A review and meta-analysis of previous studies found that probiotic consumption is associated with a reduced risk of antibiotic-associated diarrhea. The study analyzed 82 randomized controlled trials involving 11,811 participants, finding a 42% lower risk of developing diarrhea with probiotic use.
A RAND Corporation study found that taking probiotics can significantly reduce the risk of developing diarrhea caused by antibiotics. The study, which pooled data from over 100 research studies, showed a 42% lower risk of antibiotic-associated diarrhea with probiotic use.
Researchers have developed a model gastric system to evaluate probiotic survival, finding that some bacteria strains thrive in fermented milks. The study suggests that certain lactococcal and enterococci strains can resurrect their viability in the small intestine.
Sigma-Tau Pharmaceuticals is sponsoring a Patient Assistance Program (PAP) to provide financial assistance for VSL#3 DS, a prescription-only double strength probiotic formulation, to eligible patients with ulcerative colitis or ileal pouch. The program aims to make it easier for those in need to access the probiotic medical food.
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Researchers at NOAA's Milford Laboratory have isolated a new probiotic bacterium, OY15, that significantly improves larval survival in oyster hatcheries. The study confirms the protective effect of naturally-occurring probiotic bacteria against bacterial disease and promotes healthy growth.
Research published in the FASEB Journal reveals that intestinal microbiota play a crucial role in determining the outcome of heart attacks in rats. The study found that probiotics can tilt the scales in favor of improved cardiovascular health, reducing heart attack risk and improving recovery from myocardial infarction.
Researchers have found that adding a specific protein from Listeria to a probiotic can decrease the risk of infection by 46%. The breakthrough could lead to the development of a pill or drink to prevent Listeria infections, primarily affecting pregnant women and those with weakened immune systems.
Researchers found that probiotic treatment increased interferon levels and reduced the number of infections in ICU patients. Probiotics also helped to shift the balance of the immune system, reducing Th2-associated factors and promoting a healthier response.
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Researchers found that taking a probiotic before radiation therapy can protect the intestine from damage in mice, and may help prevent similar problems in human patients. The probiotic Lactobacillus rhamnosus GG protected the lining of the small intestine in mice exposed to radiation.
Researchers found that probiotics significantly reduce the incidence of antibiotic-associated diarrhea and Clostridium difficile-associated diarrhea. Probiotic therapy has been shown to be effective in treating various GI conditions, including ulcerative colitis, psoriasis, and chronic fatigue syndrome.
Researchers at the University of Bristol identified a probiotic strain that can thrive in high-iron environments and reduce inflammation associated with IBD. The discovery offers hope for developing novel treatments for active intestinal disease.
Researchers have developed a special type of biopolymer that protects probiotic bacteria from the acidic stomach environment and delivers them safely to the intestines. This innovation could lead to better quality probiotic food products and increase calcium absorption, benefiting gut health and bone structure.
Probiotic bacteria have limitations in conventional production processes. Researchers at TUM developed a gentle method using low-temperature vacuum drying, which is energy and cost-efficient. This process improves storage stability, allowing more active bacteria to remain in products until consumption.
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Researchers propose a new field of microbial endocrinology linking probiotics to neurological function. Studies show that neurochemicals produced by gut microbes can influence behavior and immune response. Probiotic intestinal microbiota may deliver beneficial effects through direct uptake from the gut.
A study by Caroline Karlsson found that rats fed a specific lactic acid bacteria HEAL19 had significantly less weight and inflammation compared to those without the bacteria. Additionally, babies born vaginally have lactobacilli in their gut flora as early as two days after birth.
Researchers identified a new probiotic bacteria-derived soluble protein that provides therapeutic protection against intestinal inflammation. The protein, p40, was delivered to the colon and protected mice from colitis through an EGFR-dependent mechanism.
A new probiotic treatment has been shown to reduce the rate of recurrent urinary tract infections in women. The study found that women who received a Lactobacillus crispatus intravaginal suppository had lower infection rates compared to those who received a placebo.
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Research suggests that probiotic E. coli Nissle 1917 can reduce negative effects of AIEC in Crohn's patients, modulating inflammatory immune proteins. The study emphasizes the potential of EcN in IBD treatment and its use as a therapeutic option for CD patients with pathogenic AIEC.
A strain of probiotic bacteria, Bifidobacterium bifidum CECT 7366, has been identified as effective in treating ulcers caused by Helicobacter pylori. The probiotic strain demonstrated significant inhibition levels against H. pylori and partially relieved damage to gastric tissue.
