Articles tagged with Bacterial Pathogens
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Researchers at Johns Hopkins have developed a universal screening approach for vaginal microbiota transplantation (VMT) donors to ensure only beneficial microbes are transferred. The pilot study found that 35% of participants might be eligible VMT donors, and the success rate may depend on a small number of willing 'super donors'.
A study found that premature babies' gut microbiomes remain disrupted after antibiotic treatment, leading to an increased risk of disease and health problems later in life. The research suggests that minimizing antibiotic use in preemies may help prevent these issues.
Researchers found high levels of bacterial DNA and opportunistic pathogens in source water from remote bores in Northern Australia. The study suggests that managing groundwater quality is crucial for ensuring safe drinking water supplies in these communities.
Researchers discovered a potential new treatment for preventing sepsis in burn patients by using the secretions of probiotic bacteria Lactobacillus gasseri to combat antibiotic-resistant Pseudomonas aeruginosa. The study found that applying these secretions to the wound inhibited bacterial growth and prevented biofilm development.
Researchers found that Helicobacter pylori is attracted to bleach, relying on a protein called TlpD to navigate to sites of inflammation in the stomach. This attraction enables the bacterium to turn the body's defenses against it and colonize inflamed tissue.
A research group at University of Würzburg is focusing on the role of bacteria in bee health, finding that environmental factors have a stronger influence on solitary bees than previously thought. The study highlights the need for further research to combat bee mortality.
Researchers at Arizona State University describe an innovative diagnostic technique that pinpoints molecular signatures of Lyme disease with high accuracy. The method, using a multi-platform approach, uncovers six potential biomarkers for early identification of the disease.
A pioneer study published in PNAS reveals that bacterial sex plays a pivotal role in the evolution of the mammalian microbiome. Horizontal gene transfer, facilitated by temperate bacteriophages, is the primary mechanism driving bacterial evolution in a healthy gut.
Researchers at Penn State found that harmless bacteria form biofilms that shelter Listeria monocytogenes in apple-packing facilities. This discovery may lead to alternative strategies for controlling foodborne pathogens.
A new study suggests that Pseudomonas aeruginosa thrives in cystic fibrosis lungs due to an abundance of succinate, a byproduct of cellular metabolism. This excess succinate fuels the growth of the bacteria and promotes chronic infections.
Researchers discovered that EspG protein prevents E. coli from forming pedestals in intestinal cells, allowing the bacteria to anchor and grow. This finding offers new possibilities for treating diarrheal diseases caused by pathogenic strains of E. coli.
Researchers at Stanford University have discovered a potential treatment for citrus greening, a devastating disease affecting the US citrus industry. By studying a symbiotic bacterium, they found 130 compounds that can inhibit the spread of the disease without harming beneficial bacteria.
A team of scientists has developed a locally growing algae species that can be used to extract cellulose nanofibers, forming paper sheets with tailored pore size for effective virus and bacteria removal. The filter has demonstrated excellent efficiency in lab and real-life tests.
Researchers reveal E. coli's ability to detect low oxygen levels in the large intestine, allowing it to establish infection and produce harmful toxins. The discovery could lead to prevention strategies by blocking oxygen sensing, potentially limiting infection and avoiding drug resistance.
Researchers have identified three genes from a probiotic Lactobacillus species as critical for mediating adhesion to the vaginal epithelium. This is likely crucial for how this species benefits vaginal health.
Researchers investigate the microbiome of Stentor coeruleus and find a distinct bacterial community associated with the ciliate. The study reveals that different ciliates can host unique bacterial populations, highlighting the importance of further research into protistan microbiomes.
A WVU researcher is working to preserve pertussis vaccines' effectiveness by exploring ways to improve their recognition of emerging bacterial strains. By incorporating iron-acquisition proteins into the vaccine, Barbier hopes to boost its protection.
A three-site study in the Blue Marsh watershed found seasonal differences in microbial populations, with increases in warmer months and higher levels of nitrate and phosphate. The researchers used Biolog Ecoplates to test water samples, revealing changes in bacterial counts and chemical profiles linked to human activities.
Researchers discovered a connection between high-fat diets and insulin resistance through gut bacteria, specifically the protein IgA produced by B cells in the gut. A high fat diet weakens the gut immune system, leading to inflammation and worsening blood sugar levels.
Researchers at Monash University have discovered an antibiotic that can prevent the life-threatening diarrhea caused by C. difficile. The treatment strategy could also counter diseases caused by other similar bacteria, including anthrax. Studies show that cephamycins can reduce spore production of C. difficile and Bacillus cereus.
