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Study sheds new light on the link between oral bacteria and diseases

Researchers at Karolinska Institutet have identified the most common bacteria found in severe oral infections, shedding new light on the association between oral health and systemic diseases. The study found that certain bacterial infections can spread to other parts of the body, highlighting the importance of understanding the role of...

SourceKarolinska Institutet·JournalMicrobiology Spectrum·TypeObservational study·DateNov 24, 2022

New study explains link between diabetes and UTIs

Research at Karolinska Institutet shows that people with diabetes have lower levels of psoriasin, a key peptide that weakens the bladder's protective barrier function. This increases the risk of urinary tract infections. Oestrogen therapy may help regulate the immune response to UTIs in patients with diabetes.

SourceKarolinska Institutet·JournalNature Communications·TypeExperimental study·DateSep 20, 2022

Novel compounds discovered in marine sponge can kill drug-resistant bacteria

Brazilian researchers have identified bioactive compounds in a marine sponge that killed antibiotic-resistant bacteria, paving the way to develop new drugs. The substances proved capable of eliminating bacteria such as Escherichia coli and Staphylococcus aureus, which are responsible for many hospital-acquired infections.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalJournal of Natural Products·DateJul 13, 2022

Fast and facile synthesis of antibacterial amino acid Schiff base copper complexes

Researchers at Tokyo University of Science have developed a fast and facile synthesis method for antibacterial amino acid Schiff base copper complexes using microwave irradiation. The new technique produces high-purity products with promising antimicrobial activity, overcoming the challenge of long synthesis times.

SourceTokyo University of Science·JournalApplied Microbiology·TypeExperimental study·DateJul 4, 2022

Coughing mice and the fight against pertussis

A team of researchers from Osaka University successfully established a mouse model that can reproduce the severe and persistent cough of pertussis. They found that pertussis toxin, Vag8, and lipooligosaccharide are key bacterial factors involved in inducing coughing, which ultimately leads to bradykinin and TRPV1 signaling.

SourceOsaka University·JournalmBio·TypeExperimental study·DateMar 31, 2022

Novel therapeutic strategy shows promise against pancreatic cancer

Scientists at Albert Einstein College of Medicine have developed a novel therapeutic strategy that uses bacteria to deliver tetanus toxin into pancreatic tumor cells, inducing an immune response and killing the cancer. The treatment has shown promise in reducing cancer metastases by 87% and increasing mouse lifespan by 40%.

SourceAlbert Einstein College of Medicine·JournalScience Translational Medicine·TypeObservational study·DateMar 23, 2022

Danish researchers discover new hiding place for antibiotic resistance

Researchers at the University of Copenhagen have discovered that resistant bacteria can hide resistance genes in inactive bacteria within biofilms, creating a reservoir of resistance that can be drawn upon when antibiotics are not present. This new understanding challenges the long-held assumption that resistant bacteria lose their res...

SourceUniversity of Copenhagen - Faculty of Science·Journalnpj Biofilms and Microbiomes·DateDec 16, 2021

Warning over antibiotic-resistant bacteria

A study by Anglia Ruskin University has identified potentially dangerous Pseudomonas bacteria in 21% of wild bird faeces collected from locations near the River Cam. The bacteria, which can be passed on to humans through cross-contamination, were resistant to multiple antibiotics.

SourceAnglia Ruskin University·JournalEcology and Evolution·DateNov 17, 2021

New group of antibacterial molecules identified

Researchers at Karolinska Institutet have discovered a new group of small antibacterial compounds that inhibit the formation of bacterial cell walls, showing promise against antibiotic-resistant strains. The molecules work by binding to lipid II, a crucial molecule for bacterial cell wall construction.

SourceKarolinska Institutet·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateNov 17, 2021