Research on how genomes change over time. Covers hidden DNA structure, chromosome bursts in cancer, plant pangenomes, and microbial adaptation.
A new study provides comprehensive genomic resources for pangolins, helping protect these threatened mammals from extinction due to habitat loss and trafficking. The data will aid in conservation priorities and management plans, as well as tracing the pangolin trade.
A new study has found that bats' extraordinary ability to host and survive infections may be linked to their low cancer rates. Researchers sequenced the genomes of two bat species and compared them to other mammals, discovering genetic adaptations that allow bats to tolerate viral infections.
Researchers use genomic surveillance to identify distinct sexual networks for syphilis transmission in England, highlighting the presence of drug resistance. The study reveals information beyond standard epidemiological surveillance data, aiding public health strategies to break transmission chains.
The study reveals extensive genome size variation among closely related algal strains, with a more than twofold range of approximately 450-1,100 megabases. Genome-wide copy number variation, rather than duplication or proliferation, drives this dynamics, suggesting rapid changes in genome size through frequent duplications and deletions.
A KAUST-led team has compiled the first complete genome map of einkorn, an ancient grain that could help develop bread wheat varieties with enhanced disease resistance and improved hardiness. The study reveals a complex evolutionary history of wheat species, including gene flow between einkorn and wild cousins.
A new study provides new insights into the genomic architecture and evolutionary mechanisms that have allowed clownfish to diversify and thrive in various ecological niches. The study revealed a genome-wide acceleration in evolution among clownfish, with over 5% of all genes found to be under positive selection.
Researchers have identified 30 basic units of 'synteny' that exist in all butterflies and moths, dating back to their common ancestor with caddisflies. This study improves understanding of chromosome evolution in Lepidoptera and may provide insights into other animal or plant groups.
Researchers found that the annulated sea snake possesses four intact copies of the opsin gene SWS1, two with ancestral ultraviolet sensitivity and two with evolved sensitivity to longer wavelengths. This suggests that sea snakes have regained color discrimination to distinguish predators, prey, and mates in their marine habitats.
Researchers from IMBA identify a family of virus-like transposons called Mavericks that facilitate horizontal gene transfer (HGT) between reproductively isolated worm species. The study reveals the role of Mavericks in overcoming the species barrier, with potential applications in pathogen control and genomic innovation.
A study published in Science Advances discovered that talitrids, a group of small crustaceans, independently colonized mountain habitats four times during the Oligocene and Miocene periods. Genetic adaptations allowed them to survive in colder environments and establish themselves in diverse habitats worldwide.
Researchers, led by Elizabeth King, aim to develop a knowledge base on complex genetic traits using fruit fly models. The project seeks to address the scientific knowledge gap in this field by focusing on interconnectedness among multiple factors.
Researchers have pinpointed a previously hidden whole genome duplication in the common ancestor of sturgeons and paddlefish, which may have provided genetic variations that helped these species survive mass extinctions. The discovery suggests that there may be many more overlooked whole genome duplications in other species before perio...
Scientists developed a new diagnostic test for chytridiomycosis, identifying previously undetected strains and detecting pathogens in amphibians worldwide. The test's success verified its affordability as an alternative for widespread surveillance, addressing the urgent need for rapid detection of the disease.
Researchers use chromosome structure to determine that comb jellies were the first lineage to branch off from the animal tree, followed by sponges. This finding sheds light on how animals arose and evolved into the diverse species we see today.
A USC researcher and international team identified consistent DNA base pairs across 240 mammals, including humans, that play a key role in human disease. These 'constrained' base pairs remained generally consistent over millions of years of evolution and are significantly linked to genetic variation.
The study reveals that mammals diversified before the K-Pg extinction, driven by continental drifting and stability following the mass extinction. This led to the rich diversity of mammal lineages, including carnivores, primates, and hoofed animals.
A large-scale genomic study of 240 mammal species reveals previously uncharacterized regulatory elements in the human genome, linked to disease risks and distinctive traits. The research provides insights into the evolutionary development of mammalian genomes and their potential applications in medical research.
Large structural changes in human ancestors' genomes may have sparked smaller changes that set human brains apart from other primates. Researchers found that many enhancers, which regulate brain development, are located near these regions, suggesting a link between DNA folding and brain evolution.
This study reconstructs Sessilida's phylogenetic tree using infraciliature and silverline system, establishing two new families. It challenges traditional morphology-based classification and provides insights into the origin and evolution of this group.
Researchers have sequenced the genomes of two hornet species, revealing clues to their invasive success. The study found rapid genome evolution and genes related to communication and smell, which may help explain why hornets are successful as invasive species across the globe.
