Researchers at KAUST have developed NanoRanger, an accurate and rapid method for genetically diagnosing Mendelian genetic disorders. This breakthrough enables diagnosis in just 12 minutes, providing a detailed picture of the genomic disorder.
A new plant gene drive system, CRISPR-Assisted Inheritance (CAIN), has been developed to enhance trait inheritance in plants. The system uses a toxin-antidote mechanism to override Mendelian inheritance, allowing for the spread of beneficial genes at higher rates.
Researchers found a genetic link between higher circulating levels of arachidonic acid and lower risk for bipolar disorder. The study suggests that altering arachidonic acid synthesis pathways may reduce bipolar disorder risk, particularly in those with compromised pathways.
A recent study published in Nature has discovered several new disease genes and provided new insights into the effects of known genetic factors on disease. The study highlights an underappreciated complexity in dosage effects of genetic variants, challenging traditional Mendelian inheritance laws.
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A team of scientists has uncovered new information about Mendel's work, revealing that he began with practical objectives as a plant breeder before exploring underlying biological processes. This work laid the foundation for modern genetics and was only recognized 34 years after its publication.
Researchers have discovered a selfish genetic element, known as Segregation Distorter (SD), that skews genetic inheritance. SD has caused dramatic changes in chromosome organization and genetic diversity, leading to the accumulation of deleterious mutations.
A NUS study highlights the crucial role of maternal genes in genetic diseases in children, shedding new light on previously unsolved conditions. The researchers found that SMCHD1 protein from mothers controls gene expression in offspring, leading to skeletal defects.
A new translation of Mendel's 1866 paper reveals a more engaged and influenced scientist, with connections to contemporary theories of evolution. The work offers insights into the creation of genetics and challenges long-held debates among philosophers and historians.
Researchers found a gene called R2d2 that breaks Gregor Mendel's century-old 'law of segregation', leading to unequal inheritance of genes in mammals. This discovery has wide-ranging implications for fields like evolutionary genetics, biomedical science, and infectious diseases.
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Researchers found that Arabidopsis thaliana plants exhibit genetic traits from older generations, contradicting Mendelian inheritance. New experiments support these findings, providing evidence for novel DNA-based genetic phenomena and implications for plant biology and agriculture.
Researchers from Jena and Prague reveal that four scientists 'rediscovered' Mendel's laws in 1900: Hugo de Vries, Carl Correns, Erich von Tschermak-Seysenegg, and Armin von Tschermak-Seysenegg. New correspondence has corrected the traditional view of genetics' early history.
The article argues that Darwin's background and research focus prevented him from interpreting the evidence for Mendelian inheritance. Mendel's work was rediscovered in the 20th century, revealing that his understanding of biology far surpassed Darwin's.
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Purdue University researchers discovered that some plants can revert to normal traits carried by their grandparents, bypassing genetic abnormalities carried by both parents. This challenges accepted scientific beliefs and may prompt textbook revisions.