Researchers used medaka fish, CRISPR and new imaging techniques to study embryonic mitosis. They discovered unique spindles assemble in early embryos and found Ran-GTP plays a decisive role in spindle formation, which diminishes later in development. The study paves the way for further exploration of embryonic mitosis.
Researchers at Max Planck Institute for Biological Intelligence have discovered a brain circuit that inhibits food intake during nausea. The circuit involves special nerve cells in the amygdala, which send appetite-suppressing signals to distant brain regions, resulting in a loss of appetite.
Climate change exacerbates antimicrobial resistance by increasing global temperatures, sea levels, and disease transmission. This threat multiplier effect poses significant risks to human health, food supply, and ecosystem integrity.
Researchers at Utah State University have made significant contributions to sustaining human exploration on Mars by successfully growing plants in Martian conditions. The team's foundational research has been honored with a NASA Achievement Award.
A study by Ohio State University professor Scott Hayes found that incorporating five-minute exercise breaks into lectures can improve students' attention, motivation, and peer engagement. Students reported positive impacts on their course enjoyment and even designed creative exercise sessions, such as a 'picking apples' theme.
A new Northwestern Medicine study reveals that 73% of children with skin diseases face stigma and bullying, leading to impaired relationships and mental health issues such as depression and anxiety. The study suggests that clinicians should aggressively treat skin disorders in children and consider referral to evaluation and counseling.
A recent study published in JAMA Network Open found that understaffed nursing homes in disadvantaged neighborhoods are more likely to overmedicate residents with antipsychotics. The researchers suggest that increasing staffing levels could help reduce the use of these medications and address the root causes of behavioral issues.
A new study reveals that a single hurricane can wipe out 5-10% of New England's total aboveground forest carbon through tree damage. The research team analyzed the impact of 10 powerful hurricanes on the region's forests and found that future storms could pose a significant risk to carbon offset programs.
A new study assesses cognitive impairment over time in adults with essential tremor, finding a cumulative prevalence of 26.6% for mild cognitive impairment (MCI) and 18.5% for dementia. Early detection is crucial to slow further cognitive decline and improve quality of life.
Researchers developed a comprehensive modeling method to predict energy losses during hurricanes. The U.S.-Caribbean super grid configuration showed the highest power reliability increase. The study has broad implications for renewable integration and U.S. energy independence from fossil fuels.
A global team of researchers, led by the Royal Botanic Gardens, Kew, sequenced DNA from over 9,500 species, creating a detailed tree of life for flowering plants. The study sheds light on plant evolution, conservation strategies and sustainable agriculture applications.
Researchers explore how improving sleep can boost health for adolescents and young adults affected by racism. Sleep-promoting programs have been shown to improve developmental outcomes and disrupt the negative effects of racism on mental health, physical health, and academic outcomes.
Researchers at The University of Manchester have successfully achieved robust superconductivity in high magnetic fields using a newly created one-dimensional system. This breakthrough holds profound potential for advancements in quantum technologies, particularly in the quantum Hall regime.
The study reveals that TM4SF19 protein inhibits a pump in lysosomes, impeding macrophage clearance of dead cells. Macrophages lacking TM4SF19 demonstrate enhanced efficacy in clearing dead adipocytes, reducing weight gain and metabolic dysfunction. The findings may open new avenues for treating obesity and related metabolic disorders.
Scientists have isolated giant viruses that infect the deadly human parasite Naegleria fowleri, which causes primary amoebic meningoencephalitis. The newly discovered Naegleiaviruses were found in wastewater treatment plants near Vienna and exhibit a unique stargate structure for DNA entry.
Research shows breast cancer survivors are at increased risk of developing second cancers, including endometrial and ovarian cancer for women, and prostate cancer for men. Socioeconomic deprivation is linked to a greater risk of second cancers among breast cancer survivors.
A new AI math tutor, CAIT, will be integrated into the free digital learning platform ASSISTments to help middle-school students learn math while doing homework. The project aims to address the needs of students who have fallen behind in class but cannot afford private tutoring services.
An interdisciplinary team of scientists and engineers compared various aspects of running robots with their equivalents in animals, finding that biological components performed poorly compared to fabricated parts. However, animals excel in integrating and controlling these components.
A large study found a slightly increased risk of neuropsychiatric disorders among children exposed to prescription opioids during pregnancy, particularly at higher doses and longer durations. However, the researchers interpret this as clinically insignificant.
A Moffitt study reveals cells have a previously unknown information processing system that enables rapid adaptation and sophisticated communication. Ion gradients across the cell membrane form an information network for quick cellular decision-making, bypassing traditional genetic instruction.
