Researchers at Nagoya University have developed colorful pigments by combining fine silica particles and iron tannic acid, a safe and inexpensive alternative to conventional harmful color materials. The new pigments can be adjusted in color and viewing angle, opening up possibilities for everyday life.
Researchers at UCLA have identified a new drug delivery pathway that uses reengineered fat cells to deliver chemotherapy drugs directly to tumors, suppressing growth and preventing recurrence. The approach could also be applied to other lipid metabolism-related diseases.
A Canadian team found that the LRRK2 gene is associated with an increased risk of Parkinson's disease, Crohn's disease, and leprosy due to enhanced inflammation. The study suggests that treating excessive inflammation may lead to new treatments and prevention strategies for these diseases.
According to a new paper by OSU professor Jane Lubchenco, ocean-based activities have significant potential to help reach the 1.5-degree Celsius target by 2050. The report analyzes five categories of ocean-based solutions to reduce emissions, including renewable energy and protecting marine ecosystems.
Researchers found that blocking interleukin-11 protein with therapeutic antibodies can reverse lung fibrosis in a mouse model. This discovery holds promise for treating idiopathic pulmonary fibrosis (IPF), a life-threatening lung disease. Clinical trials are expected to begin by 2021.
A study published in The BMJ found that Scotland's minimum unit pricing policy has reduced alcohol purchases and consumption by households. The policy has been successful in targeting heavier drinkers and lower-income groups, with price increases greatest among those buying the most alcohol.
Researchers have engineered protein crystals that can generate magnetic forces many times stronger than previously reported. By introducing these crystals into living cells, scientists can move the cells around with a magnet, offering potential applications in fields such as biotechnology and biomedical engineering.
Researchers developed a needle-free 'exosome' treatment that reduces wrinkles in UV-exposed mice, improving skin health and collagen production. The treatment uses a jet of air to deliver medications deep into the skin, providing a more youthful appearance.
Researchers visualize dynamic water transport in soil and roots using neutron tomography, gaining insights into efficient water use in crop cultivation. The technique enables faster imaging, overcoming previous limitations to study rapid processes.
A study published in Mucosal Immunology reveals that ASC and NLRP3 are key players in maintaining innate immune homeostasis in the airway, independent of caspase-1. This alternative mechanism may provide a new understanding of different possible mechanisms involved in airway protection against microbial infections.
A new online calculator helps middle-aged women predict their risk of conditions like heart disease, stroke, and cancer. The tool accounts for multiple health conditions at once and identifies changing probabilities over time.
A new Stanford University study has found that a four-week combination therapy involving brief light flashes and cognitive behavioral therapy can increase teenagers' sleep duration by 43 minutes per night. The treatment helped teens adjust their body clocks and motivated them to try earlier bedtimes.
Marsh plants produce more stems that are noticeably smaller under high carbon dioxide, but adding nitrogen reverses this effect. This adaptation may help marshes absorb energy from storms and build soil, providing a defensive power against sea level rise.
Researchers at University of Missouri create 3D model showing how ligaments and joints in T. rex skull work, revealing it was stiffer than previously thought. This discovery could advance human and animal medicine by providing better models of joint interactions.
Researchers discovered a key signaling pathway in adult fly intestines that promotes intestinal regeneration after stress. This finding has potential applications for regenerative medicine, particularly in treating inflammatory bowel diseases and colorectal cancer.
A multidisciplinary team at the University of Pittsburgh is developing novel research paradigms to address the complex challenge of global waste through circular economy design. The project aims to advance fundamental science behind circular economy solutions, including product design and life-cycle assessment.
A study published in Translational Psychiatry identified elemental signatures in baby teeth unique to ADHD, autism, and co-occurring conditions. The researchers found that each condition has a distinct metabolic signature involving essential and toxic elements.
