A new study suggests that controlling eight key health risk factors can significantly reduce premature death risk in people with high blood pressure. By addressing these risk factors, researchers found a 40% lower risk of early death and up to 53% less risk of death due to cardiovascular disease.
Researchers designed a novel high-entropy metallic glass catalyst with intrinsic nanoscale phase separation, enabling selective dissolution and creating a three-dimensional nanoporous structure that remains amorphous. This results in abundant active sites and improved water splitting performance.
The DGIST research team has identified a molecular mechanism that coordinates the operation of NMDA glutamate receptors, key to regulating excitatory synapse function in the brain. This discovery provides clues for developing treatments for brain diseases such as autism spectrum disorders.
A study found that elevated blood eosinophil counts correlate with Pseudomonas aeruginosa infection in bronchiectasis patients. Inhaled tobramycin reduced symptom burdens and bacterial load without affecting BEC levels, suggesting a targeted therapeutic approach
SBI-810, a non-opioid treatment, activates a specific pain-relief pathway that avoids the euphoric high linked to addiction. The compound effectively relieved pain from surgical incisions and nerve injuries better than some existing painkillers.
Wiley adds new data to its KnowItAll Raman Spectral Library collection, bringing the total to over 27,000 spectra. This expansion enhances lab efficiency and accuracy through reliable spectral analysis.
Researchers have repositioned allopurinol to treat Marfan syndrome, a chronic debilitating disease affecting the cardiovascular, skeletal, and ocular systems. Treatment with allopurinol has shown to halt and prevent aneurysm progression and occurrence.
A new report reveals that over half of UK child sexual abuse survivors have not received support, highlighting a critical gap in local systems. The survey also found that many victims were first subjected to abuse at a young age and struggled with disclosure and healing.
People who sit for more than 14 hours a day may have a higher risk of cardiovascular events or death after treatment for heart attack symptoms. Replacing sedentary time with sleep reduces the risk, according to new research published in Circulation: Cardiovascular Quality and Outcomes.
New indicators have been introduced to Taylor & Francis journal articles to inform readers when cited research has been retracted or updated. These updates ensure researchers are fully informed about the status of the research and can make informed decisions.
Researchers developed a novel approach to trigger tumor pyroptosis using near-infrared light-activated carbon dots. The study bridges nanomedicine and immunotherapy, offering hope for metastatic and treatment-resistant cancers.
Nankai University has joined the Bentham Science Institutional Membership Program to publish its research as open access under CC-BY 4.0 license in various Bentham Science journals. The partnership aims to foster high-quality research and expand global access to scholarly knowledge.
Researchers Mohammad Afzal Shadab and Eric Hiatt developed a computer model that calculates the time it took for water on early Mars to percolate from the surface down to the aquifer, finding a 50-200 year timeframe. This process could have covered Mars with at least 300 feet of water.
Scientists have found a 2D semiconductor clay material with antiferromagnetic properties, which could be used in sustainable materials and technology. The material is cheap, easily available, and stable, making it an exciting discovery for the development of environmentally friendly quantum technologies.
Researchers at A.C.Camargo Cancer Center developed a more powerful version of CAR-T cells by inhibiting the epigenetic alterations that made them inefficient against non-Hodgkin's lymphoma and acute lymphoblastic leukemia. This modification resulted in improved treatment efficacy, tumor elimination, and reduced side effects.
US survivors of adolescence and young adult cancer experience significantly worse mental health outcomes into middle age and older adulthood. Cancer clinicians should acknowledge this mental health burden and take steps to address it.
A new DNA-based blood test using PhasED-Seq technology detects minimal residual disease (MRD) in B-cell malignancies, offering a powerful tool for early detection and monitoring treatment response. The assay demonstrates exceptional performance and high accuracy in detecting cancer cells in the bloodstream.
Researchers have made promising advancements in regenerative medicine for fibrotic endometrial disorders like IUA and TE. Transplanting mesenchymal stem cells into the endometrium can reduce fibrosis, stimulate angiogenesis, and improve pregnancy outcomes.
Researchers at DKFZ discovered that EBV-infected B cells exhibit characteristics of 'homing cells,' allowing them to migrate and target specific tissues. This process is controlled by viral proteins EBNA2 and LMP1, which increase the activity of pro-inflammatory cytokines.
DELERIA, a novel software platform, is being developed to support the GRETA spectrometer in nuclear physics experiments. The platform enables real-time data analysis, allowing researchers to make critical adjustments during the experiment, leading to faster and more accurate results.