Researchers discovered that Clostridium difficile is evolving into two separate species, with one group highly adapted to spread in hospitals. The emerging species, named Clade A, has evolved genes that metabolize simple sugars, allowing it to thrive on Western sugar-rich diets and evade common hospital disinfectants.
New research from Dartmouth College uncovers how cholera bacteria change shape to aid short-term survival in nutrient-poor environments. This strategy supports the growth of bacterial communities and allows pathogens to compete effectively.
A team of scientists analyzed microbial communities within sclerotia of soilborne fungal pathogens, discovering specific bacterial communities that produce volatile compounds with the potential to reduce pathogen viability. Combining different beneficial microorganisms can effectively counteract pathogens.
Researchers found that blood coagulation factors VII, IX, and X can hydrolyze lipopolysaccharides on the bacterial cell envelope, effectively killing Gram-negative bacteria. These proteins may offer new strategies for combating multi-drug resistant superbugs.
A study by Georgia State University researchers found that blocking the bacterial pathogen's ability to uptake zinc can prevent gonorrhea infection. The study provides insight into how to block growth of this pathogen and could move gonorrhea vaccine development forward.
Researchers developed an elastic polymer with broad-spectrum antimicrobial properties, effectively killing viruses and drug-resistant bacteria. The polymer's unique molecular architecture attracts water to kill microbes within five minutes, making it a potential solution for hospital-acquired infections.
Researchers at UT Southwestern Medical Center have discovered that precision editing the gut microbiome can reduce inflammation-associated colorectal cancer in mice. The study suggests targeting metabolic pathways specific to intestinal inflammation could prevent or reduce cancer risk.
Researchers discovered antibiotic properties of a natural product that selectively inhibits pathogen growth while leaving beneficial microbes intact. Synthetic derivatives of this substance have shown enormous antibiotic efficiency against Moraxella catarrhalis and malaria parasites.
Researchers have identified a repurposed compound, bithionol, with selective membrane-targeting properties that effectively kill MRSA persister cells without harming mammalian cell membranes. This breakthrough suggests potential therapeutic applications for bithionol in treating recalcitrant MRSA persister-caused infections.
Researchers have found that hospitals are a significant source of extremely drug-resistant bacteria in Europe, with certain strains spreading rapidly and outcompeting more easily treatable bacteria. The study emphasizes the importance of infection control and genomic surveillance to combat antibiotic resistance.
A new study by University of Exeter researchers shows that pathogens can evolve to become more virulent without increasing their rate of replication. This suggests that manipulating host immune systems may play a role in generating symptoms necessary for transmission.
A recent grant from the National Institutes of Health will support a study investigating the interaction between gut bacteria and fungi in Crohn's disease. The research aims to identify genetic mechanisms underlying these interactions and develop novel antifungal and probiotic strategies to decrease symptoms.
Researchers at Boyce Thompson Institute discovered that ascaroside compounds from nematodes can protect rice, wheat, corn, and soybeans from numerous pathogens. The compounds helped increase resistance against bacterial, fungal, viral, and oomycete pathogens in major crops.
A new study found that organic apples contain a more diverse range of beneficial bacteria, which could contribute to improved gut health. In contrast, conventional apples were found to have higher levels of pathogenic bacteria, such as Escherichia-Shigella. The researchers also discovered that the bacteria in organic apples were more c...
A recent DNA analysis revealed surprising genetic diversity in a bacterium that targets commercial algae, posing a persistent threat to the biofuels industry. The discovery suggests that treatment for one algae pest might not work for another, complicating large-scale algae cultivation.
Researchers developed an algorithm that analyzes immune cell responses to predict disease onset and progression. The algorithm uses 'first impressions' from early interactions between immune cells and bacteria to identify patterns that can be applied to real-time blood tests.
Researchers found a way to stimulate the waking of persisters, dormant bacterial cells that evade antibiotics and lead to chronic infections. Breaking links in the 'pore' formed by peptides enables these sleeping bacteria to regain energy and infect the host again.
Researchers found high densities of flies in primate social groups, recapturing marked flies up to two weeks later. Flies carried anthrax and Treponema pallidum pertenue bacteria, which cause severe lesions in mangabeys.
Researchers created a mathematical model to calculate temperature suitability for citrus greening transmission, mapping areas at risk of production collapse. The study provides critical information for crop management and surveillance prevention.