A new prediction system significantly increased palliative care consultations for seriously ill patients by 74%, according to a University of Pennsylvania study. The Palliative Connect trigger system uses predictive analytics to identify patients in need of palliative care consultation, leading to earlier and more effective interventions.
The study analyzed Trump's tweets from 2009 to 2018, identifying four style variations: conversational, campaigning, advisory, and engaged. These stylistic patterns suggest underlying communication strategies used by Trump during the 2016 campaign, including appealing to different audiences, defending criticism, and attacking opponents.
A survey of European citizens found a majority (58%) hold positive attitudes towards homelessness, while 30% have negative views. Positive attitudes were more common among urban residents and those who support homeless individuals.
A new physics curriculum that teaches energy first shows promise in helping university students develop their calculus skills, particularly those with lower math abilities. Students who took the new curriculum performed better in subsequent engineering classes and on standardized physics conceptual tests.
Researchers discovered a 'wave of brain maturation' occurring in children from age 9-12, corresponding with increased social and academic demands. This neurological development is linked to improved impulse control, cognitive processing, and executive function.
Researchers discovered that certain soil microbes can make plants more resistant to an aggressive disease, such as bacterial wilt caused by Ralstonia solanacearum. The study found that rare taxa and pathogen-suppressing bacteria are associated with healthy plant microbiomes.
A study using UK Biobank data found a genetic link between psychotic experiences and neuropsychiatric disorders. The research suggests that individuals with a genetic predisposition to psychosis may also be at increased risk for other mental health conditions.
A new nanotechnology-based process uses magnetic particle imaging to monitor chemotherapy concentrations in real-time, allowing doctors to adjust doses precisely. This innovation has the potential to minimize side effects and improve treatment outcomes for cancer patients.
The BESTMAP project aims to develop a new flexible and interoperable framework to monitor EU policy impacts on natural, social, and cultural assets in rural areas. Computer models will help build an operational framework to analyze the adoption of agri-environmental schemes.
A nationwide study reveals that schools serving disadvantaged and minority children teach as much to their students as those serving more advantaged kids. The learning gap disappears when students return to school after summer break, suggesting that schools are neutral in addressing inequality.
Fruit-eating monkeys show a preference for low ethanol concentrations in fermenting fruit, suggesting that sweetness and carbohydrate content are more important than calorie content. The findings do not support the idea of human alcoholism originating from primates' preference for alcohol-containing overripe fruit.
A new study from the University of Nebraska-Lincoln reveals that nearly 40% of Americans report politics as a source of stress, with one in five experiencing lost sleep. The research also found that exposure to media promoting opposing views can drive individuals crazy and damage friendships.
Researchers have discovered a new species of ten-foot-long crocodile in New Guinea, separated from another by the island's mountain range. The species, Crocodylus halli, was named after Philip Hall, who first investigated the reptile's lineage.
A new compound derived from eushearilide has shown significant antibacterial properties against various disease-causing bacteria, including MRSA. This finding offers relief for immunocompromised people who are susceptible to life-threatening fungal and bacterial infections.
A urine test that measures specific proteins found in urine can detect early-stage pancreatic cancer with nearly 95% accuracy. The UroPanc clinical study aims to validate this biomarker in a clinical setting, with the potential to develop a standardized urine test for clinicians to use as a diagnostic aid.
A researcher at the Oklahoma Tobacco Research Center has been awarded a five-year grant to study the long-term effects of vaping on human health. The study aims to examine the effects of vaping on respiratory function and determine if users become susceptible to other tobacco products.
The International Energy Agency argues that nuclear power can fill the gap in low-carbon electricity generation, but safety concerns and high costs are barriers. Nuclear reactors can generate energy with low greenhouse gas emissions like other low-carbon sources.
A new paper by FoodMinds explores the state of personalized wellness, posing questions about the science supporting this space and offering a look at its future. The firm anticipates drastic growth in the next 3-5 years, driven by AI-driven offerings and embeddables.
