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Tortoise approach works best -- even for evolution

A team of researchers found that limiting migrations among populations of bacteria produced better adaptations and allowed for a wider variety of peaks, enabling the organisms to adapt to their environment more effectively. This 'tortoise-hare' pattern highlights the importance of slow and steady evolution in achieving long-term success.

SourceMichigan State University·JournalProceedings of the National Academy of Sciences·DateMay 11, 2015

The Achilles' heel of antibiotic-resistant bacteria

Researchers identify a time window when moderately resistant bacteria are sensitive to antibiotics, allowing for optimal treatment design. A new approach may help reintroduce antibiotics that were previously disregarded due to treatment failure concerns.

SourcePLOS·JournalPLOS Computational Biology·DateApr 23, 2015

Sewage provides insight into human microbiome

Researchers from Marine Biological Laboratory and University of Wisconsin-Milwaukee used sewage samples to compare human gut bacteria with high accuracy, revealing a core set of bacteria linked to obesity levels in cities. The approach provides a non-intrusive way to monitor public health without compromising individual privacy.

A gut reaction

Queen's University scientists found that nanosilver can upset the human gut community at low concentrations. The discovery highlights the potential risks of nanoparticles in everyday life and underscores the need for further research on their long-term effects on health.

SourceQueen's University·JournalJournal of Nanomedicine & Nanotechnology·DateNov 19, 2014

Shift in gut bacteria observed in fiber supplement study may offer good news for weight loss

A new study from the University of Illinois shows that two specific functional fibers may assist in weight loss when made part of a long-term diet. The researchers observed a shift in the Bacteroidetes:Firmicutes ratio toward more Bacteroidetes, which has been linked to being leaner, and found modifications in nutrient metabolism.

Reading a biological clock in the dark

A new study published in Cell reveals that our biological clocks work in tandem with the populations of bacteria residing in our intestines. The findings show that mice and humans with disrupted daily wake-sleep patterns exhibit changes in gut bacteria composition and function, increasing their risk for obesity and glucose intolerance.

Engineered bacteria keep mice lean

A study published in the Journal of Clinical Investigation found that engineered bacteria can prevent weight gain in mice by producing a compound called NAPE, which signals the brain to stop eating. Mice fed high-fat food with NAPE-producing bacteria exhibited limited weight gain and associated symptoms.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateJun 24, 2014

White bread helps boost some of the gut's 'good' microbes

A study published in ACS' Journal of Agricultural and Food Chemistry found that white bread promotes the growth of Lactobacillus, a group of beneficial gut bacteria. The researchers also discovered that considering the whole diet, not just individual ingredients, is critical for maintaining a good balance of gut microbes.

SourceAmerican Chemical Society·JournalJournal of Agricultural and Food Chemistry·DateJun 11, 2014

Lifestyle determines gut microbes

Researchers analyzed the gut microbiota of Hadza hunter-gatherers, revealing a unique microbial profile that supports their adaptation to a foraging subsistence pattern. The study found differences in gut microbiota between sexes, reflecting sexual division of labor and having implications for fertility and reproductive success.

SourceMax-Planck-Gesellschaft·JournalNature Communications·DateApr 15, 2014

Eliminating bacteria, changing lifestyle could lower risk in people genetically susceptible to colorectal cancer

A study led by Dr. Sergio A. Lira found that removing gut bacteria reduced polyp formation and inflammation in mice, potentially reducing colorectal cancer risk. The researchers propose a new approach to understanding the interplay between genetic mutations, gut bacteria, and inflammation.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalJournal of Experimental Medicine·DateMar 3, 2014

Dispersal patterns key to invasive species' success

Researchers at Duke University tested a theory on bacterial dispersal patterns using E. coli, finding that spreading out to multiple habitats simultaneously can be beneficial but also increases the risk of population collapse due to the Allee effect. This study has implications for managing invasive species and understanding the impact...

SourceDuke University·JournalProceedings of the National Academy of Sciences·DateJan 20, 2014

Innovative approach could ultimately end deadly disease of sleeping sickness

A mathematical modeling study suggests that a new approach could reduce or eliminate the deadly disease African trypanosomiasis, also known as sleeping sickness, by creating a genetically modified version of the Sodalis bacteria to kill the parasite. The approach, which uses Wolbachia bacteria to drive the GMO version into fly populati...

SourceOregon State University·JournalPLOS Neglected Tropical Diseases·DateOct 3, 2013

Study looks beyond averages to track variability in a bacterial population

A recent study by University of Illinois researchers identified behavioral subtypes within a modeled Escherichia coli population based on gene regulation and protein distributions. The findings suggest that tracking specific genes may be sufficient to capture most of the metabolic variability in the entire population.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalProceedings of the National Academy of Sciences·DateJul 29, 2013

Using bacteria to stop malaria

A study at Michigan State University demonstrates that using a strain of the bacteria Wolbachia can interrupt the transmission of malaria via mosquitoes. This approach could provide an important tool in fighting the disease, particularly in areas where poverty and lack of resources are prevalent.

SourceMichigan State University·JournalScience·DateMay 9, 2013

Genome sequencing provides unprecedented insight into causes of pneumococcal disease

A study using genome sequencing technology revealed that pneumococcal bacteria population shifted from targeted vaccine strains to rare, pre-existing types, explaining the vaccine's effectiveness. This breakthrough enables real-time surveillance of bacterial populations, improving understanding of vaccination effectiveness and future d...

SourceHarvard T.H. Chan School of Public Health·JournalNature Genetics·DateMay 5, 2013