Researchers at Scripps Florida aim to block breast cancer growth by targeting a specific microRNA that adapts cancer cells to low oxygen environments. Inhibiting this microRNA increases the sensitivity of cancer cells to death and makes them more vulnerable to chemotherapy.
The symposium highlights opportunities to utilize federal big data initiatives in dental research, such as BD2K, to advance research and practice. Panelists will discuss the potential of linked data for dental providers.
Researchers at MIT and Harvard University have developed a new cryptographic system called Sieve that allows users to store and manage their personal data securely. With Sieve, users can control which apps have access to their data and revoke access with ease.
A meta-analysis of randomised controlled trials suggests that antibiotics can be used as primary treatment for mild appendicitis, reducing surgeries by 92% within the first month. However, recurrence rates remain high at 23% and long-term follow-up is needed to determine effectiveness.
The study highlights the importance of time context in diet reconstructions, which can lead to conflicting results. By considering different time scales for dietary proxies, scientists can gain a more accurate understanding of an animal's eating habits.
A new study by University of Florida researchers found that victorious ant colonies recruit members of losing colonies to help defend their territory. After analyzing DNA from nearly 800 ants, the team discovered that fighting changes the genetic makeup of victorious colonies, allowing them to form lasting truces with former foes.
Researchers find Tanana Arctic butterfly, a possible new species of hybrid butterfly from Alaska's interior. The discovery suggests ancient hybridization between Arctic butterfly species.
The Hong Kong Polytechnic University has developed an intelligent wheelchair system called iWheelchair, integrating various functions such as environment control, safety, and health monitoring. The system allows users to control home devices using a tablet computer, with features like fall monitoring and smart diaper detection.
Researchers at the University of Adelaide have developed a faster and more accurate flood risk assessment method that relies on an algorithm to extract key causative events driving major floods. This new approach reduces the time taken for modeling while maintaining high accuracy, potentially saving properties and lives.
A new study finds that natural resilience may not be as common as thought, and when confronted with a major life-altering event, many people can struggle considerably. The study's findings go against previous claims that resilience is the typical response to major life stressors.
Scientists have developed a novel approach to track neural stem cells using microscopic iron beads and magnetic resonance imaging, allowing for non-invasive tracking without harming the cell. The findings focus mainly on neural stem cells but also show potential for use with mesenchymal stem cells.
Researchers at Brigham and Women's Hospital developed a wearable device to monitor and control organs-on-chips, a platform for testing drug compounds. The system uses Google Glass for hands-free control and monitoring, enabling high-accuracy predictions of physiological responses.
Researchers discovered that synonymous mutations in genes can significantly impact an organism's fitness and survival. In a study on the bacterium Methylobacterium extorquens, scientists found that highly beneficial synonymous mutations enabled bacteria to quickly evolve and adapt to their environment under strong selection conditions.
A study presented at the 2016 USCAP Conference found that HER4 expression is associated with chemotherapy resistance and a lower survival rate in ovarian serous cancer patients. The research, led by Moffitt Cancer Center pathologists, suggests that HER4 may be a prognostic and potentially predictive marker for this type of cancer.
Scientists have identified a new gene, GT198, that causes breast cancer and can be used to diagnose the disease early. The gene is normally regulated by estrogen but becomes mutated when it causes rapid growth of cancer cells.
Research by University of York scientists shows how ketamine causes inflammation and cell death in the bladder, leading to cystitis. The studies found that direct contact with urinary ketamine is critical to the toxicity, ruling out systemic factors.
A new meta-analysis supports the link between Omega-3 supplementation and reduced major depressive disorder (MDD) rates. The study found a comparable benefit to antidepressants in patients taking EPA and DHA supplements.
Researchers developed a novel RNA-based hairpin molecule to inhibit microRNA activity in cells and mice. The plasmid-based microRNA inhibitor system effectively knocks down endogenous miRs, revealing roles for miRs in developmental pathways and cellular processes.
Researchers found significant bacterial contamination in buildings with storage tanks and altered plumbing, which can lead to chlorine resistance. To mitigate this risk, precautions should be taken to prevent bacterial introduction into the system.
Researchers analyzed six years of dental claims data to evaluate the longevity of restorations in primary molars. Sealants showed better survival rates when applied to children under three years old, while one-surface composite had similar longevity to one-surface amalgam.
Researchers have developed a unified mathematical framework to design a single global input that synchronizes nonlinear rhythmic units in nature and manmade systems. This breakthrough enables better understanding and control of oscillation in applications such as heart pacemakers, neuronal firings, and circadian timekeeping.
China's sweeping program to restore forests has seen significant gains in tree cover, with nearly 61,000 square miles of land recovering, while 14,400 square miles experienced loss. The recovery is encouraging, but researchers emphasize the need for further research on the broader impacts of forest degradation and recovery worldwide.
A study found that Canadian First Nations children with severe early childhood caries had a distinct oral microbiome, with higher levels of cariogenic microorganisms and population shifts in their oral microbial communities. This may explain the high prevalence of S-ECC in Indigenous children.
A new computer model has been developed to design safer versions of fast ships used in search and rescue operations. The model produces accurate animations and simulations that can show how sea waves affect these craft, highlighting the importance of accurate predictions of pressure forces.
New research from Penn Medicine shows a concerning trend of increasing opioid prescribing after common surgeries, with most patients filling a prescription for an opioid pain medication within seven days. The study's findings highlight the need for better strategies to treat postoperative pain safely and effectively.
Tropical Cyclone Emeraude intensified rapidly after forming on March 15, 2016, with GPM's radar measuring extreme rainfall rates of over 8.2 inches per hour. The storm peaked at 125 knots and then weakened, but is expected to re-intensify as it curves toward the southwest.