NASA's Global Precipitation Measurement mission detected scattered light rain from the remnants of Hurricane Kiko, which weakened to a remnant low-pressure area on September 24. The rainfall data is used by forecasters at NOAA's National Hurricane Center to improve forecasts.
A new satellite mission, SWOT, will enhance flood modeling globally, even in extensively studied regions. It will provide more accurate floodplain maps and predictions for areas affected by snowmelt, hurricanes, and ice jam breakup.
Scientists at Cincinnati Children's developed the world's first three-organoid system, growing a connected set of mini human organs including liver, pancreas, and biliary ducts. The breakthrough allows for studying organ function in concert, reducing animal-based medication studies and accelerating precision medicine.
Children with asthma who also have depression and anxiety are more likely to visit the ER, with a rate of 28 visits per 100 child years compared to 16 for those without mental health diagnoses. This population may benefit from more intensive care coordination to improve medication compliance and symptom recognition.
Acting on ocean-focused emissions activities can significantly contribute to reducing greenhouse gas emissions. The implementation of changes in research, technology, and policy development could lead to a substantial reduction in global emissions by nearly 11 billion tons in 2050.
Three studies from Cincinnati Children's Hospital Medical Center reveal a strong association between short-term air pollution exposure and exacerbations of psychiatric disorders in children, with higher risks for disadvantaged neighborhoods. The research also found links to generalized anxiety and depression in otherwise healthy children.
A new study warns that up to 60% of current wheat-growing areas could experience severe and prolonged droughts by the end of the century due to climate change. This would have a significant impact on global food production and lead to increased food prices.
Jerry has been designated a post-tropical cyclone due to the lack of strong thunderstorms in recent satellite imagery. The post-tropical storm is expected to produce 1 inch or less of rainfall across Bermuda through tonight, with swells continuing to affect the island over the next few days.
Researchers at Tokyo University of Agriculture and Technology developed a bouncing ball model to predict tractor overturns. The model aims to reduce the rate of overturned tractors, a leading cause of death for farmers worldwide.
Researchers observe anomalously large superconducting gap (~3.8 meV) in thin films of β-Bi2Pd, compared to bulk single crystals with a smaller gap. First-principle calculations suggest Dirac-fermion-mediated parity mixing may cause this enhancement.
Researchers found that people perceive truthfulness higher in claims following alphabetical order, even when source unknown. This can be exploited by companies to convince consumers of slogans or claims.
A study of adolescent and adult athletes found evidence of damage to the brain's protective barrier, without a reported concussion. The researchers detected leaks in the blood-brain barrier using advanced MRI protocol and biomarkers, suggesting that mild impact can still cause significant trauma.
New research reveals that coniferous forest aerosols no longer cool the climate as much, thanks to increased small airborne particles caused by human activities. The reduction of natural aerosols and increase of smaller particles diminish the cooling effect on the climate.
A new type of vaccine that can be stored at warmer temperatures has been developed for Chikungunya, a disease that causes crippling headache and joint pain. The vaccine candidate has shown exceptionally promising results in animal studies, setting the stage for a future vaccine to combat the disease.
Researchers found that big mammals have far more neutrophils in circulation than small species, a key defense against early immune responses to invaders like bacteria and parasites. Larger mammals may need more circulating neutrophils to overcome the advantage infectious agents have over them due to their size.
Researchers at the University of Alberta are developing a new treatment that could help almost half of patients with Duchenne muscular dystrophy by restoring dystrophin protein production. The experimental cocktail of DNA-like molecules has shown dramatic regrowth of dystrophin, which acts as a support beam to keep muscles strong.
Only half of patients with sinus, throat, ear infections received recommended first-line antibiotics, a rate below industry standard. Retail clinics and emergency departments had higher rates, while urgent care centers lagged.
Gun owners report fewer phobias and victimization fears than non-gun owners, study by Florida State University researchers suggests. The study found exceptions for fears of animals and mugging, and implications for gun policy.
