Articles tagged with Bacteria
A marine bacterium produces an organic detergent to attach to oil droplets, allowing it to feed on energy-rich chains. The synthetic pathway of this detergent involves three enzymes and has potential biotech applications for microbial production of key chemical compounds.
Researchers at the University of Würzburg have developed a new, efficient method for recording gene activity in bacteria. The MATQ-seq protocol achieves a high cell retention rate of 95% and detects the activity of 300 to 600 genes per bacterial cell.
Researchers have discovered that combining antibiotics with an enzyme called endolysin can protect against infection by resistant bacteria in all bodily organs, including the brain. This breakthrough could lead to a new treatment for meningitis, a life-threatening disease caused by resistant bacteria.
Researchers have developed a method to label and visualize the glycans in Mycobacterium tuberculosis cells, which may lead to faster and cheaper diagnostic tests for TB. The approach uses an organic molecule that reacts with specific sulfur-containing sugars found in only three bacterial species, including M. tuberculosis.
Researchers discovered how certain bacteria breathe by generating electricity, using a natural process that pushes electrons into their surroundings. This finding could enable new developments in clean energy and industrial biotechnology.
Scientists have engineered a new drug candidate to target the deadly Mycobacterium abscessus infection, which is growing threat among immunocompromised patients and those with certain lung diseases. The new findings offer a promising solution for cystic fibrosis patients who are most endangered by M. abscessus infections.
A new study by Virginia Tech researchers suggests that bacteriophages, or virus-like particles, may increase the sensitivity of gut bacteria to antibiotics. The team created a mouse model that allows them to control phage populations and found evidence that phages can exacerbate antibiotic damage.
A novel selective medium was developed to isolate Escherichia albertii, a previously uncharacterized species. The CT-PS-XR-MacConkey agar selectively differentiated E. albertii from other bacteria, including those in food samples. This finding has significant implications for the identification and study of this pathogen.
Researchers developed bacteria-enhanced graphene oxide nanoparticles that effectively destroy tumors through a three-pronged mechanism. The nanocomposites combine chemotherapy, immune activation, and photothermal heating to suppress tumor growth and activate strong immune responses in mice.
A new model predicts how bacteria navigate obstacles to spread, informing strategies for curbing infections or designing better drug delivery. The model focuses on three surface states: uninterrupted movement, sliding along surfaces, and getting stuck in corners.
Researchers discovered that sulfur bacteria from the Desulfobacteraceae family work together like a team to break down diverse organic compounds. By analyzing six strains, they found similar molecular strategies and a highly energy-efficient central metabolism pathway, enabling them to thrive in oxygen-free environments.
Researchers at the University of Basel have discovered that bacteria assemble their nanoweapons, known as type VI secretion systems (T6SS), in response to cell envelope damage. This rapid retaliation allows Pseudomonas aeruginosa to incapacitate attackers and thrive in diverse environments.
Scientists have uncovered the molecular structure of Mycoplasma mobile's twin motors that power its gliding ability, using cryo-electron microscopy. The complex structure reveals a new mechanism by which energy from ATP hydrolysis is converted into motility.
Researchers developed a synthetic microbiome therapy using limited strains of gut bacteria to effectively protect against C. difficile infections in mice. The treatment was as effective as traditional fecal transplants and had fewer safety concerns, offering a new alternative for treating this notoriously difficult-to-treat infection.
Researchers created laser-textured metal that stops bacteria from attaching, reducing biofilm buildup and making surface cleaning easier. The technique alters water-repellent properties of the metal, a key factor impacting bacterial growth.
Researchers identified a vulnerability in the bacterial machinery driving antibiotic resistance adaptation, which could lead to new counter-strategies. The study found that a genetic toolbox called integron system plays a crucial role in adapting resistance genes.
The winners of the Applied Microbiology International Horizon Awards 2024 have been named, including the One Health Microbiome Center at Penn State and researchers Dr. François Thomas and Dr. Helen Onyeaka.
Researchers have discovered two previously unknown bacterial species in deep-sea corals from the Gulf of Mexico. These bacteria have extremely reduced genomes and lack the ability to break down carbohydrates, surviving on amino acids instead. The discovery provides insights into the unique adaptations of deep-sea organisms.
A new study reveals how three species of bacteria coexist in biofilms by playing a game of 'nice' and then moving out when the surface becomes too crowded. The dominant species, Pseudomonas aeruginosa, disperses to allow other species to thrive.
A new study has identified novel strains of microbes that have adapted to use limited resources in cities, including those found in Hong Kong's subways and skin. These microbes can metabolize manufactured products, posing health risks if they are pathogenic.
