Researchers discovered a probiotic strain, Bifidobacterium animalis subsp. lactis B960, that enhances the glucose-lowering effects of glibenclamide with minimal degradation. This combination therapy reduces fasting blood glucose levels and improves pancreatic function while alleviating hepatotoxicity.
A recent review of bamboo consumption found promising health benefits, including improved metabolic health, reduced inflammation, and antioxidant activity. However, caution is advised due to potential risks associated with raw or improperly prepared bamboo.
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Researchers develop a novel approach to precisely encapsulate individual probiotics into microgels, enhancing survival and targeted delivery in the gastrointestinal system. The study demonstrates improved therapeutic efficacy in treating IBD using this technology.
Researchers from Shinshu University used ribosome engineering to modify probiotic Lacticaseibacillus rhamnosus GG, resulting in increased colonization and enhanced immune stimulation. The engineered bacteria exhibit altered surface protein expression and induce higher activation of immune cells.
A new study found that supplementing exclusively breastfed infants with probiotic Bifidobacterium infantis EVC001 between 2-4 months can restore beneficial bacteria in their gut. This approach may have lasting benefits for breastfed infants, even after supplementation stops.
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A study by Shinshu University researchers highlights the potential of probiotics, prebiotics, and synbiotics to enhance livestock gut health, immunity, and growth while reducing dependence on antibiotics. The findings support sustainable livestock management and contribute to reducing antimicrobial resistance risks.
The winners of the Applied Microbiology International Horizon Awards 2025 have been recognized for their groundbreaking contributions to global challenges through applied microbiology. The awards celebrate excellence across various domains, including drug discovery and sustainable agriculture.
A healthy microbiome promotes overall well-being, influencing areas like cognition, mood, immunity, and disease susceptibility. By incorporating proven dietary interventions, regular exercise, stress reduction, and adequate sleep, individuals can harness their microbiome for optimal health.
Researchers from the University of South Australia explore the connection between the gut and brain to decipher their role in mental health and wellbeing. The study found that changes in the gut microbiome can directly affect brain chemistry, suggesting a potential link between gut health and mental illness.
Research reveals that Bifidobacterium breve in pregnant mothers regulates the placenta's hormone production, reducing complications and improving fetal growth. The study opens up a new approach to assessing pregnancy health through gut microbiome analysis.
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The University of California - Riverside is receiving a $2 million grant to investigate how gut microbes interact with their human hosts to influence health. The research aims to create next-generation probiotics that strengthen the gut microbiome, improve vaccine effectiveness, and prevent infections.
A UC Berkeley professor and her team have discovered gene clusters in the oral microbiome that produce molecules helping good bacteria stick to teeth, outcompeting acid-producing cavities. The researchers plan to introduce these gene clusters into healthy bacteria to form strong biofilms, reducing cavities.
Researchers found that a compound produced by Lactobacillus bacteria can reverse liver and gut damage caused by aflatoxin exposure. The molecule, 10-hydroxystearic acid, activated PPARα signaling to repair liver tissue and support gut health.
Institute for Systems Biology researchers use microbial community-scale metabolic models to simulate C. diff behavior in human gut microbiome samples. They accurately predict colonization states, susceptibility, and response to probiotics, offering a path to prevent C. diff before it starts.
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Researchers have mapped the microbiome of agri-food systems, revealing how diverse and balanced microbes keep our food safe, nutritious, and sustainable. The map highlights areas where targeted interventions such as probiotics and biofertilizers can improve food quality and reduce antibiotic use.
Researchers have mapped microbial networks underpinning healthy food systems, highlighting the need for integrated approaches to address climate crisis, antibiotic overuse and pesticide reliance. This work is driving microbiome-based solutions for animal, human and environmental health.
Four leading Japanese corporations in the health and nutrition sectors have joined forces to advance microbiome science. The event aims to explore recent research and development achievements, engage with industry innovators, and promote practical applications of fundamental research.
Researchers created an 'encyclopedia of sugar utilization pathways' in 263 Bifidobacterium genomes. This resource helps predict which strains thrive in different conditions, enabling personalized probiotics to match children's lifestyles and dietary needs. The study suggests a potential solution to improving outcomes for preterm infants.
A recent study analyzed 95 commercial probiotic products from China, revealing low labeling accuracy and high prevalence of antibiotic resistance genes in Enterococcus strains. The findings suggest that low-quality probiotics can disrupt intestinal homeostasis and serve as a reservoir for ARGs. Researchers emphasize the need for carefu...
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A study by HZI researchers showed that specific strains of E. coli can displace multi-resistant bacteria from the gut, potentially preventing infections and containing their spread. The strains, which were tested in a mouse model, also proved effective against other resistant strains when combined with Klebsiella oxytoca.
