Researchers have discovered increased bacterial populations and specific bacteria differences in Alzheimer's brains compared to healthy brains. The findings suggest that bacterial infection and inflammation could play a role in the disease.
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Scientists have found that random diversification and extinction of cells can organize bacteria into taxonomic units as effectively as traditional ecological forces. This discovery challenges current models of microbial classification, highlighting the need for a reevaluation of the task.
A new rational drug design technique identifies molecules targeting multiple receptor sites on key cellular proteins, making it challenging for microbes to develop resistance. The technique has been validated and shows potential in battling drug resistance and even cancer cells.
Researchers found that mosquitoes infected with Wolbachia spread at about 100-200 meters per year in large release sites but had limited impact in smaller areas after two years. This suggests strategic releases can transform urban mosquito populations and virus transmission in cities.
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A new study by San Diego State University suggests that lysogeny, where viruses lie dormant within host cells, may be more prevalent under stressful environmental conditions. This finding has significant implications for understanding degraded coral reef ecosystems and preserving them.
Researchers found that banknotes harbor a diverse range of bacteria, including pathogens like E. coli and Vibrio cholera. The banknotes also contain higher amounts of antibiotic-resistance genes than other environmental samples, highlighting the potential for currency to pose a health risk.
A team of researchers has discovered a new type of living material composed of liquid crystals and bacteria. The combination creates unusual optical, physical, and electrical properties, and the bacteria exhibit collective behavior when at high concentrations. Experiments show that oxygen removal stops the action of the living material.
A team of biophysicists used experiment and mathematical theory to study the changing composition of a mixed bacterial population. They found that in some cases, a strain with a toxin can outcompete another strain, but this depends on various factors such as the environment and initial inoculum size. The results suggest a complex inter...
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A study published in Science reveals how bacteria can exhibit different behaviors despite having the same genes. Researchers found that protein complexes play a crucial role in this phenomenon, and biased partitioning of these complexes can lead to the emergence of extreme phenotypes.
Researchers identified a compensatory mechanism in bacteria that can be used as a new therapeutic target against multi-drug resistant bacteria. The study found that the pace of adaptation in multi-drug resistant Escherichia coli strains is faster than for strains with single resistance mutations.
Researchers found that bacteria in two separate populations can synchronize their oscillations to coordinate nutrient sharing, promoting growth. This communication strategy is similar to engineered systems and allows each community to take turns consuming limited resources, leading to a faster average growth rate.
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A new study found that chance encounters contribute to variations in human gut microbiome populations, which can influence health and disease outcomes. The researchers used genetically identical worms to model the gut's microbe communities, showing that initial colonization events can lead to dominant populations of bacteria.
Researchers at Yale University and Vanderbilt University have discovered a common bacterium that can be used to sterilize male insects, potentially controlling disease-bearing mosquitoes and agricultural pests. The discovery of two genes encoded by Wolbachia bacteria can completely sterilize male fruit flies.
Researcher Nathan Schmidt aims to determine which gut microbes protect against malaria and how they interact with the parasite. His study builds on previous findings showing that mice with certain gut microbiota are less susceptible to severe malaria infection.
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Researchers found that bacteria can quickly adapt to antibiotic treatments by evolving dormancy mechanisms. Once tolerant, they rapidly acquire resistance mutations, making it difficult for antibiotics to kill them. This discovery has important implications for the development of new antibiotics.
Research reveals that bacteria eliminating competitors creates conditions for thriving populations, leading to cooperative family structures. The study suggests that similar patterns can be seen in natural objects, providing insights into bacterial behavior.
Researchers studying NASA astronaut Scott Kelly's gut bacteria found changes associated with spaceflight that reversed upon return to Earth. The study, part of the 'twins' research, also discovered fluctuations in bacterial populations between identical twin brothers Scott and Mark Kelly.
Commonly prescribed acid suppression medications were linked with increased risks of intestinal infections with C. difficile and Campylobacter bacteria. Users should be vigilant about food hygiene due to the removal of stomach acid making them more susceptible to infection.
Researchers discovered that bacteria can gauge population density through quorum sensing and boost their CRISPR-Cas immune systems in response, providing new insight into bacterial collective immunity. This ability enables bacteria to preemptively elevate their immunity when most at risk of a virus spreading.
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Scientists at Oregon State University have discovered a bacterium that can help control a plant-parasitic roundworm, potentially providing an environmentally friendly alternative to traditional pesticides. The worm, Pratylenchus penetrans, uses more than 150 species as hosts, and the newly discovered bacterium is a strain of Wolbachia.
