The Luxembourg AI Factory released an open-source tool to accelerate testing for trustworthy artificial intelligence. The AI Assessment Sandbox Configurator enables rigorous AI testing at scale, addressing regulatory requirements and ensuring trustworthiness.
The ERC Consolidator Grant will support advanced microscopy and spectroscopic analysis to examine bacteria's interaction with light, potentially leading to new imaging technologies. This research may inspire Living Photonic Circuits where organelles control and guide light paths within living cells.
A recent study found a potential link between air pollution and cognitive impairment, with fine particulate matter exposure correlating with declined cognitive processing time. Systemic inflammation, driven by an increase in monocytes, may act as a key intermediary linking PM2.5 exposure to impaired cognitive function.
Microglia establish contact with neurons through tunnelling nanotubes to clear toxic protein aggregates, reducing oxidative stress and restoring vital functions. Healthy mitochondria are also transferred from microglia to affected neurons, preserving energy production and neuronal survival.
Researchers developed a deep-learning model to predict atrial fibrillation, giving early warnings with an accuracy of around 80%. The model, called WARN, uses heart rate data to calculate a probability of danger, providing crucial time for preventive measures.
Researchers developed a novel modeling approach to predict microbial community behavior, improving sustainability and efficiency of biological wastewater treatment. The new framework uses high-resolution molecular data to forecast composition and activity of microbial communities up to three years into the future.
Experts have developed a reliable method to predict the free energy of crystals, addressing the challenge of understanding physical properties and environmental factors. The new approach uses high-performance computing and has been successfully applied to seven pharmaceutical companies.
A new computational approach enables the design of molecules with targeted quantum-mechanical properties, finding that most properties are only weakly correlated among small molecules. The 'freedom of design' concept reveals an intrinsic flexibility in chemical compound space, allowing for simultaneous optimization of multiple properties.
Researchers propose a new interpretation of dark energy, linking zero-point fluctuations to polarisability of the vacuum. This leads to an energy density that can be calculated and matches measured values for the cosmological constant.
Researchers discovered that damaged cells and aging induce high levels of oxidative stress and DNA damage in a subset of cells, leading to senescence. Senescent cells repress muscle regeneration by releasing inflammatory factors, while also promoting fibrosis, highlighting the need to remove these cells for improved repair.
Researchers at the University of Luxembourg created colour-changing CLCE fibres that can be easily sewn into fabric, shifting colours continuously from red to blue upon stretching, and remain colourful even after repeated wear and washing.
A study by Thorsten Lehnert shows that corporate managers' behavior is linked to investor sentiment, predicting investment strategy success. The researcher found a significant relationship between market-level euphoria and investment factor performance, outperforming static strategies.
Researchers developed a neural network algorithm to predict art auction prices, relying on visual and non-visual characteristics of artworks. While human experts were more accurate, the algorithm showed promise in identifying market inefficiencies, such as auctioneer biases.
The University of Luxembourg is pioneering the use of machine learning to identify potent drug candidates and accelerate pharmaceutical development. By combining quantum mechanics and large molecular datasets, researchers hope to overcome challenges in chemical discovery and create novel compounds with tailored properties.
Researchers at University of Luxembourg have identified a genetic form of Parkinson's disease caused by a splicing error, offering new potential pharmacological treatments. The discovery was made using patient-based cell cultures reprogrammed into nerve cells in vitro.
The exposome concept captures diverse environmental factors affecting human health, including chemicals in air, water, and food. Recent technological advances and analytical tools are crucial for identifying unknown chemicals and their impact on health.
The LCSB researchers are coordinating an international collaboration to build a COVID-19 Disease Map, a comprehensive repository of virus-host interaction mechanisms. The map will support research and improve our understanding of the disease by providing a graphical, interactive representation of the disease mechanisms.
A team of researchers found a security flaw in biometric passports that enables unauthorized equipment to scan and track passport holders' locations. The ICAO 9303 standard used worldwide since 2004 is vulnerable to attacks, posing a risk to individual privacy.
Researchers developed a computer model that simulates the metabolism of cancer cells, identifying effective drug combinations and predicting tumor growth inhibition. The model has been tested for colorectal cancer and shows promise for other types of cancer, potentially reducing development time and cost.
A combination of prebiotics and probiotics reduces the expression of pro-carcinogenic genes and may help treat colorectal cancer. The study used a unique gut-on-a-chip model to investigate diet-microbiome-host interactions, revealing a mechanistic basis for the observed beneficial effects.
Researchers at the University of Luxembourg have discovered a method to create an anti-ordered state in liquid crystals, which can exhibit unique properties such as shape-changing behavior. This breakthrough enables the development of novel materials with potential applications in soft robotics and artificial muscles.
RepuCoin introduces a reputation-based system that makes it difficult for attackers to control the network. The longer the system runs, the more resilient it becomes to attacks, with an attacker needing thousands of times more computational power to breach security.
Researchers from the University of Luxembourg have demonstrated a comprehensive understanding of neutron scattering techniques for analyzing magnetic materials. The study focuses on analysis techniques for superconductors, permanent magnets, shape-memory alloys, ferrofluids and other magnetic materials.
Researchers at LCSB and DKFZ successfully rejuvenated stem cells in the aging brain of mice, improving regeneration of injured areas. The study identified a molecule called sFRP5 that keeps neuronal stem cells inactive, but neutralizing it allowed them to proliferate again.
