Articles tagged with Probiotics
A phase II/III study found that a high concentration of multi-strain probiotic helped reduce mild to moderate episodes of chemotherapy-induced diarrhoea (CID) in cancer patients. The probiotic also reduced levels of inflammatory markers, although it did not meet its primary endpoint.
A new study by MIT researchers shows that combining antibiotic drugs with probiotics can eradicate two strains of drug-resistant bacteria that infect wounds. The probiotic bacteria were encapsulated in a protective shell of alginate to prevent them from being killed by the antibiotics.
A NIH study found that probiotic Bacillus eliminates Staphylococcus bacteria, preventing its growth in the gut and nose of healthy individuals. The researchers identified fengycins, a specific class of lipopeptides, as the substance responsible for inhibiting S. aureus sensing system.
Researchers found a correlation between the type and severity of cold symptoms and the mix of bacteria living inside the nose. Six different patterns of nasal microbiomes were identified, each associated with differences in symptom severity and viral load. Probiotics did not have an impact on cold symptoms or nasal microbiomes.
Researchers have created a stable encapsulation system using cellulose and alginate to protect probiotics from stomach acid, allowing them to survive until reaching the intestine. This breakthrough may lead to more effective treatments for conditions like diarrhea and inflammatory bowel disease.
A systematic review found that healthy infants and children taking probiotics are 29% less likely to receive antibiotics. Probiotics may reduce antibiotic use by reducing the incidence and duration of infections, making them a potential tool for physicians as an alternative to antibiotics.
A review of twelve studies found that probiotics reduced antibiotic prescriptions by 29-53% in infants and children. The study suggests that probiotics may be a way to combat antibiotic resistance, with potential mechanisms including immune regulation and pathogen inhibition.
A new study challenges the effectiveness of probiotics in boosting digestive health. Researchers found that many people's gut tracts prevent standard probiotics from successfully colonizing them. Additionally, taking probiotics after antibiotics may delay the return of normal gut bacteria and gene expression.
Researchers found that probiotics' effects on humans and microbiomes vary greatly from person to person. Personalized treatment was shown to have significant benefits in addressing adverse side effects of antibiotics. The study's results suggest a tailored approach to probiotic use, potentially leading to improved health outcomes.
Research published in Applied and Environmental Microbiology found that probiotics increased the severity of cryptosporidiosis in mice, defying initial hypotheses. The study suggests that manipulating gut microbiota may hold potential for developing probiotics to mitigate the disease.
Researchers at Wake Forest School of Medicine developed a probiotic cocktail from infant feces that modulated the gut microbiome and enhanced SCFA production in mice and human feces. This finding suggests these human-origin probiotics could be used to treat diseases associated with gut microbiome imbalance.
Researchers found a significant connection between probiotic use, bacterial overgrowth in the small intestine, high levels of D-lactic acid, and brain fogginess. The study suggests that excessive probiotic use can lead to severe bloating and disorienting brain fog.
A new study reveals that fertilizing plants can destroy the beneficial microbiomes on their leaves, making them more susceptible to disease. Researchers found that low doses of beneficial microbes are often more effective in protecting plants from infection than higher doses.
Researchers found that germ-free mice exhibited reduced inflammation and atrophy compared to specific pathogen free mice, while probiotic administration improved epithelial thickness. Probiotics also reduced the severity of chemotherapy-induced oral mucositis in mice.
Researchers found that a mother's microbiome determines the risk of autism and other neurodevelopmental disorders in her offspring. By manipulating the microbiome through diet or probiotics, it may be possible to prevent autism-like disorders.
A recent study found that only 2% of trials assessing the safety or efficacy of probiotics, prebiotics, or synbiotics adequately reported key safety components. The researchers concluded that the lack of safety data makes it challenging to accurately determine their safety profile and make informed decisions for patients.
Researchers have found that probiotics can significantly reduce bone loss in older women, halving the rate of bone degeneration compared to those who received a placebo. This discovery has important implications for preventing fractures among the elderly and may offer a new preventive treatment for osteoporosis.
A new study from the University of Kansas reviewed data from 22 preclinical studies and 14 clinical studies, finding no significant reduction in symptoms of anxiety in humans. However, researchers suggest that probiotics may have potential benefits for anxiety and cognitive issues in the future.
A new probiotic mix of natural and engineered bacteria can diagnose and treat cholera by detecting a specific molecule and producing an enzyme that kills the bacteria. This approach offers an inexpensive and quick means to track the disease and provide treatment, potentially replacing traditional antibiotics.
Scientists have developed a new vaccine-based intervention that reduces severity and increases survival times in animal models. A probiotic bacterial species, Lactococcus lactis, has also been found to combat cholera by producing an acid that kills the bacteria.
