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Thirty years later: A reappraisal of Alzheimer’s disease risk in Japanese APOE-e4 homozygotes

Researchers at Niigata University conducted the first comprehensive reappraisal of Alzheimer's disease risk in Japanese APOE-e4 homozygotes, finding a substantially lower risk than previously cited estimates. The study suggests that the risk is comparable to estimates reported in large studies of people with European ancestry.

SourceNiigata University·JournalMolecular Neurodegeneration·DateJun 29, 2026