Researchers found that bacteria that become dependent on their environment for essential nutrients outperform those that can produce them independently. The study's results suggest that this loss of autonomy may be an evolutionary advantage driving adaptation in bacterial populations.
A study found that cranberry capsules did not significantly reduce the presence of bacteriuria and pyuria, or the number of urinary tract infections, among older women living in nursing homes. The results contradict previous studies suggesting cranberry products may be effective in preventing UTIs.
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Nair's work aims to treat inborn errors of metabolism using naturally occurring safe gut bacteria. He seeks new treatment options for congenital orphan diseases caused by improper food metabolism.
A new study found that ICU patients experience a rapid depletion of health-promoting microbes and an increase in pathogenic strains, leading to worsening dysbiosis. Researchers tracked changes in bacterial makeup over time and compared data to healthy individuals, revealing the critical impact of ICU stays on gut microbiomes.
A NSF-funded mathematician is working on a model to track how to fight A. aegypti mosquitoes carrying the Zika virus using Wolbachia-infected mosquitoes, reducing their lifespan by a day or two. The goal is to create an endemic population that can displace the virus-carrying population in the wild.
Researchers at UC San Diego and MIT developed a synthetic biology strategy to produce cancer drugs in mice while limiting bacterial population growth. The approach enables controlled release of drugs at tumor sites, reducing tumor size by combining chemotherapy with gene products produced by bacteria.
Researchers discovered that bacteria divide asymmetrically when exposed to stress, accumulating defects in some individuals while others remain young and healthy. This collective behavior allows the bacterial colony to stay young, produce more offspring, and maintain overall health.
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Researchers found that strains of E. coli resistant to one antibiotic can protect other bacteria growing nearby, demonstrating a type of mutualism known as cross-protection. This phenomenon allows bacteria to form drug-resistant communities and survive in environments containing both antibiotics.
A recent study reveals that bacteria can differ significantly in their response to a lack of nutrients, allowing the group to continue growing even when some cells suffer. This phenomenon promotes flexibility and diversity within bacterial populations.
A new study links gut bacteria to post-menopausal bone loss, showing probiotics can prevent this condition by attenuating inflammation. Treatment with probiotics also reduced bone loss in normal mice, highlighting therapeutic potential for probiotics in osteoporosis prevention.
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Research by University of Exeter academics reveals that genetic diversity in bacterial populations can help control the spread of diseases. By generating a diverse CRISPR-Cas immune system, host diversity limits parasite evolution, leading to rapid extinction of viruses on mixed-population hosts.
Researchers discovered that synonymous mutations in genes can significantly impact an organism's fitness and survival. In a study on the bacterium Methylobacterium extorquens, scientists found that highly beneficial synonymous mutations enabled bacteria to quickly evolve and adapt to their environment under strong selection conditions.
Researchers have found a significant association between certain oral bacteria and the risk of hemorrhagic stroke. The study suggests that oral health is important for brain health and may play a role in the development of other diseases such as dementia and rheumatoid arthritis.
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Researchers discovered that gut microbiomes play a role in reducing the severity of malaria. Mice fed yogurt with specific bacteria showed decreased malaria pathology. The study provides a potential new approach to developing treatments for malaria.
Bacterial restriction-modification systems can overreact, leading to autoimmunity issues, according to a new study published in Current Biology. The researchers discovered that more efficient systems are prone to making mistakes, which can contribute to genetic variation and adaptive evolution.
A study found that low-fiber diets can lead to a decline in gut bacterial diversity, which cannot be fully recovered even after switching to a high-fiber diet. This effect is observed even across multiple generations, with nearly three-quarters of bacterial species becoming extinct within four generations.
Researchers found that if groups of targeted cells are large enough, the bacterial superweapon T6S can be thwarted. This allows protected interior cells to multiply quickly and replenish the group's numbers, making it impossible for the bacteria to take over. The study provides insight into how cells withstand powerful aggressors.
Researchers discovered a unique antibiotic molecule that triggers a bacteria's adaptation strategy, enabling it to resist the drug. The resistant bacteria undergoes morphological changes and can move away from the antibiotic, allowing it to survive and spread.
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Researchers at Washington State University have developed an antibiotic-free alternative to treat bacterial infections, using electrical stimulation that kills 99.99 percent of bacteria in 24 hours. The method involves passing an electric current over a film of bacteria, producing hydrogen peroxide as an effective disinfectant.
