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Multiple sclerosis: Triggers in the gut flora

A study of twins reveals that certain bacteria in the small intestine may trigger MS. Researchers identified two specific bacteria, Lachnoclostridium sp and Eisenbergiella tayi, which are associated with the disease. The findings suggest a new potential therapeutic target for MS treatment.

SourceMax-Planck-Gesellschaft·JournalProceedings of the National Academy of Sciences·DateJun 5, 2025

Bacteria hitch a ride on yeast puddles to zoom around

Researchers discovered that bacteria can utilize fluid pockets created by yeast cells to speed up their movement and spread. This new mechanism reveals a key role for physical properties in microbial interactions, potentially enhancing bacterial colonization of environments with limited moisture.

SourceCell Press·JournalBiophysical Journal·TypeExperimental study·DateJun 4, 2025

New molecular label could lead to simpler, faster tuberculosis tests

Researchers have developed a method to label and visualize the glycans in Mycobacterium tuberculosis cells, which may lead to faster and cheaper diagnostic tests for TB. The approach uses an organic molecule that reacts with specific sulfur-containing sugars found in only three bacterial species, including M. tuberculosis.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateMay 5, 2025

CDI scientists introduce new engineered drug candidate for Mycobacterium abscessus to save lives

Scientists have engineered a new drug candidate to target the deadly Mycobacterium abscessus infection, which is growing threat among immunocompromised patients and those with certain lung diseases. The new findings offer a promising solution for cystic fibrosis patients who are most endangered by M. abscessus infections.

SourceHackensack Meridian Health·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMay 1, 2025

Development of a novel modified selective medium cefixime–tellurite-phosphate-xylose-rhamnose MacConkey agar for isolation of Escherichia albertii and its evaluation with food samples

A novel selective medium was developed to isolate Escherichia albertii, a previously uncharacterized species. The CT-PS-XR-MacConkey agar selectively differentiated E. albertii from other bacteria, including those in food samples. This finding has significant implications for the identification and study of this pathogen.

SourceOsaka Metropolitan University·JournalInternational Journal of Food Microbiology·DateApr 11, 2025

New model predicts how bacteria navigate obstacles to spread

A new model predicts how bacteria navigate obstacles to spread, informing strategies for curbing infections or designing better drug delivery. The model focuses on three surface states: uninterrupted movement, sliding along surfaces, and getting stuck in corners.

SourceSimons Foundation·JournalProceedings of the National Academy of Sciences·TypeComputational simulation/modeling·DateMar 21, 2025

Synthetic microbiome therapy suppresses bacterial infection without antibiotics

Researchers developed a synthetic microbiome therapy using limited strains of gut bacteria to effectively protect against C. difficile infections in mice. The treatment was as effective as traditional fecal transplants and had fewer safety concerns, offering a new alternative for treating this notoriously difficult-to-treat infection.

SourcePenn State·JournalCell Host & Microbe·TypeObservational study·DateMar 3, 2025

Deep-sea corals are home to previously unknown bacteria with extremely small genomes

Researchers have discovered two previously unknown bacterial species in deep-sea corals from the Gulf of Mexico. These bacteria have extremely reduced genomes and lack the ability to break down carbohydrates, surviving on amino acids instead. The discovery provides insights into the unique adaptations of deep-sea organisms.

SourceUniversity of Oldenburg·JournalNature Communications·TypeObservational study·DateNov 4, 2024

New bacteria-based therapy shows promise for fighting cancer

Researchers at Japan Advanced Institute of Science and Technology have developed a novel method to culture antitumor bacteria using porous scaffolds, enhancing their anticancer properties and improving safety in animal testing. The approach resulted in improved survival rates in mice with breast cancer, including drug-resistant cases.

SourceJapan Advanced Institute of Science and Technology·JournalChemical Engineering Journal·DateOct 15, 2024

What turns bacteria into spirals?

A team of researchers discovered a mechanism that determines the spiral shape of Rhodospirillum bacteria, revealing a novel link between cell shape and fitness. The study found that an outer membrane porin-lipoprotein complex modulates elongasome movement to establish cell curvature in R. rubrum.

SourceMax-Planck-Gesellschaft·JournalNature Communications·DateOct 7, 2024

Gut bioelectricity provides a path for bad bacteria to cause diseases

A team of researchers at UC Davis Health discovered a novel bioelectrical mechanism that allows Salmonella bacteria to navigate the gut lining and find vulnerable entry points. The study found that Salmonella bacteria detect electric signals in FAE, which helps them move towards openings in the gut where they can enter.

SourceUniversity of California - Davis Health·JournalNature Microbiology·TypeExperimental study·DateAug 20, 2024

Align or die

Researchers at ISTA discovered that misaligned protein filaments 'die' and re-assemble to form a well-aligned ring structure essential for bacterial cell division. This mechanism could lead to the development of synthetic self-healing materials.

SourceInstitute of Science and Technology Austria·JournalNature Physics·TypeComputational simulation/modeling·DateAug 12, 2024

Current strategies ineffective in controlling Salmonella Dublin in Danish cattle

Researchers found that disease transmission between farms persists despite movement restrictions, with cattle movement activities being the strongest predictor of farm infections. The study calls for a multifaceted approach to managing Salmonella Dublin, including closer monitoring and targeted interventions.

SourceComplexity Science Hub·JournalJournal of Dairy Science·TypeData/statistical analysis·DateJul 5, 2024

Marine bacteria team up to produce a vital vitamin

Researchers discovered that two species of marine bacteria work together to produce vitamin B12, essential for metabolism and survival of many marine organisms. The bacteria release building blocks into the water, which are then combined to form the vitamin through a complex process involving viral infection.

SourceUniversity of Oldenburg·JournalNature·TypeExperimental study·DateMay 8, 2024

Bacteria in cancer unmasked

A study published in Cell reveals a detailed catalogue of bacteria living in cancer metastases, including links to therapy efficacy and tumor cell activity. The research provides new insights into how bacteria interact with cancer cells and their surroundings.

Gut bacteria important for overcoming milk allergy

Researchers at RIKEN found that gut bacteria, particularly Bifidobacterium, are associated with higher chances of successful milk-allergy treatment. However, only 7 out of 28 children who underwent oral immunotherapy passed the food challenge after a two-week milk avoidance period.

SourceRIKEN·JournalAllergology International·DateMar 14, 2024

Gargling away the bad bacteria in type 2 diabetes

Researchers from Osaka University found that gargling with an antiseptic mouthwash can reduce periodontitis-related bacteria in patients with type 2 diabetes. This simple method may improve the lives of people with periodontitis-linked diseases such as diabetes, dementia, and cardiovascular disease.

SourceOsaka University·JournalScientific Reports·TypeObservational study·DateFeb 14, 2024

McMaster researchers discover molecular ‘barcode’ used by bacteria to secrete toxins

Researchers at McMaster University have discovered a molecular barcode system used by disease-causing bacteria to distinguish between beneficial and toxic molecules. This discovery sheds light on the mechanisms underlying bacterial pathogenicity, allowing for potential biotechnology applications to combat infectious diseases like tuber...

SourceMcMaster University·JournalProceedings of the National Academy of Sciences·DateJan 8, 2024