Researchers at Japan Advanced Institute of Science and Technology have developed a novel method to culture antitumor bacteria using porous scaffolds, enhancing their anticancer properties and improving safety in animal testing. The approach resulted in improved survival rates in mice with breast cancer, including drug-resistant cases.
A team of researchers discovered a mechanism that determines the spiral shape of Rhodospirillum bacteria, revealing a novel link between cell shape and fitness. The study found that an outer membrane porin-lipoprotein complex modulates elongasome movement to establish cell curvature in R. rubrum.
Researchers discovered a non-virulent bacterium, Mycobacterium spongiae, that shares 80% of its genetic material with M. tuberculosis, shedding light on the disease's origins. The study provides valuable insights into the evolution and virulence of TB.
A team of researchers at UC Davis Health discovered a novel bioelectrical mechanism that allows Salmonella bacteria to navigate the gut lining and find vulnerable entry points. The study found that Salmonella bacteria detect electric signals in FAE, which helps them move towards openings in the gut where they can enter.
A $750,000 NIFA grant will support research on growing blackberries in soilless substrates to increase yields and improve fruit quality. The project aims to develop an integrated system for enhanced profitability and sustainability.
Researchers at ISTA discovered that misaligned protein filaments 'die' and re-assemble to form a well-aligned ring structure essential for bacterial cell division. This mechanism could lead to the development of synthetic self-healing materials.
A recent study revealed that specific bacteria produce a carbohydrate compound that induces settlement and metamorphosis in larvae of the warm-water tubeworm Hydroides elegans. This process, known as biofouling, can coat ship hulls and propellers, causing significant economic damage.
Researchers at the University of Illinois Chicago have developed a new dual-action antibiotic that targets two different cellular targets, making it nearly impossible for bacteria to evolve resistance. The antibiotic works by disrupting protein production and DNA structure, rendering random mutations ineffective.
Researchers found that rotifers acquire genes from bacteria and produce resistance weapons, such as antibiotics and antimicrobial agents. The team's findings suggest that rotifers could give important clues in the hunt for new antibiotics to treat human infections.
Researchers at MIT have developed a new way to make microbes hardy enough to withstand industrial processing, high temperatures, radiation, and long-term storage. The method involves mixing bacteria with food and drug additives, resulting in stable formulations that can be used in various applications.
Researchers found that disease transmission between farms persists despite movement restrictions, with cattle movement activities being the strongest predictor of farm infections. The study calls for a multifaceted approach to managing Salmonella Dublin, including closer monitoring and targeted interventions.
A new study by RIKEN CSRS shows that biomass from purple photosynthetic marine bacterium Rhodovulum sulfidophilum is an excellent nitrogen fertilizer, effective as inorganic synthetic fertilizers but with lower environmental side effects. The biomass boosts plant growth without altering soil pH or salinity.
Lopatkin's lab will investigate how bacterial metabolism contributes to antibiotic resistance using sophisticated tools and techniques. The research aims to identify drug-resistance mutations that arise in bacteria adapting to different antibiotics and metabolism-altering chemicals.
A recent study discovered a unique vaginal microbiome in patients with gynecological cancers, which could serve as a diagnostic biomarker. The researchers found a decrease in beneficial bacteria and an increase in potentially pathogenic microorganisms, leading to promising results for early detection.
A novel real-time PCR method has been developed to detect and identify the emerging zoonotic foodborne pathogen E. albertii, which is often misidentified as E. coli. The study found that E. albertii can survive in the human intestinal tract for approximately four weeks.
Researchers discovered that two species of marine bacteria work together to produce vitamin B12, essential for metabolism and survival of many marine organisms. The bacteria release building blocks into the water, which are then combined to form the vitamin through a complex process involving viral infection.
Scripps Research scientists have identified the role of polyphosphate in bacterial resting states, which can evade antibiotics. Blocking polyphosphate production may be an effective way to target slow-growing and non-growing phases of bacteria.
A study published in Cell reveals a detailed catalogue of bacteria living in cancer metastases, including links to therapy efficacy and tumor cell activity. The research provides new insights into how bacteria interact with cancer cells and their surroundings.
The study investigates microbial community and antibiotic resistance genes (ARGs) in the western Qinghai Lake basin. ARGs were found to be significantly lower than in strong anthropogenic activity areas, but a correlation with I1 was observed, indicating potential rapid proliferation.
Researchers at RIKEN found that gut bacteria, particularly Bifidobacterium, are associated with higher chances of successful milk-allergy treatment. However, only 7 out of 28 children who underwent oral immunotherapy passed the food challenge after a two-week milk avoidance period.