People fed β-glucan-enriched pasta for two months showed increased populations of beneficial Lactobacilli and reduced LDL cholesterol. The study also found an increase in certain short-chain fatty acids with anti-inflammatory activity.
A new study found that viruses flourish in the guts of healthy infants, with diverse viral strains and a dynamic ecosystem of interacting organisms. The researchers discovered viral strains that exclusively kill bacteria, which declines as the babies grow older.
Researchers at Joslin Diabetes Center found that certain gut bacteria strains are associated with insulin resistance and metabolic syndrome in mice models. The team identified three common mouse strains with different microbiota populations, which were affected by diet and genetic background.
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Rice University scientists have created a multicellular bacterial circuit that allows bacteria to cooperate and control protein expression. This breakthrough enables the development of biological computers that can be programmed through diet, with potential applications in treating diseases and manipulating the gut microbiome.
Researchers discovered that multidrug-resistant Acinetobacter baumannii can voluntarily relinquish its antibiotic-resistance genes, making it susceptible to existing antibiotics. This finding provides new strategies for combating the growing problem of antibiotic resistance.
A high-fat diet changes the populations of bacteria residing in the gut, altering signaling to the brain and leading to overeating. The study found that this shift can cause inflammation in brain regions responsible for feeding behavior, resulting in gut-brain miscommunication and obesity.
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The research team created a single-molecule, real-time sequencing method to detect and phase DNA methylation in bacteria. They found that individual bacterial populations have distinct subpopulations with different gene expression patterns, which may contribute to increasing antibiotic resistance.
Researchers found that Agion silver zeolite technology significantly reduced bacterial populations on door handles, particularly gram-negative bacteria. The study suggests that the technology may be more effective than previously thought, but further research is needed to address concerns about standardization and potential side effects.
Researchers found that hot spring bacteria exchange genetic material through quasi-sexual gene transfer, driving genetic diversity and creating new combinations of genes. This process is driven by frequent swapping of DNA between organisms, allowing for rapid spread of gene variations.
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Researchers discovered that myxobacteria cells can use social behavior to repair damaged siblings by exchanging outer membrane content. This cooperative behavior improves the fitness of the entire bacterial population.
A new study found a sequential pattern of changes in the intestinal microbial population of patients recovering from cholera, suggesting potential strategies to support recovery. The gut microbiota usually returns to normal after cholera infection.
A team of researchers found that limiting migrations among populations of bacteria produced better adaptations and allowed for a wider variety of peaks, enabling the organisms to adapt to their environment more effectively. This 'tortoise-hare' pattern highlights the importance of slow and steady evolution in achieving long-term success.
A new rapid method for typing Clostridium difficile bacteria developed by the Public Health Agency of Sweden allows laboratories to quickly establish the presence of hospital outbreaks. This enables early detection and action, reducing the risk of transmission between patients.
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Researchers identify a time window when moderately resistant bacteria are sensitive to antibiotics, allowing for optimal treatment design. A new approach may help reintroduce antibiotics that were previously disregarded due to treatment failure concerns.
Researchers found nearly double bacterial diversity among Yanomami Amerindians compared to industrialized countries, and higher than other remote populations exposed to modern practices. The study suggests a link between antibiotic usage, western diet, and reduced bacterial diversity.
Scientists have isolated bacteria that inhibit the growth of the white-nose syndrome fungus in laboratory tests. The bacteria may help protect bats from the disease when treated with a bacterial spray applied during hibernation.
A pioneering new technique using sequential treatments may help combat the rise of antibiotic-resistant bacteria by killing them at lower doses than usual. This approach reduces the risk of bacteria becoming resistant to antibiotics, maintaining long-term effectiveness.
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Scientists deciphered bacterial communication mechanisms, revealing new ways bacteria regulate gene expression. Quorum sensing controls a variety of biologically relevant processes, and the study expands our understanding of regulation in Bacillus subtilis.
A recent study found that sudden growth of Burkholderia multivorans preceded periods of acute illness in a CF patient. The team used an extensive collection of lung sputum samples to analyze the bacterial community, providing critical context for their research.
Researchers from Marine Biological Laboratory and University of Wisconsin-Milwaukee used sewage samples to compare human gut bacteria with high accuracy, revealing a core set of bacteria linked to obesity levels in cities. The approach provides a non-intrusive way to monitor public health without compromising individual privacy.
Researchers investigated how Pseudomonas aeruginosa bacteria swarm in groups containing millions of cells. They found that appendages called 'pili' link together to alter group motion and give swarming groups braking power, helping them avoid toxins.