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Pioneering technique transforms genetic disorder diagnoses

Researchers at KAUST have developed NanoRanger, an accurate and rapid method for genetically diagnosing Mendelian genetic disorders. This breakthrough enables diagnosis in just 12 minutes, providing a detailed picture of the genomic disorder.

SourceKing Abdullah University of Science & Technology (KAUST)·JournalMed·DateJul 23, 2024

Researchers develop plant gene drive system for enhanced trait inheritance

A new plant gene drive system, CRISPR-Assisted Inheritance (CAIN), has been developed to enhance trait inheritance in plants. The system uses a toxin-antidote mechanism to override Mendelian inheritance, allowing for the spread of beneficial genes at higher rates.

SourceChinese Academy of Sciences Headquarters·JournalNature Plants·TypeExperimental study·DateJun 17, 2024

An omega-6 fatty acid may reduce the risk for bipolar disorder

Researchers found a genetic link between higher circulating levels of arachidonic acid and lower risk for bipolar disorder. The study suggests that altering arachidonic acid synthesis pathways may reduce bipolar disorder risk, particularly in those with compromised pathways.

SourceElsevier·JournalBiological Psychiatry·TypeComputational simulation/modeling·DateApr 30, 2024
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Proof that Mendel discovered the laws of inheritance decades ahead of his time

A team of scientists has uncovered new information about Mendel's work, revealing that he began with practical objectives as a plant breeder before exploring underlying biological processes. This work laid the foundation for modern genetics and was only recognized 34 years after its publication.

SourceJohn Innes Centre·JournalNature Genetics·TypeData/statistical analysis·DateJul 11, 2022

‘Supergene’ wreaks havoc in a genome

Researchers have discovered a selfish genetic element, known as Segregation Distorter (SD), that skews genetic inheritance. SD has caused dramatic changes in chromosome organization and genetic diversity, leading to the accumulation of deleterious mutations.

SourceUniversity of Rochester·JournaleLife·DateJul 6, 2022

NUS research brings new light to unsolved genetic diseases in children

A NUS study highlights the crucial role of maternal genes in genetic diseases in children, shedding new light on previously unsolved conditions. The researchers found that SMCHD1 protein from mothers controls gene expression in offspring, leading to skeletal defects.

SourceNational University of Singapore·JournalNature Communications·TypeExperimental study·DateJun 29, 2022
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New translation opens a window into the world of the 'father of genetics'

A new translation of Mendel's 1866 paper reveals a more engaged and influenced scientist, with connections to contemporary theories of evolution. The work offers insights into the creation of genetics and challenges long-held debates among philosophers and historians.

SourceUniversity of Exeter·JournalBulletin of the British Society for the History of Science·DateJan 30, 2017

Defying the laws of Mendelian inheritance

Researchers found that Arabidopsis thaliana plants exhibit genetic traits from older generations, contradicting Mendelian inheritance. New experiments support these findings, providing evidence for novel DNA-based genetic phenomena and implications for plant biology and agriculture.

SourceFaculty of 1000·JournalF1000Research·DateFeb 4, 2013

Early history of genetics revised

Researchers from Jena and Prague reveal that four scientists 'rediscovered' Mendel's laws in 1900: Hugo de Vries, Carl Correns, Erich von Tschermak-Seysenegg, and Armin von Tschermak-Seysenegg. New correspondence has corrected the traditional view of genetics' early history.

SourceFriedrich-Schiller-Universitaet Jena·DateMay 3, 2011

Why didn't Darwin discover Mendel's laws?

The article argues that Darwin's background and research focus prevented him from interpreting the evidence for Mendelian inheritance. Mendel's work was rediscovered in the 20th century, revealing that his understanding of biology far surpassed Darwin's.

SourceBMC (BioMed Central)·JournalJournal of Biology·DateFeb 27, 2009
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