A new method developed by researchers at the University of Luxembourg and others can predict how drug molecules arrange themselves in different energetic conditions, reducing the risk of formulation failures. This approach could help pharmaceutical companies avoid costly development errors and ensure their drugs function properly.
A study found that specific bacteria from the mother's gut stimulate the baby's immune responses during vaginal birth, but this transmission is impacted in children born by caesarean section. This may explain why caesarean-born children are more prone to chronic diseases.
Researchers studied thermodynamics of small nanomachines and found that synchronizing their movements triggers significant synergy effects, leading to greater overall energy output. The findings could potentially be used to improve efficiency of any machine.
Scientists from the University of Luxembourg have identified a molecular mechanism responsible for colon cancer cell spread and metastasis. A small molecule cluster, miR-371~373, was found to regulate colon cancer metastasis in aggressive, fast-growing cancer cells. Reactivation of this cluster slowed down metastatic cell growth.
Researchers developed a computational method to accurately predict cell subpopulation conversions, enabling potential applications in regenerative medicine. The platform, TransSyn, identifies subtle genetic differences between cell subtypes, allowing for targeted gene expression alteration and cell reprogramming.
The material has unique properties that could be used to guide autonomous vehicles or instruct robots in factories. Liquid crystal shells can reflect light highly selectively and change structure when exposed to certain impacts, enabling passive sensors for pressure and temperature detection.
Researchers refuted long-held beliefs about sodium's impact on solar cell production by demonstrating its dual effect: homogenizing elements within grains but slowing inter-grain homogenization. This finding could lead to improved manufacturing processes and new insights into solar cell production.
A study by Prof. Katrin Hussinger and Dr Maikel Pellens found an average drop in citations of 8-9% for previous colleagues of fraudulent scientists, impacting their career success and funding opportunities.
Researchers have developed the first three-dimensional computer model to represent human metabolic processes. This new tool, Recon3D, integrates structural data on over 4,000 metabolites and nearly 13,000 proteins, allowing for more accurate simulations of metabolic reactions and better understanding of diseases such as Parkinson's.
Researchers at the University of Luxembourg have discovered a new promising biomarker for colorectal cancer. The biomarker, MYO5B, has been found to decrease in concentration as the disease progresses, indicating lower chances of disease- and metastasis-free survival.
A research team has quantified blind spots in protein function, revealing that 30% of proteins with unknown functions are enzymes. This discovery has significant implications for understanding rare genetic diseases and could lead to a better insight into the onset and triggers of inherited metabolic diseases.
Researchers at the University of Luxembourg found that the financial press can have a significant impact on investor behavior and opinions. The experiment showed that positive news coverage led to a positive evaluation of stocks, while negative coverage had the opposite effect.
A new ERC Grant project, ELWar, investigates how war influences electoral behavior in six postwar Balkan states over three decades. The study aims to identify the agents of postwar politics and their impact on societal decisions made after violence.
Multilingual individuals face challenges when solving arithmetic tasks in a second language, relying on alternative thought processes and brain regions not observed in monolinguals. Functional magnetic resonance imaging revealed distinct brain activity patterns when using different languages.
Researchers found a difference in gut bacteria between Parkinson's patients and healthy individuals even at an early stage of the disease. Certain microbes are associated with non-motor symptoms like depression. The study aims to better understand the microbiome's role in the disease.
The project aims to improve the usage of digital technologies for research by developing new methods for analyzing historical newspapers. The team will use deep learning to correct errors in text recognition and enhance entity recognition using external data repositories.
Researchers at the University of Luxembourg have redefined the understanding of van der Waals interactions, discovering they can be repulsive in confined spaces. This new paradigm could have implications for pharmaceutical delivery, water desalination and photovoltaic devices.
A new computational method uses data from medical imaging to create a color-coded 'digital lego brain' model that predicts organ deformation under surgical action. This allows surgeons to virtually rehearse operations and anticipate potential complications.
The art market price index, compiled by Prof. Roman Kräussl, shows a significant decline in post-war and contemporary art prices, with a 21% drop in 2016. This confirms a burst of the market bubble, which had been growing since 2009.
A study by University of Luxembourg researchers found that press freedom positively impacts stock market volatility, leading to greater economic growth. Countries with high press freedom experience more frequent price jumps, but ultimately benefit from improved information processing and decision-making.
Researchers at the University of Luxembourg have successfully grown brain-like cultures from human stem cells, mirroring the structure and function of the midbrain. This breakthrough allows for the study of Parkinson's disease mechanisms and potential treatments, as well as reducing animal testing in brain research.
Researchers have identified a mechanism by which the body controls the fate of stem cells, allowing them to adapt and differentiate into various types of cells. This discovery can help improve the effectiveness of stem cell therapies, potentially leading to better treatments for diseases like Parkinson's.
A new computer model is being developed to simulate the mechanical properties of snow and predict its behavior in various scenarios. This model will enable more accurate forecasts for avalanches and help determine the load on buildings caused by snow.
A new bioinformatics tool called IMP has been developed to increase the transparency and reproducibility of biological experiments. It preserves computer programs in a frozen state, allowing for easy reprocessing and analysis of complex data.
Scientists at the University of Luxembourg developed Equihash, a memory-hard problem algorithm that resolves Bitcoin's centralization issue. This allows for more democratic digital currencies like Zcash, where users can contribute to mining with standard hardware, reducing investment costs and increasing decentralization.
USP9 gene may provide new starting point for developing active ingredients to treat Alzheimer's disease. The researchers found that USP9 has an indirect influence on tau protein, which is believed to play a significant role in the onset of Alzheimer's disease.