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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

Butterflies and moths share ancient ‘blocks’ of DNA

Researchers have identified 30 basic units of 'synteny' that exist in all butterflies and moths, dating back to their common ancestor with caddisflies. This study improves understanding of chromosome evolution in Lepidoptera and may provide insights into other animal or plant groups.

Sea snakes may have evolved to see colors again

Researchers found that the annulated sea snake possesses four intact copies of the opsin gene SWS1, two with ancestral ultraviolet sensitivity and two with evolved sensitivity to longer wavelengths. This suggests that sea snakes have regained color discrimination to distinguish predators, prey, and mates in their marine habitats.

Virus-like transposons wage war on the species barrier

Researchers from IMBA identify a family of virus-like transposons called Mavericks that facilitate horizontal gene transfer (HGT) between reproductively isolated worm species. The study reveals the role of Mavericks in overcoming the species barrier, with potential applications in pathogen control and genomic innovation.

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From sea to mountain: legend of a terrestrial crustacean

A study published in Science Advances discovered that talitrids, a group of small crustaceans, independently colonized mountain habitats four times during the Oligocene and Miocene periods. Genetic adaptations allowed them to survive in colder environments and establish themselves in diverse habitats worldwide.

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SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

What did the earliest animals look like?

Researchers use chromosome structure to determine that comb jellies were the first lineage to branch off from the animal tree, followed by sponges. This finding sheds light on how animals arose and evolved into the diverse species we see today.

Texas A&M research redefines mammalian tree of life

The study reveals that mammals diversified before the K-Pg extinction, driven by continental drifting and stability following the mass extinction. This led to the rich diversity of mammal lineages, including carnivores, primates, and hoofed animals.

Study suggests catalyst for human brain evolution

Large structural changes in human ancestors' genomes may have sparked smaller changes that set human brains apart from other primates. Researchers found that many enhancers, which regulate brain development, are located near these regions, suggesting a link between DNA folding and brain evolution.

Genomes from 240 mammal species explain human disease risks

A large-scale genomic study of 240 mammal species reveals previously uncharacterized regulatory elements in the human genome, linked to disease risks and distinctive traits. The research provides insights into the evolutionary development of mammalian genomes and their potential applications in medical research.

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From oral structure to molecular evidence: new insights into the evolutionary phylogeny of the ciliate order Sessilida (Protista, Ciliophora), with the establishment of two new families and new contributions to the poorly studied family Vaginicolidae

This study reconstructs Sessilida's phylogenetic tree using infraciliature and silverline system, establishing two new families. It challenges traditional morphology-based classification and provides insights into the origin and evolution of this group.

Newly sequenced hornet genomes could help explain invasion success

Researchers have sequenced the genomes of two hornet species, revealing clues to their invasive success. The study found rapid genome evolution and genes related to communication and smell, which may help explain why hornets are successful as invasive species across the globe.

Researchers warn of tick-borne disease babesiosis

A recent study reveals the first high-quality nuclear genome sequence and assembly of Babesia duncani, a neglected species until now. The parasite's evolution and mechanism of virulence have been identified, providing leads for the development of effective therapies.

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Study compares de novo proteins with randomly produced proteins

A team of researchers compared 1,800 de novo proteins from fruit flies and humans with computer-generated proteins, revealing small but significant differences in their stability and solubility. The study suggests that natural selection may play a role in the early emergence of these proteins.

Who are the first ancestors of present-day fish?

A new study by Institut Pasteur reveals that the 'bony-tongues' and 'eels' are genetically linked, shedding light on the evolutionary history of teleost fishes. The researchers sequenced genomes of several species and reconstructed relationships between different fish groups.

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Who are the first ancestors of present-day fish?

Scientists sequenced genomes of 'eel' species to reconstruct relationships between teleost fishes, ending decades-long controversy over their evolutionary history. The analysis revealed a single group, Eloposteoglossocephala, that encompasses both eels and bony-tongues.

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Polygamous birds have fewer harmful mutations

A study published in Evolution found that polygamous birds have higher efficiency of natural selection, leading to fewer harmful mutations and increased genetic diversity in small subsets of species with polygamous females.

From octopus to elephant: a molecular zoo of epigenetics

Scientists have mapped and analyzed DNA methylation profiles in 580 different animal species, providing insights into the evolutionary conservation of epigenetic mechanisms. The study reveals that DNA methylation constitutes a cancer-protective mechanism in large animals with long lifespans, contradicting Peto's paradox.