Researchers demonstrate a method of transferring the state of electrons, a crucial step towards creating effective quantum computers. This achievement brings scientists one step closer to unlocking the full potential of quantum computing.
Compound lenses developed by researchers are inspired by mosquito eyes, providing a wide field of view with rapid imaging capabilities. The new design has antifogging properties, similar to those found in mosquito eyes, making it suitable for applications in drones, robots and medical devices.
A team of researchers has reported a new manufacturing method, CAS printing, to produce curvy electronic devices such as smart contact lenses and hemispherical solar cells. The technique enables the efficient production of three-dimensional curvy structures with high accuracy.
A novel player trait model has been developed to evaluate individual gaming preferences, enabling the creation of tailored experiences. The five-trait model assesses social, aesthetic, challenge, goal, and narrative elements to provide personalized game recommendations.
Researchers analyzed 1,309 gamers' playing history over 29 months, finding that varying game difficulty based on players' engagement levels increases use by 4-8%. The study suggests introducing surprises like new maps or game modes to offset decreased player curiosity.
The AIDS and Cancer Specimen Resource (ACSR) has been renewed for 5 years with a $22 million grant from the National Institutes of Health. The ACSR provides annotated HIV malignancy specimens to qualified researchers, supporting research into HIV-associated cancers.
A University of Michigan study found that Medicaid expansion improved the health, work, and job search outcomes of low-income adults with behavioral health conditions. Those with these conditions showed significant gains in physical and mental health, as well as better job performance.
The genome comparison of almond and peach trees sheds light on their evolutionary history and the role of mobile genetic elements in diversification. The study found that transposons may have driven the differences between the two species, including variations in flavor and fruit quality.
Researchers at TU Dresden and Ulm University developed a new synthetic route to create crystalline 2D polymers with defined structures. The 2D polymers have promising properties for electronic components and systems, including superior charge transport and chemiresistivity.
Researchers at the University of Würzburg are developing a new therapy approach using virtual reality avatars to combat obesity. The avatars aim to provide a realistic body image, promoting acceptance and self-reflection in patients struggling with the condition.
A study of nearly 25,000 patients found that weight-loss surgery in Western Australia was associated with higher rates of outpatient and emergency department mental health services. The research suggests that patients who undergo bariatric surgery may experience increased mental health needs after the procedure.
A recent study by Robert Hofmann and colleagues discovered that Tripolye mega-structures served as public spaces for ritual, economic, and decision-making purposes. The researchers found a hierarchy of mega-structures based on their architecture and location, indicating sequential decision-making at various levels of society.
Studies examine the effects of temperature on itchgrass and divine nightshade seeds in sugarcane fields. Higher temperatures can kill weeds, but varying conditions are needed for optimal control, considering seed coat structure and soil insulation.
A new research study has revealed that humans lived in a low-carbon-dioxide atmosphere for 2.5 million years, with concentrations averaging 230 parts per million, until 1965. Today's levels are about 410 parts per million.
Researchers have discovered a new drug target for Myelodysplastic Syndrome (MDS) by targeting an earlier stage of progenitor cells. Blocking the CHRM4 protein receptor significantly improves blood cell production in MDS patients. Preclinical tests in mice show sustained therapeutic efficacy.
Hurricane Lorenzo's cloud top temperatures dropped to minus 121 Fahrenheit, indicating increased strength, with maximum sustained winds reaching 85 mph. The storm is forecast to become a major hurricane by Thursday and will continue moving west-northwest.
A new study found that almost half of young African American children responded better to increasing inhaled corticosteroid doses than adding long-acting bronchodilators. For adolescents and adults, most showed improved responses with adding a long-lasting bronchodilator, but some had no difference.
African Americans have lower survival rates and shorter survival times after cancer diagnosis compared to other racial groups. A new NIH-funded study will investigate the impact of community, interpersonal, and individual factors on health-related quality of life for African American cancer survivors.
