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Breakthrough technology offers promising treatment for ischemic retinopathy

Researchers develop technology that alleviates retinal pathologies by targeting mitochondrial chaperone TRAP1, which is implicated in the breakdown of blood-retinal barrier and pathological neovascularization. This treatment approach holds great promise for revolutionizing the treatment landscape for ischemic retinopathy.

SourceUlsan National Institute of Science and Technology(UNIST)·JournalAdvanced Science·DateJan 24, 2024
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Nutrients drive cellular reprogramming in the intestine

Researchers found that enteroendocrine cells in Drosophila intestinal epithelium undergo dedifferentiation into intestinal stem cells in response to nutritional changes, such as recovery from starvation. This process is vital for ISC expansion and subsequent intestinal growth following food intake.

SourceTohoku University·JournalDevelopmental Cell·DateSep 11, 2023