Research on how genomes change over time. Covers hidden DNA structure, chromosome bursts in cancer, plant pangenomes, and microbial adaptation.
Researchers found 87 genes affected by deletions or short insertions in the woolly mammoth genome, potentially impacting its adaptability to cold environments. These changes may have contributed to unique traits such as fur growth and hair shape.
A new study challenges a popular scenario explaining the origin of eukaryotes, suggesting that cells can grow to considerable volume without acquiring mitochondria. Researchers explore energy requirements and genome arrangement in prokaryotes and eukaryotes, revealing overlap between cell types rather than a hard boundary line.
Holocentric chromosomes have been found to promote rapid genome evolution by allowing the formation of new species through chromosome fusions. This non-classical mode of chromosome organization also stabilizes chromosomal fragments and facilitates DNA gene swapping, making it an exciting area for plant breeding.
Researchers uncover the 'cortex' gene responsible for leaf mimicry in Kallima butterflies, revealing a complex interplay between genetics and environmental pressures. The study provides insights into the evolution of this remarkable adaptation and its potential applications in understanding biodiversity.
Researchers confirm COVID-19 originated from live animals sold at Huanan Seafood Wholesale Market in Wuhan, China. The market was the epicenter of the epidemic, with vendors getting infected first and setting off a chain of infections.
The study of flying spider-monkey tree fern genome provides insights into fern evolution and arborescence. Ferns developed vascular tissues, including xylem and phloem, to transport water, nutrients, and food, which is a key innovation in land plant evolution.
Researchers found that domesticated rye has smaller recombining regions, making it less resistant to climate change. In contrast, wild rye has a more diverse genetic makeup and can freely recombine its genetic material.
The study reveals that female Prussian carps use hijacked sperm to reproduce, producing only female clones. This unique reproductive method has allowed the species to colonize new habitats and outcompete native species.
A new study suggests that a unique gene variant supporting cognitive health in older humans may have first emerged to protect against infectious pathogens like gonorrhea. This variant, linked to CD33, allows brain immune cells to break down damaged brain cells and amyloid plaques associated with Alzheimer's disease.
New research reveals that rattlesnakes maintain a broad and diverse toolkit of genes encoding snake venom, allowing them to adapt as local prey and conditions change. This adaptation enables snakes to overcome prey species evolving resistance to their venoms over millions of years.
A study reveals that over 1,400 genes in 218 insect species originated from bacteria, viruses, fungi, and plants through horizontal gene transfer. This discovery suggests that these genes contributed to beneficial traits such as mating behavior, nutrition, and adaptation to environmental changes.
Scientists have identified 118 toxin genes in the many-banded krait's genome, including a diverse three-finger toxin family. The study provides valuable resources for developing next-generation antivenoms with well-defined compositions.
Genomic data reveals two distinct species of scrub jays: A. sumichrasti, endemic to southern Mexico, and A. texana, found only in Texas. The study's findings support the recognition of these new species based on phenotypic, behavioral, and genetic differences.
Researchers have identified over 1,500 genetic differences between migratory and non-migratory hoverflies, shedding light on the genetic pathways involved in migration. The study reveals suites of genes being activated in concert, including insulin signalling for longevity and pathways for immunity.
Researchers have discovered a selfish genetic element, known as Segregation Distorter (SD), that skews genetic inheritance. SD has caused dramatic changes in chromosome organization and genetic diversity, leading to the accumulation of deleterious mutations.
Researchers found that different lineages of Cryptosporidium parvum are increasingly exchanging their DNA, which helps the parasite evolve faster and potentially result in more virulent strains. The study suggests that globalization and close contact with animals increase the rate of genetic exchange.
Researchers at NC State University discovered that a maize gene called HPC1 helps plants adapt to high altitudes and cold temperatures. The gene originated from teosinte mexicana and has been retained in modern-day corn, allowing it to thrive in challenging environments.
A new study explores the characteristics of 36 basic variants of the Holliday junction, a fundamental building block used in DNA nanoforms. The results show that sequences forming the four protruding arms of the junction can enhance or hinder crystallization processes.
A recent study has identified an important molecular analogy between the octopus brain and the human brain, specifically with LINE transposons active in both species. This discovery sheds light on the secret of the intelligence of these fascinating organisms, suggesting a convergent evolution of cognitive abilities.
A new analysis of ancient and contemporary genomes shows that more than half of historical groups experienced founder events, leading to reduced genetic diversity. This research has significant implications for scientists studying human genetic variation and the discovery of disease-causing mutations.