A genetically tweaked probiotic has nearly eliminated colon inflammation in mice with colitis, halting disease progression by 95%. The novel probiotic strain may prove useful in colon cancer, another disease triggered by inflammation.
Specially designed probiotics can modulate host fat cells, potentially leading to specialized probiotics for obesity prevention or treatment. Ingesting live bacteria influences metabolism at remote sites in the body.
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A systematic review found that probiotics shortened diarrhoea episodes by around a day and reduced the risk of prolonged episodes by 59% in patients with diarrhoeal diseases. No serious adverse effects were reported.
A randomized, double-blind study found that mothers who consumed probiotic milk during and after pregnancy had a 40% lower incidence of eczema in their children. The study suggests that the probiotic bacteria may have prevented the development of eczema, with less severe cases in children who did develop eczema.
A new study found that daily use of probiotics reduced VAP infections by almost half and decreased antibiotic consumption, leading to fewer Clostridium difficile infections. The probiotic therapy was found to be safe with no side effects.
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The study found a 19 percent decrease in common infections among children who drank DanActive, with specific reductions in gastrointestinal and upper respiratory tract infections. However, the reduction did not result in fewer missed school days or activities.
Daily probiotic cheese consumption boosts natural and acquired immunity in older adults by activating NK blood cells and increasing phagocytic activity. The study aims to thwart immunosenescence, an age-related deterioration of the immune system that increases susceptibility to infections and cancer.
A probiotic strain, B. lactis HN019, attenuates IL-8 mRNA level and reduces pro-inflammatory responses in intestinal epithelial cells. It also internalizes into cells and excludes enteropathogen adhesion, contributing to homeostasis of the intestinal epithelium.
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A randomized, controlled study found that probiotics supplemented in enteral feedings of extremely low birthweight infants (ELBW) led to better weight gain compared to those without supplementation. No adverse effects were reported.
A meta-analysis published in the World Journal of Gastroenterology suggests that probiotics are an auxiliary medicine for inducing and maintaining remission in ulcerative colitis. The study concluded that probiotics should be considered as a treatment option for this chronic disease.
A new thesis at the University of Gothenburg reveals that a probiotic, Lactobacillus plantarum, has no effect on Salmonella bacteria. Researchers found that the probiotic did not reduce diarrhoea or shorten the duration of infection in patients with Salmonella.
Research published in World Journal of Gastroenterology found that fermented milk with Streptococcus thermophilus CRL 1190 exhibited therapeutic effects on chronic gastritis, particularly by modulating the immune response and increasing the thickness of the gastric mucus gel layer. This natural alternative may offer a potential treatme...
Hypnotherapy has been shown to significantly improve irritable bowel syndrome (IBS) symptoms in a majority of cases, with some patients experiencing complete relief. Probiotics can also be an effective option, but the efficacy depends on specific strains and clinical trial evidence.
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Recent studies have identified probiotic microbes that produce anti-inflammatory compounds, such as butyric acid, which may treat inflammatory bowel disease. Strains like Faecalibacterium prausnitzii and Butyricicoccus pullicaecorum have shown promise in restoring normal gut bacteria levels and alleviating symptoms.
A study of mucosal biopsies from patients with ileal pouch-anal anastomosis reveals protein expression changes in pouchitis and antibiotic-induced remission. Proteomic analysis identifies novel biomarkers for disease activity, diagnosis, and prognosis.
A probiotic bacterium, Bacillus polyfermenticus, has been shown to effectively treat colitis in mice by promoting the growth of new blood vessels. The study found that the bacteria increased angiogenesis, a process necessary for wound healing, and reduced inflammation in affected tissues.
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Researchers from the University of Helsinki have shed light on the origin of probiotic mechanisms, promoting product development in the food industry. The study found that LGG probiotics have a fundamental role in binding with human intestinal mucus, enabling health-promoting effects.
A clinical trial of kefir in young children using antibiotics found no benefit in preventing diarrhea. However, the study suggests that kefir may help healthier children, and more research is needed to confirm this finding.
A study published in the Journal of Gastrointestinal Surgery found that taking probiotics after Roux-en-Y gastric bypass surgery can help obese patients shed more pounds. Probiotics also helped improve levels of vitamin B-12, which are often deficient after gastric-bypass surgery.
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A randomized controlled trial found that adding probiotics to conventional high-energy ready-to-use therapeutic foods did not improve nutritional cure rates or reduce mortality in severely malnourished African children. However, the study suggests a possible observation of reduced outpatient mortality in HIV-positive children.
A new study found that taking probiotics during pregnancy can help reduce the risk of obesity in women, particularly central obesity and body fat percentage. The study involved 256 pregnant women who received either dietary counselling alone or with daily capsules of probiotics containing Lactobacillus and Bifidobacterium.