Scientists have discovered that certain species of gut bacteria can absorb PFAS, potentially protecting against its harmful effects. The researchers plan to develop probiotic dietary supplements to boost the levels of these helpful microbes in our gut.
New research warns against widespread use of Fecal Microbiota Transplants (FMT) due to potential for long-lasting, unintended health consequences. Mismatches in gut ecosystems can lead to changes in metabolism, behavior, and energy balance.
A team of researchers at Binghamton University has developed a dissolvable battery using probiotics, which can provide a safe and sustainable energy source for transient applications. The battery utilizes electricity-producing bacteria that are commonly found in the human digestive system and are considered biocompatible.
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Researchers have discovered that a bacterial probiotic helps slow the spread of stony coral tissue loss disease (SCTLD) in already infected wild corals in Florida. Applying the probiotic treatment across entire coral colonies helped prevent tissue loss, providing a more lasting protection than traditional antibiotics.
A study published in Cell Metabolism finds that a combination of gut bacteria and acetate reduces obesity in mice. The researchers discovered that the specific combination of Bacteroides species and acetate leads to increased fat burning and reduced sugar storage, resulting in weight loss.
A new study suggests that multi-strain probiotics can alleviate chemotherapy-related side effects such as fatigue, nausea, and weakness. Probiotics have been shown to improve blood urea nitrogen levels and enable patients to perform daily activities more independently.
Researchers found that new strains of Cutibacterium acnes, a species believed to contribute to acne development, are acquired during the early teenage years. This transitional stage could be the best window for introducing probiotic strains of C. acnes to prevent acne.
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Researchers have discovered a new probiotic bacterial strain that is 15% more effective in treating giardiasis than the existing strain. The strain, Lactobacillus johnsonii CNCM I-4884, has significant anti-Giardia activity and can transform conjugated bile salts into toxic compounds for the parasite.
A recent study found that a probiotic supplement called Lactobacillus helveticus CCFM1320 can improve sleep quality in patients with insomnia. The probiotic enhanced the methylation of N-acetylserotonin, leading to normalized circadian rhythm gene expression.
The summit will highlight the latest research on coronavirus, plant-based protein, and probiotics, with a focus on their applications in clinical practice. Studies have found that COVID-19 affects the gut microbiome in children, while dietary protein like S100B may promote a healthy microbiome.
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Researchers developed synbiotic chocolates fortified with probiotics and prebiotics, showing improved gut microbiome balance and probiotic survival rates. The study found that the orange-flavored chocolates had a softer texture and more luxurious bite experience.
A new enzyme discovered in a gut bacterium has the potential to synthesize unique glycans with prebiotic properties, supporting gut health. The novel β-galactosidase could drive innovation in prebiotic products and contribute to developing new treatments for diseases like Chagas disease.
Researchers developed a synthetic microbiome therapy using limited strains of gut bacteria to effectively protect against C. difficile infections in mice. The treatment was as effective as traditional fecal transplants and had fewer safety concerns, offering a new alternative for treating this notoriously difficult-to-treat infection.
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Research from RIKEN Center for Integrative Medical Sciences found that infant gut bacteria are associated with food sensitivities and allergies, particularly to eggs. The study suggests that probiotic supplements, such as Bifidobacterium, may help prevent food allergies in at-risk infants.
Researchers at the University of Surrey propose a new approach to treating inflammatory diseases using personalized probiotic therapies. By analyzing large-scale computer models and computational methodologies, they can identify potential targets and design tailored treatments.
Researchers found that a person's microbiome signature can predict the likelihood of Enterobacteriaceae colonization. Fiber-rich foods support the growth of beneficial Faecalibacterium, which produce short-chain fatty acids protecting against infection.
Hebrew SeniorLife has launched a 18-month clinical food trial to test the combination of probiotics and prebiotics for managing bone health in women aged 60. The study, funded by the National Institute on Aging, aims to investigate the underlying mechanisms leading to age-related bone loss.
A study by the National Center for Supercomputing Applications aims to create personalized nutrition plans based on an individual's unique gut microbiome. The researchers used Illinois Computes to analyze metabolomic data and develop a database of metabolites that can help diagnose diseases more efficiently.
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A review of probiotics for restoring antibiotic-disturbed gut microbiota found limited conclusive evidence. While certain probiotics can reduce clinical symptoms like diarrhea and C. difficile colitis, the lack of standardization in measuring microbiota disruption and recovery hinders conclusions.