The study reveals that the 16th-century E. coli acquired novel genes and antibiotic resistance over time, posing a significant threat to human health despite not causing pandemics. The reconstructed genome provides valuable insights into its evolution and potential role as an opportunistic pathogen.
Researchers at Cornell University named a new green alga species after poet Amanda Gorman, who inspired them during a challenging year. The discovery was made by accident while studying hornwort plants and contains unique DNA from fungi and bacteria.
A recent study by Indiana University researchers found that the structure of DNA storage in archaea affects its evolution rate. The study discovered that compacted DNA compartments change at a faster rate than less compacted ones. This discovery has potential impacts on research on genetic diseases like cancer.
Researchers at the Center for Genomic Regulation (CRG) found that chromatin, a genetic architecture that protects DNA and regulates gene expression, originated in ancient microbes between 1-2 billion years ago. This eukaryotic innovation has been essential for life since its emergence.
A group of researchers discovered a new species of green algae, Gormaniella terricola, in Central New York State. The alga's unique chloroplast genome was found to contain DNA from fungi and bacteria, highlighting the importance of horizontal transfer.
Researchers at UTA and international collaborators have discovered the regulatory architecture that drives snake venom expression, shedding light on the evolution of complex traits. The study provides a detailed explanation of how snakes developed specialized venom glands to produce diverse deadly proteins.
A new study finds that polar bears and brown bears have a complicated evolutionary history due to interbreeding. The analysis of modern bear genomes and ancient DNA from a 115,000-year-old tooth reveals gene flow from brown bears into polar bears, challenging previous hypotheses.
A new study examines mathematical models designed to draw inferences about how evolution operates at the level of populations of organisms. The researchers conclude that such models must be constructed with care, avoiding unwarranted initial assumptions and weighing existing knowledge.
Researchers analyzed the repetitive fraction in olive plant genomes, revealing key differences between closely related and distant species. The study sheds light on the evolution of the olive genus and highlights the role of the genome's repetitive fraction in understanding its origins.
The study creates a catalogue of genomic diversity for endangered chimpanzees, allowing researchers to pinpoint the origin of confiscated animals within 100 kilometers. This information can support conservation efforts and combat the illegal trade of chimpanzees.
Researchers find that cooperative breeding in animal societies increases survival chances of carers, leading to higher reproductive success. The study also reveals the relative importance of kin selection and individual selection varies depending on environmental conditions.
Biologists at the University of Pennsylvania have discovered a two-sided genomic arms race between satellite DNA and its binding proteins in fruit flies. The study reveals that when these elements interact, significant costs to fitness can occur, including impacts on fertility and cancer development.
Researchers discovered that ancient retroviruses embedded in human genome can undergo retrotransposition into iPS cells, potentially posing a risk for regenerative medicine. The study found that HERV-K is expressed in SOX2-expressing cells and may cause cancer and neurological diseases by altering gene expression profiles.
A study discovered that snakes and lizards have lost a major type of T cell, γδ T cells, which has raised questions about their immune system. The loss is believed to be an evolutionary adaptation, prompting research into how these animals compensate for the missing T cells.
A study comparing whole genomes of several mustelids, including the tayra and wolverine, identifies multiple sources of genomic variation contributing to species-specific traits. The research sheds light on how these adaptations evolved in response to different ecological challenges.
A new study analyzed genomic data from global populations to identify genetic variants linked to COVID-19 severity. The investigation found dozens of genomic variations in critical genes, suggesting these may have evolved to protect against viruses similar to SARS-CoV-2.
A new study has discovered that rare pieces of genetic code can serve as another layer of control in the genome, essential for fertility and evolutionary innovation. Researchers found that certain tissues are more tolerant of diverse codons, particularly the testes, which may play a critical role in fertility.
A new study reveals that most mutations in biologically essential genes change steadily and randomly across 700 million years of evolution. This constant drift makes it impossible to reliably predict the effects of most mutations into the future or back into the past.
Researchers found that jellyfish's stinging cells evolved by repurposing a neuron inherited from a pre-cnidarian ancestor. This discovery provides insights into the emergence of new cell types and the evolution of biodiversity, suggesting that co-option of ancestral cell types was an important source for new cell functions.
The first farmers emerged from a population admixed between hunter-gatherers from Europe and the Near East, with a mixing process starting around 14,000 years ago. Genetic data from prehistoric skeletons were analyzed using novel demographic modeling techniques to reveal complex population dynamics.