A new study published in JAMA found X's Community Notes resulted in hundreds-of-millions of views of accurate and credible COVID-19 vaccine education, suggesting considerable potential for correcting misinformation. The notes typically addressed obvious misinformation, offering corrections from credible sources.
A study published in Neurology Clinical Practice found an association between the use of acid-reducing drugs and a higher risk of migraine. Researchers analyzed data from 11,818 people and found that those taking proton pump inhibitors were 70% more likely to have migraine.
Researchers developed a gene-based therapy that restored typical cellular function in organoids created from cells of people with Timothy syndrome. The treatment used antisense oligonucleotides to decrease the use of mutated exon 8A and increase reliance on non-affected exon 8, restoring normal calcium channel functioning.
A team of researchers created a single negatively charged lead-vacancy center in diamond, which emits photons with specific frequencies not influenced by the crystal's vibrational energy. This characteristic makes the PbV center a promising building block for large-scale quantum networks.
A new UK/German study suggests that perceptions of serious side effects are less than half as important as common side effects, such as fatigue or pain at the injection site, when making a decision to be vaccinated. The study found that educating the public about vaccine safety and efficacy is crucial in boosting vaccination uptake.
A new study by Chinese researchers has developed a high-energy-density aqueous battery using a mixed halogen solution as the electrolyte. The battery achieved a specific capacity of over 840 Ah/L and an energy density of up to 1200 Wh/L.
Researchers have developed a revolutionary method to quantify how well biomarker molecules bind to target proteins using super-resolution fluorescence microscopy. This technique enables spatially resolved proteomics, allowing for the analysis of individual proteins' behavior and quantity in cells.
A new study outlines the effects of temperature, humidity, and moisture content on molded fiber products' mechanical properties. The research provides mathematical models to describe these changes, helping improve MFP design and application.
A study published by the American Academy of Neurology found that immigrants to Canada who spend a greater proportion of their lives in the country have a higher risk of developing multiple sclerosis. The study involved 1.5 million immigrants and found that those who spent 70% of their lives in Canada were 38% more likely to develop MS.
Researchers at Stanford Medicine have developed brain organoids and assembloids to study neurodevelopmental disorders such as autism and schizophrenia. These three-dimensional models can survive for several years in culture, enabling scientists to view the developing human brain up close and in real time.
A study by Mount Sinai researchers has identified several pathophysiological mechanisms underlying perianal fistulae in Crohn’s disease. The findings highlight key transcription factor binding events and epigenetic phenomena that contribute to the higher rates of complications in African American patients. The research provides avenues...
A study by Uppsala University found that a computer game called Bad News improved students' ability to identify manipulative techniques in social media posts and distinguish reliable from misleading news. The game, played individually or in groups, had positive effects on students' critical thinking skills.
A recent study sheds light on the genetic underpinnings behind color polymorphism in adult females of cuckoo birds, revealing a single mutation for female-only polychromatism over 1 million years ago. The study found that variations in gray or rufous coloration are associated with the full length of the female-limited W chromosome.
Researchers at MIT's EQuS group demonstrate a method to generate highly entangled states and shift between types of entanglement, including volume-law entanglement. This breakthrough offers a way to characterize a fundamental resource needed for quantum computing, enabling better understanding of information storage and processing.
Grafting onto a disease-resistant rootstock reduces pathogenic Agrobacterium abundance and alters the microbiome composition, enriching beneficial bacteria. The decreased valine in root exudates from grafted plants contributes to decreasing Agrobacterium abundance and suppressing crown gall disease.
Contemporary US heart failure mortality rates have surpassed those in 1999 due to reversals from 2012 to 2021. The COVID-19 pandemic may have accelerated these increases, partly due to healthcare access limitations.
A study published in Nature reveals that oxidative dearomatization is the key mechanism behind this transformation, resulting in millions of diverse molecules with stable structures. This process allows the organic matter to persist for long periods, preventing it from rapidly returning to the atmosphere.
A team at KU Leuven has developed a TFT-based microprocessor that can be produced in two foundries, showcasing the potential of a 'foundry' business model for flexible electronics. The research demonstrates feasibility and paves the way for innovation in thin-film technology.
Research published in Global Change Biology indicates that a single hurricane can down 4.6–9.4% of New England's aboveground forest carbon. The study also shows that current carbon market policies are insufficiently buffered against the risks posed by hurricanes, which could lead to catastrophic emissions
Researchers at Penn State have made light effectively experience a magnetic field within a photonic crystal structure. This breakthrough could lead to more efficient lasers and other photonic technologies by increasing the interaction between light and matter.