A study from McGill University found that combining probiotics with an herbal supplement called Triphala increases fruit fly lifespan by 60%. The researchers observed reduced traits of aging, including insulin resistance, inflammation, and oxidative stress. The findings suggest a potential link between gut bacteria and human longevity.
Researchers developed an animal probiotic that can reduce methane emissions and prevent nitrite poisoning in cattle. The probiotic uses a bacteria-based approach to increase feed efficiency and decrease pathogen carriage, with potential benefits for greenhouse gas reduction.
Researchers found that probiotics can decrease the mortality rate of nosemosis in bees by up to 40% and are as effective as commercial probiotics. The study suggests using beneficial bacteria from healthy bee microbiota to combat this disease.
A study found that vegan and traditional kimchi have nearly identical microbial communities after fermentation, with lactobacillus and leuconostoc dominating the samples. The findings suggest that vegan kimchi can provide probiotic benefits similar to traditional kimchi.
Two studies published in Infection Control & Hospital Epidemiology found that multi-strain probiotics reduced CDI incidence rates by about two-thirds. Probiotics were especially effective among participants taking two or more antibiotics, suggesting a potential prevention tool for hospital settings.
A new study suggests that probiotics can improve liver health by reducing oxidative stress caused by acetaminophen. Researchers found that mice treated with the probiotic Lactobacillus rhamnosus GG suffered less liver damage when exposed to a high dose of acetaminophen.
Observational research suggests that probiotic intake during late pregnancy may lower the risk of pre-eclampsia and premature birth. A significant association was found between probiotic consumption and a 20% lower risk of pre-eclampsia, while an 11% lower risk was observed for premature birth during early pregnancy.
A new study by Aarhus University suggests that certain lactic acid bacteria can prevent depressive-like behavior in rats fed an unhealthy diet. The probiotics offset the consequences of the fatty diet, reducing inflammation and improving brain function.
A new randomized controlled trial found that using probiotics and xylitol chewing gum has no effect on alleviating sore throat symptoms. Researchers suggest simple over-the-counter treatments may be more effective, enabling self-management and reducing antibiotic use.
Researchers found that Bifidobacterium administration reduced weight loss and inflammatory cytokine levels in mice with colitis, while preserving antitumor immunity. This suggests a potential role for intestinal microbiota in cancer immunotherapy.
A new study suggests that breast milk can help sustain beneficial probiotic colonies in infants' guts, leading to improved gut health. The research, published in mSphere, used a three-week course of probiotics and found that the beneficial microbes persisted for at least 30 days after treatment.
A study published in Nature found that common salt reduces certain lactic acid bacteria in the gut of mice and humans, impacting immune cells responsible for autoimmune diseases and hypertension. Probiotics ameliorate disease symptoms in mice.
A study found that a high-salt diet shrinks beneficial gut bacteria, leading to pro-inflammatory immune cells and high blood pressure. Probiotics can reverse these effects in mice and humans, suggesting potential therapeutic target for treating high blood pressure.
Researchers at Kent State University will investigate the use of probiotics during exercise in a hot environment. The study aims to understand how probiotic supplementation affects physical performance, psychological status, and cognitive function under heat stress.
A study of patients with recurrent Clostridium difficile (C. diff) infections found that many changed their behaviors, including increased hand washing and use of soap and water. However, certain dietary changes and probiotic supplements showed little evidence to reduce the risk of future infections.
Julia Oh has received a $2.8 million NIH grant to explore engineered probiotic treatments for skin diseases. Her research aims to harness the skin microbiome to create new therapeutics.
A new study found that administering a histamine-producing probiotic reduced inflammation and suppressed colon tumors in mice. The probiotic increased expression of the enzyme histidine decarboxylase, which converts histidine to histamine, resulting in decreased glucose uptake and tumor formation.
Researchers have identified a particular type of bacteria that may help break down lactic acid, leading to reduced muscle fatigue and soreness after intense exercise. The team also found niche microbiomes for different sports, suggesting potential benefits for various athletes.
A study found that a next-generation probiotic, Lactobacillus reuteri, produces an antibacterial compound that selectively kills C. difficile. This could lead to a preventative strategy for reducing the risk of C. difficile infections in patients taking antibiotics.
This research reviews the use of probiotics for producing metallic nanoparticles (MNPs), which have potential applications in treating diseases and diagnosing conditions. Gold, silver, copper and zinc oxide NPs are suggested for drug delivery, antimicrobial activity, and anti-corrosive properties.
A recent study by UMass Amherst researchers found that certain beneficial gut bacteria can grow when fed a carbohydrate in cranberries, exhibiting a special nontypical metabolism. The findings could lead to new supplements or food products with potential health benefits.