Researchers at Osaka University have developed a palladium-based alloy nanocatalyst that promotes the selective production of deuterium isotope compounds from formic acid. The catalyst enables a cost-effective and scalable process for producing these gases, which are useful in fine chemical production and research applications.
Researchers found that a fraction of the fish caught nearby could significantly improve health in tropical coastal areas. The study suggests that existing marine fisheries can substantially reduce malnutrition, but access to these nutrients is often restricted to those who need them most.
A recent study published in New Phytologist identified opportunities to boost cassava yields by optimizing photosynthesis. Researchers found that cassava's stomata limit photosynthesis during light transitions, and increasing the speed of these pores could increase yield potential by up to 6%.
PlaneEnglish, an app-based aviation radio simulator, has received a $50,000 grant from the Air Force to improve flight training. The simulator helps pilots acquire radio communication proficiency in realistic environments, enhancing situational awareness and response skills.
Pitt scientists found that film can capture nuanced opinions, emotions, and spaces beyond traditional methods, but also raises concerns about participant privacy and logistical challenges. Their collaborative filmmaking method empowers participants to express themselves comfortably through video presentations.
The prevalence of NAFLD is rising due to a preventable epidemic, with over half of adults and one third of children classified as overweight or obese. The condition is linked to lack of physical activity, excess calorie intake, and sugary drinks.
Researchers found that plastic teabags release a significant amount of micro- and nanoplastics into tea during brewing. The levels were thousands of times higher than previously reported in other foods, and treated water fleas showed anatomical and behavioral abnormalities.
A study of 123,000 patients found that those with mental health disorders had primary care visits before diagnosis and lower overall complication severity scores. Patients with existing mental health disorders also experienced more quickly progressing complications over seven years after diabetes diagnosis.
Researchers found that age has a greater impact on religiosity than cohort effects in high-income countries. This could lead to a shift in societal structures. As older people make up more of the population, there may be a resurgence of religiosity in countries like Japan.
A study published in the Journal of the American Heart Association found that on-the-job pesticide exposure raised the risk of heart disease and stroke in Japanese American men. After 34 years of follow-up, no significant link was found between pesticide exposure and cardiovascular disease.
A small study suggests that non-invasive nerve stimulation may be effective in treating vestibular migraine attacks. The treatment, which involves electrical impulses delivered through the skin to the vagus nerve, showed improvement in vertigo symptoms for 13 out of 14 participants.
Explore Interactive's augmented reality platform aims to help students learn about science, technology, engineering and mathematics (STEM) through hands-on challenges and design exercises. The NIH grant will enable the company to track growth in proficiency and provide real-time analytics for teachers.
Researchers developed a new laser-based system that uses speckle pattern analysis to detect fires in harsh environments. The system achieved an accuracy of 91 percent in tests at a waste plant in Denmark, offering a promising solution for fire detection in industrial settings.
MIT researchers analyzed 380,000 government service requests to find a way for cities to preserve citizen privacy while improving efficiency. They identified model cities that maximized both privacy and efficiency, suggesting similar methodologies for worldwide evaluation of government services.
Researchers at Baylor College of Medicine discovered that inactivating the Hippo pathway in cardiac fibroblasts promotes cardiac fibrosis and adversely affects cardiac function. This finding highlights the need for specific targeting of the Hippo pathway in cardiac muscle cells for safe and effective heart failure therapy.
A team of researchers found a security flaw in biometric passports that enables unauthorized equipment to scan and track passport holders' locations. The ICAO 9303 standard used worldwide since 2004 is vulnerable to attacks, posing a risk to individual privacy.
ECOG-ACRIN announces late-breaking TAILORx data on chemotherapy regimens for early-stage breast cancer. The data, published concurrently in JAMA Oncology, focuses on patients with a score of 26-100 on the 21-tumor gene recurrence score assay.