A team of researchers has developed a reliable method to define bacterial species and strains by analyzing genetic diversity. The study found that natural gaps in genetic diversity can be used to differentiate between species, with members of the same species showing high levels of genetic relatedness.
A novel antibody constant region variant (REW) extends plasma half-life and improves biodistribution, allowing for both invasive and non-invasive delivery. The REW technology also enhances the complement system, providing enhanced ability to kill cancer cells and bacteria.
Researchers at the Complexity Science Hub have isolated and genotyped Leptospira bacteria from Austrian cattle, revealing a widespread and adaptable strain that poses a public health risk. The study's findings highlight the need for improved diagnostic tests and biosecurity measures to prevent infection on farms.
Scientists discovered that bacteria form partnerships between different defence systems to create a formidable force against phage viruses. This discovery could lead to new strategies for combating antimicrobial resistance and developing phage therapy as an alternative to antibiotics.
Researchers from Osaka University found that gargling with an antiseptic mouthwash can reduce periodontitis-related bacteria in patients with type 2 diabetes. This simple method may improve the lives of people with periodontitis-linked diseases such as diabetes, dementia, and cardiovascular disease.
Researchers have developed a new search tool, microbeMASST, to study microbial metabolism, which could transform our understanding of human health and the environment. The tool instantly matches microbes to their metabolic signatures without prior knowledge.
Researchers discovered that a bacterial species can switch from being prey to a predator when grown at a lower temperature. The study, published in PLOS Biology, highlights the importance of considering historical context in evaluating predator-prey relationships.
Researchers at McMaster University have discovered a molecular barcode system used by disease-causing bacteria to distinguish between beneficial and toxic molecules. This discovery sheds light on the mechanisms underlying bacterial pathogenicity, allowing for potential biotechnology applications to combat infectious diseases like tuber...
Researchers at the University of Louisville are studying Yersinia pestis bacteria to better understand its ability to evade the immune system. The team hopes to develop new ways to control infectious diseases, including plague and other lung infections.
Researchers have discovered that natural antimicrobial predatory bacteria, Bdellovibrio bacterivorous, produce fibre-like proteins on their surface to ensnare prey. This breakthrough enables scientists to use these predators to target and kill problematic bacteria in healthcare, food spoilage, and the environment.
A new study using Raman spectroscopy has identified Pseudomonas bacteria from turtle skin in just 5-30 minutes, offering a faster alternative to traditional methods. The technique provides detailed information about bacterial chemical structure and holds great potential for future research on other microorganisms.
A study published in Molecular Cell describes how bacteria build a form of ubiquitin that helps cells communicate. The research sheds light on how different enzymes impact this protein during infection, providing an important first step towards understanding its role in diseases like Parkinson's and breast cancer.
Researchers discovered that short- and long-range weapons perform differently depending on the competition scenario, with long-range toxins becoming effective at high density and low initial numbers of competing bacteria. This study could help engineer beneficial microorganisms to out-compete pathogenic strains.
The study analyzed 170 known bacterial languages, grouping them into clusters based on molecular structure. Bacteria can understand related languages, but not those with vastly different languages. This understanding will aid in refining treatment approaches and developing biotechnology applications.
Research identifies specific gut bacteria that increase risk of severe malaria in humans and mice, sparking new approaches targeting gut microbiota. The study's findings could lead to prevention strategies for severe malaria-related deaths.
Researchers found that Wolbachia pientis infection restores fruit fly fertility, enabling them to produce more offspring than uninfected flies. This discovery has significant implications for controlling insect populations and range, potentially increasing mosquito populations that do not carry human diseases.
A new study confirms the presence of deadly Vibrio bacteria in Florida's coastal waters following Hurricane Ian. The research, led by University of Maryland senior author Rita Colwell, found high levels of pathogenic Vibrio parahaemolyticus and Vibrio vulnificus, particularly in oyster samples from Lee County.
Researchers have discovered a novel enzyme family related to bacterial pathogenicity in Gram-negative bacteria. The study revealed that enzymes involved in OPG synthesis and regulation play crucial roles in bacterial infection capability.
A study found that Acinetobacter baumannii and Candida auris were common among patients receiving mechanical ventilation, particularly in long-term care facilities. These pathogens pose a significant risk to this vulnerable population, highlighting the need for targeted surveillance and prevention efforts.
Researchers identified PUCH, a novel enzyme that produces small molecules called piRNAs to detect and prevent parasitic DNA from replicating in our genomes. This discovery sheds light on how our immune system works and may have implications for understanding innate immunity.