Research on how genomes change over time. Covers hidden DNA structure, chromosome bursts in cancer, plant pangenomes, and microbial adaptation.
Researchers have identified a shortened version of the human growth hormone receptor gene, GHRd3, which may help people survive in situations where resources are scarce or unpredictable. The study found that this variant emerged around 1-2 million years ago and was more prevalent in ancient humans and Neanderthals.
A medieval Spanish individual, known as the 'Segorbe Giant,' has been analyzed using ancient DNA. The research found that he had a mix of North African and local Spanish ancestry, suggesting a complex history of migration and intermixing. This study sheds light on a dark event in medieval Spain's past.
Scientists prove Meselson effect in ancient asexual species, showing survival without sexual reproduction is possible. The study of beetle mite Oppiella nova reveals genetic variance and adaptation through independent genome evolution.
Researchers sequenced the genomes of an ancient date palm leaf and found evidence of hybridization with wild relatives. The study sheds light on the evolution of date palms in North Africa, showing that genetic material from another species was present 2,200 years ago.
Researchers tracked insect evolution with major Pacific Ocean currents, revealing species adapted to different conditions. Genetic analysis of ocean skaters found distinct variations among species, mirroring changes in currents and climate.
Research reveals cichlids exhibit highly dynamic sex chromosomes, transitioning between XY and ZW systems. Genome analysis identified over 70 species with distinct sex-determining genes.
A Spartan-led team has assembled the most complete picture of the bowfin genome to date, revealing striking similarities between bowfin gas bladder development and human lung development. This breakthrough provides a better model for studying human health and disease, with potential implications for understanding evolutionary history.
Researchers at McGill University have developed a new way to track genetically modified animals using artificial transgenes. The discovery provides a powerful tool for locating and managing escaped or released GM animals.
Researchers discover that gastrin-releasing peptide (GRP) is widely conserved among vertebrates, but the NMB/bombesin system has diversified in some lineages. GRP has evolved independently from a single ancestral homologue and plays a role in regulating energy intake and expenditure in both amphibians and mammals.
An international team found the genetic basis for the seadragon's lack of teeth, leaf-like appendages and sex-determination gene. The research also showed that males care for fertilized eggs until they hatch.
Researchers completed the first genetic sequencing of a Brazilian snake's genome, revealing that most toxin genes likely arose from existing functions in ancestral species. The study identified markers for comparing toxin genes with non-toxic 'ancestral' genes, shedding light on the evolution of venom production.
A recent study found that most structural variants in cacao genomes are deleterious, impairing gene function and adapting plants to stressors. However, some variants facilitate adaptation by influencing gene expression, particularly those associated with pathogen resistance genes.
A new study reconciles the molecular clock with the fossil record of plants by linking older spore-like microfossils to younger plant spores derived from charophyte algae, revealing the evolutionary assembly of the plant regulatory and developmental genome.
A new study generated 137 whole-genome sequences from eight Middle Eastern populations, filling a major gap in international genomic projects. The researchers found 4.8 million previously undiscovered genetic variants, which could hold medical relevance.
A new study published in Genome Biology found that the ability of gut bacteria to produce spores is associated with their adaptation to humans. Bacteria that can produce spores have larger genomes and are less abundant in the gut, while those that cannot have smaller genomes and are more adapted to human hosts.
A study on gymnosperm diversification reveals that gene duplications are linked to major pulses of phenotypic evolution. The researchers found that ecological opportunity and environmental heterogeneity drove a resurgence of gymnosperm diversification since the rise of angiosperms.
A new study reveals genome duplication events in ancient gymnosperms led to the origin of pines and other conifers, enabling them to adapt to changing ecosystems. The research suggests that duplicated DNA gave rise to unique traits such as diverse cone structures and egglike roots.
A new study in Genome Biology and Evolution reveals extensive gene flow among butterfly lineages, resulting in a network of related species rather than a simple tree. This challenges traditional models of evolution and highlights the importance of adaptive introgression in shaping species diversity.
A waterflea population has undergone rapid evolution in response to predator pressure over nearly two decades, with changes linked to specific environmental conditions. The study highlights the crucial role of standing genetic diversity in supporting adaptive evolution and its implications for conservation biology.
An international team has developed a method to analyze ancient DNA in museum specimens, allowing for their placement on the evolutionary timeline. The technique enabled researchers to trace the evolutionary history of several species over tens of millions of years.
Researchers discovered a novel neurological disorder caused by spontaneous mutations in the RNF2 gene, leading to symptoms such as intellectual disabilities, seizures, and feeding difficulties. The study, led by Dr. Shinya Yamamoto and Dr. Vandana Shashi, found that loss-of-function variants in RNF2 disrupt normal neuronal development ...