How evolution works

Scientists have developed a novel metric to analyze the rate of convergent evolution in protein-coding DNA sequences. This approach can reveal which genetic changes are associated with phenotypic traits, shedding light on how species diversify over time.

AmScope B120C-5M Compound Microscope

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‘Jumping genes’ help fungus kill salamanders

A fungus infecting salamanders has evolved to contain multiple copies of jumping genes, which contribute to its increased virulence. The 'copy and paste' mechanism allows the fungus to amplify skin-destruction genes, making it more deadly.

Humans continue to evolve with the emergence of new genes

A team of scientists identified 155 new genes that spontaneously arose from tiny sections of the human DNA, some associated with growth defects, muscular dystrophy, and other diseases. These 'microgenes' also play a role in maintaining healthy heart tissue.

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Novel sex-determination mechanism revealed in mammals

Researchers at Hokkaido University discovered a novel sex-determination mechanism in the Amami spiny rat, a species lacking the Y chromosome and Sry gene. The mechanism involves the upregulation of Sox9 gene on chromosome 3, induced by a new regulatory element similar to Enh14.

Genome studies uncover a new branch in fungal evolution

Researchers have uncovered a common ancestor among 600 disparate fungi, revealing a long-forgotten branch in the fungal family tree. The discovery sheds light on the evolutionary history of these unusual organisms and their unique characteristics.

Revealing the genome of the common ancestor of all mammals

Researchers reconstructed the genome organization of the earliest common ancestor of all mammals using high-quality genome sequences from 32 living species. The study reveals that the mammal ancestor had 19 autosomal chromosomes and conserved gene blocks across modern mammalian genomes.

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Revealing the genome of the common ancestor of all mammals

Researchers have reconstructed the genome of the common ancestor of all mammals, revealing key features such as 19 autosomal chromosomes and 38 sex chromosomes. The study provides insights into the evolutionary stability of gene order and orientation on chromosomes over millions of years.

What keeps plant roots growing toward gravity? Study identifies four genes

Researchers have identified four genes in corn and Arabidopsis that regulate root growth in response to gravity, a trait essential for drought tolerance and efficient water use. The study's approach, leveraging genomic comparisons between distantly related species, has the potential to be applied to other traits.

Targeted travel restrictions fail to halt spread of COVID-19

A study in the Netherlands found that restricting flights from countries where COVID-19 variants of concern emerge is not enough to halt their spread. The researchers analyzed nearly 40,000 genome sequences and found that all four VOCs had already been introduced into the country by the time flight restrictions were implemented.

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Why do humans walk upright? The secret is in our pelvis

A new study from Harvard University identifies the genes and genetic sequences that orchestrate the formation of the human pelvis during pregnancy. The research shows that key pelvic features form around 6- to 8-week mark, including a curved and basin-like shape.

How new structures evolve

A new study reveals that the emergence of a new gene called PGBD1 is linked to the evolution of a new structure in nerve cells. PGBD1 controls paraspeckles, tiny structures that act like traps for RNAs and proteins, and its regulation is crucial for nerve cell development.

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The evolution of mucus: How did we get all this slime?

Researchers identified 15 instances of mucinization, where new mucins emerged from non-mucin proteins by adding repeating sequences. This process transformed the proteins into mucins with gooey consistency, contributing to their various biological functions.

Study finds that ocean cooling over millennia led to larger fish

A recent study found that ocean cooling over the past 100 million years led to increased body size in tetraodontiform fishes, adhering to Cope's and Bergmann's rules. The researchers combined genomic and fossil data to support this finding, which was previously less well understood for ectothermic species.

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CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Cousin of crop-killing bacteria mutating rapidly

A newly identified species of Liberibacter, a family of bacteria known for causing citrus greening disease, is rapidly evolving its ability to infect insect hosts. The research team found 21 genes associated with infectious qualities and identified mutations affecting pilus proteins that allow the bacteria to move into host insects.

New research on the emergence of the first complex cells challenges orthodoxy

A new study challenges a popular scenario explaining the origin of eukaryotes, suggesting that cells can grow to considerable volume without acquiring mitochondria. Researchers explore energy requirements and genome arrangement in prokaryotes and eukaryotes, revealing overlap between cell types rather than a hard boundary line.

DJI Air 3 (RC-N2)

DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

Tree fern genome provides insights into its evolution

The study of flying spider-monkey tree fern genome provides insights into fern evolution and arborescence. Ferns developed vascular tissues, including xylem and phloem, to transport water, nutrients, and food, which is a key innovation in land plant evolution.

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