The international conference will focus on translating phage research into clinical reality, exploring key sessions and major speakers. Companies from various sectors are attending the event, highlighting the growing interest in phage therapy.
Researchers have elucidated the molecular mechanism by which LEM-3 cuts DNA bridges during cytokinesis, a crucial step in cell division. The study found that LEM-3 is essential for resolving persistent DNA bridges and maintaining chromosomal stability.
Researchers developed a spherical prototype with adjustable surface dimples to cut through pressure drag and generate lift, reducing drag by 50% compared to smooth counterparts. The adaptive skin setup can adjust dimple depth to maintain drag reductions and generate controlled movement.
A new study presents a learning-free method for hip exoskeleton control, achieving seamless adaptation to continuous locomotion modes without user-specific data training. The proposed three-layer control framework ensures smooth transitions by predicting terrain changes before the end of transition periods.
Girls who enter puberty early have a higher BMI before, during, and after puberty, increasing the risk of overweight later in life. The study found that biological differences between sexes make girls more vulnerable to this impact.
A new study found stark differences in dementia care received by people in richer and poorer neighborhoods in Quebec. People in more deprived areas were more likely to be hospitalized, receive inappropriate medications, and die within a year of diagnosis, while those in wealthier neighborhoods had more visits to cognition specialists.
Researchers found that Salmonella bacteria target iron-rich regions within immune cells to survive and spread. The pathogens exploit these niches, where the remaining iron is still enough for them to grow, driving infection.
A new study from Boston University Institute for Global Sustainability finds that over 60% of energy infrastructure projects worldwide run over budget and take longer than expected to complete. Nuclear power plants are the worst offenders, with an average construction cost overrun of 102.5%. In contrast, solar energy and wind farms hav...
A new study led by researchers at Mass General Brigham found that more than half of sleep sessions end in a snooze alarm, with users spending an average of 11 minutes on the device. Snooze usage varied by day of the week and was lower among those sleeping five or fewer hours.
Researchers at the Francis Crick Institute found that mice recognize and compare their own social rank to an unfamiliar opponent's using chemical cues. The study showed that both olfactory and vomeronasal systems are used to process this information, allowing mice to compensate if one system is missing.
A new study found that ciliary dynamics play a significant role in the pathophysiology of bronchopulmonary dysplasia, with more severe cases showing distinct ciliary beat abnormalities. The study provides new insights into BPD mechanisms and potential therapeutic targets.
A new protein target has been identified for treating childhood medulloblastomas. High levels of dihydrolipoyl transacetylase make Group-3 medulloblastomas vulnerable to cuproptosis, a newly discovered form of copper-dependent cell death.
Heritage art practices, such as fiber arts and traditional painting styles, have been shown to improve mood and reduce anxiety. The study collected data from participants in the US, Japan, and India, who engaged in activities like creating temporary body art or mizuhiki, tying decorative knots with thin paper strings.
Researchers developed nano-precipitation-strengthened high-entropy alloys, achieving ultrahigh gigapascals yield strength and superb resistance to adiabatic shear failure. Nanoprecipitates act as dislocation barriers and energy-absorbing islands, dispersing strain energy through order-to-disorder transition.
A recent multi-center randomized controlled trial found that testosterone gel does not improve physical function compared to exercise alone in older women recovering from a hip fracture. The study, STEP-HI, is the largest such study of testosterone administration to women following a fracture of the hip.
Experts recommend stopping pacifier use and thumb-sucking before two years old due to potential dental health and speech development impacts. Parents report various strategies to break the habits, including hiding the pacifier, limiting use, or using deterrents like hot sauce.
Janus kinase inhibitors (JAKs) suppress an important immune signalling pathway that helps protect healthy cells from viral attacks. This allows viruses to more easily gain a foothold and spread.
A study by DGIST researchers found that brain inflammation leads to overactivity in NMDA glutamate receptors, causing repetitive behaviors in autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD). Administering memantine, a treatment for Alzheimer's disease, reduced symptoms and restored normal activity.
A recent study published in PLOS ONE found that higher maternal selenium levels during pregnancy are associated with a lower risk of streptococcal infections in children. The research tracked over 74,000 mothers and their children to explore potential links between maternal metal exposure and infection risk.
New research found that inhaled microplastics inhibit tissue maintenance functions of pulmonary macrophages. The findings suggest that exposure to microplastics can lead to long-term disruption of immune function and increase risk of cancer and other diseases.