Researchers mapped protein domain evolution over 3.8 billion years, revealing a 'big bang' of domain combinations 1.5 billion years ago. This discovery could help understand and engineer proteins for disease management, vaccine design, and preventing pandemics.
Research finds that unusual DNA structures, called G-quadruplexes (G4s), are preserved by natural selection and play a role in gene expression and cellular processes. G4s are more common and stable in regions with important functions, suggesting they should be considered functional elements of the genome.
Researchers used genetic techniques to show that bobtail and bottletail squids share a recent common ancestor, with major biogeographic events influencing their evolution. The study found that these events led to the diversification of many species, with some lineages emerging in response to changes such as the closure of the Tethys Sea.
A team of researchers used phylogenetics to investigate recurrent adaptations in bird mitochondria, finding that most convergence events can be explained by random coincidences rather than adaptation. The study confirms the scientific opinion that distant species choose different ways of similar trait evolution, but challenges the idea...
A new study of Chinese cats reveals the evolutionary uniqueness and premier conservation importance of the elusive Chinese mountain cat, found only in the Tibetan plateau of China. The research resolves taxonomic classification uncertainty and pinpoints the prospects for survival of this endangered species.
Researchers analyzed epigenomic signals in human and primate cell lines, revealing weak signals linked to brain functions. The findings provide insights into the evolution of human biology and offer a new model for studying regulatory elements.
A study published in eLife reveals how plants produce defence chemicals that vary across Europe due to genetic variation, environmental pressures, and geographical location. The research found that different regions have unique profiles of these chemical compounds, shaped by factors such as weather conditions and landscape features.
A study by Columbia University researchers found that eusocial snapping shrimp have larger genomes due to an accumulation of 'jumping' genes called transposable elements. This discovery has significant implications for understanding the relationship between genome evolution and social behavior in various species, including humans.
A study found that social behavior in snapping shrimps influences genome size, with eusocial species having larger genomes and more transposable elements. Genome size varies widely between species and is generally unrelated to complexity.
A recent review in Genome Biology and Evolution discusses the evolutionary fates of supergenes, revealing new findings that challenge classical models. The genomic architecture of a supergene is inextricably tied to its evolutionary fate, with empirical studies yielding surprises about their origin and genetic architecture.
The researchers reported a reference sequence for the supernumerary B chromosome in maize, with key properties such as its origin and molecular mechanism remaining unclear. The study found that the current gene content is a result of continuous transfer from the A chromosomal complement over an extended evolutionary period.
A comprehensive genetic resource of rat-infecting malaria parasites has been published, providing insights into the evolution, virulence, and transmissibility of the disease. The study reveals diverse genetic and phenotypic variations between subspecies, which may aid in understanding malaria parasite gene functions.
Scientists have developed a new framework for describing gene content and order across Brassica species, which will aid in evolution studies. This framework enables the acceleration of beneficial gene exchange between species, ultimately leading to more climate-resilient crops.
Researchers found that Tasmanian devils' genome has undergone widespread evolution in response to transmissible cancer, but distinct sets of genes are involved at different timescales. The study suggests that conservation efforts should focus on maintaining genetic diversity across a wide set of functionally important genes.
Researchers at San Francisco State University have discovered a strange and confounding system of genes in the creeping vole, a tiny rodent native to the Pacific Northwest. The team found that the X and Y chromosomes had fused, causing the X chromosome in males to act like a Y chromosome.
A study found that drastic changes in the Mediterranean climate and geology 6 million years ago led to the emergence of new species in wall lizards. The researchers believe hybridization played a key role in this process, fueling evolution and promoting biodiversity.
A team of scientists from China has sequenced the genome of Lavandula angustifolia to understand the genetics behind its distinctive fragrance. The study revealed that gene duplications and terpenoid diversification led to the evolution of unique compounds, with potential applications in stress relief, skin conditioning, and pollination.
A new method developed by evolutionary biologists improves current species delineation methods and can help determine the threatened status of species. The DELINEATE approach models the speciation process, allowing researchers to understand how populations evolve into distinct species.
MIT researchers have generated the most accurate gene annotation of the SARS-CoV-2 genome, confirming six new protein-coding genes and discovering a rare gene-within-a-gene. The study also analyzed over 1,800 mutations, revealing regions that may help the virus evade the immune system.
A comprehensive study of the legume family reveals a history of whole-genome duplications and helps uncover the evolution of genes involved in nitrogen fixation. The research team identified strong evidence for 28 separate whole-genome duplication events, shedding light on the evolutionary spread and diversification of legumes.