A new study by researchers from the University of California, Irvine has shed light on the weaknesses of TcdB, a toxin primarily responsible for devastating Clostridium difficile infection (CDI). The study provides a blueprint for the development of next-generation vaccines and therapeutics with enhanced potency and broad-reactivity.
Scientists deciphered how YopO changes its shape to confuse the immune system, disrupting communication and allowing bacteria to evade digestion. Understanding this process may lead to developing targeted, tailor-made substances to inhibit plague pathogens.
A study by ISGlobal reveals that Acinetobacter bacteria commonly acquired in hospitals can also be transmitted through contaminated food, specifically raw meat. The research analyzed 138 meat samples and identified 12 isolates of the ACB complex, suggesting that raw meat may serve as a reservoir for these pathogenic bacteria.
The study reveals that the equilibrium between nose microbes and host has an impact on pneumococcal acquisition density, particularly with viral co-infection. Different microbiota constellations are associated with varying levels of inflammation, viral replication, and pneumococcal carriage receptiveness.
Researchers developed a new technique to enhance the infection-fighting potential of natural chemicals and test them quickly. Three synthetic molecules were found to be four times more effective at killing bacteria than their natural predecessor.
Researchers at CRID found that infants produce 40% more NETs than adults, leading to more severe organ damage and higher mortality rates in sepsis cases. Breaking down NETs with a drug can improve survival rates for infant patients, highlighting new treatment strategies.
A new ultrasensitive chemiluminescence-based method has been developed to rapidly detect Salmonella and Listeria monocytogenes. This test can be carried out in the field and requires no containment laboratory, significantly faster than conventional methods.
Researchers discovered Cas9's ability to block gene activity without cutting DNA in pathogenic bacterium Francisella novicida, regulating disease-causing genes. This finding expands the versatility of CRISPR/Cas9 for genome engineering and potential antibiotic resistance solutions.
Researchers found MRSA acquired mainly through community transmission, with higher prevalence among individuals of immigrant background in Norway. The study suggests a need for coordinated initiatives to reduce the spread of antibiotic-resistant pathogens.
Researchers developed a new technique to visualise the distribution of TB drugs in human macrophages at high resolution. The study found that bedaquiline accumulates in lipid droplets inside host cells, forming a reservoir that supplies the drug to Mtb over time.
Researchers developed a cancer vaccine technology using live, attenuated pathogens as vectors. The novel vaccine causes the bacteria to self-destruct once they've done their job, making it safe for human use. This innovation has potential applications in treating various cancers and infectious diseases.
Research found that 40% of university students' cell phones carried S. aureus, a common cause of hospital and community infections, with 85% resistant to penicillin. The bacteria's presence in healthcare environments could increase infection rates.
Researchers found that extracellular pathogens like Pseudomonas aeruginosa can enter host cells and induce cell lysis through the type III secretion system. The study reveals a new mechanism of bacterial killing in macrophages.
Researchers found 87 genes in E. coli bacteria that protect against plasma treatment, including a heat shock protein Hsp33. The study suggests that genetic changes can increase plasma resistance in bacteria.
Scientists at Cornell University have discovered an unexpected mechanism of activation and inactivation of RNR, a crucial enzyme for DNA replication. This finding provides a potential means to shut off harmful bacteria by understanding the
Researchers have identified a new family of bacteria, Deianiraeaceae, which belongs to the order Rickettsiales and exhibits a unique extracellular lifestyle as a predator. This discovery reveals a significant departure from previously known intracellular parasites.
Researchers have developed a mutant version of the RhlR quorum-sensing receptor, which does not require an autoinducer to function. This discovery provides new insights into cell-cell communication and virulence in Pseudomonas aeruginosa, a globally important pathogen.
Researchers found that the LUX gene regulates stomata opening and closing, as well as activating defense mechanisms. The study could lead to more resistant crops and better treatment for human diseases.
Researchers discovered a grappling hook-like appendage called type IV pili that enables Vibrio cholerae to take up DNA, bind to nutrient-rich surfaces and recognize 'family' members. The findings reveal a multifunctional toolkit for the bacterium's survival in ocean environments.
Princeton researchers found that learned avoidance behavior in C. elegans can be inherited for multiple generations through the germline, with the behavior remaining elevated for up to four generations before returning to normal levels. This study provides new insights into transgenerational epigenetic inheritance and its potential rol...
Researchers discovered a new class of antibiotics produced by the microbiome that kill bacteria by disrupting their energy metabolism. Fibupeptides, such as lugdunin, have shown promise in treating multidrug-resistant infections, including those caused by MRSA.