Articles tagged with Human Gut Microbiota
A study found that human gut bacteria can transmit lean or obese traits to mice depending on their diet, highlighting the importance of diet in shaping gut microbiota. The researchers identified specific bacterial species that play a role in metabolism and obesity, paving the way for personalized probiotic therapies.
Fructooliogosaccharides, found in chicory and other fruits/vegetables, provide prebiotic properties that stimulate gut microbiota production. They also enhance flavor, reduce sugar content and increase calcium absorption, supporting bone health.
A study published in PLOS ONE suggests that children with autism spectrum disorder (ASD) have lower diversity of gut bacteria and decreased amounts of three critical bacteria. This finding implies that a diverse gut microbiome is essential for maintaining a robust bacterial community, and may be linked to the development of ASD symptoms.
A new grant will fund research into the relationship between diet and specific microbes, genes, and colorectal cancer. The study aims to associate red meat intake with the gut microbiome on a population scale.
A study found that a Mediterranean diet causes a decrease in total cholesterol and LDL cholesterol levels. Each individual has a unique microbial profile, like a fingerprint, which remains true even after diet manipulation.
Research from Massachusetts General Hospital finds that gastric bypass changes microbial populations in obese mice, leading to weight loss and improved metabolism. Transferring altered microbiota into germ-free mice reproduced the effects of bypass surgery.
Researchers from NYU College of Dentistry and School of Medicine will explore the role of intestinal microbiota in promoting pancreatic carcinogenesis. The study aims to determine whether endogenous gut bacteria can affect pancreatic oncogenesis and identify potential targets for prevention and treatment.
Researchers found that reintroducing normal microbial diversity can eliminate vancomycin-resistant enterococci (VRE) from the intestinal tracts of mice and potentially humans. The study suggests that certain bacterial species, such as Barnesiella, play a key role in preventing colonization by VRE.
A study of young twins in Malawi reveals that dysfunctional gut microbes contribute to severe acute childhood malnutrition. The researchers found that feeding malnourished children a high-calorie, nutrient-rich food temporarily improved their gut microbiomes, but the benefits were short-lived. The findings suggest that repairing gut mi...
Researchers found a human gene associated with the presence of Prevotella bacteria in the gut, which could have implications for treating diseases like Crohn's. The study suggests that genetic variations may influence the makeup of the gut microbiota.
A University of Oklahoma study analyzed ancient DNA from human fecal samples to understand changes in the human gut microbiome. The results suggest that the last 100 years have seen a major shift in the human gut microbiome, with broader implications for modern health.
Research published in PLOS ONE reveals that extinct human microbes from archeological sites closely resemble those found in present-day rural African communities. The study suggests that the modern cosmopolitan lifestyle resulted in a dramatic change to the human gut microbiome.
A recent study found that mice carrying a set of friendly microbes fail to develop a proper immune system, highlighting the importance of host-specific microbiota. The researchers suggest that a coevolved relationship between humans and their gut microbiome may be compromised by modern lifestyle factors.
A team of scientists from the Gladstone Institutes has contributed to a groundbreaking study that mapped the human microbiome, revealing over 10,000 microorganisms that live on and inside humans. The researchers used advanced DNA-sequencing techniques to identify individual microbes and their roles in human health.
The Human Microbiome Project Collection provides a comprehensive baseline of the microbial diversity at 18 human body sites, including reference genomes and metagenomic sequences. The studies examine relationships between the microbiome and host health, shedding light on conditions such as Crohn's disease and psoriasis.
A team of scientists led by Washington University's Jeffrey I. Gordon will investigate the complex relationship between diet, gut microbes and immune system in severely malnourished children. The research aims to discover novel dietary and microbial therapeutics to target infants and children living in countries with rampant malnutrition.
A study suggests that eating pistachios can increase beneficial bacteria in the gut, potentially supporting digestive health. Researchers found a stronger effect on gut microbiota composition in those who ate pistachios compared to almonds.
A study analyzing human gut microbes as a complex system reveals patterns corresponding to excess body weight. The researchers found organizational shifts away from a normal state in the gut flora of obese individuals, which may account for their increased energy extraction capacity.
Researchers have sequenced the genome of Lactobacillus reuteri, a gut bacterium that has evolved unique adaptations to specific hosts. The study provides new insights into how bacteria establish and maintain mutually beneficial relationships with their hosts.
Research reveals that gut bacteria can exert control over metabolic functions of organs, including the liver, through changes in the microbiota. The study found that colonization with specific bacteria triggered changes in liver metabolic profiles, including glycogen and triglyceride production.
A pair of clinical trials found that two weeks of rifaximin treatment significantly reduced IBS symptoms, including bloating and abdominal pain. The benefits persisted for 10 weeks after treatment was stopped, suggesting a potential underlying cause of IBS: alterations in gut bacteria.
A University of Illinois study shows that sulforaphane, a powerful cancer-fighting agent in broccoli, can be released by bacteria in the lower gut and absorbed into the body. This discovery raises the possibility of enhancing the activity of these bacteria to increase broccoli's cancer-preventive power.
Dr. Blaser and his team will investigate whether changes in the human microbiome as a result of antibiotic use have fueled the obesity epidemic. The grant will assess the roles of gastric and colonic microbiota related to hormones and metabolism in both humans and mice.
The National Institutes of Health has awarded $42 million to expand eight demonstration projects investigating the link between changes in the human microbiome and health, as part of the Human Microbiome Project. The expanded studies will also support technology development to improve microbiome identification and characterization.
Researchers at EMBL discover a reference gene set for the human gut microbiome, cataloging 3.3 million microbial genes and shedding light on their role in maintaining health. This breakthrough enables non-invasive stool samples to be used as a measure of health, potentially leading to new treatments.
The Human Microbiome Project is expanding its efforts to understand the relationship between the microbiome and human health. The NIH has awarded over $42 million to fund sequencing centers and disease projects, including studies on psoriasis, bacterial vaginosis, obesity, and Crohn's disease.
A recent study by Cecil Lewis at the University of Oklahoma reveals that ancient microbes can provide insights into modern human health. The researchers analyzed 1,300-year-old feces from Central Mexico and found them to be more geographically structured than modern microbiomes.
The study found that gut microbiota play a significant role in regulating weight and energy balance. Researchers suggest that manipulating the gut microbiota could be a useful strategy for treating obesity. However, more research is needed to establish the relationship between gut bacteria and obesity.
The study reveals a diverse population of over 60,000 genes in the human colon microbiome, including enzymes that help humans digest food. The findings suggest that bacteria in the colon co-evolved with their human host, contributing to our well-being and potentially leading to diseases like inflammatory bowel disease.