A new bonobo genome assembly has been created with high accuracy, allowing for precise comparisons to other great apes and humans. The study reveals over 5,500 structural variants that distinguish the bonobo and chimpanzee lineages, providing insights into gene evolution and species divergence.
Researchers reconstructed the SARS-CoV-2 progenitor genome, finding it was circulating worldwide months before the first reported cases of COVID-19 in China. The team's findings provide a genetic common ancestor to all current infections and could aid molecular epidemiology detective work.
Researchers reconstructed Pinus genus evolutionary history using 1,662 genes, revealing 90% species originated in Miocene and midlatitude species are older than others. Environmental factors suggest topography drove pine diversification, with evidence of fire-adaptation syndromes over time.
Researchers have sequenced high-quality genomes for 16 vertebrate species, revealing new avenues for increasing immune defenses against emerging diseases. The study also standardizes genome assembly quality metrics using novel algorithms, paving the way for thousands of future genome assemblies.
Researchers found that corals' ability to grow calcium carbonate skeletons evolved between 308 and 265 million years ago, with necessary proteins present in their soft-bodied ancestors. The team identified genes responsible for transporting calcium and removing protons, as well as an acid-rich protein involved in skeleton building.
Researchers Constantina Theofanopoulou and Erich Jarvis demonstrate that the human hormone oxytocin is the same gene across all major vertebrate lineages, finding synteny in the hormone's receptor. They advocate for a new standard nomenclature to make life easier for scientists studying oxytocin and other hormones.
A new study proposes a universal nomenclature for oxytocin and vasotocin genes, which were previously named differently in various species due to small protein coding differences. The researchers found that both hormones stem from a common ancestral gene and propose a new naming convention based on this evolutionary history.
The Vertebrate Genomes Project has produced 16 diploid high-quality vertebrate reference genome assemblies, showcasing technological improvements and standardization for genomics. These assemblies enable unprecedented novel discoveries in biodiversity, conservation, and human health and disease.
Researchers at Stanford University have developed a new technique to analyze the genomes of archaic humans, revealing key differences in gene expression that may lead to physical traits. The study found associations with the vocal tract and cerebellum, suggesting rapid evolution of these organs in modern humans.
The study unravels the evolutionary and genetic origins of flatfish specialized body plan through comparative genomic analysis. Key findings include significant alteration in genes related to visual perception, immune response, and musculature development.
A team of scientists from China has sequenced the high-quality genome of Chinese hazelnut, identifying genes related to oil biosynthesis and stress resistance. The study provides valuable resources for molecular breeding and genetic improvement of hazelnut crops worldwide.
A study of marten genomes reveals that coastal refugia in Alaska and Canada may have provided resources for human migrants, aiding the peopling of the Americas. The research found a deep history for Pacific martens along the North Pacific Coast, dating back to the Last Glacial Maximum.
Recent genomic analyses reveal that bird genomes contain fewer tRNA genes compared to other vertebrates, yet exhibit similar usage patterns. The authors found that the contraction in tRNA genes is balanced by preferences for certain isoacceptor families, ensuring optimal translational efficiencies.
Researchers from Uppsala University discovered a new species of bumblebee, Bombus incognitus, through genetic analysis of Rocky Mountains samples. The study reveals potential for speciation in arctic and alpine environments due to climate change.
New study reveals that whales and hippos developed unique skin traits for aquatic life, contradicting current dogma. Genetic analysis shows that these traits evolved independently in both groups, with cetaceans losing more skin genes than hippos.
Researchers at the University of Florida have discovered a way to evaluate enzyme lifespan, allowing them to identify enzymes that need improvement. This breakthrough could lead to increased crop yields by reducing energy spent on replacing worn-out enzymes.
Studies on viral evolution reveal that beneficial mutations often occur at the expense of symptom severity, while genetic novelties can arise from noncoding DNA insertion. Additionally, viruses' codon usage is constrained by host machinery, with some exhibiting unique compositions, and their effects can persist after infection clearance.
Researchers from the University of Copenhagen have studied the giraffe's genome, discovering a key gene FGFRL1 that enables its extraordinary features, such as high blood pressure and dense bones. The study also found that giraffes spend less time sleeping than other mammals due to their unique circadian rhythm regulation.
The study found that SARS-CoV-2 underwent little significant genetic change in the first year of the pandemic, suggesting a 'generalist' nature and rapid transmission. This is attributed to human population immunity and lack of containment, allowing the virus to spread quickly.