A recent study by Newcastle University has found that finfish populations have declined drastically over the last 65 years due to uncontrolled fishing, with five species now fighting for survival. The research highlights the urgent need for action to protect coral reefs and the ecosystem as a whole.
Researchers created a simplified platform to make macrolide antibiotics without the original molecule, enabling potential solutions to antibiotic resistance. The platform has shown promise in initial testing against clinical bacterial strains and resistant superbugs.
Researchers at the University of Manchester have developed a composite material that combines graphene with natural rubber and polyurethane, resulting in increased strength and elasticity by up to 50%. The added graphene enhances the materials' ability to stretch and withstand force without breaking.
A team of scientists developed a theoretical model explaining the high values of linear magnetoelectric effect in BiFeO3. The effect can enhance materials for industrial applications and control magnetic properties with electric fields.
A Fulbright Scholar will conduct research on women's sexual health literacy in Sierra Leone with a focus on HIV incidence, contraceptive use, and prenatal health. The study aims to enhance understanding of women's health literacy among unmarried women in the region.
Researchers at Rice University have developed a new cancer-imaging technique that uses carbon nanotubes tagged with antibodies to pinpoint the location of tumors. The technique, known as spectral triangulation, uses non-invasive optical measurements to determine the depth and coordinates of the nanotube beacons in tissue.
A study from Northwestern University found that some FDA-approved high-risk medical devices used in obstetrics and gynecology were not effective in clinical trials. The authors recommend increasing the burden of proof required for device approval and relying on higher quality studies.
Microbes produce methane by attaching a methyl radical to coenzyme M, contradicting previous ideas that relied on a nickel-based mechanism. This discovery could lead to breakthroughs in designing energy-efficient catalysts for converting methane into fuels and chemicals.
The report shows that ICSI use is approaching 100% in some regions, despite being developed for male infertility. The editor highlights the need to make decisions based on evidence, warning against unnecessary and costly care.
Researchers developed a dual nanoparticle delivery system for piperlongumine and TRAIL, demonstrating increased therapeutic efficacy in vitro and in vivo. The system sensitizes cancer cells to TRAIL, leading to higher apoptotic rates and improved anti-cancer effects.
Researchers at Imperial College London have discovered a method to predict avulsions in river deltas, which can cause flooding and destruction. The team used experimental flooding conditions to confirm the key factors contributing to avulsion locations.
A new study finds that probiotic bacteria can reduce cadmium absorption in the intestines of mice by mitigating oxidative stress. The research provides evidence that probiotics can inhibit the toxic effects of cadmium on the gut barrier, potentially offering a solution to heavy metal contamination in public health.
The new guidelines provide evidence-based recommendations for the diagnosis and treatment of acute and chronic heart failure, including the use of LCZ696 and adaptive servo-ventilation. The guidelines also introduce a new category for patients with mid-range ejection fractions and provide novel recommendations for preventing and treati...
The University of Waterloo's IQC developed software to assess QKD protocol security, achieving perfect agreement with previous results and enabling exploration of new protocols. The tool enables users to analyze any protocol in seconds, a significant improvement over months-long efforts.
A new tool helps guide resource allocation for Zika virus interventions by analyzing health impact and costs. The tool suggests that proposed funds to combat Zika in the US and other countries would be cost-effective, particularly for measures reducing Zika infections.
Researchers at UMass Chan Medical School are developing a web-based care plan for osteoarthritis patients, utilizing a national database of total joint replacement patients. The care plan aims to improve patient-clinician interaction and informed decision-making, enhancing the quality of care and outcomes.
Researchers propose Spherical Brain Mapping (SBM) to detect Alzheimer's disease, achieving 91% accuracy in differential diagnosis. The framework projects three-dimensional MR brain images onto two-dimensional maps, revealing statistical characteristics of tissue, and can be visually assessed for diagnosis.
A new study combines large datasets to estimate the number of microbial and non-microbial species on Earth, suggesting nearly 1 trillion species exist. The research uses universal scaling laws to predict species numbers, revealing simple yet powerful trends in biodiversity.
Scientists have successfully demonstrated size quantization of charge carriers in graphene nanoconstrictions, revealing key details relevant to future electronic devices. The study utilized high-quality samples and low temperatures to accurately measure the effects, closely following theoretical predictions.
Researchers aim to understand the root causes of coronary microvascular dysfunction, a condition that damages tiny coronary arteries in women. The study will test the hypothesis that impaired relaxation of the heart muscle contributes to progression of heart failure.