A multidisciplinary research team has reconstructed the social dynamics of Avar-period steppe descent populations in Europe's Carpathian Basin. The study found that communities practiced a strict patrilineal system, with women playing a key role in promoting social cohesion through marriages outside their original community.
A team of researchers found that immune cells maintain their alertness through the JAK-STAT signalling pathway when there is no immediate threat. This discovery could lead to new approaches for enhancing the immune system's attention and preventing autoimmune diseases.
Researchers discovered that the SlTHM27-SlGAD2 model increases cold tolerance in tomatoes by regulating GABA levels and inducing anthocyanin biosynthesis. This study provides insights into improving cold tolerance in crops.
Researchers developed an AI technique to estimate brain age based on EEG scans, making early screening for degenerative brain diseases more accessible. The technology uses machine learning to analyze brain waves and can be used as a low-cost screening tool for large numbers of people.
A recent study found that infants born via C-section have more antibiotic-resistant genes, while antibiotic use and prematurity fuel resistance. Infants from Africa had more resistant genes than those from Europe. Probiotics may help reduce the spread of antibiotic resistance in infants by targeting their gut microbiome.
Researchers have found that temperature can affect mosquito longevity, infection time, and disease transmission. The study suggests that climate warming may increase malaria transmission in some areas but reduce it in others.
Researchers have found ancient rocks in Greenland that retain signatures of a magnetic field with a strength of at least 15 microtesla, extending the magnetic field's age by 200 million years. The discovery sheds light on the planet's early conditions and may have played a critical role in making Earth habitable.
Researchers at the University of Cambridge have developed low-cost light-harvesting semiconductors that power devices for converting water into clean hydrogen fuel using sunlight. By growing copper oxide crystals in a specific orientation, they improved performance by an order of magnitude and increased stability.
A study by Professor Graf-Vlachy's team found that CEOs with high levels of narcissism appoint managers who mirror their own traits, resulting in a 18% increase in narcissism among new hires. This leads to higher turnover rates and increased costs for companies.
Researchers developed a bioelectronic chip that can detect vitamins C and D in body fluids, offering a low-cost and easy-to-use solution for micronutrient monitoring. The chip is disposable, flexible, and can be adapted for wearable devices, enabling personalized diets and prevention of deficiencies.
A new study shows that firms in the US respond differently to political parties in charge, even if policies don't change. Firms located in Republican-governed states spend more on water pollution control than those in Democratic states.
Researchers found that spinal cord injury triggers abnormal neuronal activity that causes abdominal fat tissue compounds to leak and pool in the liver and other organs. A short course of gabapentin, commonly prescribed for nerve pain, prevented this damaging metabolic effect.
Researchers identified elevated MALAT1 levels in various blood cancers, correlating with adverse outcomes. MALAT1 promotes cancer cell proliferation, migration, invasion, and metastasis through multiple mechanisms.
Researchers from Qingdao Agricultural University have discovered the PsmiR159b-PsMYB65 module regulating bud dormancy release in tree peony. The study found that PsmiR159b inhibits bud dormancy release by targeting PsMYB65, which activates cell cycle genes and promotes bud growth.
Researchers have found that genetic mutations are not essential for cancer onset, and instead, epigenetic dysregulation plays a crucial role. Epigenetic changes can cause gene expression to be altered, leading to tumour formation even after the signal has been restored.
Scientists have recovered a 3.7-billion-year-old record of Earth's magnetic field, revealing it to be remarkably similar to today's field. The study provides the oldest estimate of the strength of Earth's magnetic field derived from whole rock samples.
MIT engineers have developed a closed-loop drug-delivery system that can improve chemotherapy outcomes by continuously monitoring patients and adjusting dosage. The new system, called CLAUDIA, uses commercially available equipment to analyze blood samples every five minutes and adjust infusion rates in real-time.
A UCLA-led study found large differences in language used to describe male and female suicides, with women more likely to have documented mental health conditions and received treatment. The study suggests using this 'language of suicide' to identify early warning signs for men.
A flexible microdisplay device can track and display neural activity in the brain, allowing neurosurgeons to visualize critical cortical boundaries and guide surgical interventions. The device reduces the need for a buffer zone, enabling more precise removal of harmful tissue.
Researchers analyzed ancient DNA data from 424 individuals to reconstruct Avar community structures and social dynamics. They found strict patrilineal descent systems, female exogamy, and levirate unions, suggesting females played a key role in promoting community cohesion.