Articles tagged with Acquired Immune Deficiency Syndrome
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A new oral medication, valganciclovir, has been shown to be as effective as traditional intravenous treatment for CMV retinitis in AIDS patients. The pill form reduces the need for permanent catheters and improves patient convenience.
The University of Illinois Chicago College of Nursing has launched a five-year AIDS prevention project in Malawi, training health workers to become leaders in combating the pandemic. The project aims to educate hospital staff, nurses, and medical officers on HIV transmission and safe-sex practices, as well as mobilizing community peer ...
A cross-sectional study of 493 married couples in Thailand found that HIV transmission from men to women is significantly linked to increased viral loads among HIV-positive men. Women who had previously contracted an STD or used hormonal contraceptives were also at higher risk of transmission.
The SMART trial aims to find a balance between aggressive HIV treatment and minimizing adverse side effects. The study will compare two distinct treatment approaches over an average of seven years, providing valuable insights into the optimal use of antiviral therapy.
A Mayo Clinic case study describes a patient with progressive multifocal leukoencephalopathy (PML) who responded positively to HAART-cidofovir combination therapy, regaining mobility and daily functioning. The case contributes to growing data on effective treatment strategies for PML in AIDS patients.
Recent research from San Francisco Veterans Affairs Medical Center suggests a closer connection between HIV and Alzheimer's disease. The study found that immune cell markers of AIDS dementia remain even after treatment with anti-retroviral drug cocktails, similar to those elevated in patients with Alzheimer's disease.
A study found significant disparities in HIV/AIDS treatment among minority Medicaid recipients, with African Americans waiting longer to start life-saving treatments and Hispanics being less likely to stay on them. The researchers suggest that improved care strategies and supportive services are needed to address these disparities.
A recent study by Ohio State University researchers found that gay men tend to weigh the benefits and drawbacks of revealing their HIV status, with over half disclosing to family and 63% telling friends. The top reasons for disclosure included keeping others safe and seeking understanding.
A study of 633 HIV-positive participants found that sociodemographic factors significantly affect their nutritional adequacy. Gay men, those with higher household incomes and educational attainment, were more likely to meet the Recommended Daily Allowances for nutrients. In contrast, individuals with lower incomes, fewer children at ho...
Two reports on HBV infection shed light on the effectiveness of vaccination programs in reducing the disease rate and carrier state. A study found that 70% of carriers recovered within ten years after treatment, while a nationwide vaccination program for adults is crucial to prevent further transmission.
The study aims to determine the effectiveness of meditation and/or massage in improving patients' perceived quality of life. Researchers hope to find ways to improve quality of life, particularly in the spiritual domain, for patients dying with AIDS.
A new AIDS vaccine developed by Yale researchers has shown promising results in protecting monkeys from the disease. The vaccine, which uses a common livestock virus vector, was highly effective in animal models and protected vaccinated monkeys for up to 14 months.
A study finds that alcohol consumption is associated with unsafe sex among injection drug users, leading to increased HIV transmission risk. The research suggests that addressing alcohol use and disorders in this population is crucial for preventing the spread of HIV.
The collaboration between Myriad Genetics and the University of Utah revealed that the Tsg101 protein is essential for HIV1 budding, allowing for the disruption of the virus lifecycle. This breakthrough led to the identification of potential HIV drug targets, with lead compounds developed for anti-HIV therapy.
Dr. Anthony S. Fauci has been recognized for his significant contributions to understanding the regulation of the human immune response and the pathogenesis of HIV disease. He has developed effective therapies for formerly fatal diseases and has pioneered strategies for therapy and immune reconstitution of patients with AIDS.
A qualitative study of 32 people with HIV-1 or AIDS found that disintegration and loss of community are key factors driving desire for euthanasia and assisted suicide. The study suggests that clinicians must consider the complexity of patients' experiences when evaluating requests for physician-assisted suicide.
Researchers propose integrating highly-active antiretroviral therapy (HAART) into existing tuberculosis-control infrastructure in less-developed countries. Directly-observed therapy has shown effectiveness in resource-poor settings with sustained commitment to uninterrupted care that is free to the patient.
Researchers at the University of Maryland Biotechnology Institute have engineered rats to contain the genome of HIV-1, making them a valuable model for studying AIDS-related diseases. The rats develop clinical signs similar to those of AIDS in humans, including neurological abnormalities and organ damage.
A new study finds that a behavioral intervention program significantly reduces the incidence of risky sex behavior and transmission of HIV among HIV-positive men and women. The program, which included lessons on coping with HIV-related stress and promoting safer sex practices, led to increased condom use and reduced transmission rates.