A team of researchers has developed an all-on-chip method for testing neutrophil chemotaxis directly from whole blood using a microfluidic system. The method enables rapid and accurate analysis of neutrophil migration in under 25 minutes, overcoming labor-intensive traditional cell preparation methods.
A recent study by the U.S. Department of Energy's Argonne National Laboratory reveals that temporary oilfield workers are a major factor in increased water use in the Bakken region. Water usage has more than quintupled from 2008 to 2012, with most water coming from Lake Sakakawea.
Cardiologists from 115 countries gained knowledge and skills in treating cardiovascular disease through live demonstrations and educational sessions. They learned about the latest developments and best practices in coronary interventions, valvular disease, heart failure, peripheral interventions, and more.
Scientists found that selectively fishing for lingcod in closed areas can help avoid harming other fish species, including rockfish listed as overfished. The approach aims to balance the needs of fishermen with conservation efforts, potentially benefiting both groups.
Researchers identified a specific enzyme and signaling pathway involved in resistance to treatment, which can be targeted by other drugs for improved outcomes. Glioblastoma multiforme tumors were shown to manipulate their surrounding environment to evade therapy, leading to longer survival when treated with combination therapies.
Researchers combine radiation treatments with new immunotherapies to target melanoma, showing synergistic effects that improve treatment outcomes. The combination of radiation and immunotherapy has been shown to increase one-year survival rates for patients with Stage 4 metastatic melanoma.
A new study from the University of Rochester Medical Center suggests that student-athletes who experience concussions often struggle academically, even after returning to school. The research found significant academic problems among students with concussions compared to those with other sports-related injuries.
The US is projected to see a doubling of visual impairment and blindness cases by 2050, with the greatest burden on non-Hispanic white women and African Americans. The National Eye Institute predicts that 2.15 million non-Hispanic white women will be visually impaired by then.
A UCL-led study identifies five genes controlling nose and chin shape, providing new insights into human face evolution and potential forensics applications. The study analyzed over 6,000 individuals with varied ancestry and found specific genes influencing facial features.
Researchers at Mount Sinai Hospital have developed a strategy to create the first broad-spectrum antiviral drug, which could provide protection against seven deadly viruses, including Nipah and Ebola. By targeting a single gene, the approach boosts immunity against viral infections.
The University of Texas at Arlington has established a new Veterans Business Outreach Center to provide educational and training services to veteran entrepreneurs. The center will offer collaborative learning opportunities, one-on-one counseling, and workshops on starting a business, leveraging a $500,000 SBA grant.
A study of 88 teenage boys found that those who experienced sudden growth spurts had lower coordination and more irregular gaits than their peers, suggesting that the brain needs time to adjust to rapid height increases.
A new study using mice and lab-grown human cells shows a triple-drug cocktail can shrink triple-negative breast cancers by killing off cancer cells and halting new tumor growth. The combination treatment, EAD therapy, reduced the size of tumors in mice and decreased tumor growth in spheres grown from patients' metastatic cells.
A targeted screening program in Canada identified a high proportion of individuals with risk factors for chronic kidney disease and many with unrecognized CKD. The See Kidney Disease (SeeKD) program successfully promoted good kidney health and provided early detection of CKD, emphasizing the importance of targeted screening.
A previously undetected mutation in a strain of C57BL/6 mice has been found to affect the results of immune system research studies. The Ragon Institute team traced the mutation back to a specific commercial supplier and notified the company, which is now taking steps to check all its colonies.
Fuentes builds on the extended evolutionary synthesis, arguing that evolution is a complex mix of biology, ecology, behaviors, chemistry, and history. Anthropologists can combine these approaches for a more nuanced understanding of humanity.
A large proportion of US cancer deaths might be prevented through adopting healthy lifestyles, including quitting smoking and exercising regularly. The study found that individuals who met specific criteria for a healthy lifestyle pattern had a significantly lower risk of developing cancer.
A new study found that bright light exposure increases insulin resistance compared to dim light exposure in both the morning and evening. This could lead to excess blood glucose, weight gain, and a higher risk of diabetes over time. The study suggests that lighting impacts health outcomes.
A new PLOS Medicine article highlights the need for strengthened national health systems, consolidated global emergency response activities, and enhanced research and development to prevent and respond to future infectious disease threats. The study's authors emphasize that system-wide accountability and continuous oversight are crucia...
A study by Jeremy Sanford's lab at UC Santa Cruz identified an extensive malignancy-associated gene expression circuit regulated by IGF2BP3 in pancreatic cancer cells. The protein drives metastasis by influencing the expression of genes involved in cancer biology, including cell migration and proliferation.