A University of Alberta research team has rewritten the biology of lichen, a textbook case of symbiosis. The study found that lichens do not use sugars produced by algae for growth, but instead store them to preserve cellular content when dry.
A study by UAB and University of Kent researchers found that the 3D structure of male germ cells plays a key role in determining genome evolution. Genome rearrangements were associated with DNA damage locations in spermatids, suggesting that males have a unique impact on genome evolution.
Researchers identified a region of the mouse genome associated with higher mutation rates, which is linked to a specific gene called Mutyh. This finding supports the theory that genetic differences can affect mutation rates, and may also shed light on cancer susceptibility.
Researchers at King Abdullah University of Science & Technology (KAUST) have identified a stem rust resistance gene in Aegilops sharonensis and transferred it to common wheat. The new transgenic wheat lines show high levels of resistance to the stem rust pathogen, providing hope for mitigating the devastating effects of climate change.
Researchers studied the genomes of squid, octopus, and cuttlefish to understand how they developed complex behaviors and organs. The studies found that cephalopod genomes are highly rearranged, with novel gene families that contribute to their unique traits, such as large brains and camouflage capabilities.
A large-scale international study, led by Tel Aviv University's Dr. Omri Bronstein, found that many species of echinoids, including sea urchins, survived a mass extinction event 50 million years earlier than thought. The findings suggest that estimates of evolutionary timelines may err by tens of millions of years.
A study by Kyoto University reveals that crickets' wings form from the lateral tergum of their wingless ancestors. The researchers used gene knockouts and microsurgery to identify key cell types involved in wing formation.
A study found that small genetic variations impact an organism's ability to utilize energy from various nutrients. Researchers identified several genes contributing to sugar tolerance in fruit flies, which are also present in humans and linked to obesity and type 2 diabetes.
Researchers developed a computational technique to predict favorable gene sequences that make Rubisco, a key plant enzyme for photosynthesis. The study found promise for developing faster and more efficient Rubisco enzymes to increase crop yields and adapt to hot, dry future conditions.
A novel approach to understanding sponge evolution reveals two distinct microbiome compositions that led to different feeding strategies and predator protection. The discovery provides insights into the Earth's past and could reveal aspects of ancient ocean chemistry.
Researchers at La Jolla Institute for Immunology discovered a Zika virus mutation that boosts its ability to replicate and infect humans. This mutation allows the virus to evade protective immunity from previous dengue exposure, increasing its transmission potential.
A recent study published in Genome Biology and Evolution found that ancient human remains from Bulgaria are more closely related to contemporary East Asians than Europeans. The researchers propose a scenario where an African population hub expanded into Europe and East Asia around 45,000 years ago, with the European representatives dec...
The study found that cryptochromes are conserved across various green organisms, influencing cell structures responsible for photosynthesis. The researchers discovered that a specific cryptochrome can actually lead to increased growth despite appearing darker green due to denser packed cell membranes.
Researchers discover medusavirus undergoes four stages of maturation within host cells, with unique particle structures and DNA-protein exchange mechanisms. The findings provide new insights into giant viruses' biology and behavior.
The completed human genome assembly has revealed new insights into human evolution and diseases. Researchers found that highly repetitive regions, including segmental duplications, contain genes critical for brain development and function. These findings shed light on the genetic factors that make humans distinct from other primates.
Researchers found that gene duplications can complicate crop improvements, with some plants showing little effect despite similar mutations. This study highlights the need to understand evolutionary changes in plant genomes to develop more predictable crop improvements.
Researchers found no evidence that gelada monkeys' hemoglobin provides increased oxygen-carrying capacity, but discovered other physiological adaptations that enable them to thrive at high altitudes. The study sheds light on the mechanisms behind human adaptation and potential treatments for diseases associated with high altitude.
Researchers found that urbanization increases hydrogen cyanide production in white clover as a defense mechanism against herbivores. The study, published in Science, reveals adaptive evolution due to urbanization is driving global-scale changes in plant species.
The American Association for Cancer Research (AACR) announced its newly elected class of Fellows of the AACR Academy, recognizing distinguished scientists who have propelled innovation and progress against cancer. The 2022 class consists of 33 luminaries from various scientific disciplines.
A genome-scale analysis of echinoids reveals modern species emerged 300 million years ago, survived mass extinction, and diversified rapidly. The findings also suggest sand dollars and sea biscuits originated earlier than thought, with possible fossil record gaps.