The new CALANGO software helps untangle genetic factors associated with shared characteristics, such as antibacterial resistance and agricultural improvements. It enables scientists to explore vast amounts of genomic data across thousands of organisms.
A recent study reveals the first high-quality nuclear genome sequence and assembly of Babesia duncani, a neglected species until now. The parasite's evolution and mechanism of virulence have been identified, providing leads for the development of effective therapies.
Researchers at University of California - San Diego found that vertebrates acquired a special protein from bacteria more than 500 million years ago. This discovery reveals a new piece of genetic material introduced from foreign bacterial genes, leading to unique functionality in vertebrate eyes.
A team of researchers compared 1,800 de novo proteins from fruit flies and humans with computer-generated proteins, revealing small but significant differences in their stability and solubility. The study suggests that natural selection may play a role in the early emergence of these proteins.
Researchers compared woolly mammoth genomes with modern-day elephants to find unique traits. They identified genes responsible for small ears, fat metabolism, and cold perception, which became more defined over time.
Researchers identify egg yolk proteins retained in viviparous sharks and rays, which may provide nutrition to developing embryos. The study suggests that these proteins have evolved a new function in cartilaginous fishes, potentially facilitating the transition from egg-laying to live birth.
A new study by Institut Pasteur reveals that the 'bony-tongues' and 'eels' are genetically linked, shedding light on the evolutionary history of teleost fishes. The researchers sequenced genomes of several species and reconstructed relationships between different fish groups.
A recent study by the University at Buffalo has discovered that genetic variations affecting immunity and metabolism have been preserved in humans for millions of years. This finding supports the theory of balancing selection, which suggests that certain genetic traits can be beneficial or harmful depending on environmental conditions.
Researchers have created detailed genetic maps of green and leatherback sea turtle genomes, providing insights into their unique adaptations and evolutionary history. The study reveals that genetic differences between the two species are mainly found on microchromosomes, which may hold the key to each species' survival.
Scientists sequenced genomes of 'eel' species to reconstruct relationships between teleost fishes, ending decades-long controversy over their evolutionary history. The analysis revealed a single group, Eloposteoglossocephala, that encompasses both eels and bony-tongues.
An international team of researchers has created a detailed genetic map of two sea turtle species, revealing surprising similarities and differences. The study finds that green turtles have evolved more immune-related genes, while leatherbacks have historically lower population levels and reduced genetic diversity.
Researchers at University of Oklahoma sequenced the genomes of decades-old Daphnia resting eggs from a polluted lake, revealing natural selection signs and genetic changes underlying rapid evolution. This study provides molecular evidence for adaptation to salinization in a keystone aquatic species.
A transnational collaboration led to the characterization of Physostegia chlorotic mottle virus (PhCMoV), a plant disease first identified in Austria in 2018. The study revealed that PhCMoV can infect at least nine plant species, causing severe fruit symptoms on economically important crops.
A study published in Evolution found that polygamous birds have higher efficiency of natural selection, leading to fewer harmful mutations and increased genetic diversity in small subsets of species with polygamous females.
Scientists have mapped and analyzed DNA methylation profiles in 580 different animal species, providing insights into the evolutionary conservation of epigenetic mechanisms. The study reveals that DNA methylation constitutes a cancer-protective mechanism in large animals with long lifespans, contradicting Peto's paradox.
Researchers analyzed the genomes of over 2,800 individuals in Europe to study the evolution of immune system genes. They found that mutations advantageous for defending against pathogens increased in frequency after the Bronze Age, while those increasing disease risk fell.
Scientists have developed a novel metric to analyze the rate of convergent evolution in protein-coding DNA sequences. This approach can reveal which genetic changes are associated with phenotypic traits, shedding light on how species diversify over time.
A fungus infecting salamanders has evolved to contain multiple copies of jumping genes, which contribute to its increased virulence. The 'copy and paste' mechanism allows the fungus to amplify skin-destruction genes, making it more deadly.
Researchers sequenced the genomes of two endangered sharks, finding low genetic diversity and signs of inbreeding in great hammerheads. In contrast, shortfin makos showed higher genetic diversity and limited inbreeding, offering a glimmer of hope for conservation efforts.
A study by Universitat Autònoma de Barcelona reveals the three-dimensional structure of mammalian genomes is more diverse than previously seen, with different patterns of chromosome folding identified in various species. The research provides new interpretative hypotheses about the plasticity of the genome and its role in evolution.
