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Scientists show how fast-growing bacteria can resist antibiotics

A study published in eLife has shown that fast-growing bacteria can resist antibiotics by displaying higher ribosome expression, allowing them to avoid macrolide accumulation. This finding highlights a new survival strategy for bacteria and offers potential avenues for developing improved antibiotic compounds.

SourceeLife·JournaleLife·DateJun 7, 2022

How diverse microbial communities remain stable

A novel computational method estimates the level of connectivity in bacterial communities, revealing that species diversity is limited by interaction strength. Understanding these stability principles is essential for developing medical treatments and preserving the environment.

SourceBar-Ilan University·JournalNature Ecology & Evolution·DateMay 31, 2022

Drug resistance molecule can spread though bacterial 'communities'

A new study by the University of Exeter found that antibiotic-resistant plasmid molecules can spread quickly through bacterial communities, making them more resistant to antibiotics. This raises concerns about the potential for antimicrobial resistance to spread in environmental settings and impact human health.

SourceUniversity of Exeter·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateMay 26, 2022

E. coli bacteria exploits Crohn’s disease inflammation

Research finds that intestinal inflammation liberates chemicals that nourish E. coli's growth and promote inflammation, highlighting new treatment targets for Crohn's disease. The study identifies key compounds that feed E. coli, such as phospholipids and amino acids, and shows that these compounds can enhance the bacteria's virulence.

SourceCornell University·JournalJCI Insight·DateApr 27, 2022

Meat, MS and the microbiome

A study by UConn Health and Washington University School of Medicine found that eating more meat correlates with worse MS symptoms, altered gut bacteria, and increased immune cells. The research identified key bacteria and metabolites associated with the disease, providing new insights into its causes.

SourceUniversity of Connecticut·JournalEBioMedicine·TypeExperimental study·DateJan 27, 2022

Swirling bacteria mimic Van Gogh’s ‘The Starry Night’

Researchers from Rice University and the University of Wyoming discovered self-organization into circular aggregates in Myxococcus xanthus, a model system for social cooperation. The circular behavior is linked to TraAB protein overexpression, which creates a sticky bond between cells, preventing reversals.

SourceRice University·JournalmSystems·TypeExperimental study·DateDec 13, 2021

First study of its kind to investigate a high priority but little known pathogen found in Irish hospitals: Trinity research

Researchers from Trinity College Dublin investigate the epidemiology and population biology of Enteroccocus faecium, a high-priority pathogen. They found that Irish isolates have evolved independently and are diverse, with a unique genetic transposon element encoding vancomycin resistance.

SourceTrinity College Dublin·JournalJournal of Antimicrobial Chemotherapy·TypeExperimental study·DateNov 29, 2021

Warning over antibiotic-resistant bacteria

A study by Anglia Ruskin University has identified potentially dangerous Pseudomonas bacteria in 21% of wild bird faeces collected from locations near the River Cam. The bacteria, which can be passed on to humans through cross-contamination, were resistant to multiple antibiotics.

SourceAnglia Ruskin University·JournalEcology and Evolution·DateNov 17, 2021

A way in: Newly-identified state in bacteria has major implications for antibiotic treatment and resistant strains

Researchers at Hebrew University of Jerusalem discover a 'disrupted' state in bacteria that resists current antibiotics, requiring new pharmacological agents to combat. The breakthrough model predicts bacterial population responses to treatments, offering avenues for better treatments against cancer cells.

SourceThe Hebrew University of Jerusalem·JournalNature·TypeExperimental study·DateNov 17, 2021

Microbial study reveals extended lifespan of starved bacteria

A study led by Jay T. Lennon found that nearly all bacterial populations persisted for 1,000 days without external food, with some having lifespans exceeding 100,000 years. This suggests that microbes can survive long periods of energy limitation and evolve under such conditions.