Researchers used probiotics to protect animals from diseases such as mastitis and salmonellosis, demonstrating their potential to prevent and treat human diseases. The study identified specific bacterial species and mechanisms of action that could lead to the development of new treatments.
A researcher at Northwestern University has developed a new oral vaccine using probiotics that induces a powerful immune response, protecting against diseases such as anthrax and breast cancer. The vaccine harnesses the body's primary immune force in the small intestine, bypassing traditional injection methods.
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Researchers found that four strains of probiotics, including E.faecalis, alleviated symptoms of experimental colitis in mice. The study suggests that different probiotics have varying effects on the condition, with E_faecalis showing superior benefits.
Researchers found that applying a probiotic bacterial solution in place of antiseptics effectively prevents respiratory illness in ventilated patients. The friendly bacteria, Lactobacillus plantarum 299, has no negative side effects and does not contribute to antibiotic-resistant strains.
Several new studies suggest that probiotics can help improve symptoms of Irritable Bowel Syndrome (IBS), including constipation or diarrhea. The research findings indicate that probiotics may be effective in normalizing bowel movement frequency, reducing IBS-related symptoms such as abdominal pain and bloating.
Researchers found that probiotic bacteria can efficiently mature monocyte-derived dendritic cells, leading to the production of specific cytokines. The maturation process was triggered by different bacterial strains, with some inducing pro-inflammatory and others anti-inflammatory responses.
A Finland research group investigated the effect of a three weeks probiotic LGG intervention on serum global lipidomics profiles in healthy adults. The result showed decreases in certain lipids and increases in triacylglycerols.
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A pilot study found that Yakult(R) altered intestinal fermentation patterns, reducing symptoms of small intestine bacterial overgrowth (SIBO). Probiotic treatment reversed ERBHAL in 64% of patients, improving symptoms.
A recent study published in PLOS Pathogens reveals that probiotic Bifidobacterium infantis 35624 can limit damage from infection-related inflammation. The research demonstrates the anti-inflammatory and pathogen protection benefits of this strain, suggesting potential benefits beyond gastrointestinal health.
Studies have found that Bifidobacterium infantis 35624 (Bifantis) can normalize gut function and reduce IBS symptoms by up to four weeks. Researchers believe that imbalances in gut microflora lead to chronic inflammation, making Bifantis a potential new path for treating inflammatory diseases like arthritis.
A daily dose of probiotic can modify the immune system's response to grass pollen, a common cause of seasonal hay fever. This change was observed in a pilot study with small numbers of patients, but it may not have an immediate effect on symptoms.
Bariatric surgery shows promise as a treatment for adolescent obesity, with per-oral suturing procedures offering a safe and effective alternative. Probiotics also aid in weight loss and GI quality of life after gastric bypass surgery.
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A study found that probiotics have anti-inflammatory potential in healthy adults, characterized by decreased serum CRP levels and reduced production of proinflammatory cytokines. This suggests a possible therapeutic application for probiotics in the prevention or treatment of inflammatory diseases.
A recent study investigated the effect of probiotic bacterial combinations on cytokine production in vitro. The results showed that different bacteria compete with each other during host cell interactions, and novel probiotic strains are more potent inducers of Th1 type cytokines.
Patients with severe acute pancreatitis who received probiotics had higher mortality rates than those receiving a placebo. The study suggests that probiotics may not be effective in preventing infectious complications and modulating the immune system in these patients.
A new study published in Molecular Systems Biology reveals that probiotics can significantly alter the biochemistry of gut microbes and affect metabolism. Researchers found that different probiotic strains triggered distinct biochemical changes, including modifications to bile acid metabolism, which could influence fat absorption.
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A review of 13 randomized controlled trials found that only Bifantis showed significant improvement in IBS symptoms. The study evaluated the safety, efficacy, and tolerability of probiotics for IBS treatment.
Researchers found that combining Lactobacillus rhamnosus GG probiotic strain with lower doses of hyperimmune bovine colostrum (HBC) provides protection against rotavirus infection, effective as high-dose HBC alone. This combination therapy could help relieve the immense disease burden posed by rotavirus in developing countries.
Scientists discover probiotics can reduce Salmonella bacteria in pigs, potentially cutting food poisoning cases. The new technique uses 3D models to test probiotic effects without live animals.
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Researchers found that Bifantis delayed the onset of artificially induced arthritis and resulted in less severe arthritic symptoms. In a second study, Bifantis increased the numbers of immune cells controlling the response to harmful pathogens like Salmonella, limiting inflammation.