Researchers found that consistent treatment of customers and employees amplifies positive impact on firm valuation, while inconsistency weakens it. Companies with narrow business scopes benefit from coordinated activities, as investors can better judge management of key stakeholders.
A study found that ocean acidification worsens during nighttime hours in tide pools along California's rocky coast. The increasing acidity harms calcifying organisms like mussels and oysters by dissolving their calcium carbonate shells and skeletons.
The International Human Frontier Science Program has selected eight researchers to receive Career Development Awards, worth $300,000 over three years. The award supports the launch of their first independent laboratory and enables fellows to return home or move to another HFSP member country.
A recent study by University of California, San Diego School of Medicine reports that educating Community Health Workers (CHWs) and other 'citizen scientists' can boost the integrity of scientific research. The Building Research Integrity and Capacity (BRIC) program uses eight modules to teach research ethics and concepts.
A new study finds that an education strategy called teach-to-goal can effectively educate patients on using their rescue inhalers properly. The researchers found that this approach improved patient mastery of inhaler technique and reduced the need for hospitalization.
The AADR/ADA symposium aims to bridge the gap between research evidence and clinical decision-making. Participants will learn how to quickly access research evidence, interpret its findings, and apply them to patient care.
Research by Uppsala University and colleagues found that small passerine birds have ultra-rapid vision, with some species able to detect changes at rates of up to 146 Hz, outpacing human vision by 50 Hz. This fast vision is thought to be an evolutionary adaptation for detecting moving insects.
A total of 697 applications were received for 75 HFSP postdoctoral fellowships, with 69 Long-Term Fellowships awarded to life scientists extending their expertise into another field and 6 Cross-Disciplinary Fellowships supporting young scientists from non-life science backgrounds
Researchers at Penn Vet have found that retinal cells continue to differentiate and divide before overwhelming cell death causes degeneration, a common feature of inherited blindness diseases. This study suggests that this feature may be present across many forms of inherited blindness.
A study in western Kenya assesses the acceptability of dihydroartemisinin-piperaquine (DP) as an alternative to sulfadoxine-pyrimethamine (SP) for preventing malaria in pregnancy. The trial found promising results but identified challenges related to adherence and confidence in rapid diagnostic tests.
A team of Korean scientists has developed a new framework for understanding acid-base reactions in organic chemistry. The study revealed that hydrogen-bonded clustering plays a critical role in enhancing the reactivity of alcohols and promoting the formation of an effective Brønsted base.
Researchers found a pathway in the brain linked to forgetting, which erases memories. The study suggests a balance between learning and forgetting is necessary for memory formation.
Researchers from the University of Surrey have discovered a new physical mechanism that separates particles according to their size during the drying of wet coatings. This 'self-layering' process creates two layers with independent properties, which could improve the performance of coatings across industries.
The University of California, Riverside, has received a nearly $1.6 million grant from the National Science Foundation to sequence the genome of the cowpea, a legume crop crucial for global food security. The research aims to develop high-yielding and disease-resistant cowpea varieties using genetically informed breeding strategies.
Researchers found that SIX1 plays a more substantial role in human kidney development than previously thought, remaining present beyond the initial branching of the kidney. This discovery may help better understand normal development and pediatric kidney cancer, Wilms' tumor.
Recent studies by UCLA neuroscientists indicate that our brains may be primed for empathy and altruism, with areas like the amygdala and anterior insula linked to experiencing pain and emotion. Temporarily disrupting prefrontal cortex activity can increase generosity, particularly towards those in need.
Studies presented at the Eighth Annual PPSSC Conference showcased advancements in targeting stem cells, adipose-derived stem cell plasticity, and melanoma immunotherapy using genetically engineered iPSCs. These breakthroughs hold promise for developing effective treatments for regenerative medicine and cancer
A study published at UT Southwestern Medical Center identified over 1,000 gene variants linked to systemic lupus erythematosus (SLE), a serious autoimmune disease. The findings support the potential of precision medicine to improve diagnosis and treatment for SLE, which affects nine times more women than men.
A new study has found that gay and lesbian Canadians experience more mood and anxiety disorders than other Canadians, with bisexual Canadians reporting the highest rates. The research is based on data from over 220,000 Canadians who participated in the Canadian Community Health Survey between 2007 and 2012.
A team of Stanford Bio-X scientists developed the first technique for viewing cells and tissues in 3 dimensions under the skin. The MOZART technique allows for real-time imaging of individual cells or molecules in a living animal, enabling doctors to monitor tumors and understand how cells break free from tumors.
A multi-country study by NYU's Steinhardt School suggests that educational practices may spur innovation, rather than just personality and family history. College experiences, including challenging learning environments and relationships with faculty, positively influence innovative entrepreneurial intentions.
A recent study by researchers at Kyushu Dental University found a significant evidence-practice gap for sealant application among Japanese dentists. The findings suggest that dentists' beliefs about the effectiveness of caries risk assessment are strongly associated with their recommendation of dental sealants.
Researchers found that Cirara, an investigational drug, powerfully reduced brain swelling and death in patients who suffered a type of large stroke called malignant infarction. Six months after the stroke, patients who received Cirara had a three-fold reduction in overall mortality and a ten-fold decrease in death from brain swelling.
Researchers found that women who take the birth control pill are less likely to suffer serious knee injuries compared to those who do not use hormonal contraception. Women between 15-19 years old with ACL injuries were 22% less likely to be taking birth control pills.
Researchers identified eight functional variant mutations in the ADCY9 gene associated with non-syndromic oral clefts (nsCL/P) in Puerto Rican children. The study found three rare missense mutations, including rs52791170/K564Q and rs372048350/A811V, which were not previously reported in Puerto Ricans.