Researchers found that HAART decreased the HIV death rate to 38 percent of pre-HAART levels and opportunistic infections to 66 percent, supporting its effectiveness in advanced patients. The study analyzed data from 528 advanced AIDS patients who received HAART for an average of 15 months.
The UNC-CH AIDS clinic in Robeson County offers treatment and care to HIV-positive patients near their homes, addressing a significant problem in the area's high sexually transmitted disease rates. The clinic is supported by a $100,000 grant and covers costs for indigent patients through Medicaid and private insurance.
A study published in the journal AIDS identifies a genetic risk factor for HIV infection, specifically a variation in the RANTES gene that increases susceptibility but also slows down disease progression. Researchers found that this SNP is associated with up to twice the risk of HIV infection and takes about 40% longer to develop AIDS.
A Cornell University parent-education program has shown that it can triple the likelihood of parents discussing HIV risk reduction with their children. The program also significantly increases the likelihood that parents will make personal risk behavior changes and obtain HIV testing. The study, which involved 375 parents in New York C...
Researchers at Beth Israel Deaconess Medical Center developed an AIDS vaccine that harnesses "killer" T cells to suppress the virus and prevent clinical disease in monkeys. The vaccine showed significant success in boosting CD8 cytotoxic T lymphocytes, which can attack and contain HIV-infected cells.
At the Institute of Human Virology (IHV) conference, scientists from Africa, Caribbean, and US/Europe discussed HIV/AIDS challenges in the developing world. They emphasized the need for more North-South partnerships to address affordable therapies and preventative vaccines.
Researchers from Emory University Health Sciences Center have identified three HIV-positive chimpanzees that are progressing to AIDS, offering insights into how the disease develops and may be resisted. The chimps' unique genetic profile could hold key to developing an HIV vaccine and new treatments for AIDS.
A new study at the University of North Carolina finds that men infected with HIV who use denial strategies to cope with the disease threat progress more rapidly to AIDS. Higher average blood levels of cortisol are also associated with faster progression.
A recent San Francisco study found that antiretroviral treatment continues to significantly improve AIDS patient survival rates, with a 60% reduction in risk of death for those receiving HAART. The study also revealed increased survival benefits over time, particularly among those diagnosed between 1996 and 1997.
Researchers found that women carry lower levels of HIV in their blood than men, especially during early phases of infection, but have the same risk as men of developing AIDS. Current guidelines may lead to more men being eligible for treatment due to lower viral load thresholds.
Researchers from UNC Chapel Hill present new approaches to HIV vaccine development, improved diagnostic training, and a method for identifying high-HIV transmission areas. They also reveal the role of Epstein-Barr virus in mouth disorders associated with AIDS.
Over 5,000 experts worldwide support the Durban Declaration, stating that HIV is the cause of AIDS and urging governments to focus on prevention efforts. The declaration aims to eliminate misinformation and mobilize the world to combat the devastating consequences of AIDS.
The Special Issue of Science documents the devastating impact of AIDS in sub-Saharan Africa, with 24.5 million HIV-infected people facing inaccessible treatments and preventive tactics. The article highlights the need for increased funding, estimated to be between $1.6 billion and $2.6 billion annually.
Research reveals that individuals coping with HIV/AIDS exhibit diverse information-seeking behaviors, from avoiding information to seeking out multiple sources. Understanding these complexities is crucial in developing effective treatment programs, as uncertainty can be a natural part of life for some individuals.
A study published in AIDS found an association between osteopenia and protease inhibitors, a class of medications used to treat HIV/AIDS. Researchers discovered that patients taking these medications were more likely to develop low bone-mineral density, which can lead to fractures.
People with AIDS-defining illnesses are at higher risk of developing memory loss and cognitive problems, including dementia. This poses a challenge for treatment adherence and overall public health.
AIDS patients with limited emotional support are more likely to be nonadherent to their medication regimens. Confidence and social support significantly predict medication adherence, suggesting interventions should focus on enhancing these factors.
A preliminary study found that 38% of HIV-positive people in low-income hotels took over 90% of their medication, adhering well to combination anti-viral therapy. The researchers also discovered a close relationship between medication adherence and viral suppression, with levels of HIV doubling for every 10% of missed pills.
The new facility will enable researchers to conduct major studies on HIV-1C, a subtype responsible for more than half of the world's infections. The lab aims to identify prevention and treatment strategies to combat the spread of this devastating virus in southern Africa.
Physicians at UNC-CH and Duke will receive funding to support care for people living with AIDS across North Carolina and clinical trials promising further medical progress. The renewed national Adult AIDS Clinical Trials Group (AACTG) funding reflects the quality of AIDS research and treatment in North Carolina.