A survey of oncologists and palliative care consultants found that most believe writing condolence letters is important in cancer palliative care. The study suggests that this practice should remain personal and not be standardized.
Brandeis scientists have developed a method to genetically identify and manipulate individual cell types in the mouse brain, revealing over 150 distinct brain cell types. This breakthrough enables researchers to activate or deactivate specific genes to study their function without affecting other cells.
Most Arizona biology instructors prioritize teaching facts over helping students accept evolution, according to a new ASU study. The research found that many professors perceive barriers to discussing the topic and often stick to neutral facts, despite recognizing that science can coexist with religious beliefs.
A new study by Boston University School of Public Health researchers found that firearm ownership is closely tied to suicide rates, with states having higher gun ownership levels experiencing higher gun-related suicides. The study analyzed 33 years of data and found that firearm ownership explained 71% of the variation in state-level g...
Drexel researchers found the New York Times' coverage of PTSD from 1980 to 2015 neglected civilian and non-military cases, negatively framing the disorder. This narrow focus can inhibit awareness about PTSD resilience and recovery, and constrain discourse on social determinants of traumatic stress.
A study by Sanford Burnham Prebys Medical Discovery Institute identified a super-oncogenic protein, activating transcription factor 2 (ATF2), that drives the formation of melanoma in mice with BRAF mutations. Inactive ATF2 was found to cause tumors to develop slower than expected, making it a potential indicator of tumor aggressiveness.
Researchers found that surgeons differ in recommending surgery based on how they perceive risks and benefits, rather than just the patient's diagnosis. A surgical risk calculator can lead to more accurate predictions, but does not change a surgeon's likelihood of recommending an operation.
Researchers from the Henryk Niewodniczanski Institute of Nuclear Physics have observed elastic collisions between photons in heavy ion collisions. The study predicts that some deflected photons could hit detectors installed by ATLAS, CMS, and ALICE projects.
Recent studies have identified biomarkers associated with cartilage degradation and new genes linked to osteoarthritis (OA) development. Researchers used a non-invasive mouse model of post-traumatic osteoarthritis (PTOA) to analyze whole-joint gene expression, providing insights into the disease's progression.
Researchers have identified the genes responsible for producing the red pigment in bird species, linking it to detoxification processes and suggesting a link between mate quality and genetic fitness. The discovery provides new insights into the evolution and ecology of red coloration in birds.
A study published in Cancer Epidemiology, Biomarkers & Prevention found that consuming high amounts of saturated fat or low amounts of mono- and polyunsaturated fats during adolescence is associated with higher breast density in young adulthood. This increased risk of breast cancer was observed after adjusting for multiple variables.
Lomonosov Moscow State University scientists have developed a new method to extract DNA from various organisms. This breakthrough could lead to the creation of preventive vaccines against infectious diseases, allergies, and cancers.
Teenagers who experienced childhood family adversity are more likely to be bullied at school and develop depressive symptoms. However, supportive family or friends in early adolescence can help reduce depressive symptoms later on.
Researchers have identified brain cells in fruit flies that regulate sleep drive, which becomes more active when flies are kept awake. These findings may offer insights into human sleep disorders and potential new strategies to promote long-lasting sleep for those with chronic insomnia.
A study published in Science reveals that a molecule called ppGpp enables bacteria to repair damage to their DNA, including that caused by antibiotics. Adjusting the action of ppGpp may make bacteria more vulnerable to existing antibiotics, potentially yielding future solutions for antibiotic resistance and degenerative diseases.
Researchers found that Manduca sexta moths prefer flowers with nectar that matches the length of their proboscis, resulting in optimal energy gain. The moths use scent to guide themselves to these ideal flowers, which is supported by an innate preference.
A study published in the Journal of Neurology found that brain scans of dementia patients with coprophagia showed significant neurodegeneration, particularly in the medial temporal lobe and amygdala. The researchers also noted that behavioral modifications and antipsychotic medication were effective in treating the behavior.
Research by University of Notre Dame found that companies with higher female representation on boards engage less in mergers and acquisitions, identifying potential challenges in deals. The study suggests diverse board dynamics lead to more thorough discussions, increasing likelihood of deal delays or shelving.
A simple public health intervention helped prevent many cases of chronic kidney disease (CKD) in Pakistan by training community health workers and general practitioners on healthy lifestyle advice. After 7 years, individuals with the combined intervention had preserved kidney function, while those who received usual care experienced a ...
Researchers found that combining TXA delivery methods reduced blood loss by 37% compared to IV alone following TKR. The study showed no thromboembolic complications, with one patient requiring a postoperative blood transfusion.