A team of scientists identified 155 new genes that spontaneously arose from tiny sections of the human DNA, some associated with growth defects, muscular dystrophy, and other diseases. These 'microgenes' also play a role in maintaining healthy heart tissue.
A new study led by UCSC scientists suggests that introners are the source of most introns across species, providing a plausible explanation for their vast majority. The researchers found evidence of introners in 5.2% of surveyed eukaryotic species and suggest they may be a fundamental mechanism driving genomic complexity.
Researchers at Hokkaido University discovered a novel sex-determination mechanism in the Amami spiny rat, a species lacking the Y chromosome and Sry gene. The mechanism involves the upregulation of Sox9 gene on chromosome 3, induced by a new regulatory element similar to Enh14.
Researchers have uncovered a common ancestor among 600 disparate fungi, revealing a long-forgotten branch in the fungal family tree. The discovery sheds light on the evolutionary history of these unusual organisms and their unique characteristics.
Researchers have discovered a family of selfish genes, wtf, that have survived for over 100 million years in yeast, contradicting established beliefs on their longevity. These 'killer meiotic drivers' transmit themselves to half of offspring and destroy reproductive cells without being suppressed by natural selection.
Researchers found that horizontal gene transfer can accelerate bacterial adaptation under most growth conditions, but not all. By analyzing the fitness effects of gene transfer, they can predict when it will provide an advantage.
Researchers reconstructed the genome organization of the earliest common ancestor of all mammals using high-quality genome sequences from 32 living species. The study reveals that the mammal ancestor had 19 autosomal chromosomes and conserved gene blocks across modern mammalian genomes.
Researchers have reconstructed the genome of the common ancestor of all mammals, revealing key features such as 19 autosomal chromosomes and 38 sex chromosomes. The study provides insights into the evolutionary stability of gene order and orientation on chromosomes over millions of years.
Researchers have identified four genes in corn and Arabidopsis that regulate root growth in response to gravity, a trait essential for drought tolerance and efficient water use. The study's approach, leveraging genomic comparisons between distantly related species, has the potential to be applied to other traits.
A new study finds that lab adaptation involves mutations to highly conserved proteins, but natural adaptation exhibits more complex patterns, including non-conservation within functional domains. Lab conditions differ significantly from natural environments with variable and changing selective pressures.
A study in the Netherlands found that restricting flights from countries where COVID-19 variants of concern emerge is not enough to halt their spread. The researchers analyzed nearly 40,000 genome sequences and found that all four VOCs had already been introduced into the country by the time flight restrictions were implemented.
A new study from Harvard University identifies the genes and genetic sequences that orchestrate the formation of the human pelvis during pregnancy. The research shows that key pelvic features form around 6- to 8-week mark, including a curved and basin-like shape.
Threespine stickleback fish evolved resistance to freshwater tapeworms by forming scar tissue around them, which prevents the worms from growing. However, this defense has a significant fitness cost for female sticklebacks, as they are 80% less likely to successfully breed due to the accumulated scarring.
A recent study published in Science Advances reveals a correlation between genomic attributes and life history traits in Neoavian birds. The researchers found that generation time and body mass are associated with the length of orthologous microsatellites, transposable elements, and DNA deletions.
Two papers published in Nature Plants unveil the first full-length genomes for homosporous ferns, a group containing 99% of modern fern diversity. The Ceratopteris genome suggests that ferns stole genes from bacteria for anti-herbivory toxins.
A new study reveals that the emergence of a new gene called PGBD1 is linked to the evolution of a new structure in nerve cells. PGBD1 controls paraspeckles, tiny structures that act like traps for RNAs and proteins, and its regulation is crucial for nerve cell development.
Researchers identified 15 instances of mucinization, where new mucins emerged from non-mucin proteins by adding repeating sequences. This process transformed the proteins into mucins with gooey consistency, contributing to their various biological functions.
Scientists reconstruct evolution of complex multicellular organisms using genomic data and computational models, revealing gradual changes that began early in evolution. The research reveals distinct paths taken by animal and fungal lineages, shedding light on their shared eukaryotic supergroup.
A recent study found that ocean cooling over the past 100 million years led to increased body size in tetraodontiform fishes, adhering to Cope's and Bergmann's rules. The researchers combined genomic and fossil data to support this finding, which was previously less well understood for ectothermic species.
A newly identified species of Liberibacter, a family of bacteria known for causing citrus greening disease, is rapidly evolving its ability to infect insect hosts. The research team found 21 genes associated with infectious qualities and identified mutations affecting pilus proteins that allow the bacteria to move into host insects.