Researchers analyzed data from the Women's Health Initiative, a large cohort study, and found that using metformin increases the likelihood of reaching age 90 or older. The use of metformin was associated with a 30% lower risk of death before age 90 compared to sulfonylurea.
A recent study found that C5aR1 inhibition can slow endometriosis progression by altering the behavior of immune cells. Researchers used PMX-53 to block the C5aR1 receptor, reducing macrophages with an M2 phenotype and promoting an M1 state.
The new AI chip uses hyperdimensional computing to recognize patterns without requiring millions of data records. This approach saves energy compared to conventional chips, with the new chip consuming only 24 microjoules for training a sample task.
The National Center to Reframe Aging teams up with the California Department of Aging to challenge negative attitudes about aging and promote age-friendly services. The collaboration aims to shift the narrative on aging communication, highlighting the contributions of older adults in California.
A new partnership between Murdoch Children's Research Institute and Retro Biosciences aims to develop personalized blood stem cell treatments for children and adults with blood disorders. The collaboration has the potential to prevent complications from mismatched donors by using a patient's own perfectly matched cells in transplants.
A study published in JAMA Health Forum found that patients with female primary care physicians had better diabetes control, more eye exams, and fewer emergency department visits. Women PCPs also earned more than their male colleagues through value-based payment, possibly due to their patients having lower healthcare utilization.
A new molecular process discovered by researchers contributes to the failure of donor hearts after transplant, but a therapy using medication for high blood pressure has been found to reduce damage. The treatment significantly improves the function of donor hearts and increases their distance in cold storage.
The University of Science and Technology of China has joined Bentham Science's institutional membership program, enabling researchers to publish Open Access articles at concessionary rates. This partnership promotes open research and fosters scientific advancements in science, medicine, and technology.
Research reveals mountain glaciers worldwide will not recover for centuries under 'overshoot' scenarios, where the planet exceeds the 1.5°C limit before cooling back down. Glaciers could lose up to 16% of their mass, leading to increased sea-level rise and disrupting downstream communities.
A promising new anticancer medicine could be made from a mixture of potentially dangerous isomers, which have the same elemental make-up but different structures. This challenges over 60 years of established scientific wisdom and literature, posing major concerns about its use in human subjects.
A study by Trinity Consultants identifies effective means of controlling data center noise, including sound barriers and low-frequency resonators. The goal is to create a quieter breed of data centers that can coexist with residential areas, protecting residents from excessive noise.
Researchers have developed a novel metal-free catalytic approach for upcycling polyethylene terephthalate (PET) waste into valuable products like dimethyl terephthalate (DMT) and ethylene carbonate (EC). The method achieves impressive yields under mild conditions, showcasing its potential for large-scale industrial implementation.
A study published in the Journal of Clinical and Translational Hepatology found that oleanolic acid can restore drug sensitivity to sorafenib in sorafenib-resistant hepatocellular carcinoma cells. The compound inhibited cell invasion, migration, and upregulated fabp3 expression, leading to restored sensitivity to sorafenib.
A new photonic accelerator based on a nonlinear optoelectronic oscillator (NOEO) has been proposed to speed up reinforcement learning in AI. The accelerator outperformed existing methods, achieving high speeds and accuracy in solving complex problems like the multi-armed bandit problem and Tic Tac Toe game.
A new international study published in Nature Ecology & Evolution found that fertilizer can help plants survive short-term periods of extreme drought. The researchers added nitrogen, phosphorus, and potassium to 26 sites across 9 countries and found a 24% increase in plant growth with fertilizer addition.
The Florida Inventors Hall of Fame is proud to announce its 2025 inductees, including pioneers who have advanced fields such as nanotechnology and regenerative medicine. These individuals hold over 460 U.S. patents and embody the spirit of American ingenuity.
Tianjin University has joined the Bentham Science Institutional Membership Program to publish research as Open Access under CC-BY 4.0 license at discounted rates. This partnership aims to foster high-quality research and expand global access to scholarly knowledge.
A large cohort study found that early antibiotic treatment did not significantly improve outcomes for patients with nonsevere COVID-19. The results argue against routine antibiotic use in this population due to associated risks.
Computer scientist An Wang receives a $1M NSF CAREER grant to leverage cloud computing resources for efficient machine learning model training. Environmental engineer Bridget Hegarty receives a grant to develop safe and effective biocontrol for water systems using bacteriophages.
The 'Isle of Fire' video series, developed by Time for Geography, provides a 50-year perspective on the 1973 Heimaey eruption and its impact on volcanic hazard management. The series features cutting-edge techniques in eruption reconstruction and forecasting, as well as modern management strategies.