Researchers found that probiotics can improve immunity in fruit flies exposed to pesticides, a common model for studying honey bee effects. This mechanism could lead to improved survival rates for honey bees exposed to pesticide toxins, with potential benefits for agriculture and human health.
A McMaster University study found that a specific probiotic improved both gut and psychological symptoms in adults with irritable bowel syndrome (IBS) and mild to moderate anxiety or depression. The pilot study showed significant improvements in depression scores, associated with changes in brain areas involved in mood control.
Researchers found that Candida yeast infections contribute to bowel difficulties in men with schizophrenia. Probiotics also decreased delusions and hallucinations in participants without a history of yeast infections. Larger studies are needed to validate these findings and determine their effectiveness for women with schizophrenia.
Researchers found that probiotics had little impact on microbial diversity and even impaired recognition memory in rats on a balanced diet. However, for rats fed a junk diet, probiotics positively changed the bacterial make-up in their digestive tract and benefitted brain function, preventing spatial memory loss.
Researchers found that a probiotic combination of lactobacilli and bifidobacteria may alleviate mild seasonal allergy symptoms by increasing tolerance to hay fever. Participants who took the probiotic reported improvements in quality of life, including fewer nose symptoms and increased comfort during daily activities.
A recent study published in Frontiers in Behavioral Neuroscience suggests that prebiotic fibers can promote beneficial gut bacteria and recovery of normal sleep patterns after a stressful event. Regular intake of prebiotics may provide a natural way to cope with stress and support overall health.
New research reveals the mechanism by which probiotic Lactobacillus paracasei DG promotes health. The probiotic releases a novel polysaccharide that stimulates the immune system to release anti-inflammatory chemicals.
Researchers found that common probiotic Lactobacillus plantarum decreases stress-related behavior and anxiety in zebrafish, leading to increased signaling of neurotransmitters. Probiotics may have a positive impact on human stress levels, as their effects on the central nervous system are being studied.
A daily dose of probiotic Lactobacillus and Bifidobacterium bacteria taken over 12 weeks significantly improved the Mini-Mental State Examination (MMSE) score in Alzheimer's patients, indicating a moderate but significant improvement in cognitive function. This is the first study to show that probiotics can benefit human cognition.
Psychobiotics examines emerging strategies for planting brain-altering bacteria in the gut to provide mental benefits. Researchers agree that key players, including the nervous system and immune system, are involved in the gut-brian axis.
Research suggests that spinal cord injuries alter the type of bacteria living in the gut, exacerbating neurological damage and impairing recovery. Probiotics may counteract these changes, aiding patients' recovery from spinal cord injuries by activating regulatory T cells and promoting neuronal growth.
A new review found that certain alternative therapies, such as probiotics and fiber, are effective in treating IBS symptoms. Patients with functional constipation and ulcerative colitis may also benefit from synbiotics and Escherichia coli strain Nissle 1917.
Researchers found that a specific strain of Bifidobacterium longum AH1206 can establish itself in the human gut and remain there for up to 6 months. The study suggests that individualized features of the resident microbiome play a crucial role in the persistence of this strain, enabling personalized probiotic treatments.
Scientists discovered that a common intestinal microbe produces an enzyme called SagA, which protects worms and mammals from harmful bacteria like Salmonella typhimurium. The findings could lead to the development of probiotics against Clostridium difficile, a leading cause of hospital-acquired infections.
A randomized trial involving 1,302 asthmatic patients found no evidence to support the effectiveness of orally administered probiotics in reducing respiratory tract infections and antibiotic use. In contrast, a review of psychological interventions for postnatal depression found that community-based therapies were effective treatment o...
A 20-year study shows that probiotic supplementation in newborns can provide long-term protection against allergies. Meanwhile, a new vaccine for cat allergies lasts 8 times longer than existing ones, while research on dairy farm kids' immunity to milk allergies may lead to an asthma vaccine.
A new study finds that probiotic bacteria can reduce cadmium absorption in the intestines of mice by mitigating oxidative stress. The research provides evidence that probiotics can inhibit the toxic effects of cadmium on the gut barrier, potentially offering a solution to heavy metal contamination in public health.
A mouse study reveals that antibiotics can kill off gut bacteria and stop new brain cell growth in the hippocampus. However, probiotics and exercise have been shown to improve memory and neurogenesis by balancing the communication between the brain, immune system, and gut.
A systematic review of seven randomized controlled trials found little evidence of an effect of probiotics on the gut microbiota of healthy adults. The study suggested that measuring the effect of probiotics in healthy individuals is more difficult due to the lack of a clear definition of a normal or healthy fecal microbial community.