A stretchable and flexible biofuel cell has been developed to power wearable electronics using human sweat. The device continuously lights an LED and opens avenues for the development of reliable and efficient energy sources. Researchers are now seeking to amplify the voltage provided by the biofuel cell to power larger portable devices.
Researchers at UNIGE unveil a mutation mechanism essential for cancer development by linking DNA replication failures in cancer cells to their genetic instability. They successfully corrected the effects of replication stress in diseased cells, showing that this phenomenon is controllable and potentially exploitable for therapy.
Cancer cells adapt to treatment with checkpoint blocker drugs by altering a metabolic process, leading to shorter survival for patients. The study suggests that identifying biomarkers of metabolic changes related to treatment with checkpoint blockers could help identify patients who might benefit from combination therapy.
A new NASA visualization reveals how a black hole distorts space, creating a warped view of its surroundings like a carnival mirror. The extreme gravity bends light from the accretion disk, producing a misshapen appearance.
A study by the University of Pavia found that Mediterranean private boats have a high potential to spread alien species through biofouling. Boats traveling to new marinas were likely to be transporting alien species, with visible biofouling in niche areas such as ladders and propellers being key predictors of high species richness.
Researchers created CAR T cells targeting BAFF-R, a surface marker found on B cells and cancerous B cells. This approach showed promise in killing cancer cells that lack CD19, reducing the risk of relapse in patients with lymphoma.
A new study found that 13% of postmenopausal women veterans screened positive for military sexual trauma, strongly associated with mental health diagnoses like PTSD, depression, and suicidal ideation. The study highlights the need for additional research and trauma screening in this understudied population.
Researchers at Newcastle University found that higher water volumes in delicate wash cycles release more plastic microfibres than standard cycles. The team discovered that the volume of water used during the wash cycle is the key factor, not spinning action, and that this can lead to a significant increase in released fibres.
Researchers found that dual PPARα/γ agonists cause heart dysfunction in diabetes patients due to mitochondrial biogenesis and energy production issues. Activating SIRT1 with resveratrol reduced heart toxicity in mice treated with tesaglitazar, maintaining its therapeutic benefits.
Scientists at the University of Bristol discovered clay vessels from Europe dating back to 5,000 BC that were used as early baby bottles for animal milk. The analysis revealed ruminant milk residues from domesticated cattle, sheep, or goat.
A new study estimates that human decisions and actions can reduce the uncertainty in climate response, limiting economic impacts to under 1% of global GDP. The research suggests humanity has control over its future and can choose a path through its actions.
New research from Washington University School of Medicine shows that infectious disease specialists can significantly improve outcomes for hospitalized patients with fungal bloodstream infections. With a 20% lower risk of death and increased use of life-saving treatments, specialist consultation is crucial in reducing mortality rates.
A research project from the University of Otago is developing a ryegrass variety that can be induced to flower for seed production under artificial conditions. This could lead to more productive and efficient farming, increasing productivity and reducing land use while minimizing environmental impact.
A secret-shopper-style study by Harvard Medical School found that web-based and digital-app services offering oral contraception appear to be safe and efficient. However, gaps remain, such as inadequate counseling on alternative forms of birth control and lack of screening for rare health conditions.
Researchers observed flavobacteria forming tubes and then strings of pearls, which capture and break down laminarin sugar for nutrition. This ecological strategy appears successful, as the bacteria are found in large numbers after algal blooms.
The EXO-200 collaboration has established some of the strongest limits yet for neutrinoless double beta decay and two-neutrino double beta decay of xenon-136. This research sets the stage for future experiments that will search for the hypothetical process, which would confirm that neutrinos are their own antiparticles.
Researchers at the University of Strathclyde are working on a system to measure blood chemistry levels in premature and sick babies through their skin, which could replace invasive blood tests. The technology aims to collect glucose and lactate levels using a wireless patch sensor that can be placed on the baby's stomach.