Researchers found a consistent pattern of viral evolution in individuals who later progressed to full-blown AIDS, allowing for preclinical stage recognition. This prediction may help target therapies to prevent or slow disease progression.
The UCSF AIDS Research Institute is hosting a symposium to discuss strategies for preventing the second HIV epidemic. Experts will cover topics such as vaccine development, drug resistance, and post-exposure prevention.
A study by Rockefeller and Aaron Diamond researchers found that about one in six patients with the AIDS virus carried a strain resistant to at least one drug. The researchers recommend exploring the prevalence of this resistance and considering therapy structured around HIV-resistance testing to improve treatment effectiveness.
A 5.5-year study found that stressful events and low social support accelerate HIV progression to AIDS, with men who developed AIDS twice as likely to have experienced major depressions before onset.
Researchers at UNC Health Care found that men with high stress levels and weak social support developed AIDS faster. The study of 82 HIV-infected gay men showed that cumulative stressful events doubled the risk of progressing to AIDS.
Researchers found a significant link between HIV infections and abnormal vaginal bacteria in pregnant women. Four times as many subjects with bacterial vaginosis were HIV-infected compared to those with a normal balance.
A study reveals a dramatic rise in oral warts among HIV patients treated with protease inhibitors, which are effective against HIV. The researchers found that these warts were difficult to control and highly prone to recurrence, causing discomfort and affecting eating habits.
A study by Emory University infectious disease specialists found that most inner-city HIV patients hospitalized for HIV or AIDS had not received outpatient care or HAART therapy in six months prior. Despite the effectiveness of combination drug therapy, patients often fail to take advantage of available resources.
University of Illinois researcher Paula Treichler argues that popular culture and narrative can effectively engage the public about science. The AIDS storyline on ABC's General Hospital is cited as an example of this approach, which used a soap opera format to educate and explore the meanings of AIDS.
A UK allied health professor has received a patent to test the effectiveness of combining lithium salts with existing anti-viral drug agents for AIDS patients. The proposed treatment aims to reduce toxic side effects and enhance the immune system, potentially reducing the amount of virus in the body.
A peer-led intervention program, EachOne TeachOne, has shown success in reducing high-risk behaviors among drug users, with 80% of participants cutting back on their drug use or maintaining a low level of risk. However, condom use remained an area of concern, with only 25% of participants showing improvements.
Scientists identify a new pathway through which HIV can disturb the function of uninfected cells, leading to a sudden decline in immune function. The research suggests that blocking HIV binding to CXCR4 could stop advanced AIDS progression in patients with certain strains of the virus.
The Emory/Atlanta CFAR is a multidisciplinary research center focusing on the prevention and treatment of HIV/AIDS. With a $2.3 million grant, it aims to foster collaboration among diverse HIV/AIDS programs in Atlanta.
A new study by University of California San Francisco researchers proposes expanding federal Medicaid coverage of HIV drugs to control the disease. The expansion would result in 9,600 more years of life for persons with HIV disease over five-years and prevent 4,200 deaths.
A recent study published in Annals of Internal Medicine found that testosterone administration significantly increases lean body mass and improves the quality of life in men with AIDS wasting syndrome. The treatment was shown to produce significant term benefits, making it an important new therapy for patients with this condition.
Researchers investigated enteral supplements' impact on AIDS patients, finding net increases in protein and energy intakes. However, fat-free mass did not increase for the group as a whole, but was inversely correlated with baseline synthesis of fat.
A new vaginal microbicide, BufferGel, has shown promising results in a Phase I study, with 27 women reporting no serious side effects. The gel works by reducing the vaginal pH level, making it an effective barrier to HIV transmission.
Researchers found that 11% of infected men were long-term nonprogressors at 10 years, but only 2% remained nonprogressors after 18 years. High plasma viral loads are a strong predictor of disease progression. Antiviral therapy is recommended for individuals with rising virus levels and high CD4 counts.
The updated guidelines advocate for early, potent combination antiretroviral therapies to prevent AIDS in individuals infected with HIV. The new recommendations suggest that simpler drug regimens may offer greater compliance and convenience.
A study of Rhode Island's needle exchange program found that sharers reuse needles an average of 24 times, contributing to high HIV infection rates; providing clean needles is seen as the single most effective way to prevent its spread.
A major HIV prevention trial involving low-income women and men living in urban areas found that behavioral interventions can reduce HIV-related sexual risk. The study, which recruited 3,700 participants, showed significant improvements in condom use and reductions in unprotected sexual acts after a one-year intervention.