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The bee that would be queen

A team of researchers from Arizona State University has discovered evidence that honeybees use a phylogenetically old molecular cascade to develop queens and workers. The findings, published in PLoS ONE, show that the TOR pathway is directly linked to nutrient-induced development, enabling two distinct phenotypes to evolve.

Extra-aggressive form of idiopathic pulmonary fibrosis identified

A subset of patients with idiopathic pulmonary fibrosis (IPF) has been found to have a short duration of symptoms before diagnosis and an accelerated clinical course to end-stage disease. This 'rapid progressor' group is characterized by distinct gene expression patterns, which may lead to the development of new therapeutic interventions.

Other highlights in the March 1 JNCI

Researchers have created a new model to examine the process by which tumor cells develop an angiogenic phenotype, enabling them to grow rapidly. The study found that non-angiogenic tumor cells can switch to angiogenesis after several months, and that this switch is crucial for tumor growth and metastasis.

Phenotype is influenced by nature, nurture and noise

A new computer model shows that intrinsic noise and biochemical delays generate oscillations in gene regulation, explaining observed variability in cells. This fine-grain analysis also sheds light on why identical twins don't have identical fingerprints.

Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Finding the function of fish ferroportin

Researchers have identified ferroportin 1 as essential for normal iron cycling in zebrafish. This discovery sheds light on the importance of ferroportin 1 in maintaining iron homeostasis in humans. Understanding its function is crucial for developing effective treatments for iron-related disorders.

Microarrays as phenotype

Researchers used microarray data to determine the order of genes in a pathway that results in a particular phenotype. By analyzing the interactions between genes, they were able to reconstruct the pathway and prove that gene A comes before gene B.

Familiarity decides if wolf spider loves 'em or eats 'em

Female wolf spiders exhibit social recognition and memory, favoring familiar male phenotypes for mating. This behavior is linked to their experience during the pre-adult stage, with cannibalization rates among unfamiliar males being higher.

Drinks of the father

Researchers found that a father's maximum number of drinks consumed in 24 hours is associated with disruptive behavior disorders, early substance-use initiation, and early substance-related disorders in his children. The study suggests that this 'phenotype' could supplement diagnostic categories for alcohol dependence.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.