A UC Riverside study found that probiotic supplementation can reduce the negative impacts of PBDEs on neurodevelopment, behavior, and metabolism in mouse offspring. The researchers discovered that LR treatment helped normalize body weight gain and tooth eruption timing, as well as improved glucose metabolism and insulin levels.
Researchers at WashU Medicine engineered a probiotic that delivers immunotherapy directly to the gut, shrinking tumors in mice. The probiotic uses a yeast-based system to produce immune checkpoint inhibitors, potentially treating hard-to-reach cancers.
The winners of the Applied Microbiology International Horizon Awards 2024 have been named, including the One Health Microbiome Center at Penn State and researchers Dr. François Thomas and Dr. Helen Onyeaka.
Researchers have found that specific E. coli bacteria in the gut promote colon cancer by binding to intestinal cells and releasing a DNA-damaging toxin called colibactin. This binding is made possible by bacterial pili and adhesins, which can be targeted to prevent tumor development.
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A new perspective paper emphasizes the critical role of diet in shaping the efficacy of prebiotics and probiotics. The authors found that diet significantly affects gut microbiome composition and function, potentially impacting the success of these interventions. Researchers are urged to collect data on participants' background diets a...
Researchers at University College Cork found that wild birds' gut microbiome impacts their growth, weight, and survival. The study manipulated the birds' microbiome by feeding them beneficial bacteria Lactobacillus kimchicus.
A new framework outlines essential criteria for establishing prebiotic status, emphasizing selective utilization, measurable health benefits, and safe use. The proposed guidelines aim to promote clarity and informed decision-making around prebiotic products.
A research team developed an RNA-based sensor platform that can regulate gene expression in bacteria, mimicking natural biological interactions. The START platform enables tunable control over sensor response and detection of various molecules, including drugs and proteins.
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A new study has found a natural probiotic in the microbiomes of UK newborns, which could be used to develop personalized infant therapeutic probiotics. The researchers analyzed stool samples from 1,288 healthy infants and found that one of the pioneer bacteria was genetically adapted to utilize breast milk nutrients and block pathogens.
Researchers at Tecnolat have identified three Lactobacillus strains with probiotic properties, safe for consumption, and beneficial to human health. These strains can also enhance the sensory diversity and microbiological quality of traditional Brazilian cheeses.
Researchers discovered a unique probiotic strain, Bifidobacterium bifidum BB1, that strengthens intestinal barrier function and protects against harmful bacteria. This strain may lead to the development of novel therapies for patients with inflammatory bowel disease and other inflammatory conditions.
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A study in mice found that the bacteria Bifidobacterium breve supports healthy brain development in fetuses, improving nutrient transport and cell processes. This discovery suggests using probiotics during pregnancy may support fetal brain health and future treatments for growth restriction could focus on maternal gut health.
A new study by Ohio State University Wexner Medical Center found that probiotics can improve the immune system and behavior of both mothers and their offspring during pregnancy. Probiotics may also help counteract negative effects of prenatal stress, such as changes in brain inflammation and amino acid metabolism.
Researchers from Poland developed an ice cream made from mare's milk blended with cow's cream, which may have beneficial probiotic qualities. The study found that this unique combination could lead to the creation of synbiotic ice cream production, potentially offering a new approach to probiotic supplements.
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New studies from the University of Illinois found that adding honey to yogurt supports the survival of probiotic bacteria in the gut. The research suggests that pairing honey with yogurt is a delicious and healthy way to support digestive health and gut microbiome, with potential benefits for mood and cognition.
Beneficial bacteria like Bacillus subtilis possess memory and express genes associated with colonization and symbiosis for generations after being detached from their host. This multigenerational inheritance stabilizes interactions with their host, enabling efficient recolonization.
The team created stable microbial therapeutics using synthetic extremophiles, maintaining potency and function over time despite extreme temperatures and harsh manufacturing processes. These formulations have potential applications in healthcare, agriculture, and space exploration.
Researchers at MIT have developed a new way to make microbes hardy enough to withstand industrial processing, high temperatures, radiation, and long-term storage. The method involves mixing bacteria with food and drug additives, resulting in stable formulations that can be used in various applications.
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Scientists identified Roseomonas mucosa as a beneficial bacterium that relieves eczema symptoms in adults and children. The probiotic is available over-the-counter and has shown significant improvement in eczema severity, skin barrier function, and quality of life.
A probiotic spray method has been developed to improve hatchability and health in chicks without using antibiotics. The patented method has shown an approximately 5% increase in hatchability and healthier chick quality.
Researchers in Brazil have developed bread with probiotic yeast that may help combat asthma by reducing airway inflammation and hyperresponsiveness. The bread's probiotic properties were shown to attenuate asthma symptoms in mice, suggesting potential for a new treatment approach.