Researchers at Emory University Health Sciences Center discovered that non-pathogenic bacteria in the GI tract can block an immune system pathway called NF-KB, preventing cells from responding to potential threats. This mechanism may play a crucial role in the pathogenesis of inflammatory bowel disease and other intestinal diseases.
A recent study found that high levels of inflammation can impede the effectiveness of clot-busting treatment after a heart attack. Individuals with elevated C-reactive protein levels had slower responses to thrombolytic therapy, resulting in delayed revascularization and increased damage to the heart.
Researchers have discovered a new class of synthetic molecules that effectively inhibit inflammation by removing L-selectin proteins from the cell surface, preventing cells from sticking together. This approach offers a novel strategy for treating pain and swelling associated with injury or illness.