SourceIndiana University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateAug 13, 2021

Like matryoshka dolls: One insect species introduced decades ago to a small island had an effect on several insect populations

A single butterfly species introduced to an island in the 1990s had a significant impact on several insect populations, leading to genetic decline and high extinction risk for some species. The parasitoid wasp's mobility and symbiotic bacterial relationships played key roles in shaping this outcome.

SourceUniversity of Helsinki·JournalMolecular Ecology·DateAug 2, 2021

Persistence pays off in the human gut microbiome

Researchers investigated bacterial persistence in the human gut microbiome, identifying three dispersal strategies and finding that most strains are highly persistent. The study's results will inform targeted probiotic and treatment approaches to maintain a healthy gut microbiome.

SourceEarlham Institute·JournalCell Host & Microbe·DateJun 14, 2021

Rooting the bacterial tree of life

Researchers have shed light on early bacterial evolution by integrating vertical and horizontal gene transmission, revealing that a tree is still an apt representation of bacterial evolution. On average, genes travel vertically two-thirds of the time, suggesting a tree-like structure.

SourceUniversity of Queensland·JournalScience·DateMay 11, 2021

Citizen science data tracks battle of birds vs bacteria

New research from the Cornell Lab of Ornithology analyzes the impact of a bird eye disease on house finch populations, revealing an escalating arms race between the birds' immune systems and bacterial strains. The study suggests that imperfect immunity is driving this battle, with bacteria evolving to overcome strengthened finch defenses.

SourceCornell University·JournalJournal of Animal Ecology·DateApr 23, 2021

To combat gum disease, help oral bacteria evolve

A study published in International Journal of Environmental Research and Public Health found that exercise can alter the oral environment, favoring less harmful bacteria in people with NAFLD and gum disease. This shift may help reduce inflammation and improve overall health outcomes.

SourceUniversity of Tsukuba·JournalInternational Journal of Environmental Research and Public Health·DateApr 12, 2021

Cellular Chinese whispers

Research on E. coli bacteria reveals that higher translation error rates lead to increased phenotypic variability at the single-cell level, affecting cell length and division time. However, population-level growth parameters show inconsistent correlations with mistranslation levels, highlighting the need for further investigation.

Breakthrough in understanding 'tummy bug' bacteria

Researchers at the University of Exeter have identified a population of dormant Vibrio parahaemolyticus bacteria that are better equipped to revive when conditions improve. The study also discovered an enzyme involved in this process, which breaks down lactic acid into pyruvate, allowing the bacteria to survive for extended periods.

SourceUniversity of Exeter·JournalPLOS Pathogens·DateJan 20, 2021

Buffalo fly faces Dengue nemesis

Researchers are exploring three approaches using the Wolbachia bacterium to control the buffalo fly population and prevent its spread southwards. The methods include artificially infecting adult flies or pupae, releasing sterile males into overwintering areas, and blocking transmission of nematodes closely related to Stephanofilaria.

SourceUniversity of Queensland·JournalParasites & Vectors·DateNov 3, 2020

Gut ecology

A team of UC Santa Barbara researchers proposes a technique called SPARC to manipulate certain parameters in a mathematical gut microbiome model toward a target composition. This approach offers a systematic understanding of how environmental factors and species interactions can be controlled to achieve a stable gut microbiome.

SourceUniversity of California - Santa Barbara·JournalPhysical Review E·DateMay 13, 2020

Microcensus in bacteria

Researchers discovered that bacteria, specifically Bacillus subtilis, can sense the ratios of different bacterial groups in their environment. This ability allows them to adjust their behavior and make informed decisions about their surroundings.

SourceMax-Planck-Gesellschaft·JournalNature Communications·DateMar 5, 2020

Male-killing bacteria linked to butterfly color changes

A recent study found that a bacterium specifically kills male African monarch butterflies, leading to highly variable warning patterns. The researchers discovered that the bacterium's interaction with the female butterflies' unique chromosome arrangement causes this variability.

SourcePLOS·JournalPLOS Biology·DateFeb 28, 2020