and may be inherited in an autosomal recessive fashion.
The SLC25A38 gene is responsible for congenital sideroblastic anemia, a rare disease characterized by ringed sideroblasts in bone marrow. Researchers identified the causal mutation in zebra fish, showing its role in hemoglobin synthesis.
A team of scientists from Canada, Spain and the US identified a key gene that allows plants to defend against environmental stresses like drought, freezing and heat. They discovered a receptor that activates abscisic acid (ABA), a hormone helping plants survive drought.
Researchers at the University of Liverpool have developed a new method to identify genes that help protect the body from age-related changes. The study analyzed over five million gene measurements across multiple tissue types in animals and humans, highlighting key biological mechanisms that allow the body to adapt to aging.
Scientists at the University of Cincinnati have identified the RGS17 gene as a major suspect in familial lung cancers. Further investigation may lead to genetic testing for high-risk patients, enabling early detection and treatment.
Researchers at Ben-Gurion University have identified two genes that increase plant tolerance to heat, salt, and drought. The collaboration will help identify additional candidate genes for developing stress-resistant crops.
Researchers at UCLA have identified a gene mutation responsible for short-rib polydactyly syndrome, a deadly disorder that kills newborn babies. The discovery will allow for earlier testing of embryos at risk for the disease, potentially saving lives and reducing the emotional burden on families.
Researchers identified 14 gene variants associated with prolonged QT interval, a known risk factor for sudden cardiac death. Individuals with the top genotype scores were found to have a higher risk of prolonged QT intervals and increased mortality.
Researchers have identified 10 genes linked to changes in QT interval duration, a key factor in sudden cardiac death. The discovery could help identify individuals at risk and aid pharmaceutical companies in developing safer drugs.
Two University of Alberta researchers have discovered eight genes directly related to disc degeneration, providing valuable insights into its biological mechanisms. The study's findings may lead to effective interventions for individuals prone to spine problems, such as those with obesity or genetic susceptibility.
A new gene mutation has been identified as a common cause of inherited ALS, affecting motor neurons in the central nervous system. This discovery is part of a national study led by Northwestern University, aiming to understand the triggers of motor neuron death and develop new treatments.
Researchers at the University of Montreal have identified gene mutations in the SYNGAP1 gene that affect learning and memory in children with non-syndromic mental deficiency. The study found that three percent of affected children had new deleterious mutations, leading to delays in language and mental development.
Researchers at Liverpool School of Tropical Medicine have identified two genes associated with resistance to pyrethroid insecticides in Anopheles funestus and Anopheles gambiae mosquitoes. This discovery provides early warning for future control problems due to insecticide resistance.
Researchers identified a DNA region controlling HGF gene activity and found shortened regions in most breast cancer patients, who were younger than those with normal lengths. This discovery suggests a potential marker for increased breast cancer risk and may be linked to other cancers overexpressing HGF.
Scientists at the University of Utah identified a worm gene crucial for damaged nerve cells to regenerate and showed that over-activating it can speed up nerve regeneration. The study's findings offer hope for new treatments for nerves injured by trauma or disease.
Researchers at U-M Comprehensive Cancer Center identified recurrent gene fusions that drive certain cancers to develop. New gene sequencing technology enabled quicker and easier detection of these fusions.
Researchers at Duke University Medical Center have found a genetic variation in the neuropeptide Y gene that increases susceptibility to early coronary artery disease. The study found six related variations in the gene associated with transmission from generation to generation and association across a population of patients.
Researchers identified genes that code for proteins controlling gene reading, revealing 'gene grammarians' linked to DNA structure. This discovery provides new insights into epigenetic control and environmental effects on the human genome.
Researchers have identified a set of genes responsible for producing the deadly toxin botrydial in gray mold, and found that shutting off this gene can stop toxin production. The discovery offers hope for finding natural ways to eliminate gray mold without using expensive fungicides.
A team of researchers led by University of Georgia's Wayne Parrott is using a jumping gene in rice and radiation to identify key genes in soybeans that can be used to produce a better bean. This project aims to improve soybean yield, disease resistance and nutritional content.
Purdue University researchers are working on a new technique called MAGIC to identify gene combinations that increase disease resistance and stress tolerance in crops. By analyzing the genetic diversity of maize, they aim to engineer plants that can withstand most diseases and improve crop yields.
Researchers aim to identify undiscovered genes involved in early breast cancer stages by studying genetic information from thousands of breast samples. The technique could help monitor women at higher risk due to inherited gene defects, reducing mortality from breast cancer.