A new experimental test made from bacterial innards has high potential as a basis for an inexpensive, easy malnutrition test for use in the field. The test can detect zinc levels and quantify clinically relevant levels, allowing aid agencies to get immediate information and influence policy decisions on nutritional interventions.
Duke University engineers used machine learning to design dielectric metamaterials that absorb and emit specific frequencies of terahertz radiation, reducing calculation time from over 2,000 years to just 23 hours. The new designs enable thermophotovoltaic devices that convert waste heat to electricity with higher efficiency.
UIC researchers have successfully developed a fully rechargeable prototype of a lithium-carbon dioxide battery, demonstrating its potential for advanced energy storage systems. The battery's efficiency and long-lasting cycle life are significantly improved due to the use of new materials and a hybrid electrolyte.
Tropical Storm Karen has brought heavy rain to Puerto Rico, with the GPM core satellite detecting rainfall rates exceeding 1.6 inches per hour in the Atlantic Ocean and central Puerto Rico. Forecasters predict additional rainfall accumulations of 1-2 inches across the territory.
Researchers have created a rewriteable paper coating that can encrypt secret information using relatively low-tech invisible ink--water. The method allows reversible secure printing for at least 30 cycles, significantly reducing the cost and being environmentally friendly.
The Chan Zuckerberg Initiative funds I AM ALS to create open source digital tools for building a movement against ALS and other rare diseases. This support aims to connect patients, caregivers, and scientists to accelerate progress in finding treatments and cures.
Food insecurity has serious consequences for health and wellbeing, including inadequate intake of key nutrients, depression, and poor physical and mental health. Experts propose strategies such as improving weekend access to nutritious foods during summer months and understanding the psychosocial effects of food insecurity on college s...
A study found that substantial school spending cuts during the Great Recession led to significant losses in academic achievement for students living in counties most affected by the economic downturn. The estimated declines in student math and English language arts achievement represent a loss of approximately 25 percent of expected an...
New research finds that millions of people worldwide are suffering from micronutrient deficiencies, which can be reduced by increasing access to fish caught near their homes. The study suggests that current fishing practices and trade in seafood are standing between malnourished populations and the nutrients they need.
Men who became fathers through assisted reproduction techniques have a higher risk of prostate cancer and early onset prostate cancer compared to those who conceived naturally. Early screening and long-term monitoring are advised for these men.
Using laser pulses, researchers successfully induced superconductivity in an iron-based compound at a temperature of minus 258 degrees Celsius. This breakthrough could lead to more power-efficient devices and infrastructure if it can be scaled up to room-temperature applications.
A recent study has identified FHL1 protein as a crucial cellular factor for the replication and pathogenesis of chikungunya virus. The researchers found that FHL1 interacts with viral protein nsP3 to facilitate viral infection, making it a promising target for antiviral development.
Researchers at City of Hope have developed a new CAR T cell therapy targeting the B cell-activating factor receptor (BAFF-R), which showed remarkable tumor regression and prolonged survival in animal models. The therapy may potentially be used as a first-line treatment for patients who relapsed after CD19 immunotherapy treatments.
Researchers used a new technique to identify genetic profiles of individual cells in a breast cancer tumor and found a drug combination that reversed resistance. The study suggests that clinicians could begin combination therapy before resistance occurs, given the effectiveness of the additional drug.
Researchers are combining supply chain and conservation datasets to predict and respond to weaknesses in illegally trafficked wildlife supply chains. The team aims to develop tools to interfere with wildlife trafficking, potentially influencing other transnational crimes.
Cetaceans lost genes for saliva secretion and lung function to adapt to aquatic life. They also shed melatonin production genes, leading to novel sleep patterns where one brain hemisphere stays awake to generate heat as needed.
A Phase 1B study led by the University of Texas MD Anderson Cancer Center demonstrated positive safety results for pegilodecakin when combined with pembrolizumab and nivolumab. The treatment showed promising anti-tumor activity in patients with non-small cell lung cancer and kidney cancer.