Articles tagged with Genotypes
A study of 286 patients with mild to moderate Alzheimer's disease found that treatment response to Aricept was not predicted by ApoE4 genotype or gender. Patients treated with Aricept showed significant improvements in global function and cognition, while those on placebo experienced decline.
Research reveals a strong interaction between neuroticism and the serotonin transporter gene in influencing cigarette smoking behavior. Individuals with poorly expressed serotonin transporter genotypes and high levels of neuroticism face significant challenges in quitting smoking. This study suggests personalized approaches to smoking ...
A study found that genetic variations can cause individuals to be more resistant to a cholesterol-lowering diet or at greater cardiovascular risk from a high-fat diet. Apolipoprotein B gene polymorphisms were associated with increased plasma total cholesterol concentrations in certain genotypes.
The study found that people with the 4/4 variant are 15 times more likely to develop Alzheimer's disease than those with the 3/3 variant. In contrast, individuals with the 2/3 genotype appear to be protected from developing AD due to the presence of the protective 2 allele.